ER Adaptor SCAP Translocates and Recruits IRF3 to Perinuclear Microsome Induced by Cytosolic Microbial DNAs

PLoS Pathogens

Volumn 12, Issue 2, 2016, Pages

  Chen, Wei ^a,b   Li, Senlin ^a   Yu, Huansha ^a   Liu, Xing ^a   Huang, Lulu ^a   Wang, Qiang ^a   Liu, Heng ^a   Cui, Ye ^a   Tang, Yijun ^a   Zhang, Peng ^c   Wang, Chen ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SHENZHEN UNIVERSITY   (China)

^c TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BETA INTERFERON; INTERFERON REGULATORY FACTOR 3; SREBP CLEAVAGE ACTIVATING PROTEIN; STING PROTEIN; TANK BINDING KINASE 1; UNCLASSIFIED DRUG; DNA; INTERFERON; IRF3 PROTEIN, MOUSE; MEMBRANE PROTEIN; SIGNAL PEPTIDE; SREBP CLEAVAGE-ACTIVATING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; INNATE IMMUNITY; LISTERIA MONOCYTOGENES; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; VIRUS INFECTION; ANIMAL; C57BL MOUSE; CYTOSOL; GENETICS; GOLGI COMPLEX; METABOLISM; MICROSOME; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; CYTOSOL; DNA; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; INTERFERON REGULATORY FACTOR-3; INTERFERONS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE, INBRED C57BL; MICROSOMES; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 84959493120     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005462     Document Type: Article

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