Interaction of acid-sensing ion channel (ASIC) 1 with the tarantula toxin psalmotoxin 1 is state dependent

Journal of General Physiology

Volumn 127, Issue 3, 2006, Pages 267-276

  Chen, Xuanmao ^a   Kalbacher, Hubert ^b   Gründer, Stefan ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACID SENSING ION CHANNEL 1; PROTEIN SUBUNIT; PROTON; PSALMOTOXIN 1; SODIUM CHANNEL; SPIDER VENOM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHANNEL GATING; CONTROLLED STUDY; DESENSITIZATION; NONHUMAN; PROTEIN BINDING;

ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; OOCYTES; PROTEIN BINDING; RATS; SODIUM; SODIUM CHANNELS; SPIDER VENOMS; XENOPUS LAEVIS;

EID: 33644596215     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200509409     Document Type: Article

References (37)

1. Babini, E., M. Paukert, H.S. Geisler, and S. Gründer. 2002. Alternative splicing and interaction with di- and polyvalent cations control the dynamic range of acid-sensing ion channel 1 (ASIC1). J. Biol. Chem. 277:41597-41603.
2. Balser, J.R., H.B. Nuss, D.W. Orias, D.C. Johns, E. Marban, G.F. Tomaselli, and J.H. Lawrence. 1996. Local anesthetics as effectors of allosteric gating. Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels. J. Clin. Invest. 98:2874-2886.
3. Baron, A., R. Waldmann, and M. Lazdunski. 2002. ASIC-like, proton-activated currents in rat hippocampal neurons. J. Physiol. 539:485-494.
4. Bean, B.P. 1984. Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state. Proc. Natl. Acad. Sci. USA. 81:6388-6392.
5. +-gated channels in mouse sensory neurons. Proc. Natl. Acad. Sci. USA. 99:2338-2343.
6. Bässler, E.L., T.J. Ngo-Anh, H.S. Geisler, J.P. Ruppersberg, and S. Gründer. 2001. Molecular and functional characterization of acid-sensing ion channel (ASIC) 1b. J. Biol. Chem. 276:33782-33787.
7. Chen, C.C., S. England, A.N. Akopian, and J.N. Wood. 1998. A sensory neuron-specific, proton-gated ion channel. Proc. Natl. Acad. Sci. USA. 95:10240-10245.
8. Chen, C.C., A. Zimmer, W.H. Sun, J. Hall, and M.J. Brownstein. 2002. A role for ASIC3 in the modulation of high-intensity pain stimuli. Proc. Natl. Acad. Sci. USA. 99:8992-8997.
9. + affinity. J. Gen. Physiol. 126:71-79.
10. Colquhoun, D. 1998. Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. Br. J. Pharmacol. 125:924-947.
11. + channels. J. Biol. Chem. 275:25116-25121.
12. Escoubas, P., C. Bernard, G. Lambeau, M. Lazdunski, and H. Darbon. 2003. Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels. Protein Sci. 12:1332-1343.
13. Hess, P., J.B. Lansman, and R.W. Tsien. 1984. Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature. 311:538-544.
14. Hille, B. 1977. Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. J. Gen. Physiol. 69:497-515.
15. 2+ blockade. Neuron. 37:75-84.
16. Kass, R.S., and D.S. Krafte. 1987. Negative surface charge density near heart calcium channels. Relevance to block by dihydropyridines. J. Gen. Physiol. 89:629-644.
17. Krishtal, O. 2003. The ASICs: signaling molecules? Modulators? Trends Neurosci. 26:477-483.
18. Madeja, M., U. Musshoff, and E.J. Speckmann. 1995. Improvement and testing of a concentration-clamp system for oocytes of Xenopus laevis. J. Neurosci. Methods. 63:211-213.
19. Mamet, J., A. Baron, M. Lazdunski, and N. Voilley. 2002. Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels. J. Neurosci. 22:10662-10670.
20. Marks, T.N., and S.W. Jones. 1992. Calcium currents in the A7r5 smooth muscle-derived cell line. An allosteric model for calcium channel activation and dihydropyridine agonist action. J. Gen. Physiol. 99:367-390.
21. Monod, J., J. Wyman, and J.P. Changeux. 1965. On the nature of allosteric transitions: a plausible model. J. Mol. Biol. 12:88-118.
22. Paukert, M., S. Sidi, C. Russell, M. Siba, S.W. Wilson, T. Nicolson, and S. Gründer. 2004. A family of acid-sensing ion channels from the zebrafish: widespread expression in the central nervous system suggests a conserved role in neuronal communication. J. Biol. Chem. 279:18783-18791.
23. Phillips, L.R., M. Milescu, Y. Li-Smerin, J.A. Mindell, J.I. Kim, and K.J. Swartz. 2005. Voltage-sensor activation with a tarantula toxin as cargo. Nature. 436:857-860.
24. Price, M.P., G.R. Lewin, S.L. McIlwrath, C. Cheng, J. Xie, P.A. Heppenstall, C.L. Stucky, A.G. Mannsfeldt, T.J. Brennan, H.A. Drummond, et al. 2000. The mammalian sodium channel BNC1 is required for normal touch sensation. Nature. 407:1007-1011.
25. Pusch, M., A. Accardi, A. Liantonio, L. Ferrera, A. De Luca, D.C. Camerino, and F. Conti. 2001. Mechanism of block of single protopores of the Torpedo chloride channel ClC-0 by 2-(p-chlorophenoxy) butyric acid (CPB). J. Gen. Physiol. 118:45-62.
26. Salinas, M., L.D. Rash, A. Baron, G. Lambeau, P. Escoubas, and M. Lazdunski. 2006. The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a. J. Physiol. 570:339-354.
27. Sanguinetti, M.C., D.S. Krafte, and R.S. Kass. 1986. Voltage-dependent modulation of Ca channel current in heart cells by Bay K8644. J. Gen. Physiol. 88:369-392.
28. Saugstad, J.A., J.A. Roberts, J. Dong, S. Zeitouni, and R.J. Evans. 2004. Analysis of the membrane topology of the acid-sensing ion channel 2a. J. Biol. Chem. 279:55514-55519.
29. Sutherland, S.P., C.J. Benson, J.P. Adelman, and E.W. McCleskey. 2001. Acid-sensing ion channel 3 matches the acid-gated current in cardiac ischemia-sensing neurons. Proc. Natl. Acad. Sci. USA. 98:711-716.
30. + channel through multiple binding sites. Neuron. 18:665-673.
31. Ugawa, S., T. Yamamoto, T. Ueda, Y. Ishida, A. Inagaki, M. Nishigaki, S. Shimada, Y. Minami, W. Guo, Y. Saishin, et al. 2003. Amiloride-insensitive currents of the acid-sensing ion channel-2a (ASIC2a)/ ASIC2b heteromeric sour-taste receptor channel. J. Neurosci. 23:3616-3622.
32. Voilley, N., J. de Weille, J. Mamet, and M. Lazdunski. 2001. Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors. J. Neurosci. 21:8026-8033.
33. +-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels. Curr. Opin. Neurobiol. 8:418-424.
34. + channel specific for sensory neurons. J. Biol. Chem. 272:20975-20978.
35. Wemmie, J.A., J. Chen, C.C. Askwith, A.M. Hruska-Hageman, M.P. Price, B.C. Nolan, P.G. Yoder, E. Lamani, T. Hoshi, J.H. Freeman Jr., and M.J. Welsh. 2002. The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory. Neuron. 34:463-477.
36. Wemmie, J.A., C.C. Askwith, E. Lamani, M.D. Cassell, J.H. Freeman Jr., M.J. Welsh, A.S. Leonard, O. Yermolaieva, A. Hruska-Hageman, M.P. Price, et al. 2003. Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning. J. Neurosci. 23:5496-5502.
37. Xie, J., M.P. Price, A.L. Berger, and M.J. Welsh. 2002. DRASIC contributes to pH-gated currents in large dorsal root ganglion sensory neurons by forming heteromultimeric channels. J. Neurophysiol. 87:2835-2843.