-
1
-
-
0029989851
-
The signature sequence of voltage-gated potassium channels projects into the external vestibule
-
doi: 10.1074/jbc.271.49.31013
-
Aiyar J, Rizzi JP, Gutman GA, Chandy KG. 1996. The signature sequence of voltage-gated potassium channels projects into the external vestibule. J Biol Chem 271:31013-6. doi: 10.1074/jbc.271.49.31013.
-
(1996)
J Biol Chem
, vol.271
, pp. 31013-31016
-
-
Aiyar, J.1
Rizzi, J.P.2
Gutman, G.A.3
Chandy, K.G.4
-
2
-
-
0028835235
-
Topology of the pore-region of a K+ channel revealed by the NMR-derived structures of scorpion toxins
-
doi: 10.1016/0896-6273(95)90104-3
-
Aiyar J, Withka JM, Rizzi JP, Singleton DH, Andrews GC, Lin W, et al. 1995. Topology of the pore-region of a K+ channel revealed by the NMR-derived structures of scorpion toxins. Neuron 15:1169-81. doi: 10.1016/0896-6273(95)90104-3.
-
(1995)
Neuron
, vol.15
, pp. 1169-1181
-
-
Aiyar, J.1
Withka, J.M.2
Rizzi, J.P.3
Singleton, D.H.4
Andrews, G.C.5
Lin, W.6
-
3
-
-
36248946187
-
Portability of paddle motif function and pharmacology in voltage sensors
-
doi: 10.1038/nature06266
-
Alabi AA, Bahamonde MI, Jung HJ, Kim JI, Swartz KJ. 2007. Portability of paddle motif function and pharmacology in voltage sensors. Nature 450:370-5. doi: 10.1038/nature06266.
-
(2007)
Nature
, vol.450
, pp. 370-375
-
-
Alabi, A.A.1
Bahamonde, M.I.2
Jung, H.J.3
Kim, J.I.4
Swartz, K.J.5
-
4
-
-
0023907940
-
Charybdotoxin block of single Ca2+-activated K+ channels. Effects of channel gating, voltage, and ionic strength
-
doi: 10.1085/jgp.91.3.317
-
Anderson CS, MacKinnon R, Smith C, Miller C. 1988. Charybdotoxin block of single Ca2+-activated K+ channels. Effects of channel gating, voltage, and ionic strength. J Gen Physiol 91:317-33. doi: 10.1085/jgp.91.3.317.
-
(1988)
J Gen Physiol
, vol.91
, pp. 317-333
-
-
Anderson, C.S.1
McKinnon, R.2
Smith, C.3
Miller, C.4
-
5
-
-
52949131528
-
Animal peptides targeting voltage-activated sodium channels
-
doi: 10.2174/138161208785777423
-
Billen B, Bosmans F, Tytgat J. 2008. Animal peptides targeting voltage-activated sodium channels. Curr Pharm Des 14:2492-502. doi: 10.2174/138161208785777423.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 2492-2502
-
-
Billen, B.1
Bosmans, F.2
Tytgat, J.3
-
6
-
-
0026418431
-
Refined structure of charybdotoxin: Common motifs in scorpion toxins and insect defensins
-
doi: 10.1126/science.1720574
-
Bontems F, Roumestand C, Gilquin B, Menez A, Toma F. 1991. Refined structure of charybdotoxin: common motifs in scorpion toxins and insect defensins. Science 254:1521-3. doi: 10.1126/science.1720574.
-
(1991)
Science
, vol.254
, pp. 1521-1523
-
-
Bontems, F.1
Roumestand, C.2
Gilquin, B.3
Menez, A.4
Toma, F.5
-
7
-
-
37049014272
-
Version 1.2 of the crystallography and NMR system
-
doi: 10.1038/nprot.2007.406
-
Brunger AT. 2007. Version 1.2 of the crystallography and NMR system. Nat Protoc 2:2728-33. doi: 10.1038/nprot.2007.406.
-
(2007)
Nat Protoc
, vol.2
, pp. 2728-2733
-
-
Brunger, A.T.1
-
8
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
doi: 10.1107/S0907444998003254
-
Brunger AT, Adams PD, Clore GM, Delano WL, Gros P, Grosse-Kunstleve RW, et al. 1998. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr 54:905-21. doi: 10.1107/S0907444998003254.
-
(1998)
Acta Crystallogr D Biol Crystallogr
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
Delano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
-
9
-
-
0020026499
-
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin
-
doi: 10.1038/296090a0
-
Carbone E, Wanke E, Prestipino G, Possani LD, Maelicke A. 1982. Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin. Nature 296:90-1. doi: 10.1038/296090a0.
-
(1982)
Nature
, vol.296
, pp. 90-91
-
-
Carbone, E.1
Wanke, E.2
Prestipino, G.3
Possani, L.D.4
Maelicke, A.5
-
10
-
-
0029572430
-
Determination of the three-dimensional solution structure of noxiustoxin: Analysis of structural differences with related short-chain scorpion toxins
-
doi: 10.1021/bi00051a004
-
Dauplais M, Gilquin B, Possani LD, Gurrola-Briones G, Roumestand C, Menez A. 1995. Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins. Biochemistry 34:16563-73. doi: 10.1021/bi00051a004.
-
(1995)
Biochemistry
, vol.34
, pp. 16563-16573
-
-
Dauplais, M.1
Gilquin, B.2
Possani, L.D.3
Gurrola-Briones, G.4
Roumestand, C.5
Menez, A.6
-
11
-
-
0030841590
-
Collaborative computational project, number 4: Providing programs for protein crystallography
-
doi: 10.1016/S0076-6879(97)77034-4
-
Dodson EJ, Winn M, Ralph A. 1997. Collaborative computational project, number 4: providing programs for protein crystallography. Methods Enzymol 277:620-33. doi: 10.1016/S0076-6879(97)77034-4.
-
(1997)
Methods Enzymol
, vol.277
, pp. 620-633
-
-
Dodson, E.J.1
Winn, M.2
Ralph, A.3
-
12
-
-
0032478818
-
The structure of the potassium channel: Molecular basis of K+ conduction and selectivity
-
doi: 10.1126/science.280.5360.69
-
Doyle DA, Morais Cabral J, Pfuetzner RA, Kuo A, Gulbis JM, Cohen SL, et al. 1998. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science 280:69-77. doi: 10.1126/science.280.5360.69.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Morais Cabral, J.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
-
13
-
-
13244281317
-
Coot: Model-building tools for molecular graphics
-
doi: 10.1107/S0907444904019158
-
Emsley P, Cowtan K. 2004. Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr 60:2126-32. doi: 10.1107/S0907444904019158.
-
(2004)
Acta Crystallogr D Biol Crystallogr
, vol.60
, pp. 2126-2132
-
-
Emsley, P.1
Cowtan, K.2
-
14
-
-
0028138407
-
Kaliotoxin (1-37) shows structural differences with related potassium channel blockers
-
doi: 10.1021/bi00251a038
-
Fernandez I, Romi R, Szendeffy S, Martin-Eauclaire MF, Rochat H, van Rietschoten J, et al. 1994. Kaliotoxin (1-37) shows structural differences with related potassium channel blockers. Biochemistry 33:14256-63. doi: 10.1021/bi00251a038.
-
(1994)
Biochemistry
, vol.33
, pp. 14256-14263
-
-
Fernandez, I.1
Romi, R.2
Szendeffy, S.3
Martin-Eauclaire, M.F.4
Rochat, H.5
van Rietschoten, J.6
-
15
-
-
0025299607
-
Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus
-
Galvez A, Gimenez-Gallego G, Reuben JP, Roy-Contancin L, Feigenbaum P, Kaczorowski GJ, et al. 1990. Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus. J Biol Chem 265:11083-90.
-
(1990)
J Biol Chem
, vol.265
, pp. 11083-11090
-
-
Galvez, A.1
Gimenez-Gallego, G.2
Reuben, J.P.3
Roy-Contancin, L.4
Feigenbaum, P.5
Kaczorowski, G.J.6
-
16
-
-
0028335105
-
Purification and characterization of three inhibitors of voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom
-
doi: 10.1021/bi00188a012
-
Garcia ML, Garcia-Calvo M, Hidalgo P, Lee A, MacKinnon R. 1994. Purification and characterization of three inhibitors of voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom. Biochemistry 33:6834-9. doi: 10.1021/bi00188a012.
-
(1994)
Biochemistry
, vol.33
, pp. 6834-6839
-
-
Garcia, M.L.1
Garcia-Calvo, M.2
Hidalgo, P.3
Lee, A.4
McKinnon, R.5
-
17
-
-
0030629190
-
Pharmacology of potassium channels
-
doi: 10.1016/S1054-3589(08)60078-2
-
Garcia ML, Hanner M, Knaus HG, Koch R, Schmalhofer W, Slaughter RS, et al. 1997. Pharmacology of potassium channels. Adv Pharmacol 39:425-71. doi: 10.1016/S1054-3589(08)60078-2.
-
(1997)
Adv Pharmacol
, vol.39
, pp. 425-471
-
-
Garcia, M.L.1
Hanner, M.2
Knaus, H.G.3
Koch, R.4
Schmalhofer, W.5
Slaughter, R.S.6
-
18
-
-
0026773747
-
A point mutation in a Shaker K+ channel changes its charybdotoxin binding site from low to high affinity
-
doi: 10.1016/S0006-3495(92)81760-5
-
Goldstein SA, Miller C. 1992. A point mutation in a Shaker K+ channel changes its charybdotoxin binding site from low to high affinity. Biophys J 62:5-7. doi: 10.1016/S0006-3495(92)81760-5.
-
(1992)
Biophys J
, vol.62
, pp. 5-7
-
-
Goldstein, S.A.1
Miller, C.2
-
19
-
-
0027443836
-
Mechanism of charybdotoxin block of a voltage-gated K+ channel
-
doi: 10.1016/S0006-3495(93)81200-1
-
Goldstein SA, Miller C. 1993. Mechanism of charybdotoxin block of a voltage-gated K+ channel. Biophys J 65:1613-9. doi: 10.1016/S0006-3495(93)81200-1.
-
(1993)
Biophys J
, vol.65
, pp. 1613-1619
-
-
Goldstein, S.A.1
Miller, C.2
-
20
-
-
0028276482
-
The charybdotoxin receptor of a Shaker K+ channel: Peptide and channel residues mediating molecular recognition
-
doi: 10.1016/0896-6273(94)90452-9
-
Goldstein SA, Pheasant DJ, Miller C. 1994. The charybdotoxin receptor of a Shaker K+ channel: peptide and channel residues mediating molecular recognition. Neuron 12:1377-88. doi: 10.1016/0896-6273(94)90452-9.
-
(1994)
Neuron
, vol.12
, pp. 1377-1388
-
-
Goldstein, S.A.1
Pheasant, D.J.2
Miller, C.3
-
21
-
-
0028105127
-
Transfer of the scorpion toxin receptor to an insensitive potassium channel
-
doi: 10.1016/0896-6273(94)90261-5
-
Gross A, Abramson T, MacKinnon R. 1994. Transfer of the scorpion toxin receptor to an insensitive potassium channel. Neuron 13:961-6. doi: 10.1016/0896-6273(94)90261-5.
-
(1994)
Neuron
, vol.13
, pp. 961-966
-
-
Gross, A.1
Abramson, T.2
McKinnon, R.3
-
22
-
-
0030051784
-
Agitoxin footprinting the shaker potassium channel pore
-
doi: 10.1016/S0896-6273(00)80057-4
-
Gross A, MacKinnon R. 1996. Agitoxin footprinting the shaker potassium channel pore. Neuron 16:399-406. doi: 10.1016/S0896-6273(00)80057-4.
-
(1996)
Neuron
, vol.16
, pp. 399-406
-
-
Gross, A.1
McKinnon, R.2
-
23
-
-
52949118506
-
Conus venoms-a rich source of peptide-based therapeutics
-
doi: 10.2174/138161208785777469
-
Han TS, Teichert RW, Olivera BM, Bulaj G. 2008. Conus venoms-a rich source of peptide-based therapeutics. Curr Pharm Des 14:2462-79. doi: 10.2174/138161208785777469.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 2462-2479
-
-
Han, T.S.1
Teichert, R.W.2
Olivera, B.M.3
Bulaj, G.4
-
24
-
-
0028987938
-
Revealing the architecture of a K+ channel pore through mutant cycles with a peptide inhibitor
-
doi: 10.1126/science.7716527
-
Hidalgo P, MacKinnon R. 1995. Revealing the architecture of a K+ channel pore through mutant cycles with a peptide inhibitor. Science 268:307-10. doi: 10.1126/science.7716527.
-
(1995)
Science
, vol.268
, pp. 307-310
-
-
Hidalgo, P.1
McKinnon, R.2
-
25
-
-
0038076054
-
X-ray structure of a voltage-dependent K+ channel
-
doi: 10.1038/nature01580
-
Jiang Y, Lee A, Chen J, Ruta V, Cadene M, Chait BT, et al. 2003. X-ray structure of a voltage-dependent K+ channel. Nature 423:33-41. doi: 10.1038/nature01580.
-
(2003)
Nature
, vol.423
, pp. 33-41
-
-
Jiang, Y.1
Lee, A.2
Chen, J.3
Ruta, V.4
Cadene, M.5
Chait, B.T.6
-
26
-
-
0026781766
-
Determination of the three-dimensional structure of iberiotoxin in solution by 1H nuclear magnetic resonance spectroscopy
-
doi: 10.1021/bi00150a006
-
Johnson BA, Sugg EE. 1992 Determination of the three-dimensional structure of iberiotoxin in solution by 1H nuclear magnetic resonance spectroscopy. Biochemistry 31:8151-9. doi: 10.1021/bi00150a006.
-
(1992)
Biochemistry
, vol.31
, pp. 8151-8159
-
-
Johnson, B.A.1
Sugg, E.E.2
-
27
-
-
69249097477
-
Naturally occurring and synthetic peptides acting on nicotinic acetylcholine receptors
-
doi: 10.2174/138161209788682316
-
Kasheverov IE, Utkin YN, Tsetlin VI. 2009. Naturally occurring and synthetic peptides acting on nicotinic acetylcholine receptors. Curr Pharm Des 15:2430-52. doi: 10.2174/138161209788682316.
-
(2009)
Curr Pharm Des
, vol.15
, pp. 2430-2452
-
-
Kasheverov, I.E.1
Utkin, Y.N.2
Tsetlin, V.I.3
-
28
-
-
49449095296
-
Peptide toxins that selectively target insect Na(V) and Ca(V) channels
-
doi: 10.4161/chan.2.2.6022
-
King GF, Escoubas P, Nicholson GM. 2008. Peptide toxins that selectively target insect Na(V) and Ca(V) channels. Channels 2:100-16. doi: 10.4161/chan.2.2.6022.
-
(2008)
Channels
, vol.2
, pp. 100-116
-
-
King, G.F.1
Escoubas, P.2
Nicholson, G.M.3
-
29
-
-
0029113242
-
Solution structure of the potassium channel inhibitor agitoxin 2: Caliper for probing channel geometry
-
doi: 10.1002/pro.5560040805
-
Krezel AM, Kasibhatla C, Hidalgo P, MacKinnon R, Wagner G. 1995. Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry. Protein Sci 4:1478-89. doi: 10.1002/pro.5560040805.
-
(1995)
Protein Sci
, vol.4
, pp. 1478-1489
-
-
Krezel, A.M.1
Kasibhatla, C.2
Hidalgo, P.3
McKinnon, R.4
Wagner, G.5
-
30
-
-
33645858263
-
Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR
-
doi: 10.1038/nature04649
-
Lange A, Giller K, Hornig S, Martin-Eauclaire MF, Pongs O, Becker S, et al. 2006. Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR. Nature 440:959-62. doi: 10.1038/nature04649.
-
(2006)
Nature
, vol.440
, pp. 959-962
-
-
Lange, A.1
Giller, K.2
Hornig, S.3
Martin-Eauclaire, M.F.4
Pongs, O.5
Becker, S.6
-
31
-
-
54349089601
-
Proteome and peptidome profiling of spider venoms
-
doi: 10.1586/14789450.5.5.731
-
Liang S. 2008. Proteome and peptidome profiling of spider venoms. Expert Rev Proteomics 5:731-46. doi: 10.1586/14789450.5.5.731.
-
(2008)
Expert Rev Proteomics
, vol.5
, pp. 731-746
-
-
Liang, S.1
-
32
-
-
36248982122
-
Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment
-
doi: 10.1038/nature06265
-
Long SB, Tao X, Campbell EB, MacKinnon R. 2007. Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment. Nature 450:376-82. doi: 10.1038/nature06265.
-
(2007)
Nature
, vol.450
, pp. 376-382
-
-
Long, S.B.1
Tao, X.2
Campbell, E.B.3
McKinnon, R.4
-
33
-
-
0025762715
-
Determination of the subunit stoichiometry of a voltage-activated potassium channel
-
doi: 10.1038/350232a0
-
MacKinnon R. 1991. Determination of the subunit stoichiometry of a voltage-activated potassium channel. Nature 350:232-5. doi: 10.1038/350232a0.
-
(1991)
Nature
, vol.350
, pp. 232-235
-
-
McKinnon, R.1
-
34
-
-
0032478696
-
Structural conservation in prokaryotic and eukaryotic potassium channels
-
doi: 10.1126/science.280.5360.106
-
MacKinnon R, Cohen SL, Kuo A, Lee A, Chait BT. 1998. Structural conservation in prokaryotic and eukaryotic potassium channels. Science 280:106-9. doi: 10.1126/science.280.5360.106.
-
(1998)
Science
, vol.280
, pp. 106-109
-
-
McKinnon, R.1
Cohen, S.L.2
Kuo, A.3
Lee, A.4
Chait, B.T.5
-
35
-
-
0025644364
-
Mapping the receptor site for charybdotoxin, a pore-blocking potassium channel inhibitor
-
doi: 10.1016/0896-6273(90)90335-D
-
MacKinnon R, Heginbotham L, Abramson T. 1990. Mapping the receptor site for charybdotoxin, a pore-blocking potassium channel inhibitor. Neuron 5:767-71. doi: 10.1016/0896-6273(90)90335-D.
-
(1990)
Neuron
, vol.5
, pp. 767-771
-
-
McKinnon, R.1
Heginbotham, L.2
Abramson, T.3
-
36
-
-
0023887273
-
Mechanism of charybdotoxin block of the high-conductance, Ca2+-activated K+ channel
-
doi: 10.1085/jgp.91.3.335
-
MacKinnon R, Miller C. 1988. Mechanism of charybdotoxin block of the high-conductance, Ca2+-activated K+ channel. J Gen Physiol 91:335-49. doi: 10.1085/jgp.91.3.335.
-
(1988)
J Gen Physiol
, vol.91
, pp. 335-349
-
-
McKinnon, R.1
Miller, C.2
-
37
-
-
0024426645
-
Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor
-
doi: 10.1126/science.2476850
-
MacKinnon R, Miller C. 1989. Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor. Science 245:1382-5. doi: 10.1126/science.2476850.
-
(1989)
Science
, vol.245
, pp. 1382-1385
-
-
McKinnon, R.1
Miller, C.2
-
38
-
-
0028983387
-
The charybdotoxin family of K+ channel-blocking peptides
-
doi: 10.1016/0896-6273(95)90057-8
-
Miller C. 1995. The charybdotoxin family of K+ channel-blocking peptides. Neuron 15:5-10. doi: 10.1016/0896-6273(95)90057-8.
-
(1995)
Neuron
, vol.15
, pp. 5-10
-
-
Miller, C.1
-
39
-
-
0021918550
-
Charybdotoxin, a protein inhibitor of single Ca2+-activated K+ channels from mammalian skeletal muscle
-
doi: 10.1038/313316a0
-
Miller C, Moczydlowski E, Latorre R, Phillips M. 1985. Charybdotoxin, a protein inhibitor of single Ca2+-activated K+ channels from mammalian skeletal muscle. Nature 313:316-8. doi: 10.1038/313316a0.
-
(1985)
Nature
, vol.313
, pp. 316-318
-
-
Miller, C.1
Moczydlowski, E.2
Latorre, R.3
Phillips, M.4
-
40
-
-
0035499447
-
Energetic optimization of ion conduction rate by the K+ selectivity filter
-
doi: 10.1038/35102000
-
Morais-Cabral JH, Zhou Y, MacKinnon R. 2001. Energetic optimization of ion conduction rate by the K+ selectivity filter. Nature 414:37-42. doi: 10.1038/35102000.
-
(2001)
Nature
, vol.414
, pp. 37-42
-
-
Morais-Cabral, J.H.1
Zhou, Y.2
McKinnon, R.3
-
41
-
-
52949110988
-
Animal toxins acting on voltage-gated potassium channels
-
doi: 10.2174/138161208785777441
-
Mouhat S, Andreotti N, Jouirou B, Sabatier JM. 2008. Animal toxins acting on voltage-gated potassium channels. Curr Pharm Des 14:2503-18. doi: 10.2174/138161208785777441.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 2503-2518
-
-
Mouhat, S.1
Andreotti, N.2
Jouirou, B.3
Sabatier, J.M.4
-
42
-
-
0030002462
-
A symmetry-driven search for electrostatic interaction partners in charybdotoxin and a voltage-gated K+ channel
-
doi: 10.1021/bi960067s
-
Naini AA, Miller C. 1996. A symmetry-driven search for electrostatic interaction partners in charybdotoxin and a voltage-gated K+ channel. Biochemistry 35:6181-7. doi: 10.1021/bi960067s.
-
(1996)
Biochemistry
, vol.35
, pp. 6181-6187
-
-
Naini, A.A.1
Miller, C.2
-
43
-
-
0030044863
-
A strongly interacting pair of residues on the contact surface of charybdotoxin and a Shaker K+ channel
-
doi: 10.1016/S0896-6273(00)80029-X
-
Naranjo D, Miller C. 1996. A strongly interacting pair of residues on the contact surface of charybdotoxin and a Shaker K+ channel. Neuron 16:123-30. doi: 10.1016/S0896-6273(00)80029-X.
-
(1996)
Neuron
, vol.16
, pp. 123-130
-
-
Naranjo, D.1
Miller, C.2
-
44
-
-
34548386717
-
Crystal structure of a Kir3.1-prokaryotic Kir channel chimera
-
doi: 10.1038/sj.emboj.7601828
-
Nishida M, Cadene M, Chait BT, MacKinnon R. 2007. Crystal structure of a Kir3.1-prokaryotic Kir channel chimera. EMBO J 26:4005-15. doi: 10.1038/sj.emboj.7601828.
-
(2007)
EMBO J
, vol.26
, pp. 4005-4015
-
-
Nishida, M.1
Cadene, M.2
Chait, B.T.3
McKinnon, R.4
-
45
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski Z, Minor W. 1997. Processing of X-ray diffraction data collected in oscillation mode. Macromol Crystallogr Pt A 276:307-26.
-
(1997)
Macromol Crystallogr Pt A
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
46
-
-
0023225798
-
Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila
-
doi: 10.1126/science.2441470
-
Papazian DM, Schwarz TL, Tempel BL, Jan YN, Jan LY. 1987. Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila. Science 237:749-53. doi: 10.1126/science.2441470.
-
(1987)
Science
, vol.237
, pp. 749-753
-
-
Papazian, D.M.1
Schwarz, T.L.2
Tempel, B.L.3
Jan, Y.N.4
Jan, L.Y.5
-
47
-
-
0025966769
-
Design, synthesis, and functional expression of a gene for charybdotoxin, a peptide blocker of K+ channels
-
doi: 10.1073/pnas.88.6.2046
-
Park CS, Hausdorff SF, Miller C. 1991. Design, synthesis, and functional expression of a gene for charybdotoxin, a peptide blocker of K+ channels. Proc Natl Acad Sci USA 88:2046-50. doi: 10.1073/pnas.88.6.2046.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 2046-2050
-
-
Park, C.S.1
Hausdorff, S.F.2
Miller, C.3
-
48
-
-
0026803224
-
Interaction of charybdotoxin with permeant ions inside the pore of a K+ channel
-
doi: 10.1016/0896-6273(92)90169-E
-
Park CS, Miller C. 1992. Interaction of charybdotoxin with permeant ions inside the pore of a K+ channel. Neuron 9:307-13. doi: 10.1016/0896-6273(92)90169-E.
-
(1992)
Neuron
, vol.9
, pp. 307-313
-
-
Park, C.S.1
Miller, C.2
-
49
-
-
0030064382
-
Spatial localization of the K+ channel selectivity filter by mutant cycle-based structure analysis
-
doi: 10.1016/S0896-6273(00)80030-6
-
Ranganathan R, Lewis JH, MacKinnon R. 1996. Spatial localization of the K+ channel selectivity filter by mutant cycle-based structure analysis. Neuron 16:131-9. doi: 10.1016/S0896-6273(00)80030-6.
-
(1996)
Neuron
, vol.16
, pp. 131-139
-
-
Ranganathan, R.1
Lewis, J.H.2
McKinnon, R.3
-
50
-
-
0033966212
-
Structure-guided transformation of charybdotoxin yields an analog that selectively targets Ca(2+)-activated over voltage-gated K(+) channels
-
doi: 10.1074/jbc.275.2.1201
-
Rauer H, Lanigan MD, Pennington MW, Aiyar J, Ghanshani S, Cahalan MD, et al. 2000. Structure-guided transformation of charybdotoxin yields an analog that selectively targets Ca(2+)-activated over voltage-gated K(+) channels. J Biol Chem 275:1201-8. doi: 10.1074/jbc.275.2.1201.
-
(2000)
J Biol Chem
, vol.275
, pp. 1201-1208
-
-
Rauer, H.1
Lanigan, M.D.2
Pennington, M.W.3
Aiyar, J.4
Ghanshani, S.5
Cahalan, M.D.6
-
51
-
-
77954706736
-
Mining on scorpion venom biodiversity
-
doi: 10.1016/j.toxicon.2009.11.010
-
Rodriguez de la Vega RC, Schwartz EF, Possani LD. 2010. Mining on scorpion venom biodiversity. Toxicon 56:1155-61. doi: 10.1016/j.toxicon.2009.11.010.
-
(2010)
Toxicon
, vol.56
, pp. 1155-1161
-
-
de la Rodriguez Vega, R.C.1
Schwartz, E.F.2
Possani, L.D.3
-
52
-
-
0026729447
-
Mapping hydrophobic residues of the interaction surface of charybdotoxin
-
doi: 10.1016/S0006-3495(92)81761-7
-
Stampe P, Kolmakova-Partensky L, Miller C. 1992. Mapping hydrophobic residues of the interaction surface of charybdotoxin. Biophys J 62:8-9. doi: 10.1016/S0006-3495(92)81761-7.
-
(1992)
Biophys J
, vol.62
, pp. 8-9
-
-
Stampe, P.1
Kolmakova-Partensky, L.2
Miller, C.3
-
53
-
-
0028117321
-
Intimations of K+ channel structure from a complete functional map of the molecular surface of charybdotoxin
-
doi: 10.1021/bi00168a008
-
Stampe P, Kolmakova-Partensky L, Miller C. 1994. Intimations of K+ channel structure from a complete functional map of the molecular surface of charybdotoxin. Biochemistry 33:443-50. doi: 10.1021/bi00168a008.
-
(1994)
Biochemistry
, vol.33
, pp. 443-450
-
-
Stampe, P.1
Kolmakova-Partensky, L.2
Miller, C.3
-
54
-
-
0028031088
-
Electrostatic distance geometry in a K+ channel vestibule
-
doi: 10.1073/pnas.91.20.9509
-
Stocker M, Miller C. 1994. Electrostatic distance geometry in a K+ channel vestibule. Proc Natl Acad Sci USA 91:9509-13. doi: 10.1073/pnas.91.20.9509.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9509-9513
-
-
Stocker, M.1
Miller, C.2
-
55
-
-
0028811258
-
An inhibitor of the Kv2.1 potassium channel isolated from the venom of a Chilean tarantula
-
doi: 10.1016/0896-6273(95)90184-1
-
Swartz KJ, MacKinnon R. 1995. An inhibitor of the Kv2.1 potassium channel isolated from the venom of a Chilean tarantula. Neuron 15:941-9. doi: 10.1016/0896-6273(95)90184-1.
-
(1995)
Neuron
, vol.15
, pp. 941-949
-
-
Swartz, K.J.1
McKinnon, R.2
-
56
-
-
0030935699
-
Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+ channels
-
doi: 10.1016/S0896-6273(00)80307-4
-
Swartz KJ, MacKinnon R. 1997. Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+ channels. Neuron 18:675-82. doi: 10.1016/S0896-6273(00)80307-4.
-
(1997)
Neuron
, vol.18
, pp. 675-682
-
-
Swartz, K.J.1
McKinnon, R.2
-
57
-
-
0242458492
-
Structural basis of the KcsA K(+) channel and AgTx2 pore-blocking toxin interaction by using the transferred cross-saturation method
-
doi: 10.1016/j.str.2003.10.003
-
Takeuchi K, Yokogawa M, Matsuda T, Sugai M, Kawano S, Kohno T, et al. 2003. Structural basis of the KcsA K(+) channel and AgTx2 pore-blocking toxin interaction by using the transferred cross-saturation method. Structure 11:1381-92. doi: 10.1016/j.str.2003.10.003.
-
(2003)
Structure
, vol.11
, pp. 1381-1392
-
-
Takeuchi, K.1
Yokogawa, M.2
Matsuda, T.3
Sugai, M.4
Kawano, S.5
Kohno, T.6
-
58
-
-
49349111148
-
Functional analysis of Kv1.2 and paddle chimera Kv channels in planar lipid bilayers
-
doi: 10.1016/j.jmb.2008.06.085
-
Tao X, MacKinnon R. 2008. Functional analysis of Kv1.2 and paddle chimera Kv channels in planar lipid bilayers. J Mol Biol 382:24-33. doi: 10.1016/j.jmb.2008.06.085.
-
(2008)
J Mol Biol
, vol.382
, pp. 24-33
-
-
Tao, X.1
McKinnon, R.2
-
59
-
-
0027439390
-
Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin
-
doi: 10.1006/jmbi.1993.1012
-
van Duyne GD, Standaert RF, Karplus PA, Schreiber SL, Clardy J. 1993. Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin. J Mol Biol 229:105-24. doi: 10.1006/jmbi.1993.1012.
-
(1993)
J Mol Biol
, vol.229
, pp. 105-124
-
-
van Duyne, G.D.1
Standaert, R.F.2
Karplus, P.A.3
Schreiber, S.L.4
Clardy, J.5
-
60
-
-
61949466107
-
Integrated oxidative folding of cysteine/selenocysteine containing peptides: Improving chemical synthesis of conotoxins
-
doi: 10.1002/anie.200806085
-
Walewska A, Zhang MM, Skalicky JJ, Yoshikami D, Olivera BM, Bulaj G. 2009. Integrated oxidative folding of cysteine/selenocysteine containing peptides: improving chemical synthesis of conotoxins. Angew Chem Int Ed Engl 48:2221-4. doi: 10.1002/anie.200806085.
-
(2009)
Angew Chem Int Ed Engl
, vol.48
, pp. 2221-2224
-
-
Walewska, A.1
Zhang, M.M.2
Skalicky, J.J.3
Yoshikami, D.4
Olivera, B.M.5
Bulaj, G.6
-
61
-
-
28544434796
-
Nuclear magnetic resonance structural studies of a potassium channel-charybdotoxin complex
-
doi: 10.1021/bi051656d
-
Yu L, Sun C, Song D, Shen J, XU N, Gunasekera A, et al. 2005. Nuclear magnetic resonance structural studies of a potassium channel-charybdotoxin complex. Biochemistry 44:15834-41. doi: 10.1021/bi051656d.
-
(2005)
Biochemistry
, vol.44
, pp. 15834-15841
-
-
Yu, L.1
Sun, C.2
Song, D.3
Shen, J.4
Xu, N.5
Gunasekera, A.6
-
62
-
-
0142185496
-
The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
-
doi: 10.1016/j.jmb.2003.09.022
-
Zhou Y, MacKinnon R. 2003. The occupancy of ions in the K+ selectivity filter: charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates. J Mol Biol 333:965-75. doi: 10.1016/j.jmb.2003.09.022.
-
(2003)
J Mol Biol
, vol.333
, pp. 965-975
-
-
Zhou, Y.1
McKinnon, R.2
-
63
-
-
0035499892
-
Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution
-
doi: 10.1038/35102009
-
Zhou Y, Morais-Cabral JH, Kaufman A, MacKinnon R. 2001. Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature 414:43-8. doi: 10.1038/35102009.
-
(2001)
Nature
, vol.414
, pp. 43-48
-
-
Zhou, Y.1
Morais-Cabral, J.H.2
Kaufman, A.3
McKinnon, R.4
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