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Volumn 171, Issue 12, 2003, Pages 6856-6865

Reduced Inflammation and Tissue Damage in Transgenic Rabbits Overexpressing 15-Lipoxygenase and Endogenous Anti-inflammatory Lipid Mediators

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 5,8,11,13 ICOSATETRAENOIC ACID; 15-HYDROXY-5,8,11,13-EICOSATETRAENOIC ACID; 16 (4 FLUOROPHENOXY)LIPOXIN A4; 16-(4-FLUOROPHENOXY)LIPOXIN A4; 5,15 DIHYDROXY 6,8,11,13 ICOSATETRAENOIC ACID; 5,15-DIHYDROXY-6,8,11,13-EICOSATETRAENOIC ACID; ANTIINFLAMMATORY AGENT; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONATE 5 LIPOXYGENASE; CHEMOTACTIC PEPTIDE; ESTER; HYDROXYICOSATETRAENOIC ACID; ICOSANOID; INTERLEUKIN 8; LEUKOTRIENE; LEUKOTRIENE A4; LEUKOTRIENE B4; LIPID; LIPOXIN; LIPOXIN A; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHOLIPID; PROSTAGLANDIN; UNCLASSIFIED DRUG;

EID: 10744224448     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.12.6856     Document Type: Article
Times cited : (351)

References (60)
  • 2
    • 0023177955 scopus 로고
    • Leukotrienes and lipoxins: Structures, biosynthesis, and biological effects
    • Samuelsson, B., S. E. Dahlén. J. A. Lindgren, C. A. Rouzer, and C. N. Serhan. 1987. Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science 237:1171.
    • (1987) Science , vol.237 , pp. 1171
    • Samuelsson, B.1    Dahlén, S.E.2    Lindgren, J.A.3    Rouzer, C.A.4    Serhan, C.N.5
  • 3
    • 0033590513 scopus 로고    scopus 로고
    • Treatment of asthma with drugs modifying the leukotriene pathway
    • Drazen, J. M., E. Israel, and P. M. O'Byrne. 1999. Treatment of asthma with drugs modifying the leukotriene pathway. N. Engl. J. Med. 340:197.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 197
    • Drazen, J.M.1    Israel, E.2    O'Byrne, P.M.3
  • 5
    • 0038597291 scopus 로고    scopus 로고
    • Endogenous chemical mediators in anti-inflammation and pro-resolution
    • Serhan, C. N. 2002. Endogenous chemical mediators in anti-inflammation and pro-resolution. Curr. Med. Chem. 1: 177.
    • (2002) Curr. Med. Chem. , vol.1 , pp. 177
    • Serhan, C.N.1
  • 8
    • 0034916569 scopus 로고    scopus 로고
    • Lipid mediator class switching during acute inflammation: Signals in resolution
    • Levy, B. D., C. B. Clish, B. Schmidt, K. Gronert. and C. N. Serhan. 2001. Lipid mediator class switching during acute inflammation: signals in resolution. Nat. Immunol. 2:612.
    • (2001) Nat. Immunol. , vol.2 , pp. 612
    • Levy, B.D.1    Clish, C.B.2    Schmidt, B.3    Gronert, K.4    Serhan, C.N.5
  • 9
    • 0036779617 scopus 로고    scopus 로고
    • Anti-inflammatory lipid mediators and insights into the resolution of inflammation
    • Lawrence, T., D. A. Willoughby, and D. W. Gilroy. 2002. Anti-inflammatory lipid mediators and insights into the resolution of inflammation. Nat. Rev. Immunol. 2:787.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 787
    • Lawrence, T.1    Willoughby, D.A.2    Gilroy, D.W.3
  • 10
    • 0033588034 scopus 로고    scopus 로고
    • Anti-inflammatory properties of cytochrome P450 epoxygenasederived eicosanoids
    • Node, K., Y. Huo, X. Ruan, B. Yang, M. Spiecker. K. Ley, D. C. Zeldin, and J. K. Liao. 1999. Anti-inflammatory properties of cytochrome P450 epoxygenasederived eicosanoids. Science 285:1276.
    • (1999) Science , vol.285 , pp. 1276
    • Node, K.1    Huo, Y.2    Ruan, X.3    Yang, B.4    Spiecker, M.5    Ley, K.6    Zeldin, D.C.7    Liao, J.K.8
  • 11
    • 0030736867 scopus 로고    scopus 로고
    • The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity
    • Gillmor, S. A., A. Villasenor. R. Fletterick, E. Sigal, and M. F. Browner. 1997. The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity. [Published erratum appears in 1998 Nat. Struct. Biol. 5: 242.] Nat. Struct. Biol. 4:1003.
    • (1997) Nat. Struct. Biol. , vol.4 , pp. 1003
    • Gillmor, S.A.1    Villasenor, A.2    Fletterick, R.3    Sigal, E.4    Browner, M.F.5
  • 12
    • 0031889927 scopus 로고    scopus 로고
    • Published erratum appears
    • Gillmor, S. A., A. Villasenor. R. Fletterick, E. Sigal, and M. F. Browner. 1997. The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity. [Published erratum appears in 1998 Nat. Struct. Biol. 5: 242.] Nat. Struct. Biol. 4:1003.
    • (1998) Nat. Struct. Biol. , vol.5 , pp. 242
  • 13
    • 0002591539 scopus 로고    scopus 로고
    • Update on arachidonic acid cascade: Leukotrienes and lipoxins in disease models
    • C. N. Serhan and P. A. Ward, eds. Humana, Totowa, NJ
    • Haeggström, J. Z., and C. N. Serhan. 1999. Update on arachidonic acid cascade: leukotrienes and lipoxins in disease models. In Molecular and Cellular Basis of Inflammation, C. N. Serhan and P. A. Ward, eds. Humana, Totowa, NJ, p. 51.
    • (1999) Molecular and Cellular Basis of Inflammation , pp. 51
    • Haeggström, J.Z.1    Serhan, C.N.2
  • 14
    • 0014217378 scopus 로고
    • On the specificity of the oxygenation of unsaturated fatty acids catalyzed by soybean lipoxidase
    • Hamberg, M., and B. Samuelsson. 1967. On the specificity of the oxygenation of unsaturated fatty acids catalyzed by soybean lipoxidase, J. Biol. Chem. 242:5329.
    • (1967) J. Biol. Chem. , vol.242 , pp. 5329
    • Hamberg, M.1    Samuelsson, B.2
  • 16
    • 0036669583 scopus 로고    scopus 로고
    • Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications
    • Kuhn, H., M. Walther, and R. J. Kuban. 2002. Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications. Prostaglandins Other Lipid Mediat. 68- 69:263.
    • (2002) Prostaglandins Other Lipid Mediat. , vol.68-69 , pp. 263
    • Kuhn, H.1    Walther, M.2    Kuban, R.J.3
  • 17
    • 0038013967 scopus 로고    scopus 로고
    • Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood and glial cells: Autacoids in anti-inflammation
    • Hong, S., K. Gronert, P. Devchand, R.-L. Moussignac, and C. N. Serhan. 2003. Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood and glial cells: autacoids in anti-inflammation. J. Biol. Chem. 278:14677.
    • (2003) J. Biol. Chem. , vol.278 , pp. 14677
    • Hong, S.1    Gronert, K.2    Devchand, P.3    Moussignac, R.-L.4    Serhan, C.N.5
  • 18
    • 0032006236 scopus 로고    scopus 로고
    • A specific 15-lipoxygenase inhibitor limits the progression and monocyte-macrophage enrichment of hypercholesterolemia-induced atherosclerosis in the rabbit
    • Bocan, T. M. A., W. S. Rosebury, S. B. Mueller, S. Kuchera, K. Welch, A. Daugherty, and J. A. Comicelli. 1998. A specific 15-lipoxygenase inhibitor limits the progression and monocyte-macrophage enrichment of hypercholesterolemia-induced atherosclerosis in the rabbit. Atherosclerosis 136:203
    • (1998) Atherosclerosis , vol.136 , pp. 203
    • Bocan, T.M.A.1    Rosebury, W.S.2    Mueller, S.B.3    Kuchera, S.4    Welch, K.5    Daugherty, A.6    Comicelli, J.A.7
  • 19
    • 0035951353 scopus 로고    scopus 로고
    • Inhibition of 15-lipoxygenase leads to delayed organelle degradation in the reticulocyte
    • Grüllich, C., R. M. Duvoisin. M. Wiedmann, and K. Van Leyen. 2001. Inhibition of 15-lipoxygenase leads to delayed organelle degradation in the reticulocyte. FEBS Lett. 489:51.
    • (2001) FEBS Lett. , vol.489 , pp. 51
    • Grüllich, C.1    Duvoisin, R.M.2    Wiedmann, M.3    Van Leyen, K.4
  • 22
    • 0037379738 scopus 로고    scopus 로고
    • Lipoxins: Proresolution lipid mediators in intestinal inflammation
    • Goh, J., C. Godson, H. R. Brady. and P. MacMathuna. 2003. Lipoxins: proresolution lipid mediators in intestinal inflammation. Gastroenterology 124:1043.
    • (2003) Gastroenterology , vol.124 , pp. 1043
    • Goh, J.1    Godson, C.2    Brady, H.R.3    MacMathuna, P.4
  • 23
    • 0032065589 scopus 로고    scopus 로고
    • Changes in expression of 15-lipoxygenase and prostaglandin-H synthase during differentiation of human tracheobronchial epithelial cells
    • Hill, E. M., T. Eling, and P. Nettesheim. 1998. Changes in expression of 15-lipoxygenase and prostaglandin-H synthase during differentiation of human tracheobronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 18:662.
    • (1998) Am. J. Respir. Cell Mol. Biol. , vol.18 , pp. 662
    • Hill, E.M.1    Eling, T.2    Nettesheim, P.3
  • 27
    • 0027283573 scopus 로고
    • Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins
    • Levy, B. D., M. Romano, H. A. Chapman, J. J. Reilly, J. Drazen, and C. N. Serhan. 1993. Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins. J. Clin. Invest. 92:1572.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1572
    • Levy, B.D.1    Romano, M.2    Chapman, H.A.3    Reilly, J.J.4    Drazen, J.5    Serhan, C.N.6
  • 31
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby, P. 2002. Inflammation in atherosclerosis. Nature 420:868.
    • (2002) Nature , vol.420 , pp. 868
    • Libby, P.1
  • 32
    • 0037315708 scopus 로고    scopus 로고
    • Resolution of inflammation: A new paradigm for the pathogenesis of periodontal diseases
    • Van Dyke, T. E., and C. N. Serhan. 2003. Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases. J. Dent. Res. 82:82.
    • (2003) J. Dent. Res. , vol.82 , pp. 82
    • Van Dyke, T.E.1    Serhan, C.N.2
  • 33
    • 0013660437 scopus 로고    scopus 로고
    • Lupus erythematosus: The role of adhesion molecules and local mediators
    • C. N. Serhan and P. A. Ward, eds. Humana, Totowa, NJ
    • Belmont, H. M., and S. B. Abramson. 1999. Lupus erythematosus: the role of adhesion molecules and local mediators. In Molecular and Cellular Basis of Inflammation. C. N. Serhan and P. A. Ward, eds. Humana, Totowa, NJ, p. 309.
    • (1999) Molecular and Cellular Basis of Inflammation , pp. 309
    • Belmont, H.M.1    Abramson, S.B.2
  • 34
    • 0019189630 scopus 로고
    • Release of inflammatory mediators from stimulated neutrophils
    • Weissmann, G., J. E. Smolen, and H. M. Korchak. 1980. Release of inflammatory mediators from stimulated neutrophils. N. Engl. J. Med. 303:27.
    • (1980) N. Engl. J. Med. , vol.303 , pp. 27
    • Weissmann, G.1    Smolen, J.E.2    Korchak, H.M.3
  • 35
    • 0034619970 scopus 로고    scopus 로고
    • Immunodeficiency diseases caused by defects in phagocytes
    • Lekstrom-Himes, J. A., and J. I. Gallin. 2000. Immunodeficiency diseases caused by defects in phagocytes. N. Engl. J. Med. 343:1703.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1703
    • Lekstrom-Himes, J.A.1    Gallin, J.I.2
  • 36
  • 38
    • 0026442228 scopus 로고
    • Detection of enhanced neutrophil adhesion to parainfluenza-infected airway epithelial cells using a modified myeloperoxidase assay in a microtiter format
    • Stark, J. M., A. W. van Egmond, J. J. Zimmerman, S. K. Carabell, and M. F. Tosi. 1992. Detection of enhanced neutrophil adhesion to parainfluenza-infected airway epithelial cells using a modified myeloperoxidase assay in a microtiter format. J. Virol. Methods 40:225.
    • (1992) J. Virol. Methods , vol.40 , pp. 225
    • Stark, J.M.1    Van Egmond, A.W.2    Zimmerman, J.J.3    Carabell, S.K.4    Tosi, M.F.5
  • 39
    • 0027494897 scopus 로고
    • Measurement of cutaneous microvascular exudates using Evans blue
    • Humphrey, D. M. 1993. Measurement of cutaneous microvascular exudates using Evans blue. Biotech. Histochem. 68:342.
    • (1993) Biotech. Histochem. , vol.68 , pp. 342
    • Humphrey, D.M.1
  • 42
    • 0033567662 scopus 로고    scopus 로고
    • Role of 5-lipoxygenase products in the local accumulation of neutrophils in dermal inflammation in the rabbit
    • Marleau, S., B. Fruteau de Laclos, A. B. Sanchez, P. E. Poubelle, and P. Borgeat. 1999. Role of 5-lipoxygenase products in the local accumulation of neutrophils in dermal inflammation in the rabbit. J. Immunol. 163:3349.
    • (1999) J. Immunol. , vol.163 , pp. 3349
    • Marleau, S.1    Fruteau De Laclos, B.2    Sanchez, A.B.3    Poubelle, P.E.4    Borgeat, P.5
  • 43
    • 0014327776 scopus 로고
    • Radiographic assessment of periodontal disease
    • Bjorn, H. 1968. Radiographic assessment of periodontal disease, Int. Dent. J. 18:61.
    • (1968) Int. Dent. J. , vol.18 , pp. 61
    • Bjorn, H.1
  • 44
    • 0014454186 scopus 로고
    • Radiographic assessment of marginal bone loss
    • Bjorn, H., A. Halling, and H. Thyberg. 1969. Radiographic assessment of marginal bone loss. Odontol. Revy 20:165.
    • (1969) Odontol. Revy , vol.20 , pp. 165
    • Bjorn, H.1    Halling, A.2    Thyberg, H.3
  • 45
    • 0032605457 scopus 로고    scopus 로고
    • Transcellular regulation of eicosanoid biosynthesis
    • E. A. Lianos, ed. Humana, Totowa, NJ
    • Gronert, K., C. B. Clish, M. Romano, and C. N. Serhan. 1999. Transcellular regulation of eicosanoid biosynthesis. In Eicosanoid Protocols. E. A. Lianos, ed. Humana, Totowa, NJ, p. 119.
    • (1999) Eicosanoid Protocols , pp. 119
    • Gronert, K.1    Clish, C.B.2    Romano, M.3    Serhan, C.N.4
  • 46
    • 0034712720 scopus 로고    scopus 로고
    • Lipoxin A4 analogues inhibit leukocyte recruitment to Porphyromonas gingivalis: A role for cyclooxygenase-2 and lipoxins in periodontal disease
    • Pouliot, M., C. B. Clish, N. A. Petasis, T. E. Van Dyke,. and C. N. Serhan. 2000. Lipoxin A4 analogues inhibit leukocyte recruitment to Porphyromonas gingivalis: a role for cyclooxygenase-2 and lipoxins in periodontal disease. Biochemistry 39:4761.
    • (2000) Biochemistry , vol.39 , pp. 4761
    • Pouliot, M.1    Clish, C.B.2    Petasis, N.A.3    Van Dyke, T.E.4    Serhan, C.N.5
  • 48
    • 0032952048 scopus 로고    scopus 로고
    • Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: A "stop" signaling switch for aspirin-triggered lipoxin A4
    • Levy, B. D., V. V. Fokin, J. M. Clark, M. J. O. Wakelam, N. A. Petasis, and C. N. Serhan. 1999. Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a "stop" signaling switch for aspirin-triggered lipoxin A4. FASEB J. 13:903.
    • (1999) FASEB J. , vol.13 , pp. 903
    • Levy, B.D.1    Fokin, V.V.2    Clark, J.M.3    Wakelam, M.J.O.4    Petasis, N.A.5    Serhan, C.N.6
  • 49
    • 0034599741 scopus 로고    scopus 로고
    • Activation of lipoxin A4 receptors by aspirin -triggered lipoxins and select peptides evokes ligand-specific responses in inflammation
    • Chiang, N., I. M. Fierro, K. Gronert, and C. N. Serhan. 2000. Activation of lipoxin A4 receptors by aspirin -triggered lipoxins and select peptides evokes ligand-specific responses in inflammation. J. Exp. Med. 191:1197.
    • (2000) J. Exp. Med. , vol.191 , pp. 1197
    • Chiang, N.1    Fierro, I.M.2    Gronert, K.3    Serhan, C.N.4
  • 51
    • 0021686904 scopus 로고
    • Inhibition of human natural killer cell activity by (14R,15S)-14,15-dihydroxy-5Z,8Z, 1OE, 12E-icosatetraenoic acid
    • Ramstedt. U., C. N. Serhan, U. Lundberg, H. Wigzell, and B. Samuelsson. 1984. Inhibition of human natural killer cell activity by (14R,15S)-14,15-dihydroxy-5Z,8Z, 1OE, 12E-icosatetraenoic acid. Proc. Natl. Acad Sci. USA 81:6914.
    • (1984) Proc. Natl. Acad Sci. USA , vol.81 , pp. 6914
    • Ramstedt, U.1    Serhan, C.N.2    Lundberg, U.3    Wigzell, H.4    Samuelsson, B.5
  • 52
    • 0028147706 scopus 로고
    • Stimulation of lipoxin synthesis from leukotriene A4 by endogenously formed 12-hydroperoxyeicosa-tetraenoic acid in activated human platelets
    • Edenius, C., S. Tornhamre, and J. A. Lindgren. 1994. Stimulation of lipoxin synthesis from leukotriene A4 by endogenously formed 12-hydroperoxyeicosa-tetraenoic acid in activated human platelets. Biochim. Biophys. Acta 1210:361.
    • (1994) Biochim. Biophys. Acta , vol.1210 , pp. 361
    • Edenius, C.1    Tornhamre, S.2    Lindgren, J.A.3
  • 53
    • 0034873471 scopus 로고    scopus 로고
    • Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis
    • Walther, M., I. Ivanov, G. Myagkova, and H. Kuhn. 2001. Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis. Chem. Biol. 8:779.
    • (2001) Chem. Biol. , vol.8 , pp. 779
    • Walther, M.1    Ivanov, I.2    Myagkova, G.3    Kuhn, H.4
  • 54
    • 0005893826 scopus 로고    scopus 로고
    • What is gingivitis? Current understanding of prevention, treatment, measurement, pathogenesis and relation to periodontitis
    • Van Dyke, T. E., S. Offenbacher, B. Pihlstrom, M. S. Putt, and C. Trummel. 1999. What is gingivitis? Current understanding of prevention, treatment, measurement, pathogenesis and relation to periodontitis. J. Int. Acad. Periodontol. 1:3.
    • (1999) J. Int. Acad. Periodontol. , vol.1 , pp. 3
    • Van Dyke, T.E.1    Offenbacher, S.2    Pihlstrom, B.3    Putt, M.S.4    Trummel, C.5
  • 56
    • 0032113845 scopus 로고    scopus 로고
    • Periodontal disease and mortality from all causes in the VA Dental Longitudinal Study
    • Garcia, R. I., E. A. Krall, and P. S. Vokonas. 1998. Periodontal disease and mortality from all causes in the VA Dental Longitudinal Study. Ann. Periodontol. 3:339.
    • (1998) Ann. Periodontol. , vol.3 , pp. 339
    • Garcia, R.I.1    Krall, E.A.2    Vokonas, P.S.3
  • 57
    • 0026680341 scopus 로고
    • Angioplasty triggers intracoronary leukotrienes and lipoxin A4: Impact of aspirin therapy
    • Brezinski, D. A., R. W. Nesto, and C. N. Serhan. 1992. Angioplasty triggers intracoronary leukotrienes and lipoxin A4: impact of aspirin therapy. Circulation 86:56.
    • (1992) Circulation , vol.86 , pp. 56
    • Brezinski, D.A.1    Nesto, R.W.2    Serhan, C.N.3
  • 58
    • 0037180812 scopus 로고    scopus 로고
    • Points of control in inflammation
    • Nathan, C. 2002. Points of control in inflammation. Nature 420:846.
    • (2002) Nature , vol.420 , pp. 846
    • Nathan, C.1
  • 60
    • 0028366749 scopus 로고
    • Eicosanoids in leukocyte function
    • Serhan, C. N. 1994. Eicosanoids in leukocyte function. Curr. Opin. Hematol. 1:69.
    • (1994) Curr. Opin. Hematol. , vol.1 , pp. 69
    • Serhan, C.N.1


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