Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 6, 2005, Pages 1871-1876

  Kontopidis, George ^a   Wu, Su Ying ^b   Zheleva, Daniella I ^a   Taylor, Paul ^b   McInnes, Campbell ^a   Lane, David P ^a   Fischer, Peter M ^a   Walkinshaw, Malcolm D ^b  

^a Cydacel Limited   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Interaction; p21; Protein; Structure; X ray

Indexed keywords

ADAPTOR PROTEIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLINE; PROTEIN P21;

ARTICLE; BINDING COMPETITION; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DNA REPLICATION; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SURFACE PROPERTY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CELL CYCLE PROTEINS; CRYSTALLOGRAPHY, X-RAY; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; HUMANS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN STRUCTURE, QUATERNARY; SEQUENCE ALIGNMENT;

EID: 13844316580     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0406540102     Document Type: Article

References (36)

1. Prelich, G., Kostura, M., Marshak, D. R., Mathews, M. B. & Stillman. B. (1987) Nature 326, 471-475.
2. Krishna, T. S. R., Kong, X. P., Gary, S., Burgers, P. M. & Kuriyan, J. (1994) Cell 79, 1233-1243.
3. Bowman, G. D., O'Donnell, M. & Kuriyan, J. (2004) Nature 429, 724-730.
4. Warbrick, E. (2000) BioEssays 22, 997-1006.
5. Paunesku, T., Mittal, S., Protic, M., Oryhon, J., Korolev, S. V., Joachimiak, A. & Woloschak, G. E. (2001) Int. J Radiat. Biol. 77, 1007-1021.
6. Sakakura, C., Hagiwara, A., Tsujimoto, H., Ozaki, K., Sakakibara, T., Oyama, T., Ogaki, M. & Takahashi, T. (1994) Br. J. Cancer 70, 1060-1066.
7. Maeshima, Y., Kashihara, N., Sugiyama, H., Makino, H. & Ota, Z. (1996) J. Am. Soc. Nephrol 7, 2219-2229.
8. Morita, Y., Kashihara, N., Yamamura, M., Okamoto, H., Harada, S., Maeshima, Y., Okamoto, K. & Makino, H. (1997) Arthritis Rheum. 40, 1292-1297.
9. Cartel, A. L. & Tyner, A. L. (2002) Mol. Cancer Ther. 1, 639-649.
10. Chen, J. J., Peters, R., Saha, P., Lee, P., Theodoras, A., Pagano, M., Wagner, G. & Dutta, A. (1996) Nucleic Acids Res. 24, 1727-1733.
11. Fotedar, R., Fitzgerald, P., Rousselle, T., Cannella, D., Doree, M., Messier, H. & Fotedar, A. (1996) Oncogene 12, 2155-2164.
12. Gulbis, J. M., Kelman, Z., Hurwitz, J., O'Donnell, M. & Kuriyan, J. (1996) Cell 87, 297-306.
13. Goubin, F. & Ducommun, B. (1995) Oncogene 10, 2281-2287.
14. Xiong, Y., Zhang, H. & Beach, D. (1993) Genes Dev. 7, 1572-1583.
15. Xiong, Y., Zhang, H. & Beach, D. (1992) Cell 71, 505-514.
16. Tsurimoto, T. (1998) Biochim. Biophys. Acta 1443, 23-39.
17. Fischer, P. M., Krausz, E. & Lane, D. P. (2001) Bioconjugate Chem. 12, 825-841.
18. Warbrick, E., Lane, D. P., Glover, D. M. & Cox, L. S. (1995) Curr. Biol. 5, 275-282.
19. Ball, K. L., Lain, S., Fahraeus, R., Smythe, C. & Lane, D. P. (1997) Curr. Biol. 7, 71-80.
20. Fahraeus, R., Paramio, J. M., Ball, K. L., Lain, S. & Lane, D. P. (1996) Curr. Biol. 6, 84-91.
21. Kontopidis, G., Andrews, M. J. I., McInnes, C., Cowan, A., Powers, H., Innes, L., Plater, A., Griffiths, G., Paterson, D., Zheleva, D. I., et al. (2003) Structure (London) 11, 1537-1546.
22. Zheleva, D. I., McInnes, C., Gavine, A. L., Zhelev, N. Z., Fischer, P. M. & Lane, D. P. (2002) J. Pept. Res. 60, 257-270.
23. Zheleva, D. I., Zhelev, N. Z., Fischer, P. M., Duff, S. V., Warbrick, E., Blake, D. G. & Lane, D. P. (2000) Biochemistry 39, 7388-7397.
24. Chan, A. W. E. & White, A., eds. (2000) Fmoc Solid Phase Peptide Synthesis: A Practical Approach (Oxford Univ. Press, Oxford).
25. Otwinowski, Z. & Minor, W. (1997) Methods Enzymol. 276, 307-326.
26. Vagin, A. & Teplyakov, A. (1997) J. Appl. Crystallogr. 30, 1022-1025.
27. Murshudov, G. N., Vagin, A. A. & Dodson, E. J. (1997) Acta Crystallogr. D 53, 240-255.
28. Chapados, B. R., Hosfield, D. J., Man, S., Qiu, J. Z., Yelent, B., Shen, B. H. & Tainer, J. A. (2004) Cell 116, 39-50.
29. Fischer, P. M., Zheleva, D. I., McInnes, C., Gavine, A., Zhelev, N. Z. & Lane, D. P. (2001) Clin. Cancer Res. 7, 824.
30. Matsuoka, S., Yamaguchi, M. & Matsukage, A. (1994) J. Biol. Chem. 269, 11030-11036.
31. Cox, L. S. (1997) Trends Cell Biol. 7, 493-498.
32. McInnes, C., Andrews, M. J., Zheleva, D. I., Lane, D. P. & Fischer, P. M. (2003) Curr. Med. Chem. Anti-Cancer Agents 3, 57-69.
33. Scott, M. T., Morrice, N. & Ball, K. L. (2000) J. Biol. Chem. 275, 11529-11537.
34. Ando, T., Kawabe, T., Ohara, H., Ducommun, B., Itoh, M. & Okamoto, T. (2001) J. Biol. Chem. 276, 42971-42977.
35. Koundrioukoff, S., Jonsson, Z. O., Hasan, S., de Jong, R. N., van der Vliet, P. C., Hottiger, M. O. & Hubscher, U. (2000) J. Biol. Chem. 275, 22882-22887.
36. Rossig, L., Jadidi, A. S., Urbich, C., Badorff, C., Zeiher, A. M. & Dimmeler, S. (2001) Mol. Cell. Biol. 21, 5644-5657.