Phenothiazines inhibit S100A4 function by inducing protein oligomerization

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 19, 2010, Pages 8605-8610

  Malashkevich, Vladimir N ^a   Dulyaninova, Natalya G ^a   Ramagopal, Udupi A ^a   Liriano, Melissa A ^b   Varney, Kristen M ^b   Knight, David ^a,c   Brenowitz, Michael ^a   Weber, David J ^b   Almo, Steven C ^a   Bresnick, Anne R ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c University of Bath   (United Kingdom)

Author keywords

Calcium; Metastasis; NMR; Small molecule inhibitor; X ray crystallography

Indexed keywords

CALVASCULIN; MYOSIN IIA; PROCHLORPERAZINE; TRIFLUOPERAZINE;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; HYDROPHOBICITY; MOLECULAR INTERACTION; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE;

CALCIUM; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; NONMUSCLE MYOSIN TYPE IIA; PROCHLORPERAZINE; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; S100 PROTEINS; TRIFLUOPERAZINE;

EID: 77952724647     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0913660107     Document Type: Article

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