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Volumn 121, Issue 6, 2011, Pages 2065-2073

The three R's of lung health and disease: Repair, remodeling, and regeneration

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LUNG INJURY; BIRT HOGG DUBE SYNDROME; CELL DAMAGE; CELL LINEAGE; CELL PROLIFERATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLARA CELL; HOMEOSTASIS; HUMAN; INTERSTITIAL PNEUMONIA; LUNG ALVEOLUS EPITHELIUM; LUNG DEVELOPMENT; LUNG DISEASE; LUNG DYSPLASIA; LUNG FIBROSIS; LUNG INJURY; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY DISTRESS SYNDROME; REVIEW; STEM CELL; TISSUE REGENERATION; TISSUE REPAIR;

EID: 79957922264     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI45961     Document Type: Review
Times cited : (261)

References (89)
  • 1
    • 33744524149 scopus 로고    scopus 로고
    • Regulation of early lung morphogenesis: Questions, facts and controversies
    • DOI 10.1242/dev.02310
    • Cardoso WV, Lu J. Regulation of early lung morphogenesis: questions, facts and controversies. Development. 2006;133(9):1611-1624. (Pubitemid 43810969)
    • (2006) Development , vol.133 , Issue.9 , pp. 1611-1624
    • Cardoso, W.V.1    Lu, J.2
  • 2
    • 50849104286 scopus 로고    scopus 로고
    • Resident cellular components of the lung: Developmental aspects
    • Cardoso WV, Whitsett JA. Resident cellular components of the lung: developmental aspects. Proc Am Thorac Soc. 2008;5(7):767-771.
    • (2008) Proc Am Thorac Soc , vol.5 , Issue.7 , pp. 767-771
    • Cardoso, W.V.1    Whitsett, J.A.2
  • 3
    • 74049139927 scopus 로고    scopus 로고
    • Preparing for the first breath: Genetic and cellular mechanisms in lung development
    • Morrisey EE, Hogan BL. Preparing for the first breath: genetic and cellular mechanisms in lung development. Dev Cell. 2010;18(1):8-23.
    • (2010) Dev Cell , vol.18 , Issue.1 , pp. 8-23
    • Morrisey, E.E.1    Hogan, B.L.2
  • 4
    • 0036314791 scopus 로고    scopus 로고
    • Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction
    • Giangreco A, Reynolds SD, Stripp BR. Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction. Am J Pathol. 2002;161(1):173-182. (Pubitemid 34760783)
    • (2002) American Journal of Pathology , vol.161 , Issue.1 , pp. 173-182
    • Giangreco, A.1    Reynolds, S.D.2    Stripp, B.R.3
  • 6
    • 70450196056 scopus 로고    scopus 로고
    • The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells
    • Rawlins EL, Clark CP, Xue Y, Hogan BL. The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells. Development. 2009;136(22):3741-3745.
    • (2009) Development , vol.136 , Issue.22 , pp. 3741-3745
    • Rawlins, E.L.1    Clark, C.P.2    Xue, Y.3    Hogan, B.L.4
  • 7
    • 69149106207 scopus 로고    scopus 로고
    • Basal cells as stem cells of the mouse trachea and human airway epithelium
    • Rock JR, et al. Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci U S A. 2009;106(31):12771-12775.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.31 , pp. 12771-12775
    • Rock, J.R.1
  • 10
    • 2342620855 scopus 로고    scopus 로고
    • Epithelial-mesenchymal interactions in the developing lung
    • Shannon JM, Hyatt BA. Epithelial-mesenchymal interactions in the developing lung. Annu Rev Physiol. 2004;66:625-645.
    • (2004) Annu Rev Physiol , vol.66 , pp. 625-645
    • Shannon, J.M.1    Hyatt, B.A.2
  • 11
    • 0032947875 scopus 로고    scopus 로고
    • Induction of alveolar type II cell differentiation in embryonic tracheal epithelium in mesenchyme-free culture
    • Shannon JM, Gebb SA, Nielsen LD. Induction of alveolar type II cell differentiation in embryonic tracheal epithelium in mesenchyme-free culture. Development. 1999;126(8):1675-1688.
    • (1999) Development , vol.126 , Issue.8 , pp. 1675-1688
    • Shannon, J.M.1    Gebb, S.A.2    Nielsen, L.D.3
  • 12
    • 34748900267 scopus 로고    scopus 로고
    • Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells
    • DOI 10.1016/j.ydbio.2007.08.007, PII S0012160607012523
    • Lu Y, Thomson JM, Wong HY, Hammond SM, Hogan BL. Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev Biol. 2007;310(2):442-453. (Pubitemid 47483685)
    • (2007) Developmental Biology , vol.310 , Issue.2 , pp. 442-453
    • Lu, Y.1    Thomson, J.M.2    Wong, H.Y.F.3    Hammond, S.M.4    Hogan, B.L.M.5
  • 13
    • 17244375059 scopus 로고    scopus 로고
    • Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation
    • DOI 10.1242/dev.01678
    • Okubo T, Knoepfler PS, Eisenman RN, Hogan BL. Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation. Development. 2005;132(6):1363-1374. (Pubitemid 40528795)
    • (2005) Development , vol.132 , Issue.6 , pp. 1363-1374
    • Okubo, T.1    Knoepfler, P.S.2    Eisenman, R.N.3    Hogan, B.L.M.4
  • 14
    • 69549090537 scopus 로고    scopus 로고
    • Multiple roles for Sox2 in the developing and adult mouse trachea
    • Que J, Luo X, Schwartz RJ, Hogan BL. Multiple roles for Sox2 in the developing and adult mouse trachea. Development. 2009;136(11):1899-1907.
    • (2009) Development , vol.136 , Issue.11 , pp. 1899-1907
    • Que, J.1    Luo, X.2    Schwartz, R.J.3    Hogan, B.L.4
  • 16
    • 18244377210 scopus 로고    scopus 로고
    • Wnt/beta-catenin pathway
    • Moon RT. Wnt/beta-catenin pathway. Sci STKE. 2005;2005(271):cm1.
    • (2005) Sci STKE , vol.2005 , Issue.271
    • Moon, R.T.1
  • 18
    • 3042840059 scopus 로고    scopus 로고
    • Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm
    • Okubo T, Hogan BL. Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. J Biol. 2004;3(3):11.
    • (2004) J Biol , vol.3 , Issue.3 , pp. 11
    • Okubo, T.1    Hogan, B.L.2
  • 19
    • 70349211744 scopus 로고    scopus 로고
    • Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway
    • Cohen ED, Ihida-Stansbury K, Lu MM, Panettieri RA, Jones PL, Morrisey EE. Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway. J Clin Invest. 2009;119(9):2538-2549.
    • (2009) J Clin Invest , vol.119 , Issue.9 , pp. 2538-2549
    • Cohen, E.D.1    Ihida-Stansbury, K.2    Lu, M.M.3    Panettieri, R.A.4    Jones, P.L.5    Morrisey, E.E.6
  • 20
    • 68349092814 scopus 로고    scopus 로고
    • Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut
    • Goss AM, et al. Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Dev Cell. 2009;17(2):290-298.
    • (2009) Dev Cell , vol.17 , Issue.2 , pp. 290-298
    • Goss, A.M.1
  • 21
    • 70349519044 scopus 로고    scopus 로고
    • Beta-Catenin promotes respiratory progenitor identity in mouse foregut
    • Harris-Johnson KS, Domyan ET, Vezina CM, Sun X. beta-Catenin promotes respiratory progenitor identity in mouse foregut. Proc Natl Acad Sci U S A. 2009;106(38):16287-16292.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.38 , pp. 16287-16292
    • Harris-Johnson, K.S.1    Domyan, E.T.2    Vezina, C.M.3    Sun, X.4
  • 27
    • 33646705916 scopus 로고    scopus 로고
    • FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains
    • DOI 10.1242/dev.02313
    • White AC, Xu J, Yin Y, Smith C, Schmid G, Ornitz DM. FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains. Development. 2006;133(8):1507-1517. (Pubitemid 43732964)
    • (2006) Development , vol.133 , Issue.8 , pp. 1507-1517
    • White, A.C.1    Xu, J.2    Yin, Y.3    Smith, C.4    Schmid, G.5    Ornitz, D.M.6
  • 28
    • 0034956610 scopus 로고    scopus 로고
    • Lung hypoplasia and neonatal death in Fgf9-null mice identify this gene as an essential regulator of lung mesenchyme
    • Colvin JS, White AC, Pratt SJ, Ornitz DM. Lung hypoplasia and neonatal death in Fgf9-null mice identify this gene as an essential regulator of lung mesenchyme. Development. 2001;128(11):2095-2106. (Pubitemid 32600470)
    • (2001) Development , vol.128 , Issue.11 , pp. 2095-2106
    • Colvin, J.S.1    White, A.C.2    Pratt, S.J.3    Ornitz, D.M.4
  • 29
    • 0035213812 scopus 로고    scopus 로고
    • The bone morphogenic protein antagonist gremlin regulates proximal-distal patterning of the lung
    • DOI 10.1002/dvdy.1231
    • Lu MM, Yang H, Zhang L, Shu W, Blair DG, Morrisey EE. The bone morphogenic protein antagonist gremlin regulates proximal-distal patterning of the lung. Dev Dyn. 2001;222(4):667-680. (Pubitemid 33136337)
    • (2001) Developmental Dynamics , vol.222 , Issue.4 , pp. 667-680
    • Lu, M.M.1    Yang, H.2    Zhang, L.3    Shu, W.4    Blair, D.G.5    Morrisey, E.E.6
  • 30
    • 0032857527 scopus 로고    scopus 로고
    • Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development
    • Weaver M, Yingling JM, Dunn NR, Bellusci S, Hogan BL. Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development. Development. 1999;126(18):4005-4015. (Pubitemid 29481558)
    • (1999) Development , vol.126 , Issue.18 , pp. 4005-4015
    • Weaver, M.1    Yingling, J.M.2    Dunn, N.R.3    Bellusci, S.4    Hogan, B.L.M.5
  • 31
    • 33644764648 scopus 로고    scopus 로고
    • Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells
    • DOI 10.1016/j.ydbio.2005.12.006, PII S0012160605008766
    • Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL. Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006;291(1):67-82. (Pubitemid 43343927)
    • (2006) Developmental Biology , vol.291 , Issue.1 , pp. 67-82
    • Eblaghie, M.C.1    Reedy, M.2    Oliver, T.3    Mishina, Y.4    Hogan, B.L.M.5
  • 32
    • 34250688302 scopus 로고    scopus 로고
    • Foxp2 and Foxp1 cooperatively regulate lung and esophagus development
    • DOI 10.1242/dev.02846
    • Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE. Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development. 2007;134(10):1991-2000. (Pubitemid 46939243)
    • (2007) Development , vol.134 , Issue.10 , pp. 1991-2000
    • Shu, W.1    Lu, M.M.2    Zhang, Y.3    Tucker, P.W.4    Zhou, D.5    Morrisey, E.E.6
  • 33
    • 0037083525 scopus 로고    scopus 로고
    • Increased expression of thyroid transcription factor-1 (TTF-1) in respiratory epithelial cells inhibits alveolarization and causes pulmonary inflammation
    • DOI 10.1006/dbio.2001.0540
    • Wert SE, Dey CR, Blair PA, Kimura S, Whitsett JA. Increased expression of thyroid transcription factor-1 (TTF-1) in respiratory epithelial cells inhibits alveolarization and causes pulmonary inflammation. Dev Biol. 2002;242(2):75-87. (Pubitemid 34163972)
    • (2002) Developmental Biology , vol.242 , Issue.2 , pp. 75-87
    • Wert, S.E.1    Dey, C.R.2    Blair, P.A.3    Kimura, S.4    Whitsett, J.A.5
  • 35
    • 41549108935 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Aberrant recapitulation of developmental programs?
    • Selman M, Pardo A, Kaminski N. Idiopathic pulmonary fibrosis: aberrant recapitulation of developmental programs? PLoS Med. 2008;5(3):e62.
    • (2008) PLoS Med , vol.5 , Issue.3
    • Selman, M.1    Pardo, A.2    Kaminski, N.3
  • 36
    • 34548022855 scopus 로고    scopus 로고
    • Cystic lung disease in Birt-Hogg-Dubé syndrome
    • DOI 10.1378/chest.07-0042
    • Ayo DS, Aughenbaugh GL, Yi ES, Hand JL, Ryu JH. Cystic lung disease in Birt-Hogg-Dube syndrome. Chest. 2007;132(2):679-684. (Pubitemid 47282405)
    • (2007) Chest , vol.132 , Issue.2 , pp. 679-684
    • Ayo, D.S.1    Aughenbaugh, G.L.2    Yi, E.S.3    Hand, J.L.4    Ryu, J.H.5
  • 38
    • 33744924735 scopus 로고    scopus 로고
    • Role of epithelial cells in idiopathic pulmonary fibrosis: From innocent targets to serial killers
    • DOI 10.1513/pats.200601-003TK
    • Selman M, Pardo A. Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers. Proc Am Thorac Soc. 2006;3(4):364-372. (Pubitemid 43845414)
    • (2006) Proceedings of the American Thoracic Society , vol.3 , Issue.4 , pp. 364-372
    • Selman, M.1    Pardo, A.2
  • 39
    • 1642453778 scopus 로고    scopus 로고
    • Endothelial Dysfunction in Pulmonary Hypertension
    • DOI 10.1161/01.CIR.0000102381.57477.50
    • Budhiraja R, Tuder RM, Hassoun PM. Endothelial dysfunction in pulmonary hypertension. Circulation. 2004;109(2):159-165. (Pubitemid 38114133)
    • (2004) Circulation , vol.109 , Issue.2 , pp. 159-165
    • Budhiraja, R.1    Tuder, R.M.2    Hassoun, P.M.3
  • 40
    • 0036126333 scopus 로고    scopus 로고
    • Mutations in the surfactant protein C gene associated with interstitial lung disease
    • Nogee LM, Dunbar AE 3rd, Wert S, Askin F, Hamvas A, Whitsett JA. Mutations in the surfactant protein C gene associated with interstitial lung disease. Chest. 2002;121(3 suppl):20S-21S.
    • (2002) Chest , vol.121 , Issue.3 SUPPL.
    • Nogee, L.M.1    Dunbar III, A.E.2    Wert, S.3    Askin, F.4    Hamvas, A.5    Whitsett, J.A.6
  • 41
    • 0035931973 scopus 로고    scopus 로고
    • A mutation in the surfactant protein C gene associated with familial interstitial lung disease
    • DOI 10.1056/NEJM200102223440805
    • Nogee LM, Dunbar AE 3rd, Wert SE, Askin F, Hamvas A, Whitsett JA. A mutation in the surfactant protein C gene associated with familial interstitial lung disease. N Engl J Med. 2001;344(8):573-579. (Pubitemid 32167871)
    • (2001) New England Journal of Medicine , vol.344 , Issue.8 , pp. 573-579
    • Nogee, L.M.1    Dunbar, A.E.2    Wert, S.E.3    Askin, F.4    Hamvas, A.5    Whitsett, J.A.6
  • 45
    • 76749165460 scopus 로고    scopus 로고
    • Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis
    • Sisson TH, et al. Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis. Am J Respir Crit Care Med. 2010;181(3):254-263.
    • (2010) Am J Respir Crit Care Med , vol.181 , Issue.3 , pp. 254-263
    • Sisson, T.H.1
  • 46
    • 54049115076 scopus 로고    scopus 로고
    • Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis
    • Korfei M, et al. Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2008;178(8):838-846.
    • (2008) Am J Respir Crit Care Med , vol.178 , Issue.8 , pp. 838-846
    • Korfei, M.1
  • 47
    • 48949119341 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: Association with altered surfactant protein processing and herpesvirus infection
    • Lawson WE, et al. Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection. Am J Physiol Lung Cell Mol Physiol. 2008;294(6):L1119-L1126.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294 , Issue.6
    • Lawson, W.E.1
  • 48
    • 77954589474 scopus 로고    scopus 로고
    • Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress
    • Maitra M, Wang Y, Gerard RD, Mendelson CR, Garcia CK. Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress. J Biol Chem. 2010;285(29):22103-22113.
    • (2010) J Biol Chem , vol.285 , Issue.29 , pp. 22103-22113
    • Maitra, M.1    Wang, Y.2    Gerard, R.D.3    Mendelson, C.R.4    Garcia, C.K.5
  • 50
    • 20044378690 scopus 로고    scopus 로고
    • A surfactant protein C precursor protein BRICHOS domain mutation causes endoplasmic reticulum stress, proteasome dysfunction, and caspase 3 activation
    • DOI 10.1165/rcmb.2005-0009OC
    • Mulugeta S, Nguyen V, Russo SJ, Muniswamy M, Beers MF. A surfactant protein C precursor protein BRICHOS domain mutation causes endoplasmic reticulum stress, proteasome dysfunction, and caspase 3 activation. Am J Respir Cell Mol Biol. 2005;32(6):521-530. (Pubitemid 40770130)
    • (2005) American Journal of Respiratory Cell and Molecular Biology , vol.32 , Issue.6 , pp. 521-530
    • Mulugeta, S.1    Nguyen, V.2    Russo, S.J.3    Muniswamy, M.4    Beers, M.F.5
  • 51
    • 72549115279 scopus 로고    scopus 로고
    • Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: The role of Nrf2-regulated proteasomal activity
    • Malhotra D, et al. Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity. Am J Respir Crit Care Med. 2009;180(12):1196-1207.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.12 , pp. 1196-1207
    • Malhotra, D.1
  • 54
    • 55849148482 scopus 로고    scopus 로고
    • The cytokine network in asthma and chronic obstructive pulmonary disease
    • Barnes PJ. The cytokine network in asthma and chronic obstructive pulmonary disease. J Clin Invest. 2008;118(11):3546-3556.
    • (2008) J Clin Invest , vol.118 , Issue.11 , pp. 3546-3556
    • Barnes, P.J.1
  • 56
    • 0032437815 scopus 로고    scopus 로고
    • Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung
    • Uhal BD, Joshi I, Hughes WF, Ramos C, Pardo A, Selman M. Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung. Am J Physiol. 1998;275(6 pt 1):L1192-L1199.
    • (1998) Am J Physiol , vol.275 , Issue.6 PART 1
    • Uhal, B.D.1    Joshi, I.2    Hughes, W.F.3    Ramos, C.4    Pardo, A.5    Selman, M.6
  • 57
    • 0035141395 scopus 로고    scopus 로고
    • Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP)
    • DOI 10.1136/jcp.54.2.132
    • Barbas-Filho JV, Ferreira MA, Sesso A, Kairalla RA, Carvalho CR, Capelozzi VL. Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP). J Clin Pathol. 2001;54(2):132-138. (Pubitemid 32128415)
    • (2001) Journal of Clinical Pathology , vol.54 , Issue.2 , pp. 132-138
    • Barbas-Filho, J.V.1    Ferreira, M.A.2    Sesso, A.3    Kairalla, R.A.4    Carvalho, C.R.R.5    Capelozzi, V.L.6
  • 58
    • 0033660171 scopus 로고    scopus 로고
    • Inhibition of VEGF receptors causes lung cell apoptosis and emphysema
    • Kasahara Y, et al. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J Clin Invest. 2000;106(11):1311-1319.
    • (2000) J Clin Invest , vol.106 , Issue.11 , pp. 1311-1319
    • Kasahara, Y.1
  • 59
    • 0034128473 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor receptors causes emphysema in rats
    • Tuder RM, Kasahara Y, Voelkel NF. Inhibition of vascular endothelial growth factor receptors causes emphysema in rats. Chest. 2000;117(5 suppl 1):281S.
    • (2000) Chest , vol.117 , Issue.5 SUPPL. 1
    • Tuder, R.M.1    Kasahara, Y.2    Voelkel, N.F.3
  • 60
    • 3442886811 scopus 로고    scopus 로고
    • The pathophysiology of mitochondrial cell death
    • DOI 10.1126/science.1099320
    • Green DR, Kroemer G. The pathophysiology of mitochondrial cell death. Science. 2004;305(5684):626-629. (Pubitemid 39006738)
    • (2004) Science , vol.305 , Issue.5684 , pp. 626-629
    • Green, D.R.1    Kroemer, G.2
  • 61
    • 77956095537 scopus 로고    scopus 로고
    • Mitochondria and cell death: Outer membrane permeabilization and beyond
    • Tait SW, Green DR. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol. 2010;11(9):621-632.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , Issue.9 , pp. 621-632
    • Tait, S.W.1    Green, D.R.2
  • 62
    • 26444442450 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: Cell life and death decisions
    • DOI 10.1172/JCI26373
    • Xu C, Bailly-Maitre B, Reed JC. Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest. 2005;115(10):2656-2664. (Pubitemid 41434389)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.10 , pp. 2656-2664
    • Xu, C.1    Bailly-Maitre, B.2    Reed, J.C.3
  • 63
    • 0016742681 scopus 로고
    • Derivation of type 1 epithelium from type 2 cells in the developing rat lung
    • Adamson IY, Bowden DH. Derivation of type 1 epithelium from type 2 cells in the developing rat lung. Lab Invest. 1975;32(6):736-745.
    • (1975) Lab Invest , vol.32 , Issue.6 , pp. 736-745
    • Adamson, I.Y.1    Bowden, D.H.2
  • 65
    • 66049083441 scopus 로고    scopus 로고
    • The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium
    • Rawlins EL, et al. The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium. Cell Stem Cell. 2009;4(6):525-534.
    • (2009) Cell Stem Cell , vol.4 , Issue.6 , pp. 525-534
    • Rawlins, E.L.1
  • 67
    • 0034974148 scopus 로고    scopus 로고
    • Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion
    • Hong KU, Reynolds SD, Giangreco A, Hurley CM, Stripp BR. Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion. Am J Respir Cell Mol Biol. 2001;24(6):671-681. (Pubitemid 32550588)
    • (2001) American Journal of Respiratory Cell and Molecular Biology , vol.24 , Issue.6 , pp. 671-681
    • Hong, K.U.1    Reynolds, S.D.2    Giangreco, A.3    Hurley, C.M.4    Stripp, B.R.5
  • 70
    • 77949531110 scopus 로고    scopus 로고
    • Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells
    • Tompkins DH, et al. Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells. PLoS One. 2009;4(12):e8248.
    • (2009) PLoS One , vol.4 , Issue.12
    • Tompkins, D.H.1
  • 72
    • 74949121801 scopus 로고    scopus 로고
    • Matrix modulation of compensatory lung regrowth and progenitor cell proliferation in mice
    • Hoffman AM, et al. Matrix modulation of compensatory lung regrowth and progenitor cell proliferation in mice. Am J Physiol Lung Cell Mol Physiol. 2010;298(2):L158-L168.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298 , Issue.2
    • Hoffman, A.M.1
  • 73
    • 48949119352 scopus 로고    scopus 로고
    • Cellular kinetics and modeling of bronchioalveolar stem cell response during lung regeneration
    • Nolen-Walston RD, et al. Cellular kinetics and modeling of bronchioalveolar stem cell response during lung regeneration. Am J Physiol Lung Cell Mol Physiol. 2008;294(6):L1158-L1165.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294 , Issue.6
    • Nolen-Walston, R.D.1
  • 76
    • 0035008101 scopus 로고    scopus 로고
    • Retinoic acid enhances lung growth after pneumonectomy
    • Kaza AK, et al. Retinoic acid enhances lung growth after pneumonectomy. Ann Thorac Surg. 2001;71(5):1645-1650.
    • (2001) Ann Thorac Surg , vol.71 , Issue.5 , pp. 1645-1650
    • Kaza, A.K.1
  • 77
    • 0033736556 scopus 로고    scopus 로고
    • Epidermal growth factor augments postpneumonectomy lung growth
    • Kaza AK, et al. Epidermal growth factor augments postpneumonectomy lung growth. J Thorac Cardiovasc Surg. 2000;120(5):916-921.
    • (2000) J Thorac Cardiovasc Surg , vol.120 , Issue.5 , pp. 916-921
    • Kaza, A.K.1
  • 79
    • 0037213389 scopus 로고    scopus 로고
    • The role of hepatocytes and oval cells in liver regeneration and repopulation
    • DOI 10.1016/S0925-4773(02)00338-6, PII S0925477302003386
    • Fausto N, Campbell JS. The role of hepatocytes and oval cells in liver regeneration and repopulation. Mech Dev. 2003;120(1):117-130. (Pubitemid 35462100)
    • (2003) Mechanisms of Development , vol.120 , Issue.1 , pp. 117-130
    • Fausto, N.1    Campbell, J.S.2
  • 80
    • 47949120382 scopus 로고    scopus 로고
    • Conditional stabilization of beta-catenin expands the pool of lung stem cells
    • Reynolds SD, et al. Conditional stabilization of beta-catenin expands the pool of lung stem cells. Stem Cells. 2008;26(5):1337-1346.
    • (2008) Stem Cells , vol.26 , Issue.5 , pp. 1337-1346
    • Reynolds, S.D.1
  • 81
    • 70349862613 scopus 로고    scopus 로고
    • Beta-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium
    • Zemke AC, et al. beta-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium. Am J Respir Cell Mol Biol. 2009;41(5):535-543.
    • (2009) Am J Respir Cell Mol Biol , vol.41 , Issue.5 , pp. 535-543
    • Zemke, A.C.1
  • 82
    • 77956288500 scopus 로고    scopus 로고
    • Inhibition of Wnt/betacatenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
    • Henderson WR Jr, et al. Inhibition of Wnt/betacatenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis. Proc Natl Acad Sci U S A. 2010;107(32):14309-14314.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.32 , pp. 14309-14314
    • Henderson Jr., W.R.1
  • 84
    • 47749101725 scopus 로고    scopus 로고
    • Functional Wnt signaling is increased in idiopathic pulmonary fibrosis
    • Konigshoff M, et al. Functional Wnt signaling is increased in idiopathic pulmonary fibrosis. PLoS One. 2008;3(5):e2142.
    • (2008) PLoS One , vol.3 , Issue.5
    • Konigshoff, M.1
  • 85
    • 77955115175 scopus 로고    scopus 로고
    • Tissue-engineered lungs for in vivo implantation
    • Petersen TH, et al. Tissue-engineered lungs for in vivo implantation. Science. 2010;329(5991):538-541.
    • (2010) Science , vol.329 , Issue.5991 , pp. 538-541
    • Petersen, T.H.1
  • 86
    • 36248966518 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
    • DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
    • Takahashi K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131(5):861-872. (Pubitemid 350138099)
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 87
    • 35148845584 scopus 로고    scopus 로고
    • Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
    • DOI 10.1038/nbt1335, PII NBT1335
    • Meissner A, Wernig M, Jaenisch R. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat Biotechnol. 2007;25(10):1177-1181. (Pubitemid 47538112)
    • (2007) Nature Biotechnology , vol.25 , Issue.10 , pp. 1177-1181
    • Meissner, A.1    Wernig, M.2    Jaenisch, R.3
  • 88
    • 33747195353 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126(4):663-676. (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2


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