SCOPUS 정보 검색 플랫폼

Volumn 11, Issue 6, 2016, Pages 612-619

Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme

(16) Lauro, Gianluigi a Tortorella, Paolo b Bertamino, Alessia a Ostacolo, Carmine c Koeberle, Andreas d Fischer, Katrin d Bruno, Ines a Terracciano, Stefania a Gomez Monterrey, Isabel Maria c Tauro, Marilena b Loiodice, Fulvio b Novellino, Ettore c Riccio, Raffaele a Werz, Oliver d Campiglia, Pietro a Bifulco, Giuseppe a

a UNIVERSITY OF SALERNO (Italy)

b UNIVERSITY OF BARI (Italy)

c UNIVERSITY OF NAPLES FEDERICO II (Italy)

d FRIEDRICH SCHILLER UNIVERSITY JENA (Germany)

Author keywords

inflammation; medicinal chemistry; molecular modelling; prostaglandins; structure activity relationships

Indexed keywords

ANTINEOPLASTIC AGENT; BENZAMIDE DERIVATIVE; BIPHENYL DERIVATIVE; CYCLOOXYGENASE 1; N-(2,3-DIHYDROXYPHENYL)-4-BIPHENYLSULFONAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR; SULFONAMIDE;

HUMAN; METABOLISM; MOLECULAR DOCKING; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS; BENZAMIDES; BIPHENYL COMPOUNDS; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; CYCLOOXYGENASE 1; CYCLOOXYGENASE INHIBITORS; HUMANS; MOLECULAR DOCKING SIMULATION; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 84959387319 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201500598 Document Type: Article

Times cited : (18)

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