메뉴 건너뛰기




Volumn 43, Issue 5, 2012, Pages 1390-1397

Pharmacological induction of heme oxygenase-1 by a triterpenoid protects neurons against ischemic injury

Author keywords

CDDO; Cytoprotective; Nrf2; Stroke

Indexed keywords

2 CYANO 3,12 DIOXOOLEANA 1,9 DIEN 28 YL IMIDAZOLINE; GLUCOSE; HEME OXYGENASE 1; NEUROPROTECTIVE AGENT; OXYGEN; PROTOPORPHYRIN TIN; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR NRF2; TRITERPENOID; UNCLASSIFIED DRUG;

EID: 84860217385     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.647420     Document Type: Article
Times cited : (79)

References (29)
  • 1
    • 19444386445 scopus 로고    scopus 로고
    • Free heme toxicity and its detoxification systems in human
    • DOI 10.1016/j.toxlet.2005.03.004, PII S0378427405000883
    • Kumar S, Bandyopadhyay U. Free heme toxicity and its detoxification systems in human. Toxicol Lett. 2005;157:175-188. (Pubitemid 40726102)
    • (2005) Toxicology Letters , vol.157 , Issue.3 , pp. 175-188
    • Kumar, S.1    Bandyopadhyay, U.2
  • 2
    • 0032972686 scopus 로고    scopus 로고
    • Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice
    • Panahian N, Yoshiura M, Maines MD. Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice. J Neurochem. 1999;72:1187-1203. (Pubitemid 29085035)
    • (1999) Journal of Neurochemistry , vol.72 , Issue.3 , pp. 1187-1203
    • Panahian, N.1    Yoshiura, M.2    Maines, M.D.3
  • 4
    • 0842304134 scopus 로고    scopus 로고
    • Nuclear Factor E2-Related Factor 2-Dependent Antioxidant Response Element Activation by tert-Butylhydroquinone and Sulforaphane Occurring Preferentially in Astrocytes Conditions Neurons against Oxidative Insult
    • DOI 10.1523/JNEUROSCI.3817-03.2004
    • Kraft AD, Johnson DA, Johnson JA. Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tertbutylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult. J Neurosci. 2004; 24:1101-1112. (Pubitemid 38177017)
    • (2004) Journal of Neuroscience , vol.24 , Issue.5 , pp. 1101-1112
    • Kraft, A.D.1    Johnson, D.A.2    Johnson, J.A.3
  • 5
    • 29244479186 scopus 로고    scopus 로고
    • Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents
    • DOI 10.1016/j.neulet.2005.09.065, PII S0304394005011146
    • Zhao J, Kobori N, Aronowski J, Dash PK. Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents. Neurosci Lett. 2006;393:108-112. (Pubitemid 41821089)
    • (2006) Neuroscience Letters , vol.393 , Issue.2-3 , pp. 108-112
    • Zhao, J.1    Kobori, N.2    Aronowski, J.3    Dash, P.K.4
  • 6
    • 36448945858 scopus 로고    scopus 로고
    • Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage
    • DOI 10.1161/STROKEAHA.107.486506, PII 0000767020071200000028
    • Zhao X, Sun G, Zhang J, Strong R, Dash PK, Kan YW, et al. Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. Stroke. 2007;38:3280-3286. (Pubitemid 350175749)
    • (2007) Stroke , vol.38 , Issue.12 , pp. 3280-3286
    • Zhao, X.1    Sun, G.2    Zhang, J.3    Strong, R.4    Dash, P.K.5    Kan, Y.W.6    Grotta, J.C.7    Aronowski, J.8
  • 7
    • 58149339691 scopus 로고    scopus 로고
    • Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury
    • Saleem S, Zhuang H, Biswal S, Christen Y, Dore S. Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury. Stroke. 2008;39:3389-3396.
    • (2008) Stroke , vol.39 , pp. 3389-3396
    • Saleem, S.1    Zhuang, H.2    Biswal, S.3    Christen, Y.4    Dore, S.5
  • 8
    • 79953181232 scopus 로고    scopus 로고
    • Heme oxygenase 1, beneficial role in permanent ischemic stroke and in gingko biloba (EGB 761) neuroprotection
    • Shah ZA, Nada SE, Dore S. Heme oxygenase 1, beneficial role in permanent ischemic stroke and in gingko biloba (EGB 761) neuroprotection. Neuroscience. 2011;180:248-255.
    • (2011) Neuroscience , vol.180 , pp. 248-255
    • Shah, Z.A.1    Nada, S.E.2    Dore, S.3
  • 9
    • 27744438478 scopus 로고    scopus 로고
    • A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo
    • DOI 10.1523/JNEUROSCI.4014-05.2005
    • Shih AY, Li P, Murphy TH. A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo. J Neurosci. 2005;25:10321-10335. (Pubitemid 41636229)
    • (2005) Journal of Neuroscience , vol.25 , Issue.44 , pp. 10321-10335
    • Shih, A.Y.1    Li, P.2    Murphy, T.H.3
  • 12
    • 79953242026 scopus 로고    scopus 로고
    • New synthetic triterpenoids: Potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress
    • Sporn MB, Liby KT, Yore MM, Fu L, Lopchuk JM, Gribble GW. New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress. J Nat Prod. 2010;74:537-545.
    • (2010) J Nat Prod , vol.74 , pp. 537-545
    • Sporn, M.B.1    Liby, K.T.2    Yore, M.M.3    Fu, L.4    Lopchuk, J.M.5    Gribble, G.W.6
  • 13
    • 0037041248 scopus 로고    scopus 로고
    • A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28- onitrile, active at picomolar concentrations for inhibition of nitric oxide production
    • DOI 10.1016/S0960-894X(02)00105-1, PII S0960894X02001051
    • Honda T, Honda Y, Favaloro FG, Jr., Gribble GW, Suh N, Place AE, et al. A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide production. Bioorg Med Chem Lett. 2002;12:1027-1030. (Pubitemid 34242794)
    • (2002) Bioorganic and Medicinal Chemistry Letters , vol.12 , Issue.7 , pp. 1027-1030
    • Honda, T.1    Honda, Y.2    Favaloro Jr., F.G.3    Gribble, G.W.4    Suh, N.5    Place, A.E.6    Rendi, M.H.7    Sporn, M.B.8
  • 16
    • 74049120454 scopus 로고    scopus 로고
    • Nrf2: Friend or foe for chemoprevention?
    • Kensler TW, Wakabayashi N. Nrf2: friend or foe for chemoprevention? Carcinogenesis. 2010;31:90-99.
    • (2010) Carcinogenesis , vol.31 , pp. 90-99
    • Kensler, T.W.1    Wakabayashi, N.2
  • 17
    • 79251609220 scopus 로고    scopus 로고
    • Synthetic triterpenoid CDDO derivatives modulate cytoprotective or immunological properties in astrocytes, neurons, and microglia
    • Graber DJ, Park PJ, Hickey WF, Harris BT. Synthetic triterpenoid CDDO derivatives modulate cytoprotective or immunological properties in astrocytes, neurons, and microglia. J Neuroimmune Pharmacol. 2010;6: 107-120.
    • (2010) J Neuroimmune Pharmacol , vol.6 , pp. 107-120
    • Graber, D.J.1    Park, P.J.2    Hickey, W.F.3    Harris, B.T.4
  • 18
    • 0034597578 scopus 로고    scopus 로고
    • Synthetic oleanane and ursane triterpenoids with modified rings a and c: A series of highly active inhibitors of nitric oxide production in mouse macrophages
    • Honda T, Rounds BV, Bore L, Finlay HJ, Favaloro FG Jr, Suh N, et al. Synthetic oleanane and ursane triterpenoids with modified rings a and c: a series of highly active inhibitors of nitric oxide production in mouse macrophages. J Med Chem. 2000;43:4233-4246.
    • (2000) J Med Chem , vol.43 , pp. 4233-4246
    • Honda, T.1    Rounds, B.V.2    Bore, L.3    Finlay, H.J.4    Favaloro Jr., F.G.5    Suh, N.6
  • 20
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
    • Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, et al. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal NEH2 domain. Genes Dev. 1999;13:76-86. (Pubitemid 29045117)
    • (1999) Genes and Development , vol.13 , Issue.1 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6    Yamamoto, M.7
  • 21
    • 58249117780 scopus 로고    scopus 로고
    • The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds
    • Kobayashi M, Li L, Iwamoto N, Nakajima-Takagi Y, Kaneko H, et al. The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. Mol Cell Biol. 2009;29:493-502.
    • (2009) Mol Cell Biol , vol.29 , pp. 493-502
    • Kobayashi, M.1    Li, L.2    Iwamoto, N.3    Nakajima-Takagi, Y.4    Kaneko, H.5
  • 22
    • 77954067261 scopus 로고    scopus 로고
    • Dihydro-CDDO-trifluoroethyl amide (DH404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes
    • Ichikawa T, Li J, Meyer CJ, Janicki JS, Hannink M, Cui T. Dihydro-CDDO-trifluoroethyl amide (DH404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes. PLoS One. 2009;4:e8391.
    • (2009) PLoS One , vol.4
    • Ichikawa, T.1    Li, J.2    Meyer, C.J.3    Janicki, J.S.4    Hannink, M.5    Cui, T.6
  • 23
    • 70349333698 scopus 로고    scopus 로고
    • The Nrf2-are cytoprotective pathway in astrocytes
    • Vargas MR, Johnson JA. The Nrf2-are cytoprotective pathway in astrocytes. Expert Rev Mol Med. 2009;11:e17.
    • (2009) Expert Rev Mol Med , vol.11
    • Vargas, M.R.1    Johnson, J.A.2
  • 24
    • 77957221943 scopus 로고    scopus 로고
    • Synthetic triterpenoids attenuate cytotoxic retinal injury: Cross-talk between Nrf2 and PI3K/Akt signaling through inhibition of the lipid phosphatase PTEN
    • Pitha-Rowe I, Liby K, Royce D, Sporn M. Synthetic triterpenoids attenuate cytotoxic retinal injury: cross-talk between Nrf2 and PI3K/Akt signaling through inhibition of the lipid phosphatase PTEN. Invest Ophthalmol Vis Sci. 2009;50:5339-5347.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 5339-5347
    • Pitha-Rowe, I.1    Liby, K.2    Royce, D.3    Sporn, M.4
  • 25
    • 62649115489 scopus 로고    scopus 로고
    • Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease
    • Dumont M, Wille E, Calingasan NY, Tampellini D, Williams C, Gouras GK, et al. Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease. J Neurochem. 2009;109:502-512.
    • (2009) J Neurochem , vol.109 , pp. 502-512
    • Dumont, M.1    Wille, E.2    Calingasan, N.Y.3    Tampellini, D.4    Williams, C.5    Gouras, G.K.6
  • 26
    • 66749132810 scopus 로고    scopus 로고
    • Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription
    • Yang L, Calingasan NY, Thomas B, Chaturvedi RK, Kiaei M, Wille EJ, et al. Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. PLoS One. 2009;4:e5757.
    • (2009) PLoS One , vol.4
    • Yang, L.1    Calingasan, N.Y.2    Thomas, B.3    Chaturvedi, R.K.4    Kiaei, M.5    Wille, E.J.6
  • 27
    • 79957959973 scopus 로고    scopus 로고
    • Neuroprotective effect of Nrf2/are activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis
    • Neymotin A, Calingasan NY, Wille E, Naseri N, Petri S, Damiano M, et al. Neuroprotective effect of Nrf2/are activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis. Free Radic Biol Med. 2011;51:88-96.
    • (2011) Free Radic Biol Med , vol.51 , pp. 88-96
    • Neymotin, A.1    Calingasan, N.Y.2    Wille, E.3    Naseri, N.4    Petri, S.5    Damiano, M.6
  • 29
    • 33845976705 scopus 로고    scopus 로고
    • Triterpenoid CDDO-Me blocks the NF-κB pathway by direct inhibition of IKKβ on Cys-179
    • DOI 10.1074/jbc.M607160200
    • Ahmad R, Raina D, Meyer C, Kharbanda S, Kufe D. Triterpenoid CDDO-ME blocks the NF-kappaB pathway by direct inhibition of IKKbeta on CYS-179. J Biol Chem. 2006;281:35764-35769. (Pubitemid 46041307)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.47 , pp. 35764-35769
    • Ahmad, R.1    Raina, D.2    Meyer, C.3    Kharbanda, S.4    Kufe, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.