High Yield Production and Refolding of the Double-Knot Toxin, an Activator of TRPV1 Channels

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Bae, Chanhyung ^a   Kalia, Jeet ^b   Song, Inhye ^a   Yu, JeongHeon ^a   Kim, Ha Hyung ^c   Swartz, Kenton J ^b   Kim, Jae Il ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c Chung Ang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE KNOT TOXIN; SPIDER VENOM; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHANNEL GATING; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; EQUILIBRIUM CONSTANT; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; OXIDATIVE STRESS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN ISOLATION; PROTEIN PURIFICATION; PROTEIN REFOLDING; PROTEIN SECONDARY STRUCTURE; STRUCTURE ACTIVITY RELATION; TOXIN ANALYSIS; TOXIN STRUCTURE; TOXIN SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CYSTEINE; KINETICS; MOLECULAR SEQUENCE DATA; OOCYTES; PEPTIDES; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; SPIDER VENOMS; SPIDERS; TRPV CATION CHANNELS; XENOPUS LAEVIS; XENOPUS PROTEINS;

ORNITHOCTONUS HUWENA; TARANTULA;

EID: 84871166454     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051516     Document Type: Article

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