17β-estradiol suppresses expression of long-term depression in aged rats

Brain Research Bulletin

Volumn 53, Issue 6, 2000, Pages 783-787

  Vouimba, R M ^a,c   Foy, M R ^b   Foy, J G ^b   Thompson, R F ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b LOYOLA MARYMOUNT UNIVERSITY   (United States)

^c CNRS   (France)

Author keywords

17 estradiol; Aging; CA1; Hippocampus; LTD; Synaptic plasticity

Indexed keywords

ESTRADIOL;

AGING; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; LEARNING; MALE; MEMORY; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION; ANIMAL; ELECTROSTIMULATION; LONG TERM POTENTIATION; MEMORY DISORDER; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; POSTMENOPAUSE; SPRAGUE DAWLEY RAT;

AGING; ANIMALS; DEPRESSION; ELECTRIC STIMULATION; ESTRADIOL; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; MEMORY; MEMORY DISORDERS; NEURONAL PLASTICITY; NEURONS; POSTMENOPAUSE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034352088     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(00)00377-4     Document Type: Article

References (37)

1. Memory deficits associated with senescence; A neurophysiological and behavioral study in the rat
2. Normal aging; Regionally specific changes in hippocampal synaptic transmission
3. An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses
4. Region-specific age effects on AMPA sensitivity; Electrophysiological evidence for loss of synaptic contacts in hippocampal field CA1
5. Synaptic plasticity; LTP and LTD
6. Theory for the development of neuron selectivity; Orientation specificity and binocular interaction in visual cortex
7. A synaptic model of memory; Long-term potentiation in the hippocampus
8. Equilin, a principal component of the estrogen replacement therapy premarin, increases the growth of cortical neurons via an NMDA receptor-dependent mechanism
9. Aging changes in voltage-gated calcium currents in hippocampal CA1 neurons
10. The role of dendritic action potentials and Ca2+ influx in the induction of homosynaptic long-term depression in hippocampal CA1 pyramidal neurons
11. Estradiol enhances the induction of homosynaptic long-term depression in the CA1 region of the adult, ovariectomized rat
12. Age-related alterations in potentiation in the CA1 region in F344 rats
13. Homosynaptic long-term depression in area CA1 of the hippocampus and effects of N-methyl-D-aspartate receptor blockade
14. Involvement of hippocampal synaptic plasticity in age-related memory decline
15. Age-associated changes in Ca (2+)-dependent processes; Relation to hippocampal synaptic plasticity
16. Estrogen and neural plasticity
17. 17Beta-estradiol enhances NMDA receptor-mediated EPSPs and long-term potentiation
18. Hippocampal markers of age-related memory dysfunction; Behavioral, electrophysiological and morphological perspectives
19. Cyclical changes in endogenous levels of oestrogen modulate the induction of LTD and LTP in the hippocampal CA1 region
20. Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β-peptide toxicity in hippocampal neurons
21. Estrogen use and verbal memory in healthy postmenopausal women
22. Impaired monosynaptic potentiation in in vitro hippocampal slices from aged, memory-deficient rats
23. Impaired synaptic potentiation processes in the hippocampus of aged, memory-deficient rats
24. The effects of high Mg2+-Ca2+ ratios on frequency potentiation in hippocampal slices of young and aged rats
25. Long-term synaptic depression
26. Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus
27. Increased susceptibility to induction of long-term depression and long-term potentiation reversal during aging
28. 2+ channels
29. L-type voltage-dependent calcium channel blocker nifedipine enhances memory retention when infused into the hippocampus
30. Estrogen replacement therapy and memory in older women
31. Estrogenic effects on memory in women
32. The potential role for estrogen replacement therapy in the treatment of the cognitive decline and neurodegeneration associated with Alzheimer disease
33. Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats
34. Calcium dysregulation in neuronal aging and Alzheimer's disease; History and new directions
35. Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain
36. Long-term depression in cerebral cortex; A possible substrate of 'forgetting' that should not be forgotten