The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease

Journal of Experimental Medicine

Volumn 213, Issue 3, 2016, Pages 337-354

  Shirai, Tsuyoshi ^a   Nazarewicz, Rafal R ^a,b   Wallis, Barbara B ^a   Yanes, Rolando E ^a   Watanabe, Ryu ^a   Hilhorst, Marc ^a   Tian, Lu ^a   Harrison, David G ^b   Giacomini, John C ^a   Assimes, Themistocles L ^a   Goronzy, Jörg J ^a   Weyand, Cornelia M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCOLYTIC ENZYME; INTERLEUKIN 1BETA; INTERLEUKIN 6; PYRUVATE KINASE; PYRUVATE KINASE M2; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; SUPEROXIDE; UNCLASSIFIED DRUG;

ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CYTOKINE PRODUCTION; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; GLYCOLYSIS; HUMAN; HUMAN CELL; MACROPHAGE; MACROPHAGE FUNCTION; METABOLIC DISORDER; MONOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; AGED; BIOSYNTHESIS; CELL RESPIRATION; CORONARY ARTERY DISEASE; ENZYMOLOGY; FEMALE; INFLAMMATION; MALE; METABOLISM; MITOCHONDRION; PATHOLOGY; PHENOTYPE; PHOSPHORYLATION; PROTEIN MULTIMERIZATION;

AGED; CELL RESPIRATION; CORONARY ARTERY DISEASE; FEMALE; GLUCOSE; GLYCOLYSIS; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; MACROPHAGES; MALE; MITOCHONDRIA; MONOCYTES; PHENOTYPE; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; PYRUVATE KINASE; REACTIVE OXYGEN SPECIES; STAT3 TRANSCRIPTION FACTOR;

EID: 84961226298     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20150900     Document Type: Article

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