Cigarette smoke induces molecular responses in respiratory tissues of ApoE-/- mice that are progressively deactivated upon cessation

Toxicology

Volumn 314, Issue 1, 2013, Pages 112-124

  Boué, Stéphanie ^a   De León, Héctor ^a   Schlage, Walter K ^a,b   Peck, Michael J ^a   Weiler, Horst ^b   Berges, An ^a   Vuillaume, Grégory ^a   Martin, Florian ^a   Friedrichs, Baerbel ^b   Lebrun, Stefan ^a   Meurrens, Kris ^a   Schracke, Nadine ^b   Moehring, Michaela ^b   Steffen, Yvonne ^b   Schueller, Jutta ^b   Vanscheeuwijck, Patrick ^a,b   Peitsch, Manuel C ^a   Hoeng, Julia ^a  

^a PHILIP MORRIS PRODUCTS S A   (Switzerland)

^b Philip Morris Research Laboratories GmbH   (Germany)

Author keywords

BALF; Genome wide expression; Inflammation; Smoking; Smoking cessation

Indexed keywords

APOENZYME; CIGARETTE SMOKE; APOLIPOPROTEIN E; BIOLOGICAL MARKER; NICOTINE; PASSIVE SMOKING; RNA; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME INACTIVATION; FEMALE; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; INFLAMMATION; INFLAMMATORY CELL; LUNG LAVAGE; LUNG PARENCHYMA; MOUSE; NONHUMAN; NOSE MUCOSA; PRIORITY JOURNAL; SMOKING CESSATION; AIRWAY REMODELING; ANIMAL; BIOSYNTHESIS; DENDRITIC CELL; DRUG EFFECTS; FLOW CYTOMETRY; GENE EXPRESSION; GENETICS; ISOLATION AND PURIFICATION; KNOCKOUT MOUSE; LUNG; METABOLISM; PASSIVE SMOKING; PATHOLOGY; PHYSIOLOGY; PREGNANCY; RESPIRATORY SYSTEM; RESPIRATORY TRACT MUCOSA; SIGNAL TRANSDUCTION; SMOKING; URINE;

MURINAE; MUS;

AIRWAY REMODELING; ANIMALS; APOLIPOPROTEINS E; BIOLOGICAL MARKERS; BRONCHOALVEOLAR LAVAGE FLUID; DENDRITIC CELLS; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; LUNG; MICE; MICE, KNOCKOUT; NICOTINE; PREGNANCY; RESPIRATORY MUCOSA; RESPIRATORY SYSTEM; RNA; SIGNAL TRANSDUCTION; SMOKING; SMOKING CESSATION; TOBACCO SMOKE POLLUTION; TRANSCRIPTOME;

EID: 84886257013     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.09.013     Document Type: Article

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