Xenografted islet cell clusters from INSLEA29Y transgenic pigs rescue diabetes and prevent immune rejection in humanized mice

Diabetes

Volumn 61, Issue 6, 2012, Pages 1527-1532

  Klymiuk, Nikolai ^a   Van Buerck, Lelia ^b   Bähr, Andrea ^a   Offers, Monika ^b   Kessler, Barbara ^a   Wuensch, Annegret ^a   Kurome, Mayuko ^a   Thormann, Michael ^a   Lochner, Katharina ^b   Nagashima, Hiroshi ^c   Herbach, Nadja ^a   Wanke, Rüdiger ^a   Seissler, Jochen ^b   Wolf, Eckhard ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c MEIJI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 2 RECEPTOR GAMMA; LEA29Y ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CELL TRANSPLANTATION; DIABETES MELLITUS; GLUCOSE HOMEOSTASIS; HUMAN; HUMAN CELL; HYPERGLYCEMIA; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RECURRENT DISEASE; XENOGRAFT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL DIFFERENTIATION; DIABETES MELLITUS, TYPE 1; GRAFT REJECTION; HYPERGLYCEMIA; INSULIN; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; PROMOTER REGIONS, GENETIC; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84861898204     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-1325     Document Type: Article

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