Blockade of astrocytic calcineurin/NFAT signaling helps to normalize hippocampal synaptic function and plasticity in a rat model of traumatic brain injury

Journal of Neuroscience

Volumn 36, Issue 5, 2016, Pages 1502-1515

  Furman, Jennifer L ^a   Sompol, Pradoldej ^b   Kraner, Susan D ^b   Pleiss, Melanie M ^a,b   Putman, Esther J ^b   Dunkerson, Jacob ^b   Abdul, Hafiz Mohmmad ^b   Roberts, Kelly N ^b   Scheff, Stephen W ^a,b   Norris, Christopher M ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Astrocytes; Brain injury; Calcineurin; Calcium; Glia; Synapse

Indexed keywords

CALCINEURIN; TRANSCRIPTION FACTOR NFAT;

ADENO ASSOCIATED VIRUS; ADULT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DEPRESSION; HIPPOCAMPUS; IMMUNOFLUORESCENCE TEST; MALE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPSE; TRAUMATIC BRAIN INJURY; UPREGULATION; WESTERN BLOTTING; ADMINISTRATION AND DOSAGE; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN INJURIES; DISEASE MODEL; GENE TRANSFER; GENE VECTOR; GENETICS; METABOLISM; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ASTROCYTES; BRAIN INJURIES; CALCINEURIN; DISEASE MODELS, ANIMAL; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HIPPOCAMPUS; MALE; NEURONAL PLASTICITY; NFATC TRANSCRIPTION FACTORS; ORGAN CULTURE TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 84957824539     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1930-15.2016     Document Type: Article

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