Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice

Nature Neuroscience

Volumn 19, Issue 4, 2016, Pages 623-633

  Langfelder, Peter ^a   Cantle, Jeffrey P ^a,b,c   Chatzopoulou, Doxa ^b   Wang, Nan ^a,b,c   Gao, Fuying ^a,b   Al Ramahi, Ismael ^d,e   Lu, Xiao Hong ^a,b,c   Ramos, Eliana Marisa ^a,b   El Zein, Karla ^d,e   Zhao, Yining ^b   Deverasetty, Sandeep ^b   Tebbe, Andreas ^f   Schaab, Christoph ^f   Lavery, Daniel J ^g   Howland, David ^g   Kwak, Seung ^g   Botas, Juan ^d,e   Aaronson, Jeffrey S ^g   Rosinski, Jim ^g   Coppola, Giovanni ^a,b,c   Horvath, Steve ^a   Yang, X William ^a,b,c   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e TEXAS CHILDREN S HOSPITAL   (United States)

^f Evotec (Munich) GmbH   (Germany)

^g CHDI MANAGEMENT CHDI FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; FIBROBLAST GROWTH FACTOR; GLUCOCORTICOID; GLUTAMATE RECEPTOR; HUNTINGTIN; MESSENGER RNA; PHOSPHOPROTEIN DARPP 32; PROTOCADHERIN; TRANSCRIPTOME; UNCLASSIFIED DRUG; HTT PROTEIN, MOUSE; NERVE PROTEIN; NUCLEAR PROTEIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAG REPEAT; CELL DEATH; CONTROLLED STUDY; CORPUS STRIATUM; DROSOPHILA; GENE EXPRESSION; GENOMICS; HUNTINGTON CHOREA; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEOMICS; RNA SEQUENCE; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; BRAIN CORTEX; C57BL MOUSE; FEMALE; GENE REGULATORY NETWORK; GENE TARGETING; GENETICS; MALE; PATHOLOGY; PHYSIOLOGY; PROCEDURES;

ANIMALS; CEREBRAL CORTEX; CORPUS STRIATUM; FEMALE; GENE KNOCK-IN TECHNIQUES; GENE REGULATORY NETWORKS; GENOMICS; HUNTINGTIN PROTEIN; MALE; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PROTEOMICS;

EID: 84959086071     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.4256     Document Type: Article

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