-
1
-
-
48849105507
-
The cost of cerebral ischaemia
-
COI: 1:CAS:528:DC%2BD1cXhtVSit77O, PID: 18573263
-
Flynn RW, MacWalter RS, Doney AS (2008) The cost of cerebral ischaemia. Neuropharmacology 55(3):250–256
-
(2008)
Neuropharmacology
, vol.55
, Issue.3
, pp. 250-256
-
-
Flynn, R.W.1
MacWalter, R.S.2
Doney, A.S.3
-
2
-
-
72149093510
-
Mitochondria, oxidative metabolism and cell death in stroke
-
COI: 1:CAS:528:DC%2BD1MXhsFanurbP, PID: 19751827
-
Sims NR, Muyderman H (2010) Mitochondria, oxidative metabolism and cell death in stroke. Biochim Biophys Acta 1802(1):80–91
-
(2010)
Biochim Biophys Acta
, vol.1802
, Issue.1
, pp. 80-91
-
-
Sims, N.R.1
Muyderman, H.2
-
3
-
-
43049135853
-
Stroke
-
COI: 1:CAS:528:DC%2BD1cXlslWhsbY%3D, PID: 18468545
-
Donnan GA, Fisher M, Macleod M, Davis SM (2008) Stroke. Lancet 371(9624):1612–1623
-
(2008)
Lancet
, vol.371
, Issue.9624
, pp. 1612-1623
-
-
Donnan, G.A.1
Fisher, M.2
Macleod, M.3
Davis, S.M.4
-
4
-
-
83555173511
-
Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice
-
COI: 1:CAS:528:DC%2BC3MXnsF2ltbg%3D, PID: 21681606
-
Clarke JD, Hsu A, Williams DE, Dashwood RH, Stevens JF, Yamamoto M, Ho E (2011) Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice. Pharm Res 28(12):3171–3179
-
(2011)
Pharm Res
, vol.28
, Issue.12
, pp. 3171-3179
-
-
Clarke, J.D.1
Hsu, A.2
Williams, D.E.3
Dashwood, R.H.4
Stevens, J.F.5
Yamamoto, M.6
Ho, E.7
-
5
-
-
84881526830
-
Up-down regulation of HO-1 and iNOS gene expressions by ethyl pyruvate via recruiting p300 to Nrf2 and depriving It from p65
-
COI: 1:CAS:528:DC%2BC3sXhvFyls7nI, PID: 23891677
-
Kim SW, Lee HK, Shin JH, Lee JK (2013) Up-down regulation of HO-1 and iNOS gene expressions by ethyl pyruvate via recruiting p300 to Nrf2 and depriving It from p65. Free Radic Biol Med 65:468–476
-
(2013)
Free Radic Biol Med
, vol.65
, pp. 468-476
-
-
Kim, S.W.1
Lee, H.K.2
Shin, J.H.3
Lee, J.K.4
-
6
-
-
27744438478
-
A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo
-
COI: 1:CAS:528:DC%2BD2MXht1Wqt7%2FF, PID: 16267240
-
Shih AY, Li P, Murphy TH (2005) A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo. J Neurosci 25(44):10321–10335
-
(2005)
J Neurosci
, vol.25
, Issue.44
, pp. 10321-10335
-
-
Shih, A.Y.1
Li, P.2
Murphy, T.H.3
-
7
-
-
0028061444
-
Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region
-
COI: 1:CAS:528:DyaK2MXht1Cmsbc%3D, PID: 7937919
-
Moi P, Chan K, Asunis I, Cao A, Kan YW (1994) Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proc Natl Acad Sci U S A 91(21):9926–9930
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, Issue.21
, pp. 9926-9930
-
-
Moi, P.1
Chan, K.2
Asunis, I.3
Cao, A.4
Kan, Y.W.5
-
8
-
-
84906690102
-
Effect of redox modulating NRF2 activators on chronic kidney disease
-
PID: 25140450
-
Choi BH, Kang KS, Kwak MK (2014) Effect of redox modulating NRF2 activators on chronic kidney disease. Molecules 19(8):12727–12759
-
(2014)
Molecules
, vol.19
, Issue.8
, pp. 12727-12759
-
-
Choi, B.H.1
Kang, K.S.2
Kwak, M.K.3
-
9
-
-
84910606993
-
Nrf2 augments skeletal muscle regeneration after ischaemia-reperfusion injury
-
COI: 1:CAS:528:DC%2BC2cXhvFSqu7nK, PID: 25111334
-
Al-Sawaf O, Fragoulis A, Rosen C, Keimes N, Liehn EA, Holzle F, Kan YW, Pufe T et al (2014) Nrf2 augments skeletal muscle regeneration after ischaemia-reperfusion injury. J Pathol 234(4):538–47
-
(2014)
J Pathol
, vol.234
, Issue.4
, pp. 538-547
-
-
Al-Sawaf, O.1
Fragoulis, A.2
Rosen, C.3
Keimes, N.4
Liehn, E.A.5
Holzle, F.6
Kan, Y.W.7
Pufe, T.8
-
10
-
-
84921378791
-
Association of Nrf2 polymorphism haplotypes with acute lung injury phenotypes in inbred strains of mice
-
Cho HY, Jedlicka AE, Gladwell W, Marzec J, McCaw ZR, Bienstock R, Kleeberger SR et al. (2014) Association of Nrf2 polymorphism haplotypes with acute lung injury phenotypes in inbred strains of mice. Antioxid Redox Signal
-
(2014)
Antioxid Redox Signal
-
-
Cho, H.Y.1
Jedlicka, A.E.2
Gladwell, W.3
Marzec, J.4
McCaw, Z.R.5
Bienstock, R.6
Kleeberger, S.R.7
-
11
-
-
84904667280
-
The role of Nrf2-mediated pathway in cardiac remodeling and heart failure
-
PID: 25101151
-
Zhou S, Sun W, Zhang Z, Zheng Y (2014) The role of Nrf2-mediated pathway in cardiac remodeling and heart failure. Oxid Med Cell Longev 2014:260429
-
(2014)
Oxid Med Cell Longev
, vol.2014
, pp. 260429
-
-
Zhou, S.1
Sun, W.2
Zhang, Z.3
Zheng, Y.4
-
12
-
-
84922559645
-
Role of Nrf2 in chronic liver disease
-
COI: 1:CAS:528:DC%2BC2cXhvFSksrrL, PID: 25278702
-
Tang W, Jiang YF, Ponnusamy M, Diallo M (2014) Role of Nrf2 in chronic liver disease. World J Gastroenterol 20(36):13079–13087
-
(2014)
World J Gastroenterol
, vol.20
, Issue.36
, pp. 13079-13087
-
-
Tang, W.1
Jiang, Y.F.2
Ponnusamy, M.3
Diallo, M.4
-
13
-
-
85012836517
-
An overview of the molecular mechanisms and novel roles of Nrf2 in neurodegenerative disorders
-
Yang Y, Jiang S, Yan J, Li Y, Xin Z, Lin Y, Qu Y (2014) An overview of the molecular mechanisms and novel roles of Nrf2 in neurodegenerative disorders. Cytokine Growth Factor Rev
-
(2014)
Cytokine Growth Factor Rev
-
-
Yang, Y.1
Jiang, S.2
Yan, J.3
Li, Y.4
Xin, Z.5
Lin, Y.6
Qu, Y.7
-
14
-
-
84867777145
-
The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases
-
COI: 1:CAS:528:DC%2BC38Xhs12hu7%2FJ, PID: 22742419
-
Joshi G, Johnson JA (2012) The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases. Recent Pat CNS Drug Discov 7(3):218–229
-
(2012)
Recent Pat CNS Drug Discov
, vol.7
, Issue.3
, pp. 218-229
-
-
Joshi, G.1
Johnson, J.A.2
-
15
-
-
84870902532
-
Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection
-
COI: 1:CAS:528:DC%2BC38XhvVCktb%2FK, PID: 23025925
-
Zhang M, An C, Gao Y, Leak RK, Chen J, Zhang F (2013) Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection. Prog Neurobiol 100:30–47
-
(2013)
Prog Neurobiol
, vol.100
, pp. 30-47
-
-
Zhang, M.1
An, C.2
Gao, Y.3
Leak, R.K.4
Chen, J.5
Zhang, F.6
-
16
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
COI: 1:CAS:528:DyaK2sXkvVWns78%3D, PID: 9240432
-
Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, Oyake T, Hayashi N et al (1997) An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 236(2):313–322
-
(1997)
Biochem Biophys Res Commun
, vol.236
, Issue.2
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
-
17
-
-
24344479164
-
Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes
-
COI: 1:CAS:528:DC%2BD2MXhtVWisLzJ, PID: 16135796
-
Katsuoka F, Motohashi H, Ishii T, Aburatani H, Engel JD, Yamamoto M (2005) Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes. Mol Cell Biol 25(18):8044–8051
-
(2005)
Mol Cell Biol
, vol.25
, Issue.18
, pp. 8044-8051
-
-
Katsuoka, F.1
Motohashi, H.2
Ishii, T.3
Aburatani, H.4
Engel, J.D.5
Yamamoto, M.6
-
18
-
-
7244253081
-
Nrf2-Keap1 defines a physiologically important stress response mechanism
-
COI: 1:CAS:528:DC%2BD2cXptFKktbk%3D, PID: 15519281
-
Motohashi H, Yamamoto M (2004) Nrf2-Keap1 defines a physiologically important stress response mechanism. Trends Mol Med 10(11):549–557
-
(2004)
Trends Mol Med
, vol.10
, Issue.11
, pp. 549-557
-
-
Motohashi, H.1
Yamamoto, M.2
-
19
-
-
28544450507
-
The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation
-
COI: 1:CAS:528:DC%2BD2MXhtlektr%2FP, PID: 16314513
-
Nioi P, Nguyen T, Sherratt PJ, Pickett CB (2005) The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation. Mol Cell Biol 25(24):10895–10906
-
(2005)
Mol Cell Biol
, vol.25
, Issue.24
, pp. 10895-10906
-
-
Nioi, P.1
Nguyen, T.2
Sherratt, P.J.3
Pickett, C.B.4
-
20
-
-
0034752461
-
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
-
COI: 1:CAS:528:DC%2BD3MXotlCmtbc%3D, PID: 11683914
-
Katoh Y, Itoh K, Yoshida E, Miyagishi M, Fukamizu A, Yamamoto M (2001) Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells 6(10):857–868
-
(2001)
Genes Cells
, vol.6
, Issue.10
, pp. 857-868
-
-
Katoh, Y.1
Itoh, K.2
Yoshida, E.3
Miyagishi, M.4
Fukamizu, A.5
Yamamoto, M.6
-
21
-
-
3843104763
-
Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron
-
COI: 1:CAS:528:DC%2BD2cXlslOrsbg%3D, PID: 15143058
-
McMahon M, Thomas N, Itoh K, Yamamoto M, Hayes JD (2004) Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron. J Biol Chem 279(30):31556–31567
-
(2004)
J Biol Chem
, vol.279
, Issue.30
, pp. 31556-31567
-
-
McMahon, M.1
Thomas, N.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
22
-
-
0242580049
-
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
COI: 1:CAS:528:DC%2BD3sXovVKjtr4%3D, PID: 14585973
-
Zhang DD, Hannink M (2003) Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol Cell Biol 23(22):8137–8151
-
(2003)
Mol Cell Biol
, vol.23
, Issue.22
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
23
-
-
42149196050
-
Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity
-
COI: 1:CAS:528:DC%2BD1cXksFWqt7w%3D, PID: 18268004
-
Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, Yamamoto M (2008) Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity. Mol Cell Biol 28(8):2758–2770
-
(2008)
Mol Cell Biol
, vol.28
, Issue.8
, pp. 2758-2770
-
-
Yamamoto, T.1
Suzuki, T.2
Kobayashi, A.3
Wakabayashi, J.4
Maher, J.5
Motohashi, H.6
Yamamoto, M.7
-
24
-
-
10044228504
-
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
-
COI: 1:CAS:528:DC%2BD2cXhtFSgsr%2FL, PID: 15572695
-
Zhang DD, Lo SC, Cross JV, Templeton DJ, Hannink M (2004) Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol Cell Biol 24(24):10941–10953
-
(2004)
Mol Cell Biol
, vol.24
, Issue.24
, pp. 10941-10953
-
-
Zhang, D.D.1
Lo, S.C.2
Cross, J.V.3
Templeton, D.J.4
Hannink, M.5
-
25
-
-
46749152185
-
Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction
-
COI: 1:CAS:528:DC%2BD1cXosVOjsLo%3D, PID: 18417180
-
Wang XJ, Sun Z, Chen W, Li Y, Villeneuve NF, Zhang DD (2008) Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction. Toxicol Appl Pharmacol 230(3):383–389
-
(2008)
Toxicol Appl Pharmacol
, vol.230
, Issue.3
, pp. 383-389
-
-
Wang, X.J.1
Sun, Z.2
Chen, W.3
Li, Y.4
Villeneuve, N.F.5
Zhang, D.D.6
-
26
-
-
78650509515
-
Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals
-
COI: 1:CAS:528:DC%2BC3cXhsVCqsbzM, PID: 20956331
-
McMahon M, Lamont DJ, Beattie KA, Hayes JD (2010) Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals. Proc Natl Acad Sci U S A 107(44):18838–18843
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.44
, pp. 18838-18843
-
-
McMahon, M.1
Lamont, D.J.2
Beattie, K.A.3
Hayes, J.D.4
-
27
-
-
35648970026
-
Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response
-
COI: 1:CAS:528:DC%2BD2sXht1GltrvE, PID: 17785452
-
Tong KI, Padmanabhan B, Kobayashi A, Shang C, Hirotsu Y, Yokoyama S, Yamamoto M (2007) Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response. Mol Cell Biol 27(21):7511–7521
-
(2007)
Mol Cell Biol
, vol.27
, Issue.21
, pp. 7511-7521
-
-
Tong, K.I.1
Padmanabhan, B.2
Kobayashi, A.3
Shang, C.4
Hirotsu, Y.5
Yokoyama, S.6
Yamamoto, M.7
-
28
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
-
COI: 1:CAS:528:DC%2BD2cXmtlOjt7w%3D, PID: 15282312
-
Kobayashi A, Kang MI, Okawa H, Ohtsuji M, Zenke Y, Chiba T, Igarashi K, Yamamoto M (2004) Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol Cell Biol 24(16):7130–7139
-
(2004)
Mol Cell Biol
, vol.24
, Issue.16
, pp. 7130-7139
-
-
Kobayashi, A.1
Kang, M.I.2
Okawa, H.3
Ohtsuji, M.4
Zenke, Y.5
Chiba, T.6
Igarashi, K.7
Yamamoto, M.8
-
29
-
-
1642282736
-
Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products
-
COI: 1:CAS:528:DC%2BD2cXisVajsLk%3D, PID: 14616092
-
Levonen AL, Landar A, Ramachandran A, Ceaser EK, Dickinson DA, Zanoni G, Morrow JD, Darley-Usmar VM (2004) Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products. Biochem J 378(Pt 2):373–382
-
(2004)
Biochem J
, vol.378
, pp. 373-382
-
-
Levonen, A.L.1
Landar, A.2
Ramachandran, A.3
Ceaser, E.K.4
Dickinson, D.A.5
Zanoni, G.6
Morrow, J.D.7
Darley-Usmar, V.M.8
-
30
-
-
44049093741
-
Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2
-
COI: 1:CAS:528:DC%2BD1cXjslyrtb0%3D, PID: 18238777
-
Theodore M, Kawai Y, Yang J, Kleshchenko Y, Reddy SP, Villalta F, Arinze IJ (2008) Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2. J Biol Chem 283(14):8984–8994
-
(2008)
J Biol Chem
, vol.283
, Issue.14
, pp. 8984-8994
-
-
Theodore, M.1
Kawai, Y.2
Yang, J.3
Kleshchenko, Y.4
Reddy, S.P.5
Villalta, F.6
Arinze, I.J.7
-
31
-
-
0242666198
-
Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression
-
COI: 1:CAS:528:DC%2BD3sXoslWls7s%3D, PID: 12947090
-
Bloom DA, Jaiswal AK (2003) Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression. J Biol Chem 278(45):44675–44682
-
(2003)
J Biol Chem
, vol.278
, Issue.45
, pp. 44675-44682
-
-
Bloom, D.A.1
Jaiswal, A.K.2
-
32
-
-
0242721624
-
Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway
-
COI: 1:CAS:528:DC%2BD3sXptFaitrs%3D, PID: 14612418
-
Kwak MK, Wakabayashi N, Greenlaw JL, Yamamoto M, Kensler TW (2003) Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway. Mol Cell Biol 23(23):8786–8794
-
(2003)
Mol Cell Biol
, vol.23
, Issue.23
, pp. 8786-8794
-
-
Kwak, M.K.1
Wakabayashi, N.2
Greenlaw, J.L.3
Yamamoto, M.4
Kensler, T.W.5
-
33
-
-
77954374004
-
An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance
-
COI: 1:CAS:528:DC%2BC3cXos1Wrsbk%3D, PID: 20452971
-
Kaspar JW, Jaiswal AK (2010) An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance. J Biol Chem 285(28):21349–21358
-
(2010)
J Biol Chem
, vol.285
, Issue.28
, pp. 21349-21358
-
-
Kaspar, J.W.1
Jaiswal, A.K.2
-
34
-
-
84866283856
-
Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/beta-TrCP axis
-
COI: 1:CAS:528:DC%2BC38Xht1OlurzF, PID: 22751928
-
Rada P, Rojo AI, Evrard-Todeschi N, Innamorato NG, Cotte A, Jaworski T, Tobon-Velasco JC, Devijver H et al (2012) Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/beta-TrCP axis. Mol Cell Biol 32(17):3486–3499
-
(2012)
Mol Cell Biol
, vol.32
, Issue.17
, pp. 3486-3499
-
-
Rada, P.1
Rojo, A.I.2
Evrard-Todeschi, N.3
Innamorato, N.G.4
Cotte, A.5
Jaworski, T.6
Tobon-Velasco, J.C.7
Devijver, H.8
-
35
-
-
34447526197
-
GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2
-
COI: 1:CAS:528:DC%2BD2sXlvVajtb8%3D, PID: 17403689
-
Jain AK, Jaiswal AK (2007) GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2. J Biol Chem 282(22):16502–16510
-
(2007)
J Biol Chem
, vol.282
, Issue.22
, pp. 16502-16510
-
-
Jain, A.K.1
Jaiswal, A.K.2
-
36
-
-
67649415378
-
Prothymosin-alpha mediates nuclear import of the INrf2/Cul3 Rbx1 complex to degrade nuclear Nrf2
-
COI: 1:CAS:528:DC%2BD1MXls1KisbY%3D, PID: 19279002
-
Niture SK, Jaiswal AK (2009) Prothymosin-alpha mediates nuclear import of the INrf2/Cul3 Rbx1 complex to degrade nuclear Nrf2. J Biol Chem 284(20):13856–13868
-
(2009)
J Biol Chem
, vol.284
, Issue.20
, pp. 13856-13868
-
-
Niture, S.K.1
Jaiswal, A.K.2
-
37
-
-
84901262927
-
Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases
-
Gan L, Johnson JA (2013) Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases. Biochim Biophys Acta
-
(2013)
Biochim Biophys Acta
-
-
Gan, L.1
Johnson, J.A.2
-
38
-
-
71549144988
-
Lipid oxidation and peroxidation in CNS health and disease: from molecular mechanisms to therapeutic opportunities
-
COI: 1:CAS:528:DC%2BC3cXhsFejt7k%3D, PID: 19624272
-
Adibhatla RM, Hatcher JF (2010) Lipid oxidation and peroxidation in CNS health and disease: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal 12(1):125–169
-
(2010)
Antioxid Redox Signal
, vol.12
, Issue.1
, pp. 125-169
-
-
Adibhatla, R.M.1
Hatcher, J.F.2
-
39
-
-
0024785709
-
Oxygen radicals in CNS damage
-
COI: 1:CAS:528:DyaK3cXntFOhsg%3D%3D, PID: 2557981
-
Kontos HA (1989) Oxygen radicals in CNS damage. Chem Biol Interact 72(3):229–255
-
(1989)
Chem Biol Interact
, vol.72
, Issue.3
, pp. 229-255
-
-
Kontos, H.A.1
-
40
-
-
0017852672
-
Free radicals in cerebral ischemia
-
COI: 1:CAS:528:DyaE1cXlslOnu7Y%3D, PID: 705824
-
Flamm ES, Demopoulos HB, Seligman ML, Poser RG, Ransohoff J (1978) Free radicals in cerebral ischemia. Stroke 9(5):445–447
-
(1978)
Stroke
, vol.9
, Issue.5
, pp. 445-447
-
-
Flamm, E.S.1
Demopoulos, H.B.2
Seligman, M.L.3
Poser, R.G.4
Ransohoff, J.5
-
41
-
-
79958255054
-
Molecular pathophysiology of cerebral hemorrhage: secondary brain injury
-
PID: 21527759
-
Aronowski J, Zhao X (2011) Molecular pathophysiology of cerebral hemorrhage: secondary brain injury. Stroke 42(6):1781–1786
-
(2011)
Stroke
, vol.42
, Issue.6
, pp. 1781-1786
-
-
Aronowski, J.1
Zhao, X.2
-
42
-
-
5644241361
-
Brain ischemic preconditioning is abolished by antioxidant drugs but does not up-regulate superoxide dismutase and glutathion peroxidase
-
COI: 1:CAS:528:DC%2BD2cXos1egsrc%3D, PID: 15494154
-
Puisieux F, Deplanque D, Bulckaen H, Maboudou P, Gele P, Lhermitte M, Lebuffe G, Bordet R (2004) Brain ischemic preconditioning is abolished by antioxidant drugs but does not up-regulate superoxide dismutase and glutathion peroxidase. Brain Res 1027(1–2):30–37
-
(2004)
Brain Res
, vol.1027
, Issue.1-2
, pp. 30-37
-
-
Puisieux, F.1
Deplanque, D.2
Bulckaen, H.3
Maboudou, P.4
Gele, P.5
Lhermitte, M.6
Lebuffe, G.7
Bordet, R.8
-
43
-
-
36348935147
-
epsilonPKC phosphorylates the mitochondrial K(+) (ATP) channel during induction of ischemic preconditioning in the rat hippocampus
-
COI: 1:CAS:528:DC%2BD2sXhtlyrs7nF, PID: 17988655
-
Raval AP, Dave KR, DeFazio RA, Perez-Pinzon MA (2007) epsilonPKC phosphorylates the mitochondrial K(+) (ATP) channel during induction of ischemic preconditioning in the rat hippocampus. Brain Res 1184:345–353
-
(2007)
Brain Res
, vol.1184
, pp. 345-353
-
-
Raval, A.P.1
Dave, K.R.2
DeFazio, R.A.3
Perez-Pinzon, M.A.4
-
44
-
-
84874864664
-
Redox signaling pathways involved in neuronal ischemic preconditioning
-
COI: 1:CAS:528:DC%2BC3sXlt1Olsw%3D%3D, PID: 23730259
-
Thompson JW, Narayanan SV, Perez-Pinzon MA (2012) Redox signaling pathways involved in neuronal ischemic preconditioning. Curr Neuropharmacol 10(4):354–369
-
(2012)
Curr Neuropharmacol
, vol.10
, Issue.4
, pp. 354-369
-
-
Thompson, J.W.1
Narayanan, S.V.2
Perez-Pinzon, M.A.3
-
45
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
-
COI: 1:CAS:528:DC%2BD3MXit1altb8%3D, PID: 11248092
-
Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW (2001) Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci U S A 98(6):3410–3415
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.6
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
Kwak, M.K.2
Dolan, P.M.3
Itoh, K.4
Yamamoto, M.5
Talalay, P.6
Kensler, T.W.7
-
46
-
-
84872667758
-
Nrf2 to pre-condition the brain against injury caused by products of hemolysis after ICH
-
COI: 1:CAS:528:DC%2BC3sXhtlGnur4%3D, PID: 23378859
-
Zhao X, Aronowski J (2013) Nrf2 to pre-condition the brain against injury caused by products of hemolysis after ICH. Transl Stroke Res 4(1):71–75
-
(2013)
Transl Stroke Res
, vol.4
, Issue.1
, pp. 71-75
-
-
Zhao, X.1
Aronowski, J.2
-
47
-
-
84859711023
-
The importance of early brain injury after subarachnoid hemorrhage
-
PID: 22414893
-
Sehba FA, Hou J, Pluta RM, Zhang JH (2012) The importance of early brain injury after subarachnoid hemorrhage. Prog Neurobiol 97(1):14–37
-
(2012)
Prog Neurobiol
, vol.97
, Issue.1
, pp. 14-37
-
-
Sehba, F.A.1
Hou, J.2
Pluta, R.M.3
Zhang, J.H.4
-
48
-
-
84897411733
-
Genetic elimination of Nrf2 aggravates secondary complications except for vasospasm after experimental subarachnoid hemorrhage in mice
-
COI: 1:CAS:528:DC%2BC2cXkt1ags7o%3D, PID: 24576487
-
Li T, Wang H, Ding Y, Zhou M, Zhou X, Zhang X, Ding K, He J et al (2014) Genetic elimination of Nrf2 aggravates secondary complications except for vasospasm after experimental subarachnoid hemorrhage in mice. Brain Res 1558:90–99
-
(2014)
Brain Res
, vol.1558
, pp. 90-99
-
-
Li, T.1
Wang, H.2
Ding, Y.3
Zhou, M.4
Zhou, X.5
Zhang, X.6
Ding, K.7
He, J.8
-
49
-
-
0037307212
-
To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways
-
COI: 1:CAS:528:DC%2BD3sXis1yqt74%3D, PID: 12684068
-
Liou AK, Clark RS, Henshall DC, Yin XM, Chen J (2003) To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways. Prog Neurobiol 69(2):103–142
-
(2003)
Prog Neurobiol
, vol.69
, Issue.2
, pp. 103-142
-
-
Liou, A.K.1
Clark, R.S.2
Henshall, D.C.3
Yin, X.M.4
Chen, J.5
-
50
-
-
84906056961
-
Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage
-
COI: 1:CAS:528:DC%2BC2cXhtlymsL%2FE, PID: 24796605
-
Jacobsen A, Nielsen TH, Nilsson O, Schalen W, Nordstrom CH (2014) Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage. Acta Neurol Scand 130(3):156–163
-
(2014)
Acta Neurol Scand
, vol.130
, Issue.3
, pp. 156-163
-
-
Jacobsen, A.1
Nielsen, T.H.2
Nilsson, O.3
Schalen, W.4
Nordstrom, C.H.5
-
51
-
-
84878224232
-
Mitochondrial diseases of the brain
-
COI: 1:CAS:528:DC%2BC3sXhtFyjt7rE, PID: 23567191
-
Chaturvedi RK, Flint Beal M (2013) Mitochondrial diseases of the brain. Free Radic Biol Med 63:1–29
-
(2013)
Free Radic Biol Med
, vol.63
, pp. 1-29
-
-
Chaturvedi, R.K.1
Flint Beal, M.2
-
52
-
-
0022321324
-
The effects of medroxyprogesterone acetate on enzyme activities in human endometrial carcinoma
-
COI: 1:CAS:528:DyaL28XhsVant7k%3D, PID: 2936931
-
Philipson KA, Elder MG, White JO (1985) The effects of medroxyprogesterone acetate on enzyme activities in human endometrial carcinoma. J Steroid Biochem 23(6A):1059–1064
-
(1985)
J Steroid Biochem
, vol.23
, Issue.6A
, pp. 1059-1064
-
-
Philipson, K.A.1
Elder, M.G.2
White, J.O.3
-
53
-
-
84892752587
-
Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons
-
COI: 1:CAS:528:DC%2BC3sXhslGmt7vM, PID: 24219236
-
Leiros M, Alonso E, Sanchez JA, Rateb ME, Ebel R, Houssen WE, Jaspars M, Alfonso A et al (2014) Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons. ACS Chem Neurosci 5(1):71–80
-
(2014)
ACS Chem Neurosci
, vol.5
, Issue.1
, pp. 71-80
-
-
Leiros, M.1
Alonso, E.2
Sanchez, J.A.3
Rateb, M.E.4
Ebel, R.5
Houssen, W.E.6
Jaspars, M.7
Alfonso, A.8
-
54
-
-
84942197145
-
-
Zhang C, Zhang Z, Zhao Q, Wang X, Ji H, Zhang Y (2013)(S)-ZJM-289 Preconditioning Induces a Late Phase Protection Against Nervous Injury Induced by Transient Cerebral Ischemia and Oxygen-Glucose Deprivation
-
Zhang C, Zhang Z, Zhao Q, Wang X, Ji H, Zhang Y (2013) (S)-ZJM-289 Preconditioning Induces a Late Phase Protection Against Nervous Injury Induced by Transient Cerebral Ischemia and Oxygen-Glucose Deprivation. Neurotox Res
-
(2013)
Neurotox Res
-
-
-
55
-
-
84902135938
-
Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia-reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways
-
Meng X, Wang M, Wang X, Sun G, Ye J, Xu H, Sun X (2014) Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia-reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways. Free Radic Res
-
(2014)
Free Radic Res
-
-
Meng, X.1
Wang, M.2
Wang, X.3
Sun, G.4
Ye, J.5
Xu, H.6
Sun, X.7
-
56
-
-
26444442450
-
Endoplasmic reticulum stress: cell life and death decisions
-
COI: 1:CAS:528:DC%2BD2MXhtVygt7jO, PID: 16200199
-
Xu C, Bailly-Maitre B, Reed JC (2005) Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 115(10):2656–2664
-
(2005)
J Clin Invest
, vol.115
, Issue.10
, pp. 2656-2664
-
-
Xu, C.1
Bailly-Maitre, B.2
Reed, J.C.3
-
57
-
-
68149136657
-
Cellular responses to endoplasmic reticulum stress and apoptosis
-
PID: 19360473
-
Rasheva VI, Domingos PM (2009) Cellular responses to endoplasmic reticulum stress and apoptosis. Apoptosis 14(8):996–1007
-
(2009)
Apoptosis
, vol.14
, Issue.8
, pp. 996-1007
-
-
Rasheva, V.I.1
Domingos, P.M.2
-
58
-
-
77957875161
-
Activation of PERK signaling through fluoride-mediated endoplasmic reticulum stress in OS732 cells
-
COI: 1:CAS:528:DC%2BC3cXhtlShur%2FN, PID: 20709135
-
Xu H, Zhou YL, Zhang XY, Lu P, Li GS (2010) Activation of PERK signaling through fluoride-mediated endoplasmic reticulum stress in OS732 cells. Toxicology 277(1–3):1–5
-
(2010)
Toxicology
, vol.277
, Issue.1-3
, pp. 1-5
-
-
Xu, H.1
Zhou, Y.L.2
Zhang, X.Y.3
Lu, P.4
Li, G.S.5
-
59
-
-
84939889520
-
Endoplasmic Reticulum Stress: Relevance and Therapeutics in Central Nervous System Diseases
-
Zhang HY, Wang ZG, Lu XH, Kong XX, Wu FZ, Lin L, Tan X, Ye LB et al. (2014) Endoplasmic Reticulum Stress: Relevance and Therapeutics in Central Nervous System Diseases. Mol Neurobiol 51(3):1343–1352
-
(2014)
Mol Neurobiol
, vol.51
, Issue.3
, pp. 1343-1352
-
-
Zhang, H.Y.1
Wang, Z.G.2
Lu, X.H.3
Kong, X.X.4
Wu, F.Z.5
Lin, L.6
Tan, X.7
Ye, L.B.8
-
60
-
-
27944504351
-
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
PID: 16286508
-
Bjorkoy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T (2005) p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol 171(4):603–614
-
(2005)
J Cell Biol
, vol.171
, Issue.4
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
Overvatn, A.6
Stenmark, H.7
Johansen, T.8
-
61
-
-
77953366801
-
A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62
-
COI: 1:CAS:528:DC%2BC3cXptVegu7k%3D, PID: 20421418
-
Lau A, Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E et al (2010) A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. Mol Cell Biol 30(13):3275–3285
-
(2010)
Mol Cell Biol
, vol.30
, Issue.13
, pp. 3275-3285
-
-
Lau, A.1
Wang, X.J.2
Zhao, F.3
Villeneuve, N.F.4
Wu, T.5
Jiang, T.6
Sun, Z.7
White, E.8
-
62
-
-
77954599053
-
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
-
COI: 1:CAS:528:DC%2BC3cXos1WntLg%3D, PID: 20452972
-
Jain A, Lamark T, Sjottem E, Larsen KB, Awuh JA, Overvatn A, McMahon M, Hayes JD et al (2010) p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. J Biol Chem 285(29):22576–22591
-
(2010)
J Biol Chem
, vol.285
, Issue.29
, pp. 22576-22591
-
-
Jain, A.1
Lamark, T.2
Sjottem, E.3
Larsen, K.B.4
Awuh, J.A.5
Overvatn, A.6
McMahon, M.7
Hayes, J.D.8
-
63
-
-
84879402330
-
Regulation of endoplasmic reticulum stress in rat cortex by p62/ZIP through the Keap1-Nrf2-ARE signalling pathway after transient focal cerebral ischaemia
-
PID: 23782269
-
Wang W, Kang J, Li H, Su J, Wu J, Xu Y, Yu H, Xiang X et al (2013) Regulation of endoplasmic reticulum stress in rat cortex by p62/ZIP through the Keap1-Nrf2-ARE signalling pathway after transient focal cerebral ischaemia. Brain Inj 27(7–8):924–933
-
(2013)
Brain Inj
, vol.27
, Issue.7-8
, pp. 924-933
-
-
Wang, W.1
Kang, J.2
Li, H.3
Su, J.4
Wu, J.5
Xu, Y.6
Yu, H.7
Xiang, X.8
-
64
-
-
84896873325
-
Endoplasmic reticulum stress is associated with neuroprotection against apoptosis via autophagy activation in a rat model of subarachnoid hemorrhage
-
COI: 1:CAS:528:DC%2BC2cXjvFWit7s%3D, PID: 24513235
-
Yan F, Li J, Chen J, Hu Q, Gu C, Lin W, Chen G (2014) Endoplasmic reticulum stress is associated with neuroprotection against apoptosis via autophagy activation in a rat model of subarachnoid hemorrhage. Neurosci Lett 563:160–165
-
(2014)
Neurosci Lett
, vol.563
, pp. 160-165
-
-
Yan, F.1
Li, J.2
Chen, J.3
Hu, Q.4
Gu, C.5
Lin, W.6
Chen, G.7
-
65
-
-
84898843177
-
Microglia-mediated neuroinflammation is an amplifier of virus-induced neuropathology
-
COI: 1:CAS:528:DC%2BC2cXls12msb8%3D, PID: 23979705
-
Das Sarma J (2014) Microglia-mediated neuroinflammation is an amplifier of virus-induced neuropathology. J Neurovirol 20(2):122–136
-
(2014)
J Neurovirol
, vol.20
, Issue.2
, pp. 122-136
-
-
Das Sarma, J.1
-
66
-
-
84856218681
-
Artesunate activates Nrf2 pathway-driven anti-inflammatory potential through ERK signaling in microglial BV2 cells
-
COI: 1:CAS:528:DC%2BC38XhsFGrtLw%3D, PID: 22227297
-
Lee IS, Ryu DK, Lim J, Cho S, Kang BY, Choi HJ (2012) Artesunate activates Nrf2 pathway-driven anti-inflammatory potential through ERK signaling in microglial BV2 cells. Neurosci Lett 509(1):17–21
-
(2012)
Neurosci Lett
, vol.509
, Issue.1
, pp. 17-21
-
-
Lee, I.S.1
Ryu, D.K.2
Lim, J.3
Cho, S.4
Kang, B.Y.5
Choi, H.J.6
-
67
-
-
84886237017
-
Sulforaphane ameliorates the development of experimental autoimmune encephalomyelitis by antagonizing oxidative stress and Th17-related inflammation in mice
-
COI: 1:CAS:528:DC%2BC3sXhvFWit7zI, PID: 24120440
-
Li B, Cui W, Liu J, Li R, Liu Q, Xie XH, Ge XL, Zhang J et al (2013) Sulforaphane ameliorates the development of experimental autoimmune encephalomyelitis by antagonizing oxidative stress and Th17-related inflammation in mice. Exp Neurol 250:239–249
-
(2013)
Exp Neurol
, vol.250
, pp. 239-249
-
-
Li, B.1
Cui, W.2
Liu, J.3
Li, R.4
Liu, Q.5
Xie, X.H.6
Ge, X.L.7
Zhang, J.8
-
68
-
-
84870893039
-
Postischemic brain infiltration of leukocyte subpopulations differs among murine permanent and transient focal cerebral ischemia models
-
COI: 1:CAS:528:DC%2BC3sXisVKmtLg%3D, PID: 22775530
-
Zhou W, Liesz A, Bauer H, Sommer C, Lahrmann B, Valous N, Grabe N, Veltkamp R (2013) Postischemic brain infiltration of leukocyte subpopulations differs among murine permanent and transient focal cerebral ischemia models. Brain Pathol 23(1):34–44
-
(2013)
Brain Pathol
, vol.23
, Issue.1
, pp. 34-44
-
-
Zhou, W.1
Liesz, A.2
Bauer, H.3
Sommer, C.4
Lahrmann, B.5
Valous, N.6
Grabe, N.7
Veltkamp, R.8
-
69
-
-
84887610342
-
Docosahexaenoic acid reduces cellular inflammatory response following permanent focal cerebral ischemia in rats
-
COI: 1:CAS:528:DC%2BC3sXhs1Cltr7K, PID: 24139673
-
Chang CY, Kuan YH, Li JR, Chen WY, Ou YC, Pan HC, Liao SL, Raung SL et al (2013) Docosahexaenoic acid reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. J Nutr Biochem 24(12):2127–2137
-
(2013)
J Nutr Biochem
, vol.24
, Issue.12
, pp. 2127-2137
-
-
Chang, C.Y.1
Kuan, Y.H.2
Li, J.R.3
Chen, W.Y.4
Ou, Y.C.5
Pan, H.C.6
Liao, S.L.7
Raung, S.L.8
-
70
-
-
79957515007
-
Pharmacological targeting of the transcription factor Nrf2 at the basal ganglia provides disease modifying therapy for experimental parkinsonism
-
COI: 1:CAS:528:DC%2BC3MXmtl2ksr4%3D, PID: 21254817
-
Jazwa A, Rojo AI, Innamorato NG, Hesse M, Fernandez-Ruiz J, Cuadrado A (2011) Pharmacological targeting of the transcription factor Nrf2 at the basal ganglia provides disease modifying therapy for experimental parkinsonism. Antioxid Redox Signal 14(12):2347–2360
-
(2011)
Antioxid Redox Signal
, vol.14
, Issue.12
, pp. 2347-2360
-
-
Jazwa, A.1
Rojo, A.I.2
Innamorato, N.G.3
Hesse, M.4
Fernandez-Ruiz, J.5
Cuadrado, A.6
-
71
-
-
84884493497
-
Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood–brain barrier disruption and neurological deficits in stroke
-
COI: 1:CAS:528:DC%2BC3sXhvFylurjM, PID: 24017972
-
Alfieri A, Srivastava S, Siow RC, Cash D, Modo M, Duchen MR, Fraser PA, Williams SC et al (2013) Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood–brain barrier disruption and neurological deficits in stroke. Free Radic Biol Med 65:1012–1022
-
(2013)
Free Radic Biol Med
, vol.65
, pp. 1012-1022
-
-
Alfieri, A.1
Srivastava, S.2
Siow, R.C.3
Cash, D.4
Modo, M.5
Duchen, M.R.6
Fraser, P.A.7
Williams, S.C.8
-
72
-
-
77951526269
-
Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose deprivation
-
COI: 1:CAS:528:DC%2BC3cXisFakurc%3D, PID: 19998483
-
Soane L, Li Dai W, Fiskum G, Bambrick LL (2010) Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose deprivation. J Neurosci Res 88(6):1355–1363
-
(2010)
J Neurosci Res
, vol.88
, Issue.6
, pp. 1355-1363
-
-
Soane, L.1
Li Dai, W.2
Fiskum, G.3
Bambrick, L.L.4
-
73
-
-
78650814146
-
Repeated transient sulforaphane stimulation in astrocytes leads to prolonged Nrf2-mediated gene expression and protection from superoxide-induced damage
-
PID: 20888844
-
Bergstrom P, Andersson HC, Gao Y, Karlsson JO, Nodin C, Anderson MF, Nilsson M, Hammarsten O (2011) Repeated transient sulforaphane stimulation in astrocytes leads to prolonged Nrf2-mediated gene expression and protection from superoxide-induced damage. Neuropharmacology 60(2–3):343–353
-
(2011)
Neuropharmacology
, vol.60
, Issue.2-3
, pp. 343-353
-
-
Bergstrom, P.1
Andersson, H.C.2
Gao, Y.3
Karlsson, J.O.4
Nodin, C.5
Anderson, M.F.6
Nilsson, M.7
Hammarsten, O.8
-
74
-
-
84864275231
-
Photothrombosis-induced infarction of the mouse cerebral cortex is not affected by the Nrf2-activator sulforaphane
-
COI: 1:CAS:528:DC%2BC38XhtFWis7rF, PID: 22911746
-
Porritt MJ, Andersson HC, Hou L, Nilsson A, Pekna M, Pekny M, Nilsson M (2012) Photothrombosis-induced infarction of the mouse cerebral cortex is not affected by the Nrf2-activator sulforaphane. PLoS One 7(7), e41090
-
(2012)
PLoS One
, vol.7
, Issue.7
-
-
Porritt, M.J.1
Andersson, H.C.2
Hou, L.3
Nilsson, A.4
Pekna, M.5
Pekny, M.6
Nilsson, M.7
-
75
-
-
79751525643
-
Role of the Nrf2-ARE pathway in early brain injury after experimental subarachnoid hemorrhage
-
COI: 1:CAS:528:DC%2BC3MXhslOjsLY%3D, PID: 21259333
-
Chen G, Fang Q, Zhang J, Zhou D, Wang Z (2011) Role of the Nrf2-ARE pathway in early brain injury after experimental subarachnoid hemorrhage. J Neurosci Res 89(4):515–523
-
(2011)
J Neurosci Res
, vol.89
, Issue.4
, pp. 515-523
-
-
Chen, G.1
Fang, Q.2
Zhang, J.3
Zhou, D.4
Wang, Z.5
-
76
-
-
84882592906
-
Sulforaphane enhances the activity of the Nrf2-ARE pathway and attenuates inflammation in OxyHb-induced rat vascular smooth muscle cells
-
COI: 1:CAS:528:DC%2BC3sXht1OiurfI, PID: 23756573
-
Zhao XD, Zhou YT, Lu XJ (2013) Sulforaphane enhances the activity of the Nrf2-ARE pathway and attenuates inflammation in OxyHb-induced rat vascular smooth muscle cells. Inflamm Res 62(9):857–863
-
(2013)
Inflamm Res
, vol.62
, Issue.9
, pp. 857-863
-
-
Zhao, X.D.1
Zhou, Y.T.2
Lu, X.J.3
-
77
-
-
84906219165
-
-
Sulforaphane induces autophagy through ERK activation in neuronal cells, FEBS Lett
-
Jo C, Kim S, Cho SJ, Choi KJ, Yun SM, Koh YH, Johnson GV, Park SI et al. (2014) Sulforaphane induces autophagy through ERK activation in neuronal cells. FEBS Lett
-
(2014)
Park SI et al
-
-
Jo, C.1
Kim, S.2
Cho, S.J.3
Choi, K.J.4
Yun, S.M.5
Koh, Y.H.6
Johnson, G.V.7
-
78
-
-
84861469141
-
Ethyl pyruvate-mediated Nrf2 activation and hemeoxygenase 1 induction in astrocytes confer protective effects via autocrine and paracrine mechanisms
-
COI: 1:CAS:528:DC%2BC38XptFCmtbg%3D, PID: 22521774
-
Shin JH, Kim SW, Jin Y, Kim ID, Lee JK (2012) Ethyl pyruvate-mediated Nrf2 activation and hemeoxygenase 1 induction in astrocytes confer protective effects via autocrine and paracrine mechanisms. Neurochem Int 61(1):89–99
-
(2012)
Neurochem Int
, vol.61
, Issue.1
, pp. 89-99
-
-
Shin, J.H.1
Kim, S.W.2
Jin, Y.3
Kim, I.D.4
Lee, J.K.5
-
79
-
-
51349142546
-
Ethyl pyruvate has an anti-inflammatory effect by inhibiting ROS-dependent STAT signaling in activated microglia
-
COI: 1:CAS:528:DC%2BD1cXhtFamsbfJ, PID: 18625301
-
Kim HS, Cho IH, Kim JE, Shin YJ, Jeon JH, Kim Y, Yang YM, Lee KH et al (2008) Ethyl pyruvate has an anti-inflammatory effect by inhibiting ROS-dependent STAT signaling in activated microglia. Free Radic Biol Med 45(7):950–963
-
(2008)
Free Radic Biol Med
, vol.45
, Issue.7
, pp. 950-963
-
-
Kim, H.S.1
Cho, I.H.2
Kim, J.E.3
Shin, Y.J.4
Jeon, J.H.5
Kim, Y.6
Yang, Y.M.7
Lee, K.H.8
-
80
-
-
26444558061
-
Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window
-
COI: 1:CAS:528:DC%2BD2MXhtVeisbnE, PID: 16141417
-
Yu YM, Kim JB, Lee KW, Kim SY, Han PL, Lee JK (2005) Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window. Stroke 36(10):2238–2243
-
(2005)
Stroke
, vol.36
, Issue.10
, pp. 2238-2243
-
-
Yu, Y.M.1
Kim, J.B.2
Lee, K.W.3
Kim, S.Y.4
Han, P.L.5
Lee, J.K.6
-
81
-
-
79952620639
-
Inhibitory mechanism of MMP-9 gene expression by ethyl pyruvate in lipopolysaccharide-stimulated BV2 microglial cells
-
COI: 1:CAS:528:DC%2BC3MXjtFGit7g%3D, PID: 21316417
-
Lee EJ, Kim HS (2011) Inhibitory mechanism of MMP-9 gene expression by ethyl pyruvate in lipopolysaccharide-stimulated BV2 microglial cells. Neurosci Lett 493(1–2):38–43
-
(2011)
Neurosci Lett
, vol.493
, Issue.1-2
, pp. 38-43
-
-
Lee, E.J.1
Kim, H.S.2
-
82
-
-
27444434090
-
NTP Toxicology and Carcinogenesis Studies of t-Butylhydroquinone (CAS No. 1948-33-0) in F344/N Rats and B6C3F(1) Mice (Feed Studies)
-
National Toxicology P (1997) NTP Toxicology and Carcinogenesis Studies of t-Butylhydroquinone (CAS No. 1948-33-0) in F344/N Rats and B6C3F(1) Mice (Feed Studies). Natl Toxicol Program Tech Rep Ser 459:1–326
-
(1997)
Natl Toxicol Program Tech Rep Ser
, vol.459
, pp. 1-326
-
-
National Toxicology, P.1
-
83
-
-
84866522881
-
The nuclear factor erythroid 2-like 2 activator, tert-butylhydroquinone, improves cognitive performance in mice after mild traumatic brain injury
-
COI: 1:CAS:528:DC%2BC38XhsVSnsLnO, PID: 22890082
-
Saykally JN, Rachmany L, Hatic H, Shaer A, Rubovitch V, Pick CG, Citron BA (2012) The nuclear factor erythroid 2-like 2 activator, tert-butylhydroquinone, improves cognitive performance in mice after mild traumatic brain injury. Neuroscience 223:305–314
-
(2012)
Neuroscience
, vol.223
, pp. 305-314
-
-
Saykally, J.N.1
Rachmany, L.2
Hatic, H.3
Shaer, A.4
Rubovitch, V.5
Pick, C.G.6
Citron, B.A.7
-
84
-
-
84901366903
-
Tert-butylhydroquinone alleviates early brain injury and cognitive dysfunction after experimental subarachnoid hemorrhage: role of Keap1/Nrf2/ARE pathway
-
PID: 24848277
-
Wang Z, Ji C, Wu L, Qiu J, Li Q, Shao Z, Chen G (2014) Tert-butylhydroquinone alleviates early brain injury and cognitive dysfunction after experimental subarachnoid hemorrhage: role of Keap1/Nrf2/ARE pathway. PLoS One 9(5), e97685
-
(2014)
PLoS One
, vol.9
, Issue.5
-
-
Wang, Z.1
Ji, C.2
Wu, L.3
Qiu, J.4
Li, Q.5
Shao, Z.6
Chen, G.7
-
85
-
-
0033835229
-
Early events in the induction of rat hepatic UDP-glucuronosyltransferases, glutathione S-transferase, and microsomal epoxide hydrolase by 1,7-phenanthroline: comparison with oltipraz, tert-butyl-4-hydroxyanisole, and tert-butylhydroquinone
-
COI: 1:CAS:528:DC%2BD3cXmtFCrtbo%3D, PID: 10950843
-
Lamb JG, Franklin MR (2000) Early events in the induction of rat hepatic UDP-glucuronosyltransferases, glutathione S-transferase, and microsomal epoxide hydrolase by 1,7-phenanthroline: comparison with oltipraz, tert-butyl-4-hydroxyanisole, and tert-butylhydroquinone. Drug Metab Dispos 28(9):1018–1023
-
(2000)
Drug Metab Dispos
, vol.28
, Issue.9
, pp. 1018-1023
-
-
Lamb, J.G.1
Franklin, M.R.2
-
86
-
-
0037446506
-
Pivotal role of electrophilicity in glutathione S-transferase induction by tert-butylhydroquinone
-
COI: 1:CAS:528:DC%2BD3sXit1Ojs7o%3D, PID: 12680784
-
Nakamura Y, Kumagai T, Yoshida C, Naito Y, Miyamoto M, Ohigashi H, Osawa T, Uchida K (2003) Pivotal role of electrophilicity in glutathione S-transferase induction by tert-butylhydroquinone. Biochemistry 42(14):4300–4309
-
(2003)
Biochemistry
, vol.42
, Issue.14
, pp. 4300-4309
-
-
Nakamura, Y.1
Kumagai, T.2
Yoshida, C.3
Naito, Y.4
Miyamoto, M.5
Ohigashi, H.6
Osawa, T.7
Uchida, K.8
-
87
-
-
17744408754
-
Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells
-
COI: 1:CAS:528:DC%2BD3sXms12hs7w%3D, PID: 12948865
-
Munzel PA, Schmohl S, Buckler F, Jaehrling J, Raschko FT, Kohle C, Bock KW (2003) Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells. Biochem Pharmacol 66(5):841–847
-
(2003)
Biochem Pharmacol
, vol.66
, Issue.5
, pp. 841-847
-
-
Munzel, P.A.1
Schmohl, S.2
Buckler, F.3
Jaehrling, J.4
Raschko, F.T.5
Kohle, C.6
Bock, K.W.7
-
88
-
-
13644268144
-
Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells
-
COI: 1:CAS:528:DC%2BD2MXisVWluw%3D%3D, PID: 15525690
-
Li J, Johnson D, Calkins M, Wright L, Svendsen C, Johnson J (2005) Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells. Toxicol Sci 83(2):313–328
-
(2005)
Toxicol Sci
, vol.83
, Issue.2
, pp. 313-328
-
-
Li, J.1
Johnson, D.2
Calkins, M.3
Wright, L.4
Svendsen, C.5
Johnson, J.6
-
89
-
-
33645945014
-
Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications
-
COI: 1:CAS:528:DC%2BD28Xktlylu7k%3D, PID: 16601269
-
Ryter SW, Alam J, Choi AM (2006) Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev 86(2):583–650
-
(2006)
Physiol Rev
, vol.86
, Issue.2
, pp. 583-650
-
-
Ryter, S.W.1
Alam, J.2
Choi, A.M.3
-
90
-
-
0029971924
-
Permanent focal and transient global cerebral ischemia increase glial and neuronal expression of heme oxygenase-1, but not heme oxygenase-2, protein in rat brain
-
COI: 1:CAS:528:DyaK28Xjs1Wqs7g%3D, PID: 8805131
-
Geddes JW, Pettigrew LC, Holtz ML, Craddock SD, Maines MD (1996) Permanent focal and transient global cerebral ischemia increase glial and neuronal expression of heme oxygenase-1, but not heme oxygenase-2, protein in rat brain. Neurosci Lett 210(3):205–208
-
(1996)
Neurosci Lett
, vol.210
, Issue.3
, pp. 205-208
-
-
Geddes, J.W.1
Pettigrew, L.C.2
Holtz, M.L.3
Craddock, S.D.4
Maines, M.D.5
-
91
-
-
32144460313
-
Expression of heme oxygenase-1 protein and messenger RNA in permanent cerebral ischemia in rats
-
COI: 1:CAS:528:DC%2BD28XhvVCrsb4%3D, PID: 16464361
-
Fu R, Zhao ZQ, Zhao HY, Zhao JS, Zhu XL (2006) Expression of heme oxygenase-1 protein and messenger RNA in permanent cerebral ischemia in rats. Neurol Res 28(1):38–45
-
(2006)
Neurol Res
, vol.28
, Issue.1
, pp. 38-45
-
-
Fu, R.1
Zhao, Z.Q.2
Zhao, H.Y.3
Zhao, J.S.4
Zhu, X.L.5
-
92
-
-
0035126635
-
Heme oxygenase-1 (HSP-32) and heme oxygenase-2 induction in neurons and glial cells of cerebral regions and its relation to iron accumulation after focal cortical photothrombosis
-
COI: 1:CAS:528:DC%2BD3MXhtV2gur0%3D, PID: 11170717
-
Bidmon HJ, Emde B, Oermann E, Kubitz R, Witte OW, Zilles K (2001) Heme oxygenase-1 (HSP-32) and heme oxygenase-2 induction in neurons and glial cells of cerebral regions and its relation to iron accumulation after focal cortical photothrombosis. Exp Neurol 168(1):1–22
-
(2001)
Exp Neurol
, vol.168
, Issue.1
, pp. 1-22
-
-
Bidmon, H.J.1
Emde, B.2
Oermann, E.3
Kubitz, R.4
Witte, O.W.5
Zilles, K.6
-
93
-
-
58149339691
-
Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury
-
PID: 18845796
-
Saleem S, Zhuang H, Biswal S, Christen Y, Dore S (2008) Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury. Stroke 39(12):3389–3396
-
(2008)
Stroke
, vol.39
, Issue.12
, pp. 3389-3396
-
-
Saleem, S.1
Zhuang, H.2
Biswal, S.3
Christen, Y.4
Dore, S.5
-
94
-
-
79953181232
-
Heme oxygenase 1, beneficial role in permanent ischemic stroke and in Gingko biloba (EGb 761) neuroprotection
-
COI: 1:CAS:528:DC%2BC3MXktF2gtro%3D, PID: 21334424
-
Shah ZA, Nada SE, Dore S (2011) Heme oxygenase 1, beneficial role in permanent ischemic stroke and in Gingko biloba (EGb 761) neuroprotection. Neuroscience 180:248–255
-
(2011)
Neuroscience
, vol.180
, pp. 248-255
-
-
Shah, Z.A.1
Nada, S.E.2
Dore, S.3
-
95
-
-
84860217385
-
Pharmacological induction of heme oxygenase-1 by a triterpenoid protects neurons against ischemic injury
-
COI: 1:CAS:528:DC%2BC38XmtVGlsrw%3D, PID: 22461332
-
Zhang F, Wang S, Zhang M, Weng Z, Li P, Gan Y, Zhang L, Cao G et al (2012) Pharmacological induction of heme oxygenase-1 by a triterpenoid protects neurons against ischemic injury. Stroke 43(5):1390–1397
-
(2012)
Stroke
, vol.43
, Issue.5
, pp. 1390-1397
-
-
Zhang, F.1
Wang, S.2
Zhang, M.3
Weng, Z.4
Li, P.5
Gan, Y.6
Zhang, L.7
Cao, G.8
-
96
-
-
80052420822
-
Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia
-
COI: 1:CAS:528:DC%2BC3MXht1CksLbN, PID: 21852618
-
Wang B, Cao W, Biswal S, Dore S (2011) Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia. Stroke 42(9):2605–2610
-
(2011)
Stroke
, vol.42
, Issue.9
, pp. 2605-2610
-
-
Wang, B.1
Cao, W.2
Biswal, S.3
Dore, S.4
-
97
-
-
33746051675
-
Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643
-
COI: 1:CAS:528:DC%2BD28XntlCqt7o%3D, PID: 16863991
-
Collino M, Aragno M, Mastrocola R, Benetti E, Gallicchio M, Dianzani C, Danni O, Thiemermann C et al (2006) Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643. Free Radic Biol Med 41(4):579–589
-
(2006)
Free Radic Biol Med
, vol.41
, Issue.4
, pp. 579-589
-
-
Collino, M.1
Aragno, M.2
Mastrocola, R.3
Benetti, E.4
Gallicchio, M.5
Dianzani, C.6
Danni, O.7
Thiemermann, C.8
-
98
-
-
28844471992
-
Molecular mechanisms involved in enhancing HO-1 expression: de-repression by heme and activation by Nrf2, the "one-two" punch
-
COI: 1:CAS:528:DC%2BD2MXhtlWht73O, PID: 16356129
-
Srisook K, Kim C, Cha YN (2005) Molecular mechanisms involved in enhancing HO-1 expression: de-repression by heme and activation by Nrf2, the "one-two" punch. Antioxid Redox Signal 7(11–12):1674–1687
-
(2005)
Antioxid Redox Signal
, vol.7
, Issue.11-12
, pp. 1674-1687
-
-
Srisook, K.1
Kim, C.2
Cha, Y.N.3
-
99
-
-
33644643191
-
The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation
-
COI: 1:CAS:528:DC%2BD28XhsFOqt7w%3D, PID: 16487043
-
Igarashi K, Sun J (2006) The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation. Antioxid Redox Signal 8(1–2):107–118
-
(2006)
Antioxid Redox Signal
, vol.8
, Issue.1-2
, pp. 107-118
-
-
Igarashi, K.1
Sun, J.2
-
100
-
-
81155126130
-
Novel insights into the regulation of antioxidant-response-element-mediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2
-
COI: 1:CAS:528:DC%2BC3MXhsVGkurrF, PID: 21812759
-
Jyrkkanen HK, Kuosmanen S, Heinaniemi M, Laitinen H, Kansanen E, Mella-Aho E, Leinonen H, Yla-Herttuala S et al (2011) Novel insights into the regulation of antioxidant-response-element-mediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2. Biochem J 440(2):167–174
-
(2011)
Biochem J
, vol.440
, Issue.2
, pp. 167-174
-
-
Jyrkkanen, H.K.1
Kuosmanen, S.2
Heinaniemi, M.3
Laitinen, H.4
Kansanen, E.5
Mella-Aho, E.6
Leinonen, H.7
Yla-Herttuala, S.8
-
101
-
-
84876992081
-
Induction of hemeoxygenase-1 expression after inhibition of hemeoxygenase activity promotes inflammation and worsens ischemic brain damage in mice
-
COI: 1:CAS:528:DC%2BC3sXnslart74%3D, PID: 23562577
-
Perez-de-Puig I, Martin A, Gorina R, de la Rosa X, Martinez E, Planas AM (2013) Induction of hemeoxygenase-1 expression after inhibition of hemeoxygenase activity promotes inflammation and worsens ischemic brain damage in mice. Neuroscience 243:22–32
-
(2013)
Neuroscience
, vol.243
, pp. 22-32
-
-
Perez-de-Puig, I.1
Martin, A.2
Gorina, R.3
de la Rosa, X.4
Martinez, E.5
Planas, A.M.6
-
102
-
-
34250782407
-
Heme oxygenase-1 exacerbates early brain injury after intracerebral haemorrhage
-
PID: 17525142
-
Wang J, Dore S (2007) Heme oxygenase-1 exacerbates early brain injury after intracerebral haemorrhage. Brain 130(Pt 6):1643–1652
-
(2007)
Brain
, vol.130
, pp. 1643-1652
-
-
Wang, J.1
Dore, S.2
-
103
-
-
34547135735
-
Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress
-
COI: 1:CAS:528:DC%2BD2sXnsFWmsr8%3D, PID: 17430897
-
Lin Q, Weis S, Yang G, Weng YH, Helston R, Rish K, Smith A, Bordner J et al (2007) Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress. J Biol Chem 282(28):20621–20633
-
(2007)
J Biol Chem
, vol.282
, Issue.28
, pp. 20621-20633
-
-
Lin, Q.1
Weis, S.2
Yang, G.3
Weng, Y.H.4
Helston, R.5
Rish, K.6
Smith, A.7
Bordner, J.8
-
104
-
-
84876221752
-
Time course of Keap1-Nrf2 pathway expression after experimental intracerebral haemorrhage: correlation with brain oedema and neurological deficit
-
COI: 1:CAS:528:DC%2BC3sXlslyku7c%3D, PID: 23438812
-
Shang H, Yang D, Zhang W, Li T, Ren X, Wang X, Zhao W (2013) Time course of Keap1-Nrf2 pathway expression after experimental intracerebral haemorrhage: correlation with brain oedema and neurological deficit. Free Radic Res 47(5):368–375
-
(2013)
Free Radic Res
, vol.47
, Issue.5
, pp. 368-375
-
-
Shang, H.1
Yang, D.2
Zhang, W.3
Li, T.4
Ren, X.5
Wang, X.6
Zhao, W.7
-
105
-
-
77956171147
-
NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector
-
COI: 1:CAS:528:DC%2BC3cXhtV2jur7L, PID: 20361926
-
Dinkova-Kostova AT, Talalay P (2010) NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector. Arch Biochem Biophys 501(1):116–123
-
(2010)
Arch Biochem Biophys
, vol.501
, Issue.1
, pp. 116-123
-
-
Dinkova-Kostova, A.T.1
Talalay, P.2
-
106
-
-
1442324843
-
Presence and induction of the enzyme NAD(P)H: quinone oxidoreductase 1 in the central nervous system
-
COI: 1:CAS:528:DC%2BD2cXjtVCqtL0%3D, PID: 14991562
-
Stringer JL, Gaikwad A, Gonzales BN, Long DJ Jr, Marks LM, Jaiswal AK (2004) Presence and induction of the enzyme NAD(P)H: quinone oxidoreductase 1 in the central nervous system. J Comp Neurol 471(3):289–297
-
(2004)
J Comp Neurol
, vol.471
, Issue.3
, pp. 289-297
-
-
Stringer, J.L.1
Gaikwad, A.2
Gonzales, B.N.3
Long, D.J.4
Marks, L.M.5
Jaiswal, A.K.6
-
107
-
-
84878971174
-
Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins
-
COI: 1:CAS:528:DC%2BC3sXovVCntLY%3D, PID: 23692925
-
Dong H, Shertzer HG, Genter MB, Gonzalez FJ, Vasiliou V, Jefcoate C, Nebert DW (2013) Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins. Biochem Biophys Res Commun 435(4):727–732
-
(2013)
Biochem Biophys Res Commun
, vol.435
, Issue.4
, pp. 727-732
-
-
Dong, H.1
Shertzer, H.G.2
Genter, M.B.3
Gonzalez, F.J.4
Vasiliou, V.5
Jefcoate, C.6
Nebert, D.W.7
-
108
-
-
84863041323
-
Assurance of mitochondrial integrity and mammalian longevity by the p62-Keap1-Nrf2-Nqo1 cascade
-
COI: 1:CAS:528:DC%2BC38XlsF2juw%3D%3D, PID: 22222206
-
Kwon J, Han E, Bui CB, Shin W, Lee J, Lee S, Choi YB, Lee AH et al (2012) Assurance of mitochondrial integrity and mammalian longevity by the p62-Keap1-Nrf2-Nqo1 cascade. EMBO Rep 13(2):150–156
-
(2012)
EMBO Rep
, vol.13
, Issue.2
, pp. 150-156
-
-
Kwon, J.1
Han, E.2
Bui, C.B.3
Shin, W.4
Lee, J.5
Lee, S.6
Choi, Y.B.7
Lee, A.H.8
-
109
-
-
84875501916
-
Neuroprotection by curcumin in ischemic brain injury involves the Akt/Nrf2 pathway
-
COI: 1:CAS:528:DC%2BC3sXmtVenur8%3D, PID: 23555802
-
Wu J, Li Q, Wang X, Yu S, Li L, Wu X, Chen Y, Zhao J et al (2013) Neuroprotection by curcumin in ischemic brain injury involves the Akt/Nrf2 pathway. PLoS One 8(3), e59843
-
(2013)
PLoS One
, vol.8
, Issue.3
-
-
Wu, J.1
Li, Q.2
Wang, X.3
Yu, S.4
Li, L.5
Wu, X.6
Chen, Y.7
Zhao, J.8
-
110
-
-
84906729674
-
Sevoflurane postconditioning attenuates cerebral ischemia-reperfusion injury via protein kinase B/nuclear factor-erythroid 2-related factor 2 pathway activation
-
Li B, Sun J, Lv G, Yu Y, Wang G, Xie K, Jiao Y, Yu Y (2014) Sevoflurane postconditioning attenuates cerebral ischemia-reperfusion injury via protein kinase B/nuclear factor-erythroid 2-related factor 2 pathway activation. Int J Dev Neurosci 38C:79–86
-
(2014)
Int J Dev Neurosci
, vol.38C
, pp. 79-86
-
-
Li, B.1
Sun, J.2
Lv, G.3
Yu, Y.4
Wang, G.5
Xie, K.6
Jiao, Y.7
Yu, Y.8
-
111
-
-
0035890484
-
Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily
-
COI: 1:CAS:528:DC%2BD3MXovVClt7w%3D, PID: 11695986
-
Sheehan D, Meade G, Foley VM, Dowd CA (2001) Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily. Biochem J 360(Pt 1):1–16
-
(2001)
Biochem J
, vol.360
, pp. 1-16
-
-
Sheehan, D.1
Meade, G.2
Foley, V.M.3
Dowd, C.A.4
-
113
-
-
0033956744
-
The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin
-
COI: 1:CAS:528:DC%2BD3cXhsVKqtr4%3D, PID: 10816095
-
Hayes JD, Chanas SA, Henderson CJ, McMahon M, Sun C, Moffat GJ, Wolf CR, Yamamoto M (2000) The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin. Biochem Soc Trans 28(2):33–41
-
(2000)
Biochem Soc Trans
, vol.28
, Issue.2
, pp. 33-41
-
-
Hayes, J.D.1
Chanas, S.A.2
Henderson, C.J.3
McMahon, M.4
Sun, C.5
Moffat, G.J.6
Wolf, C.R.7
Yamamoto, M.8
-
114
-
-
84902152605
-
Ischemic stroke injury is mediated by aberrant Cdk5
-
PID: 24920629
-
Meyer DA, Torres-Altoro MI, Tan Z, Tozzi A, Di Filippo M, DiNapoli V, Plattner F, Kansy JW et al (2014) Ischemic stroke injury is mediated by aberrant Cdk5. J Neurosci 34(24):8259–8267
-
(2014)
J Neurosci
, vol.34
, Issue.24
, pp. 8259-8267
-
-
Meyer, D.A.1
Torres-Altoro, M.I.2
Tan, Z.3
Tozzi, A.4
Di Filippo, M.5
DiNapoli, V.6
Plattner, F.7
Kansy, J.W.8
-
116
-
-
79551686173
-
Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione S-transferases in mouse liver
-
COI: 1:CAS:528:DC%2BC3cXkvVOgtbs%3D, PID: 20118494
-
Giera S, Braeuning A, Kohle C, Bursch W, Metzger U, Buchmann A, Schwarz M (2010) Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione S-transferases in mouse liver. Toxicol Sci 115(1):22–33
-
(2010)
Toxicol Sci
, vol.115
, Issue.1
, pp. 22-33
-
-
Giera, S.1
Braeuning, A.2
Kohle, C.3
Bursch, W.4
Metzger, U.5
Buchmann, A.6
Schwarz, M.7
-
117
-
-
67649670106
-
Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia
-
COI: 1:CAS:528:DC%2BD1MXotl2ltLo%3D, PID: 19445907
-
Yang C, Zhang X, Fan H, Liu Y (2009) Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia. Brain Res 1282:133–141
-
(2009)
Brain Res
, vol.1282
, pp. 133-141
-
-
Yang, C.1
Zhang, X.2
Fan, H.3
Liu, Y.4
-
118
-
-
78651349039
-
Expression of Keap1-Nrf2 system and antioxidative proteins in mouse brain after transient middle cerebral artery occlusion
-
COI: 1:CAS:528:DC%2BC3MXktFShtg%3D%3D, PID: 21075092
-
Tanaka N, Ikeda Y, Ohta Y, Deguchi K, Tian F, Shang J, Matsuura T, Abe K (2011) Expression of Keap1-Nrf2 system and antioxidative proteins in mouse brain after transient middle cerebral artery occlusion. Brain Res 1370:246–253
-
(2011)
Brain Res
, vol.1370
, pp. 246-253
-
-
Tanaka, N.1
Ikeda, Y.2
Ohta, Y.3
Deguchi, K.4
Tian, F.5
Shang, J.6
Matsuura, T.7
Abe, K.8
-
119
-
-
84910660896
-
Radionuclide Imaging in Ischemic Stroke
-
Heiss WD (2014) Radionuclide Imaging in Ischemic Stroke. J Nucl Med
-
(2014)
J Nucl Med
-
-
Heiss, W.D.1
-
120
-
-
84859141362
-
Nrf2 expression by neurons, astroglia, and microglia in the cerebral cortical penumbra of ischemic rats
-
COI: 1:CAS:528:DC%2BC38XisVygtLk%3D, PID: 21932039
-
Dang J, Brandenburg LO, Rosen C, Fragoulis A, Kipp M, Pufe T, Beyer C, Wruck CJ (2012) Nrf2 expression by neurons, astroglia, and microglia in the cerebral cortical penumbra of ischemic rats. J Mol Neurosci 46(3):578–584
-
(2012)
J Mol Neurosci
, vol.46
, Issue.3
, pp. 578-584
-
-
Dang, J.1
Brandenburg, L.O.2
Rosen, C.3
Fragoulis, A.4
Kipp, M.5
Pufe, T.6
Beyer, C.7
Wruck, C.J.8
-
121
-
-
0033817826
-
BIT/SHPS-1 enhances brain-derived neurotrophic factor-promoted neuronal survival in cultured cerebral cortical neurons
-
COI: 1:CAS:528:DC%2BD3cXmslGltrk%3D, PID: 10987830
-
Araki T, Yamada M, Ohnishi H, Sano SI, Hatanaka H (2000) BIT/SHPS-1 enhances brain-derived neurotrophic factor-promoted neuronal survival in cultured cerebral cortical neurons. J Neurochem 75(4):1502–1510
-
(2000)
J Neurochem
, vol.75
, Issue.4
, pp. 1502-1510
-
-
Araki, T.1
Yamada, M.2
Ohnishi, H.3
Sano, S.I.4
Hatanaka, H.5
-
122
-
-
84864120317
-
SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress
-
COI: 1:CAS:528:DC%2BC38XhtFeit77K, PID: 22671569
-
Wang L, Lu Y, Deng S, Zhang Y, Yang L, Guan Y, Matozaki T, Ohnishi H et al (2012) SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress. J Neurochem 122(4):834–843
-
(2012)
J Neurochem
, vol.122
, Issue.4
, pp. 834-843
-
-
Wang, L.1
Lu, Y.2
Deng, S.3
Zhang, Y.4
Yang, L.5
Guan, Y.6
Matozaki, T.7
Ohnishi, H.8
-
123
-
-
33644700591
-
Risk factors for subarachnoid hemorrhage: an updated systematic review of epidemiological studies
-
PID: 16282541
-
Feigin VL, Rinkel GJ, Lawes CM, Algra A, Bennett DA, van Gijn J, Anderson CS (2005) Risk factors for subarachnoid hemorrhage: an updated systematic review of epidemiological studies. Stroke 36(12):2773–2780
-
(2005)
Stroke
, vol.36
, Issue.12
, pp. 2773-2780
-
-
Feigin, V.L.1
Rinkel, G.J.2
Lawes, C.M.3
Algra, A.4
Bennett, D.A.5
van Gijn, J.6
Anderson, C.S.7
-
124
-
-
36448945858
-
Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage
-
COI: 1:CAS:528:DC%2BD2sXhtlSlt7jN, PID: 17962605
-
Zhao X, Sun G, Zhang J, Strong R, Dash PK, Kan YW, Grotta JC, Aronowski J (2007) Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. Stroke 38(12):3280–3286
-
(2007)
Stroke
, vol.38
, Issue.12
, pp. 3280-3286
-
-
Zhao, X.1
Sun, G.2
Zhang, J.3
Strong, R.4
Dash, P.K.5
Kan, Y.W.6
Grotta, J.C.7
Aronowski, J.8
-
125
-
-
34250854714
-
Role of Nrf2 in protection against intracerebral hemorrhage injury in mice
-
PID: 17602956
-
Wang J, Fields J, Zhao C, Langer J, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S et al (2007) Role of Nrf2 in protection against intracerebral hemorrhage injury in mice. Free Radic Biol Med 43(3):408–414
-
(2007)
Free Radic Biol Med
, vol.43
, Issue.3
, pp. 408-414
-
-
Wang, J.1
Fields, J.2
Zhao, C.3
Langer, J.4
Thimmulappa, R.K.5
Kensler, T.W.6
Yamamoto, M.7
Biswal, S.8
-
126
-
-
84925466430
-
Cleaning up after ICH: the role of Nrf2 in modulating microglia function and hematoma clearance
-
Zhao X, Sun G, Ting SM, Song S, Zhang J, Edwards NJ, Aronowski J (2014) Cleaning up after ICH: the role of Nrf2 in modulating microglia function and hematoma clearance. J Neurochem
-
(2014)
J Neurochem
-
-
Zhao, X.1
Sun, G.2
Ting, S.M.3
Song, S.4
Zhang, J.5
Edwards, N.J.6
Aronowski, J.7
-
127
-
-
33750350414
-
Mechanisms of early brain injury after subarachnoid hemorrhage
-
COI: 1:CAS:528:DC%2BD28Xht1Wjt7fN, PID: 16482081
-
Cahill J, Calvert JW, Zhang JH (2006) Mechanisms of early brain injury after subarachnoid hemorrhage. J Cereb Blood Flow Metab 26(11):1341–1353
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, Issue.11
, pp. 1341-1353
-
-
Cahill, J.1
Calvert, J.W.2
Zhang, J.H.3
-
128
-
-
77956259261
-
Murine neural stem/progenitor cells protect neurons against ischemia by HIF-1alpha-regulated VEGF signaling
-
PID: 20339541
-
Harms KM, Li L, Cunningham LA (2010) Murine neural stem/progenitor cells protect neurons against ischemia by HIF-1alpha-regulated VEGF signaling. PLoS One 5(3), e9767
-
(2010)
PLoS One
, vol.5
, Issue.3
-
-
Harms, K.M.1
Li, L.2
Cunningham, L.A.3
-
129
-
-
84857873046
-
Minocycline-preconditioned neural stem cells enhance neuroprotection after ischemic stroke in rats
-
COI: 1:CAS:528:DC%2BC38XjvFyntbs%3D, PID: 22399769
-
Sakata H, Niizuma K, Yoshioka H, Kim GS, Jung JE, Katsu M, Narasimhan P, Maier CM et al (2012) Minocycline-preconditioned neural stem cells enhance neuroprotection after ischemic stroke in rats. J Neurosci 32(10):3462–3473
-
(2012)
J Neurosci
, vol.32
, Issue.10
, pp. 3462-3473
-
-
Sakata, H.1
Niizuma, K.2
Yoshioka, H.3
Kim, G.S.4
Jung, J.E.5
Katsu, M.6
Narasimhan, P.7
Maier, C.M.8
-
130
-
-
77956640097
-
Regulation of notch1 signaling by nrf2: implications for tissue regeneration
-
Wakabayashi N, Shin S, Slocum SL, Agoston ES, Wakabayashi J, Kwak MK, Misra V, Biswal S et al (2010) Regulation of notch1 signaling by nrf2: implications for tissue regeneration. Sci Signal 3(ra52)
-
(2010)
Sci Signal
, vol.3
, Issue.ra52
-
-
Wakabayashi, N.1
Shin, S.2
Slocum, S.L.3
Agoston, E.S.4
Wakabayashi, J.5
Kwak, M.K.6
Misra, V.7
Biswal, S.8
-
131
-
-
84875269241
-
Doxycycline can stimulate cytoprotection in neural stem cells with oxygen-glucose deprivation-reoxygenation injury: a potential approach to enhance effectiveness of cell transplantation therapy
-
COI: 1:CAS:528:DC%2BC3sXjtFSktbk%3D, PID: 23395678
-
Malik YS, Sheikh MA, Zhu X (2013) Doxycycline can stimulate cytoprotection in neural stem cells with oxygen-glucose deprivation-reoxygenation injury: a potential approach to enhance effectiveness of cell transplantation therapy. Biochem Biophys Res Commun 432(2):355–358
-
(2013)
Biochem Biophys Res Commun
, vol.432
, Issue.2
, pp. 355-358
-
-
Malik, Y.S.1
Sheikh, M.A.2
Zhu, X.3
-
132
-
-
65549106019
-
Ischemic postconditioning as a novel avenue to protect against brain injury after stroke
-
COI: 1:CAS:528:DC%2BD1MXlt1SksL8%3D, PID: 19240739
-
Zhao H (2009) Ischemic postconditioning as a novel avenue to protect against brain injury after stroke. J Cereb Blood Flow Metab 29(5):873–885
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, Issue.5
, pp. 873-885
-
-
Zhao, H.1
-
133
-
-
84866742957
-
Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke
-
COI: 1:CAS:528:DC%2BC38XhsVWmt7zK, PID: 22910893
-
Hoda MN, Siddiqui S, Herberg S, Periyasamy-Thandavan S, Bhatia K, Hafez SS, Johnson MH, Hill WD et al (2012) Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke. Stroke 43(10):2794–2799
-
(2012)
Stroke
, vol.43
, Issue.10
, pp. 2794-2799
-
-
Hoda, M.N.1
Siddiqui, S.2
Herberg, S.3
Periyasamy-Thandavan, S.4
Bhatia, K.5
Hafez, S.S.6
Johnson, M.H.7
Hill, W.D.8
-
134
-
-
84901331391
-
Protective effects of remote ischemic conditioning against ischemia/reperfusion-induced retinal injury in rats
-
COI: 1:CAS:528:DC%2BC2cXitVOhu7rI, PID: 24735565
-
Zhang X, Jizhang Y, Xu X, Kwiecien TD, Li N, Zhang Y, Ji X, Ren C et al (2014) Protective effects of remote ischemic conditioning against ischemia/reperfusion-induced retinal injury in rats. Vis Neurosci 31(3):245–252
-
(2014)
Vis Neurosci
, vol.31
, Issue.3
, pp. 245-252
-
-
Zhang, X.1
Jizhang, Y.2
Xu, X.3
Kwiecien, T.D.4
Li, N.5
Zhang, Y.6
Ji, X.7
Ren, C.8
|