The resveratrol trimer miyabenol C inhibits β-secretase activity and β-amyloid generation

PLoS ONE

Volumn 10, Issue 1, 2015, Pages

  Hu, Jin ^a   Lin, Ting ^a   Gao, Yuehong ^a   Xu, Junyue ^a   Jiang, Chao ^a   Wang, Guanghui ^a   Bu, Guojun ^a   Xu, Huaxi ^a   Chen, Haifeng ^a   Zhang, Yun Wu ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM10 ENDOPEPTIDASE; ALPHA SECRETASE; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SECRETASE 1; BETA SECRETASE INHIBITOR; GAMMA SECRETASE; MIYABENOL C; NOTCH RECEPTOR; PRESENILIN 1; RESVERATROL; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; BENZOFURAN DERIVATIVE; PLANT EXTRACT; SECRETASE; STILBENE DERIVATIVE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; HIPPOCAMPUS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; CHEMISTRY; DRUG EFFECTS; ENZYME ACTIVATION; METABOLISM; PATHOLOGY; PROTEIN DEGRADATION; SOLUBILITY; TRANSGENIC MOUSE; TUMOR CELL LINE;

MUS; VITACEAE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BENZOFURANS; BRAIN; CELL LINE, TUMOR; ENZYME ACTIVATION; HUMANS; MICE; MICE, TRANSGENIC; PLANT EXTRACTS; PROTEOLYSIS; SOLUBILITY; STILBENES;

EID: 84961291056     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115973     Document Type: Article

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