-
1
-
-
58149305794
-
An empirical framework for binary interactome mapping
-
K. Venkatesan, and et al. An empirical framework for binary interactome mapping Nat. Methods 6 2009 83 90
-
(2009)
Nat. Methods
, vol.6
, pp. 83-90
-
-
Venkatesan, K.1
-
2
-
-
79960990847
-
Chemical and structural lessons from recent successes in protein-protein interaction inhibition (2P2I)
-
X. Morelli, and et al. Chemical and structural lessons from recent successes in protein-protein interaction inhibition (2P2I) Curr. Opin. Chem. Biol. 15 2011 475 481
-
(2011)
Curr. Opin. Chem. Biol.
, vol.15
, pp. 475-481
-
-
Morelli, X.1
-
3
-
-
84884587933
-
IPPI-DB: A manually curated and interactive database of small non-peptide inhibitors of protein-protein interactions
-
C.M. Labbé, and et al. iPPI-DB: a manually curated and interactive database of small non-peptide inhibitors of protein-protein interactions Drug Discov. Today 18 2013 958 968
-
(2013)
Drug Discov. Today
, vol.18
, pp. 958-968
-
-
Labbé, C.M.1
-
4
-
-
84885920636
-
TIMBAL v2: Update of a database holding small molecules modulating protein-protein interactions
-
A.P. Higueruelo, and et al. TIMBAL v2: update of a database holding small molecules modulating protein-protein interactions Database (Oxford) 2013, bat039 2013
-
(2013)
Database (Oxford) 2013, bat039
-
-
Higueruelo, A.P.1
-
5
-
-
84857509304
-
Small-molecule stabilization of protein-protein interactions: An underestimated concept in drug discovery?
-
P. Thiel, and et al. Small-molecule stabilization of protein-protein interactions: an underestimated concept in drug discovery? Angew. Chem. Int. Ed. Engl. 51 2012 2012 2018
-
(2012)
Angew. Chem. Int. Ed. Engl.
, vol.51
, pp. 2012-2018
-
-
Thiel, P.1
-
6
-
-
78549274705
-
Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor
-
L.B. Sheard, and et al. Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor Nature 468 2010 400 405
-
(2010)
Nature
, vol.468
, pp. 400-405
-
-
Sheard, L.B.1
-
7
-
-
34249874926
-
Strategies to search and design stabilizers of protein-protein interactions: A feasibility study
-
P. Block, and et al. Strategies to search and design stabilizers of protein-protein interactions: a feasibility study Proteins 68 2007 170 186
-
(2007)
Proteins
, vol.68
, pp. 170-186
-
-
Block, P.1
-
8
-
-
84910596652
-
Stabilization of protein-protein interactions by small molecules
-
F. Giordanetto, and et al. Stabilization of protein-protein interactions by small molecules Drug Discov. Today 19 2014 1812 1821
-
(2014)
Drug Discov. Today
, vol.19
, pp. 1812-1821
-
-
Giordanetto, F.1
-
9
-
-
78651189765
-
On the nature of allosteric transitions: A plausible model
-
J. Monod, and et al. On the nature of allosteric transitions: a plausible model J. Mol. Biol. 12 1965 88 118
-
(1965)
J. Mol. Biol.
, vol.12
, pp. 88-118
-
-
Monod, J.1
-
11
-
-
0041312697
-
Diversity of protein-protein interactions
-
I.M.A. Nooren, and J.M. Thornton Diversity of protein-protein interactions EMBO J. 22 2003 3486 3492
-
(2003)
EMBO J.
, vol.22
, pp. 3486-3492
-
-
Nooren, I.M.A.1
Thornton, J.M.2
-
12
-
-
33744544172
-
14-3-3 proteins in cell cycle regulation
-
H. Hermeking, and A. Benzinger 14-3-3 proteins in cell cycle regulation Semin. Cancer Biol. 16 2006 183 192
-
(2006)
Semin. Cancer Biol.
, vol.16
, pp. 183-192
-
-
Hermeking, H.1
Benzinger, A.2
-
13
-
-
0032491581
-
Complementation of the Saccharomyces cerevisiae plasma membrane H+-ATPase by a plant H+-ATPase generates a highly abundant fusicoccin binding site
-
M. Piotrowski, and et al. Complementation of the Saccharomyces cerevisiae plasma membrane H+-ATPase by a plant H+-ATPase generates a highly abundant fusicoccin binding site J. Biol. Chem. 273 1998 30018 30023
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30018-30023
-
-
Piotrowski, M.1
-
14
-
-
60149087610
-
A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A
-
C. Ottmann, and et al. A structural rationale for selective stabilization of anti-tumor interactions of 14-3-3 proteins by cotylenin A J. Mol. Biol. 386 2009 913 919
-
(2009)
J. Mol. Biol.
, vol.386
, pp. 913-919
-
-
Ottmann, C.1
-
15
-
-
77953106214
-
Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions
-
R. Rose, and et al. Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions Angew. Chem. Int. Ed Engl. 49 2010 4129 4132
-
(2010)
Angew. Chem. Int. Ed Engl.
, vol.49
, pp. 4129-4132
-
-
Rose, R.1
-
16
-
-
84861134839
-
An optimised small-molecule stabiliser of the 14-3-3-PMA2 protein-protein interaction
-
A. Richter, and et al. An optimised small-molecule stabiliser of the 14-3-3-PMA2 protein-protein interaction Chem. Weinh. Bergstr. Ger. 18 2012 6520 6527
-
(2012)
Chem. Weinh. Bergstr. Ger.
, vol.18
, pp. 6520-6527
-
-
Richter, A.1
-
17
-
-
84884654621
-
Stabilization of physical RAF/14-3-3 interaction by cotylenin A as treatment strategy for RAS mutant cancers
-
M. Molzan, and et al. Stabilization of physical RAF/14-3-3 interaction by cotylenin A as treatment strategy for RAS mutant cancers ACS Chem. Biol. 8 2013 1869 1875
-
(2013)
ACS Chem. Biol.
, vol.8
, pp. 1869-1875
-
-
Molzan, M.1
-
18
-
-
84878442899
-
Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface
-
I.J. De Vries-van Leeuwen, and et al. Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface Proc. Natl. Acad. Sci. U. S. A. 110 2013 8894 8899
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 8894-8899
-
-
De Vries-Van Leeuwen, I.J.1
-
19
-
-
84876472566
-
A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface
-
C. Anders, and et al. A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface Chem. Biol. 20 2013 583 593
-
(2013)
Chem. Biol.
, vol.20
, pp. 583-593
-
-
Anders, C.1
-
20
-
-
61649122140
-
Intracellular traffic of the K+ channels TASK-1 and TASK-3: Role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins
-
M. Zuzarte, and et al. Intracellular traffic of the K+ channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins J. Physiol. 587 2009 929 952
-
(2009)
J. Physiol.
, vol.587
, pp. 929-952
-
-
Zuzarte, M.1
-
21
-
-
33745674468
-
Drug discovery in the ubiquitin-proteasome system
-
G. Nalepa, and et al. Drug discovery in the ubiquitin-proteasome system Nat. Rev. Drug Discov. 5 2006 596 613
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 596-613
-
-
Nalepa, G.1
-
22
-
-
79959656754
-
An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme
-
D.F. Ceccarelli, and et al. An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme Cell 145 2011 1075 1087
-
(2011)
Cell
, vol.145
, pp. 1075-1087
-
-
Ceccarelli, D.F.1
-
23
-
-
84896639811
-
E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin
-
H. Huang, and et al. E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin Nat. Chem. Biol. 10 2014 156 163
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 156-163
-
-
Huang, H.1
-
24
-
-
0031982629
-
ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6
-
S. Frank, and et al. ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6 J. Biol. Chem. 273 1998 23 27
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 23-27
-
-
Frank, S.1
-
26
-
-
34547130929
-
Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein-protein complexes
-
J. Viaud, and et al. Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein-protein complexes Proc. Natl. Acad. Sci. U. S. A. 104 2007 10370 10375
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 10370-10375
-
-
Viaud, J.1
-
27
-
-
0034691131
-
The histone deacetylase-3 complex contains nuclear receptor corepressors
-
Y.D. Wen, and et al. The histone deacetylase-3 complex contains nuclear receptor corepressors Proc. Natl. Acad. Sci. U. S. A. 97 2000 7202 7207
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 7202-7207
-
-
Wen, Y.D.1
-
28
-
-
84855984763
-
Structure of HDAC3 bound to co-repressor and inositol tetraphosphate
-
P.J. Watson, and et al. Structure of HDAC3 bound to co-repressor and inositol tetraphosphate Nature 481 2012 335 340
-
(2012)
Nature
, vol.481
, pp. 335-340
-
-
Watson, P.J.1
-
30
-
-
34247219263
-
Mechanism of auxin perception by the TIR1 ubiquitin ligase
-
X. Tan, and et al. Mechanism of auxin perception by the TIR1 ubiquitin ligase Nature 446 2007 640 645
-
(2007)
Nature
, vol.446
, pp. 640-645
-
-
Tan, X.1
-
31
-
-
84882912908
-
Molecular mechanism for plant steroid receptor activation by somatic embryogenesis co-receptor kinases
-
J. Santiago, and et al. Molecular mechanism for plant steroid receptor activation by somatic embryogenesis co-receptor kinases Science 341 2013 889 892
-
(2013)
Science
, vol.341
, pp. 889-892
-
-
Santiago, J.1
-
32
-
-
84857254665
-
Small-conductance Ca2+-activated K+ channels: Form and function
-
J.P. Adelman, and et al. Small-conductance Ca2+-activated K+ channels: form and function Annu. Rev. Physiol. 74 2012 245 269
-
(2012)
Annu. Rev. Physiol.
, vol.74
, pp. 245-269
-
-
Adelman, J.P.1
-
33
-
-
77649191092
-
Common variants in KCNN3 are associated with lone atrial fibrillation
-
P.T. Ellinor, and et al. Common variants in KCNN3 are associated with lone atrial fibrillation Nat. Genet. 42 2010 240 244
-
(2010)
Nat. Genet.
, vol.42
, pp. 240-244
-
-
Ellinor, P.T.1
-
34
-
-
34547985303
-
Functions of SK channels in central neurons
-
E.S.L. Faber, and P. Sah Functions of SK channels in central neurons Clin. Exp. Pharmacol. Physiol. 34 2007 1077 1083
-
(2007)
Clin. Exp. Pharmacol. Physiol.
, vol.34
, pp. 1077-1083
-
-
Faber, E.S.L.1
Sah, P.2
-
35
-
-
84866074628
-
2+-activated potassium channels
-
2+-activated potassium channels Nat. Commun. 3 2012 1021
-
(2012)
Nat. Commun.
, vol.3
, pp. 1021
-
-
Zhang, M.1
-
36
-
-
84875242563
-
2+-sensing and SK channel activation
-
2+-sensing and SK channel activation Proc. Natl. Acad. Sci. U. S. A. 110 2013 4828 4833
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 4828-4833
-
-
Zhang, M.1
-
37
-
-
33745087154
-
Survivin, a cancer target with an emerging role in normal adult tissues
-
S. Fukuda, and L.M. Pelus Survivin, a cancer target with an emerging role in normal adult tissues Mol. Cancer Ther. 5 2006 1087 1098
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 1087-1098
-
-
Fukuda, S.1
Pelus, L.M.2
-
38
-
-
84883489537
-
Design, synthesis and biological studies of survivin dimerization modulators that prolong mitotic cycle
-
S.N. Chettiar, and et al. Design, synthesis and biological studies of survivin dimerization modulators that prolong mitotic cycle Bioorg. Med. Chem. Lett. 23 2013 5429 5433
-
(2013)
Bioorg. Med. Chem. Lett.
, vol.23
, pp. 5429-5433
-
-
Chettiar, S.N.1
-
39
-
-
34247868131
-
Discovery of a novel small molecule binding site of human survivin
-
M.D. Wendt, and et al. Discovery of a novel small molecule binding site of human survivin Bioorg. Med. Chem. Lett. 17 2007 3122 3129
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 3122-3129
-
-
Wendt, M.D.1
-
40
-
-
0026448670
-
The capture of a DNA double helix by an ATP-dependent protein clamp: A key step in DNA transport by type II DNA topoisomerases
-
J. Roca, and J.C. Wang The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases Cell 71 1992 833 840
-
(1992)
Cell
, vol.71
, pp. 833-840
-
-
Roca, J.1
Wang, J.C.2
-
41
-
-
0032890136
-
Dexrazoxane (ICRF-187)
-
G. Weiss, and et al. Dexrazoxane (ICRF-187) Gen. Pharmacol. 32 1999 155 158
-
(1999)
Gen. Pharmacol.
, vol.32
, pp. 155-158
-
-
Weiss, G.1
-
42
-
-
0028810791
-
A QSAR study comparing the cytotoxicity and DNA topoisomerase II inhibitory effects of bisdioxopiperazine analogs of ICRF-187 (dexrazoxane)
-
B.B. Hasinoff, and et al. A QSAR study comparing the cytotoxicity and DNA topoisomerase II inhibitory effects of bisdioxopiperazine analogs of ICRF-187 (dexrazoxane) Biochem. Pharmacol. 50 1995 953 958
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 953-958
-
-
Hasinoff, B.B.1
-
43
-
-
0141591551
-
Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
-
S. Classen, and et al. Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187 Proc. Natl. Acad. Sci. U. S. A. 100 2003 10629 10634
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 10629-10634
-
-
Classen, S.1
-
44
-
-
0029062667
-
Structure of a complex of two plasma proteins: Transthyretin and retinol-binding protein
-
H.L. Monaco, and et al. Structure of a complex of two plasma proteins: transthyretin and retinol-binding protein Science 268 1995 1039 1041
-
(1995)
Science
, vol.268
, pp. 1039-1041
-
-
Monaco, H.L.1
-
45
-
-
0036527699
-
Therapeutic strategies for human amyloid diseases
-
J.C. Sacchettini, and J.W. Kelly Therapeutic strategies for human amyloid diseases Nat. Rev. Drug Discov. 1 2002 267 275
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 267-275
-
-
Sacchettini, J.C.1
Kelly, J.W.2
-
46
-
-
84862234023
-
Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade
-
C.E. Bulawa, and et al. Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade Proc. Natl. Acad. Sci. U. S. A. 109 2012 9629 9634
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 9629-9634
-
-
Bulawa, C.E.1
-
47
-
-
84889570600
-
Influenza virus nucleoprotein: Structure, RNA binding, oligomerization and antiviral drug target
-
S. Chenavas, and et al. Influenza virus nucleoprotein: structure, RNA binding, oligomerization and antiviral drug target Future Microbiol. 8 2013 1537 1545
-
(2013)
Future Microbiol.
, vol.8
, pp. 1537-1545
-
-
Chenavas, S.1
-
48
-
-
80053089237
-
Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers
-
S.W. Gerritz, and et al. Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers Proc. Natl. Acad. Sci. U. S. A. 108 2011 15366 15371
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 15366-15371
-
-
Gerritz, S.W.1
-
49
-
-
58749094954
-
Targeting Mdm2 and Mdmx in cancer therapy: Better living through medicinal chemistry?
-
M. Wade, and G.M. Wahl Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry? Mol. Cancer Res. 7 2009 1 11
-
(2009)
Mol. Cancer Res.
, vol.7
, pp. 1-11
-
-
Wade, M.1
Wahl, G.M.2
-
50
-
-
84863966819
-
Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization
-
B. Graves, and et al. Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization Proc. Natl. Acad. Sci. U. S. A. 109 2012 11788 11793
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 11788-11793
-
-
Graves, B.1
-
51
-
-
84862901143
-
Small-molecule modulators of c-Myc/Max and Max/Max interactions
-
T. Berg Small-molecule modulators of c-Myc/Max and Max/Max interactions Curr. Top. Microbiol. Immunol. 348 2011 139 149
-
(2011)
Curr. Top. Microbiol. Immunol.
, vol.348
, pp. 139-149
-
-
Berg, T.1
-
52
-
-
33746239002
-
Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules
-
A. Kiessling, and et al. Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules Chem. Biol. 13 2006 745 751
-
(2006)
Chem. Biol.
, vol.13
, pp. 745-751
-
-
Kiessling, A.1
-
53
-
-
69549124720
-
Stabilizers of the Max homodimer identified in virtual ligand screening inhibit Myc function
-
H. Jiang, and et al. Stabilizers of the Max homodimer identified in virtual ligand screening inhibit Myc function Mol. Pharmacol. 76 2009 491 502
-
(2009)
Mol. Pharmacol.
, vol.76
, pp. 491-502
-
-
Jiang, H.1
-
54
-
-
0031045565
-
PCNA: Structure, functions and interactions
-
Z. Kelman PCNA: structure, functions and interactions Oncogene 14 1997 629 640
-
(1997)
Oncogene
, vol.14
, pp. 629-640
-
-
Kelman, Z.1
-
55
-
-
84861428331
-
Small-molecule targeting of proliferating cell nuclear antigen chromatin association inhibits tumor cell growth
-
Z. Tan, and et al. Small-molecule targeting of proliferating cell nuclear antigen chromatin association inhibits tumor cell growth Mol. Pharmacol. 81 2012 811 819
-
(2012)
Mol. Pharmacol.
, vol.81
, pp. 811-819
-
-
Tan, Z.1
-
56
-
-
13844316580
-
Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design
-
G. Kontopidis, and et al. Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design Proc. Natl. Acad. Sci. U. S. A. 102 2005 1871 1876
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 1871-1876
-
-
Kontopidis, G.1
-
57
-
-
43049092564
-
S100A4: A common mediator of epithelial-mesenchymal transition, fibrosis and regeneration in diseases?
-
M. Schneider, and et al. S100A4: a common mediator of epithelial-mesenchymal transition, fibrosis and regeneration in diseases? J. Mol. Med. Berl. Ger. 86 2008 507 522
-
(2008)
J. Mol. Med. Berl. Ger.
, vol.86
, pp. 507-522
-
-
Schneider, M.1
-
58
-
-
77952724647
-
Phenothiazines inhibit S100A4 function by inducing protein oligomerization
-
V.N. Malashkevich, and et al. Phenothiazines inhibit S100A4 function by inducing protein oligomerization Proc. Natl. Acad. Sci. U. S. A. 107 2010 8605 8610
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 8605-8610
-
-
Malashkevich, V.N.1
-
59
-
-
38349151537
-
A biosensor of S100A4 metastasis factor activation: Inhibitor screening and cellular activation dynamics
-
S.C. Garrett, and et al. A biosensor of S100A4 metastasis factor activation: inhibitor screening and cellular activation dynamics Biochemistry 47 2008 986 996
-
(2008)
Biochemistry
, vol.47
, pp. 986-996
-
-
Garrett, S.C.1
-
60
-
-
0142058174
-
Anti-TNF-alpha therapies: The next generation
-
M.A. Palladino, and et al. Anti-TNF-alpha therapies: the next generation Nat. Rev. Drug Discov. 2 2003 736 746
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 736-746
-
-
Palladino, M.A.1
-
61
-
-
27744586067
-
Small-molecule inhibition of TNF-alpha
-
M.M. He, and et al. Small-molecule inhibition of TNF-alpha Science 310 2005 1022 1025
-
(2005)
Science
, vol.310
, pp. 1022-1025
-
-
He, M.M.1
-
63
-
-
79961092776
-
Small molecule inhibition of the TNF family cytokine CD40 ligand through a subunit fracture mechanism
-
L.F. Silvian, and et al. Small molecule inhibition of the TNF family cytokine CD40 ligand through a subunit fracture mechanism ACS Chem. Biol. 6 2011 636 647
-
(2011)
ACS Chem. Biol.
, vol.6
, pp. 636-647
-
-
Silvian, L.F.1
-
64
-
-
0017757557
-
Structure of the tubulin dimer
-
R.F. Ludueńa, and et al. Structure of the tubulin dimer J. Biol. Chem. 252 1977 7006 7014
-
(1977)
J. Biol. Chem.
, vol.252
, pp. 7006-7014
-
-
Ludueńa, R.F.1
-
65
-
-
1942438028
-
Microtubules as a target for anticancer drugs
-
M.A. Jordan, and L. Wilson Microtubules as a target for anticancer drugs Nat. Rev. Cancer 4 2004 253 265
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 253-265
-
-
Jordan, M.A.1
Wilson, L.2
-
66
-
-
84901362834
-
High-resolution microtubule structures reveal the structural transitions in αβ-tubulin upon GTP hydrolysis
-
G.M. Alushin, and et al. High-resolution microtubule structures reveal the structural transitions in αβ-tubulin upon GTP hydrolysis Cell 157 2014 1117 1129
-
(2014)
Cell
, vol.157
, pp. 1117-1129
-
-
Alushin, G.M.1
-
67
-
-
0028960506
-
Amyotrophic lateral sclerosis: Recent insights from genetics and transgenic mice
-
R.H. Brown Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice Cell 80 1995 687 692
-
(1995)
Cell
, vol.80
, pp. 687-692
-
-
Brown, R.H.1
-
68
-
-
14844361966
-
Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation
-
S.S. Ray, and et al. Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation Proc. Natl. Acad. Sci. U. S. A. 102 2005 3639 3644
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 3639-3644
-
-
Ray, S.S.1
-
69
-
-
84877751338
-
Ligand binding and aggregation of pathogenic SOD1
-
G.S.A. Wright, and et al. Ligand binding and aggregation of pathogenic SOD1 Nat. Commun. 4 2013 1758
-
(2013)
Nat. Commun.
, vol.4
, pp. 1758
-
-
Wright, G.S.A.1
-
70
-
-
0012473279
-
The nuclear receptor superfamily: The second decade
-
D.J. Mangelsdorf, and et al. The nuclear receptor superfamily: the second decade Cell 83 1995 835 839
-
(1995)
Cell
, vol.83
, pp. 835-839
-
-
Mangelsdorf, D.J.1
-
71
-
-
77954387100
-
A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor
-
A. Le Maire, and et al. A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor Nat. Struct. Mol. Biol. 17 2010 801 807
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 801-807
-
-
Le Maire, A.1
-
72
-
-
8844262660
-
Principles for modulation of the nuclear receptor superfamily
-
H. Gronemeyer, and et al. Principles for modulation of the nuclear receptor superfamily Nat. Rev. Drug Discov. 3 2004 950 964
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 950-964
-
-
Gronemeyer, H.1
-
73
-
-
0024442393
-
A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin
-
J.J. Siekierka, and et al. A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin Nature 341 1989 755 757
-
(1989)
Nature
, vol.341
, pp. 755-757
-
-
Siekierka, J.J.1
-
74
-
-
82755189535
-
The G46S-hPAH mutant protein: A model to study the rescue of aggregation-prone PKU mutations by chaperones
-
J. Leandro, and et al. The G46S-hPAH mutant protein: a model to study the rescue of aggregation-prone PKU mutations by chaperones Mol. Genet. Metab. 104 Suppl. 2011 40 44
-
(2011)
Mol. Genet. Metab.
, vol.104
, pp. 40-44
-
-
Leandro, J.1
-
75
-
-
33846701051
-
Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+-ATPase by combining X-ray crystallography and electron cryomicroscopy
-
C. Ottmann, and et al. Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+-ATPase by combining X-ray crystallography and electron cryomicroscopy Mol. Cell 25 2007 427 440
-
(2007)
Mol. Cell
, vol.25
, pp. 427-440
-
-
Ottmann, C.1
-
76
-
-
0037416221
-
Structural view of a fungal toxin acting on a 14-3-3 regulatory complex
-
M. Würtele, and et al. Structural view of a fungal toxin acting on a 14-3-3 regulatory complex EMBO J. 22 2003 987 994
-
(2003)
EMBO J.
, vol.22
, pp. 987-994
-
-
Würtele, M.1
-
78
-
-
0346243924
-
Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
-
L. Renault, and et al. Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor Nature 426 2003 525 530
-
(2003)
Nature
, vol.426
, pp. 525-530
-
-
Renault, L.1
-
79
-
-
19544379019
-
The F-box protein TIR1 is an auxin receptor
-
N. Dharmasiri, and et al. The F-box protein TIR1 is an auxin receptor Nature 435 2005 441 445
-
(2005)
Nature
, vol.435
, pp. 441-445
-
-
Dharmasiri, N.1
-
80
-
-
0035869056
-
BRI1 is a critical component of a plasma-membrane receptor for plant steroids
-
Z.Y. Wang, and et al. BRI1 is a critical component of a plasma-membrane receptor for plant steroids Nature 410 2001 380 383
-
(2001)
Nature
, vol.410
, pp. 380-383
-
-
Wang, Z.Y.1
|