Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase

American Journal of Respiratory Cell and Molecular Biology

Volumn 54, Issue 3, 2016, Pages 341-349

  Garratt, Luke W ^a,b   Sutanto, Erika N ^b,c   Ling, Kak Ming ^b   Looi, Kevin ^a   Iosifidis, Thomas ^a,d   Martinovich, Kelly M ^b   Shaw, Nicole C ^b   Buckley, Alysia G ^b,e   Kicic Starcevich, Elizabeth ^b,c   Lannigan, Francis J ^a,f   Knight, Darryl A ^g,h,i   Stick, Stephen M ^a,b,c,d   Kicic, Anthony ^a,b,c,d  

^a School of Paediatrics and Child Health   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c PRINCESS MARGARET HOSPITAL FOR CHILDREN   (Australia)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^f UNIVERSITY OF NOTRE DAME   (Australia)

^g UNIVERSITY OF NEWCASTLE   (Australia)

^h Centre for Asthma and Respiratory Diseases   (Australia)

ⁱ UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Alpha 1 antitrypsin; Cystic fibrosis; Neutrophil elastase; Primary cell culture; Wound repair

Indexed keywords

ALPHA 1 ANTITRYPSIN; CYTOKINE; LEUKOCYTE ELASTASE; PROTEINASE; PROTEINASE INHIBITOR; AUTACOID; SERPINA1 PROTEIN, HUMAN;

ADOLESCENT; APOPTOSIS; ARTICLE; CELL CULTURE; CELL METABOLISM; CELL PROLIFERATION; CELL VIABILITY; CHILD; CONTROLLED STUDY; CYSTIC FIBROSIS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EFFECT; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; MAJOR CLINICAL STUDY; PHENOTYPE; PRESCHOOL CHILD; RESPIRATORY EPITHELIUM; WOUND HEALING; CASE CONTROL STUDY; CELL ADHESION; CELL MOTION; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; FEMALE; INFANT; MALE; METABOLISM; NEWBORN; PATHOLOGY; REGENERATION; RESPIRATORY TRACT MUCOSA; TIME FACTOR;

ALPHA 1-ANTITRYPSIN; APOPTOSIS; CASE-CONTROL STUDIES; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CYSTIC FIBROSIS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; INFLAMMATION MEDIATORS; LEUKOCYTE ELASTASE; MALE; PHENOTYPE; REGENERATION; RESPIRATORY MUCOSA; TIME FACTORS;

EID: 84963851413     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2015-0074OC     Document Type: Article

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