Distribution of macrophage polarization markers in human atherosclerosis

Atherosclerosis

Volumn 225, Issue 2, 2012, Pages 461-468

  Stöger, J Lauran ^a,b   Gijbels, Marion J J ^a,b   van der Velden, Saskia ^b   Manca, Marco ^a   van der Loos, Chris M ^b   Biessen, Erik A L ^a   Daemen, Mat J A P ^b   Lutgens, Esther ^b   de Winther, Menno P J ^b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Coronary artery disease; Foam cell; Human pathology; Innate immunity; Macrophages

Indexed keywords

CD163 ANTIGEN; CD68 ANTIGEN; CELL MARKER; CELL PROTEIN; MESSENGER RNA;

ADULT; AGED; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL POLARITY; CELL STRUCTURE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; FEMALE; FOAM CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MARKER GENE; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS;

ADVENTITIA; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CAROTID ARTERIES; CAROTID ARTERY DISEASES; DISEASE PROGRESSION; FEMALE; FIBROSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; MACROPHAGES; MALE; PLAQUE, ATHEROSCLEROTIC; RNA, MESSENGER; RUPTURE, SPONTANEOUS; SEVERITY OF ILLNESS INDEX; TRANSCRIPTOME;

EID: 84869491455     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.09.013     Document Type: Article

References (39)

1. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999 Jan. 14, 340(2):115-126.
2. Lopez A.D., Mathers C.D., Ezzati M., Jamison D.T., Murray C.J.L. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006 May 27, 367(9524):1747-1757.
3. Moreno P.R., Falk E., Palacios I.F., Newell J.B., Fuster V., Fallon J.T. Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture. Circulation 1994 Aug., 90(2):775-778.
4. van der Wal A.C., Becker A.E., van der Loos C.M., Das P.K. Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation 1994 Jan., 89(1):36-44.
5. Martinez F.O., Sica A., Mantovani A., Locati M. Macrophage activation and polarization. Front Biosci 2008, 13:453-461.
6. Martinez F.O., Gordon S., Locati M., Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol 2006 Nov. 15, 177(10):7303-7311.
7. Lumeng C.N., Bodzin J.L., Saltiel A.R. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007 Jan. 2, 117(1):175-184.
8. Mantovani A., Sozzani S., Locati M., Allavena P., Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002 Nov., 23(11):549-555.
9. Khallou-Laschet J., Varthaman A., Fornasa G., et al. Macrophage plasticity in experimental atherosclerosis. PLoS ONE 2010 Jan. 25, 5(1):e8852. Fritz JH, editor.
10. Bouhlel M.A., Derudas B., Rigamonti E., et al. PPARγ activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metab 2007 Aug., 6(2):137-143.
11. Waldo S.W., Li Y., Buono C., et al. Heterogeneity of human macrophages in culture and in atherosclerotic plaques. Am J Pathol 2008 Apr., 172(4):1112-1126.
12. Finn A.V., Nakano M., Polavarapu R., et al. Hemoglobin directs macrophage differentiation and prevents foam cell formation in human atherosclerotic plaques. J Am Coll Cardiol 2012 Jan. 10, 59(2):166-177.
13. Kadl A., Meher A.K., Sharma P.R., et al. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circ Res 2010 Sep. 17, 107(6):737-746.
14. Gleissner C.A., Shaked I., Little K.M., Ley K. CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages. J Immunol 2010 Apr. 21, 184(9):4810-4818.
15. Wolfs I.M.J., Donners M.M.P.C., de Winther M.P.J. Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation. Thromb Haemost 2011, 106(5):763-771.
16. Mantovani A., Garlanda C., Locati M. Macrophage diversity and polarization in atherosclerosis: a question of balance. Arterioscler Thromb Vasc Biol 2009 Sep. 16, 29(10):1419-1423.
17. Goossens P., Gijbels M.J.J., Zernecke A., et al. Myeloid type i interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions. Cell Metab 2010 Aug. 4, 12(2):142-153. Elsevier Ltd.
18. Virmani R., Kolodgie F.D., Burke A.P., Farb A., Schwartz S.M. Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2000 May, 20(5):1262-1275.
19. van der Loos C.M. Multiple immunoenzyme staining: methods and visualizations for the observation with spectral imaging. J Histochem Cytochem 2008 Apr., 56(4):313-328.
20. Papaspyridonos M., Smith A., Burnand K.G., et al. Novel candidate genes in unstable areas of human atherosclerotic plaques. Arterioscler Thromb Vasc Biol 2006 Aug., 26(8):1837-1844.
21. Boyle J.J., Harrington H.A., Piper E., et al. Coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype. Am J Pathol 2009 Mar., 174(3):1097-1108.
22. Pasterkamp G., Schoneveld A.H., van der Wal A.C., et al. Inflammation of the atherosclerotic cap and shoulder of the plaque is a common and locally observed feature in unruptured plaques of femoral and coronary arteries. Arterioscler Thromb Vasc Biol 1999 Jan. 1, 19(1):54-58.
23. Galkina E., Kadl A., Sanders J., Varughese D., Sarembock I.J., Ley K. Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent. J Exp Med 2006 May 15, 203(5):1273-1282.
24. Chinetti-Gbaguidi G., Baron M., Bouhlel M.A., et al. Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPAR and LXR pathways. Circ Res 2011 Apr. 14, 108(8):985-995.
25. Shalhoub J., Falck-Hansen M.A., Davies A.H., Monaco C. Innate immunity and monocyte-macrophage activation in atherosclerosis. J Inflamm 2011, 8:9.
26. Poston R.N., Hussain I.F. The immunohistochemical heterogeneity of atheroma macrophages: comparison with lymphoid tissues suggests that recently blood-derived macrophages can be distinguished from longer-resident cells. J Histochem Cytochem 1993 Oct., 41(10):1503-1512.
27. Sindrilaru A., Peters T., Wieschalka S., et al. An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. J Clin Invest 2011 Mar. 1, 121(3):985-997.
28. Maiellaro K., Taylor W.R. The role of the adventitia in vascular inflammation. Cardiovasc Res 2007 Sep. 1, 75(4):640-648.
29. Moulton K.S., Vakili K., Zurakowski D., et al. Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis. Proc Natl Acad Sci USA 2003 Apr. 15, 100(8):4736-4741.
30. Odegaard J.I., Ricardo-Gonzalez R.R., Goforth M.H., et al. Macrophage-specific PPARγ controls alternative activation and improves insulin resistance. Nature 2007 May 21, 447(7148):1116-1120.
31. Morris D.L., Singer K., Lumeng C.N. Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states. Curr Opin Clin Nutr Metab Care 2011 Jul., 14(4):341-346.
32. Anyfanti P., Doumas M., Gavriilaki E., Triantafyllou A., Nikolaidou B. More fuel in the obesity paradox debate. Int J Obes 2012, [Epub ahead of print].
33. Clark A.L., Chyu J., Horwich T.B. The obesity paradox in men versus women with systolic heart failure. Am J Cardiol 2012 Jul. 1, 110(1):77-82.
34. Younge JO, Damen NL, van Domburg RT, Pedersen SS. Obesity, health status, and 7-year mortality in percutaneous coronary intervention: in search of an explanation for the obesity paradox. Int J Cardiol 2012, http://dx.doi.org/10.1016/j.ijcard.2012.03.105.
35. Feig J.E., Parathath S., Rong J.X., et al. Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques. Circulation 2011 Mar. 7, 123(9):989-998.
36. Falk E., Shah P.K., Fuster V. Coronary plaque disruption. Circulation 1995 Aug. 1, 92(3):657-671.
37. Duffield J.S. The inflammatory macrophage: a story of Jekyll and Hyde. Clin Sci 2003 Jan., 104(1):27-38.
38. Shalhoub J., Cross A., Allin D., Essex D., Davies A., Monaco C. BAS/BSCR36 cytokine profiling in culture reveals a predominance of M1 macrophage polarisation in symptomatic carotid plaques. Heart 2010 Aug. 26, 96(17):e23-3. [Internet]. Available from:. http://heart.bmj.com/cgi/doi/10.1136/hrt.2010.205781.49.
39. Hirata Y., Tabata M., Kurobe H., et al. Coronary atherosclerosis is associated with macrophage polarization in epicardial adipose tissue. J Am Coll Cardiol 2011 Jul. 12, 58(3):248-255.