Effects of cigarette smoke, cessation, and switching to two heat-not-burn tobacco products on lung lipid metabolism in C57BL/6 and Apoe-/- mice-an integrative systems toxicology analysis

Toxicological Sciences

Volumn 149, Issue 2, 2016, Pages 441-457

  Titz, Bjoern ^a   Boué, Stéphanie ^a   Phillips, Blaine ^a   Talikka, Marja ^a   Vihervaara, Terhi ^b   Schneider, Thomas ^a   Nury, Catherine ^a   Elamin, Ashraf ^a   Guedj, Emmanuel ^a   Peck, Michael J ^a   Schlage, Walter K ^a   Cabanski, Maciej ^a,c   Leroy, Patrice ^a   Vuillaume, Gregory ^a   Martin, Florian ^a   Ivanov, Nikolai V ^a   Veljkovic, Emilija ^a   Ekroos, Kim ^b   Laaksonen, Reijo ^b   Vanscheeuwijck, Patrick ^a   Peitsch, Manuel C ^a   Hoeng, Julia ^a   more..

^a PHILIP MORRIS PRODUCTS S A   (Switzerland)

^b Zora Biosciences Oy   (Finland)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

lipidomics; Modified risk tobacco products; quantitative proteomics; systems toxicology

Indexed keywords

APOLIPOPROTEIN E; CERAMIDE; CIGARETTE SMOKE; ICOSANOID; LIPID; NICOTINE; PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN; SURFACTANT; PROTEOME; SMOKE; SPHINGOLIPID;

AEROSOL; ALCOHOL ABSTINENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; LIPID METABOLISM; LIPIDOMICS; MODIFIED RISK TOBACCO PRODUCT; MOUSE; NONHUMAN; PROTEIN LIPID INTERACTION; PROTEOMICS; SPHINGOLIPID METABOLISM; TOBACCO; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; LUNG; METABOLISM; OXIDATIVE STRESS; PHYSIOLOGY; SMOKE; TOXICITY;

ANIMALS; APOLIPOPROTEINS E; EICOSANOIDS; FEMALE; LIPID METABOLISM; LUNG; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PROTEOME; SMOKE; SPHINGOLIPIDS; TOBACCO;

EID: 84960131851     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfv244     Document Type: Article

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