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Volumn 85, Issue 2, 2007, Pages 385-391

Dietary α-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects

Author keywords

Eicosapentaenoic acid; Hypercholesterolemic subjects; Interleukin 1 ; Interleukin 6; Peripheral blood mononuclear cells; Tumor necrosis factor ; linolenic acid

Indexed keywords

CYTOKINE; ICOSAPENTAENOIC ACID; INTERLEUKIN 1BETA; INTERLEUKIN 6; LINOLEIC ACID; TUMOR NECROSIS FACTOR ALPHA;

EID: 33846867711     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/85.2.385     Document Type: Article
Times cited : (266)

References (42)
  • 1
    • 0032955055 scopus 로고    scopus 로고
    • Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: Final report of the Lyon Diet Heart Study
    • de Lorgeril M, Salen P, Martin JL, Monjaud I, Delaye J, Mamelle N. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation 1999;99:779-85.
    • (1999) Circulation , vol.99 , pp. 779-785
    • de Lorgeril, M.1    Salen, P.2    Martin, J.L.3    Monjaud, I.4    Delaye, J.5    Mamelle, N.6
  • 2
    • 0032949296 scopus 로고    scopus 로고
    • Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among women
    • Hu FB, Stampfer MJ, Manson JE, et al. Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among women. Am J Clin Nutr 1999;69:890-7.
    • (1999) Am J Clin Nutr , vol.69 , pp. 890-897
    • Hu, F.B.1    Stampfer, M.J.2    Manson, J.E.3
  • 3
    • 0034748162 scopus 로고    scopus 로고
    • Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart Study
    • Djousse L, Pankow JS, Eckfeldt JH, et al. Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart Study. Am J Clin Nutr 2001;74:612-9.
    • (2001) Am J Clin Nutr , vol.74 , pp. 612-619
    • Djousse, L.1    Pankow, J.S.2    Eckfeldt, J.H.3
  • 4
    • 7944228499 scopus 로고    scopus 로고
    • Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women
    • Zhao G, Etherton TD, Martin KR, West SG, Gillies PJ, Kris-Etherton PM. Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women. J Nutr 2004;134:2991-7.
    • (2004) J Nutr , vol.134 , pp. 2991-2997
    • Zhao, G.1    Etherton, T.D.2    Martin, K.R.3    West, S.G.4    Gillies, P.J.5    Kris-Etherton, P.M.6
  • 5
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005;352:1685-95.
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 6
    • 33644872836 scopus 로고    scopus 로고
    • Inflammation and cardiovascular disease mechanisms
    • Libby P. Inflammation and cardiovascular disease mechanisms. Am J Clin Nutr 2006;83(suppl):456S-60S.
    • (2006) Am J Clin Nutr , vol.83 , Issue.SUPPL.
    • Libby, P.1
  • 7
    • 0037421497 scopus 로고    scopus 로고
    • Vascular biology of atherosclerosis: Overview and state of the art
    • Libby P. Vascular biology of atherosclerosis: overview and state of the art. Am J Cardiol 2003;91:3A-6A.
    • (2003) Am J Cardiol , vol.91
    • Libby, P.1
  • 8
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis. the road ahead
    • Glass CK, Witztum JL. Atherosclerosis. the road ahead. Cell 2001;104:503-16.
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 9
    • 0026642471 scopus 로고
    • C-reactive protein levels as a direct indicator of interleukin-6 levels in humans in vivo
    • Bataille R, Klein B. C-reactive protein levels as a direct indicator of interleukin-6 levels in humans in vivo. Arthritis Rheum 1992;35:982-4.
    • (1992) Arthritis Rheum , vol.35 , pp. 982-984
    • Bataille, R.1    Klein, B.2
  • 10
    • 0033956866 scopus 로고    scopus 로고
    • Fatty acid modulation of endothelial activation
    • De Caterina R, Liao JK, Libby P. Fatty acid modulation of endothelial activation. Am J Clin Nutr 2000;71(suppl):213S-23S.
    • (2000) Am J Clin Nutr , vol.71 , Issue.SUPPL.
    • De Caterina, R.1    Liao, J.K.2    Libby, P.3
  • 11
    • 0024489402 scopus 로고
    • The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells
    • Endres S, Ghorbani R, Kelley VE, et al. The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N Engl J Med 1989;320:265-71.
    • (1989) N Engl J Med , vol.320 , pp. 265-271
    • Endres, S.1    Ghorbani, R.2    Kelley, V.E.3
  • 12
    • 0025782730 scopus 로고
    • Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: Comparison between young and older women
    • Meydani SN, Endres S, Woods MM, et al. Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: comparison between young and older women. J Nutr 1991;121:547-55.
    • (1991) J Nutr , vol.121 , pp. 547-555
    • Meydani, S.N.1    Endres, S.2    Woods, M.M.3
  • 13
    • 0033957165 scopus 로고    scopus 로고
    • Dietary polyunsaturated fatty acids and inflammatory mediator production
    • James MJ, Gibson RA, Cleland LG. Dietary polyunsaturated fatty acids and inflammatory mediator production. Am J Clin Nutr 2000;71(suppl):343S-8S.
    • (2000) Am J Clin Nutr , vol.71 , Issue.SUPPL.
    • James, M.J.1    Gibson, R.A.2    Cleland, L.G.3
  • 14
    • 0030038986 scopus 로고    scopus 로고
    • The effect on human tumor necrosis factor α and interleukin 1β production of diets enriched in n-3 fatty acids from vegetable oil or fish oil
    • Caughey GE, Mantzioris E, Gibson RA, Cleland LG, James MJ. The effect on human tumor necrosis factor α and interleukin 1β production of diets enriched in n-3 fatty acids from vegetable oil or fish oil. Am J Clin Nutr 1996;63:116-22.
    • (1996) Am J Clin Nutr , vol.63 , pp. 116-122
    • Caughey, G.E.1    Mantzioris, E.2    Gibson, R.A.3    Cleland, L.G.4    James, M.J.5
  • 15
    • 0032895369 scopus 로고    scopus 로고
    • Docosahexaenoic acid ingestion inhibits natural killer cell activity and production of inflammatory mediators in young healthy men
    • Kelley DS, Taylor PC, Nelson GJ, et al. Docosahexaenoic acid ingestion inhibits natural killer cell activity and production of inflammatory mediators in young healthy men. Lipids 1999;34:317-24.
    • (1999) Lipids , vol.34 , pp. 317-324
    • Kelley, D.S.1    Taylor, P.C.2    Nelson, G.J.3
  • 16
    • 0034946482 scopus 로고    scopus 로고
    • Dietary supplementation with gamma-linolenic acid or fish oil decreases T lymphocyte proliferation in healthy older humans
    • Thies F, Nebe-von-Caron G, Powell JR, Yaqoob P, Newsholme EA, Calder PC. Dietary supplementation with gamma-linolenic acid or fish oil decreases T lymphocyte proliferation in healthy older humans. J Nutr 2001;131:1918-27.
    • (2001) J Nutr , vol.131 , pp. 1918-1927
    • Thies, F.1    Nebe-von-Caron, G.2    Powell, J.R.3    Yaqoob, P.4    Newsholme, E.A.5    Calder, P.C.6
  • 17
    • 0035117798 scopus 로고    scopus 로고
    • Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n-3 or n-6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y
    • Thies F, Nebe-von-Caron G, Powell JR, Yaqoob P, Newsholme EA, Calder PC. Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n-3 or n-6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y. Am J Clin Nutr 2001;73:539-48.
    • (2001) Am J Clin Nutr , vol.73 , pp. 539-548
    • Thies, F.1    Nebe-von-Caron, G.2    Powell, J.R.3    Yaqoob, P.4    Newsholme, E.A.5    Calder, P.C.6
  • 18
    • 0038474032 scopus 로고    scopus 로고
    • Lack of effect of foods enriched with plant- or marine-derived n-3 fatty acids on human immune function
    • Kew S, Banerjee T, Minihane AM, et al. Lack of effect of foods enriched with plant- or marine-derived n-3 fatty acids on human immune function. Am J Clin Nutr 2003;77:1287-95.
    • (2003) Am J Clin Nutr , vol.77 , pp. 1287-1295
    • Kew, S.1    Banerjee, T.2    Minihane, A.M.3
  • 19
    • 25144444150 scopus 로고    scopus 로고
    • Anti-inflammatory effects of polyunsaturated fatty acids in THP-1 cells
    • Zhao G, Etherton TD, Martin KR, et al. Anti-inflammatory effects of polyunsaturated fatty acids in THP-1 cells. Biochem Biophys Res Comm 2005;336:909-17.
    • (2005) Biochem Biophys Res Comm , vol.336 , pp. 909-917
    • Zhao, G.1    Etherton, T.D.2    Martin, K.R.3
  • 20
    • 0036134744 scopus 로고    scopus 로고
    • Unsaturated fatty acids selectively induce an inflammatory environment in human endothelial cells
    • Toborek M, Lee YW, Garrido R, Kaiser S, Hennig B. Unsaturated fatty acids selectively induce an inflammatory environment in human endothelial cells. Am J Clin Nutr 2002;75:119-25.
    • (2002) Am J Clin Nutr , vol.75 , pp. 119-125
    • Toborek, M.1    Lee, Y.W.2    Garrido, R.3    Kaiser, S.4    Hennig, B.5
  • 21
    • 0034937107 scopus 로고    scopus 로고
    • Modulation of human immune and inflammatory responses by dietary fatty acids
    • Kelley DS. Modulation of human immune and inflammatory responses by dietary fatty acids. Nutrition 2001;17:669-73.
    • (2001) Nutrition , vol.17 , pp. 669-673
    • Kelley, D.S.1
  • 22
    • 0346887196 scopus 로고    scopus 로고
    • Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells
    • Viswanathan S, Hammock BD, Newman JW, Meerarani P, Toborek M, Hennig B. Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells. J Am Coll Nutr 2003;22:502-10.
    • (2003) J Am Coll Nutr , vol.22 , pp. 502-510
    • Viswanathan, S.1    Hammock, B.D.2    Newman, J.W.3    Meerarani, P.4    Toborek, M.5    Hennig, B.6
  • 23
    • 33749659221 scopus 로고    scopus 로고
    • Linoleic acid induces proinflammatory events in vascular endothelial cells via activation of PI3K/Akt and ERK1/2 signaling
    • Hennig B, Lei W, Arzuaga X, Ghosh DD, Viswanathan S, Toborek M. Linoleic acid induces proinflammatory events in vascular endothelial cells via activation of PI3K/Akt and ERK1/2 signaling. J Nutr Biochem 2006;17:766-72.
    • (2006) J Nutr Biochem , vol.17 , pp. 766-772
    • Hennig, B.1    Lei, W.2    Arzuaga, X.3    Ghosh, D.D.4    Viswanathan, S.5    Toborek, M.6
  • 24
    • 3142729178 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
    • Grundy SM, Cleeman JI, Merz CN, et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation 2004;110:227-39.
    • (2004) Circulation , vol.110 , pp. 227-239
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.3
  • 25
    • 0035226546 scopus 로고    scopus 로고
    • Interleukin-1 and related proteins in cardiovascular disease in adults and children
    • Loppnow H, Westphal E, Buchhorn R, Wessel A, Werdan K. Interleukin-1 and related proteins in cardiovascular disease in adults and children. Shock 2001;16:3-9.
    • (2001) Shock , vol.16 , pp. 3-9
    • Loppnow, H.1    Westphal, E.2    Buchhorn, R.3    Wessel, A.4    Werdan, K.5
  • 26
    • 0033037150 scopus 로고    scopus 로고
    • Interleukin-6 as a central mediator of cardiovascular risk associated with chronic inflammation, smoking, diabetes, and visceral obesity: Down-regulation with essential fatty acids, ethanol and pentoxifylline
    • McCarty MF. Interleukin-6 as a central mediator of cardiovascular risk associated with chronic inflammation, smoking, diabetes, and visceral obesity: down-regulation with essential fatty acids, ethanol and pentoxifylline. Med Hypotheses 1999;52:465-77.
    • (1999) Med Hypotheses , vol.52 , pp. 465-477
    • McCarty, M.F.1
  • 27
    • 0036522142 scopus 로고    scopus 로고
    • Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men
    • Skoog T, Dichtl W, Boquist S, et al. Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men. Eur Heart J 2002;23:376-83.
    • (2002) Eur Heart J , vol.23 , pp. 376-383
    • Skoog, T.1    Dichtl, W.2    Boquist, S.3
  • 28
    • 0038447923 scopus 로고    scopus 로고
    • Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory markers among US men and women
    • Pischon T, Hankinson SE, Hotamisligil GS, Rifai N, Willett WC, Rimm EB. Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory markers among US men and women. Circulation 2003;108:155-60.
    • (2003) Circulation , vol.108 , pp. 155-160
    • Pischon, T.1    Hankinson, S.E.2    Hotamisligil, G.S.3    Rifai, N.4    Willett, W.C.5    Rimm, E.B.6
  • 29
    • 0030615201 scopus 로고    scopus 로고
    • Barnes PJ, Karin M. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997;336:1066-71.
    • Barnes PJ, Karin M. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997;336:1066-71.
  • 30
    • 0034255365 scopus 로고    scopus 로고
    • The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation
    • Hajra L, Evans AI, Chen M, Hyduk SJ, Collins T, Cybulsky MI. The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation. Proc Natl Acad Sci U S A 2000;97:9052-7.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 9052-9057
    • Hajra, L.1    Evans, A.I.2    Chen, M.3    Hyduk, S.J.4    Collins, T.5    Cybulsky, M.I.6
  • 32
    • 0032757209 scopus 로고    scopus 로고
    • Atorvastatin reduces NF-kappaB activation and chemokine expression in vascular smooth muscle cells and mononuclear cells
    • Ortego M, Bustos C, Hernandez-Presa MA, et al. Atorvastatin reduces NF-kappaB activation and chemokine expression in vascular smooth muscle cells and mononuclear cells. Atherosclerosis 1999;147:253-61.
    • (1999) Atherosclerosis , vol.147 , pp. 253-261
    • Ortego, M.1    Bustos, C.2    Hernandez-Presa, M.A.3
  • 33
    • 0033045291 scopus 로고    scopus 로고
    • Oleic acid inhibits endothelial activation: A direct vascular antiatherogenic mechanism of a nutritional component in the Mediterranean diet
    • Carluccio MA, Massaro M, Bonfrate C, et al. Oleic acid inhibits endothelial activation: a direct vascular antiatherogenic mechanism of a nutritional component in the Mediterranean diet. Arterioscler Thromb Vasc Biol 1999;19:220-8.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 220-228
    • Carluccio, M.A.1    Massaro, M.2    Bonfrate, C.3
  • 34
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998;391:79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 35
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998;391:82-6.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 36
    • 0036345845 scopus 로고    scopus 로고
    • Circulating ICAM-1 (intercellular cell-adhesion molecule 1) is associated with early stages of atherosclerosis development and with inflammatory cytokines in healthy 58-year-old men: The Atherosclerosis and Insulin Resistance (AIR) study
    • Hulthe J, Wikstrand J, Mattsson-Hulten L, Fagerberg B. Circulating ICAM-1 (intercellular cell-adhesion molecule 1) is associated with early stages of atherosclerosis development and with inflammatory cytokines in healthy 58-year-old men: the Atherosclerosis and Insulin Resistance (AIR) study. Clin Sci 2002;103:123-9.
    • (2002) Clin Sci , vol.103 , pp. 123-129
    • Hulthe, J.1    Wikstrand, J.2    Mattsson-Hulten, L.3    Fagerberg, B.4
  • 37
    • 0032559831 scopus 로고    scopus 로고
    • Expression and regulation of adhesion molecules in cardiac cells by cytokines: Response to acute hypoxia
    • Kacimi R, Karliner JS, Koudssi F, Long CS. Expression and regulation of adhesion molecules in cardiac cells by cytokines: response to acute hypoxia. Circ Res 1998;82:576-86.
    • (1998) Circ Res , vol.82 , pp. 576-586
    • Kacimi, R.1    Karliner, J.S.2    Koudssi, F.3    Long, C.S.4
  • 38
    • 0028172777 scopus 로고
    • The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells
    • De Caterina R, Cybulsky MI, Clinton SK, Gimbrone MA Jr, Libby P. The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells. Arterioscler Thromb 1994;14:1829-36.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1829-1836
    • De Caterina, R.1    Cybulsky, M.I.2    Clinton, S.K.3    Gimbrone Jr, M.A.4    Libby, P.5
  • 40
    • 0036059811 scopus 로고    scopus 로고
    • C-reactive protein levels are influenced by common IL-1 gene variations
    • Berger P, McConnell JP, Nunn M, et al. C-reactive protein levels are influenced by common IL-1 gene variations. Cytokine 2002;17:171-4.
    • (2002) Cytokine , vol.17 , pp. 171-174
    • Berger, P.1    McConnell, J.P.2    Nunn, M.3
  • 42
    • 20744438060 scopus 로고    scopus 로고
    • Balance of unsaturated fatty acids is important to a cholesterol-lowering diet: Comparison of mid-oleic sunflower oil and olive oil on cardiovascular disease risk factors
    • Binkoski AE, Kris-Etherton PM, Wilson TA, Mountain ML, Nicolosi RJ. Balance of unsaturated fatty acids is important to a cholesterol-lowering diet: comparison of mid-oleic sunflower oil and olive oil on cardiovascular disease risk factors. J Am Diet Assoc 2005;105:1080-6.
    • (2005) J Am Diet Assoc , vol.105 , pp. 1080-1086
    • Binkoski, A.E.1    Kris-Etherton, P.M.2    Wilson, T.A.3    Mountain, M.L.4    Nicolosi, R.J.5


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