The delta 6 desaturase knock out mouse reveals that immunomodulatory effects of essential n-6 and n-3 polyunsaturated fatty acids are both independent of and dependent upon conversion

Journal of Nutritional Biochemistry

Volumn 32, Issue , 2016, Pages 29-38

  Monk, Jennifer M ^a,b   Liddle, Danyelle M ^a   Cohen, Daniel J A ^a   Tsang, Denis H ^a   Hillyer, Lyn M ^a   Abdelmagid, Salma A ^a   Nakamura, Manabu T ^c   Power, Krista A ^a,b   Ma, David W L ^a   Robinson, Lindsay E ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b AGRICULTURE AND AGRI FOOD CANADA   (Canada)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Cytokines; Fatty acid desaturase 2; Fatty acid metabolism; Inflammation; Polyunsaturated fatty acid

Indexed keywords

ARACHIDONIC ACID; CORN OIL; GAMMA INTERFERON; INTERLEUKIN 10; LINOLEIC ACID; LINOLEOYL COENZYME A DESATURASE; LINSEED OIL; LIPOPOLYSACCHARIDE; MENHADEN OIL; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; ACYL COENZYME A DESATURASE; CYTOKINE; DELTA-6 DESATURASE, MOUSE; LIPOPOLYSACCHARIDE, E COLI O55-B5;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL POPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; FATTY ACID METABOLISM; FEMALE; IMMUNOCOMPETENT CELL; LIPID COMPOSITION; MALE; MONONUCLEAR CELL; MOUSE; NONHUMAN; SPLENIC TISSUE; ANIMAL; CELL CULTURE; COMPARATIVE STUDY; CROSS BREEDING; CYTOLOGY; DIETARY SUPPLEMENT; DRUG EFFECTS; GENETICS; IMMUNOLOGY; IMMUNOMODULATION; KNOCKOUT MOUSE; METABOLISM; SECRETION (PROCESS); SPLEEN;

ANIMALS; CELLS, CULTURED; CROSSES, GENETIC; CYTOKINES; DIETARY SUPPLEMENTS; FATTY ACID DESATURASES; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FEMALE; IMMUNOMODULATION; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, KNOCKOUT; SPLEEN;

EID: 84961158933     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2016.01.004     Document Type: Article

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