Pig-to-monkey islet xenotransplantation using multi-transgenic pigs

American Journal of Transplantation

Volumn 14, Issue 10, 2014, Pages 2275-2287

  Bottino, R ^a,d   Wijkstrom, M ^b   Van Der Windt, D J ^b   Hara, H ^b   Ezzelarab, M ^b   Murase, N ^b   Bertera, S ^a   He, J ^a   Phelps, C ^c   Ayares, D ^c   Cooper, D K C ^b   Trucco, M ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c REVIVICOR INC   (United States)

^d ALLEGHENY HEALTH NETWORK   (United States)

Author keywords

islets of Langerhans; nonhuman primate; science; Translational research; xenotransplantation

Indexed keywords

C PEPTIDE; GLUCOSE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GLUCOSE BLOOD LEVEL; IMMUNOSUPPRESSIVE AGENT; MEMBRANE COFACTOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPSY; BLOOD CLOTTING TIME; COMPLEMENT ACTIVATION; CONTROLLED STUDY; DNA MODIFICATION; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; MACACA FASCICULARIS; MONONUCLEAR CELL; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; QUALITY CONTROL; RADIOIMMUNOASSAY; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TRANSGENIC PIG; XENOTRANSPLANTATION; ANALYSIS; ANIMAL; FEMALE; IMMUNOLOGY; LIVER; PANCREAS; PATHOLOGY; PIG; TRANSGENIC ANIMAL; XENOGRAFT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGENS, CD46; BLOOD GLUCOSE; CTLA-4 ANTIGEN; FEMALE; GLUCOSE; IMMUNOSUPPRESSIVE AGENTS; ISLETS OF LANGERHANS TRANSPLANTATION; LIVER; MACACA FASCICULARIS; PANCREAS; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84908163042     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12868     Document Type: Article

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