Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin

eLife

Volumn 5, Issue FEBRUARY2016, 2016, Pages

  Bae, Chanhyung ^a,b   Anselmi, Claudio ^c   Kalia, Jeet ^a,d   Jara Oseguera, Andres ^a   Schwieters, Charles D ^c   Krepkiy, Dmitriy ^a   Lee, Chul Won ^e   Kim, Eun Hee ^f   Kim, Jae I I ^b   Faraldo Gómez, José D ^c   Swartz, Kenton J ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b Gwangju Institute of Science and Technology (GIST)   (South Korea)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH   (India)

^e Chonnam National University   (South Korea)

^f Korea Basic Science Institute (KBSI)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

SPIDER VENOM; TARANTULA TOXIN; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; PROTEIN BINDING; TRPV1 PROTEIN, RAT; VANILLOID RECEPTOR;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BILAYER MEMBRANE; CHEMICAL BINDING; COMPUTER INTERFACE; ELECTRODE; ENERGY FILTERED TRANSMISSION ELECTRON MICROSCOPY; GENE ACTIVATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; LIPID BILAYER; MOLECULAR DOCKING; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; VOLTAGE CLAMP TECHNIQUE; WHOLE CELL PATCH CLAMP; CELL MEMBRANE; CHEMISTRY; METABOLISM;

CELL MEMBRANE; PROTEIN BINDING; SPIDER VENOMS; TRPV CATION CHANNELS;

EID: 84961285113     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.11273     Document Type: Article

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