First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 2b: Genetically modified source pigs

Xenotransplantation

Volumn 23, Issue 1, 2016, Pages 32-37

  Cowan, Peter J ^a   Ayares, David ^b   Wolf, Eckhard ^c   Cooper, David K C ^d  

^a ST VINCENT S HOSPITAL   (Australia)

^b REVIVICOR INC   (United States)

^c UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

genetic modification; genome editing; islet xenotransplantation; multitransgenic; site specific nuclease

Indexed keywords

ARTICLE; CLINICAL TRIAL (TOPIC); CRISPR CAS SYSTEM; DNA MODIFICATION; GENE EXPRESSION; GENETIC ENGINEERING; GRAFT REJECTION; IN VITRO STUDY; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; NONHUMAN; ORGAN DONOR; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTECTION; QUALITY CONTROL; SAFETY; TRANSGENE; TRANSGENIC PIG; WILD TYPE; XENOTRANSPLANTATION; ANIMAL; CONSENSUS DEVELOPMENT; DIABETES MELLITUS, TYPE 1; HUMAN; LEGISLATION AND JURISPRUDENCE; PIG; TRANSGENIC ANIMAL; XENOGRAFT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CLINICAL TRIALS AS TOPIC; DIABETES MELLITUS, TYPE 1; HUMANS; ISLETS OF LANGERHANS TRANSPLANTATION; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84960797761     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/xen.12224     Document Type: Article

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