Repeated transient sulforaphane stimulation in astrocytes leads to prolonged Nrf2-mediated gene expression and protection from superoxide-induced damage

Neuropharmacology

Volumn 60, Issue 2-3, 2011, Pages 343-353

  Bergström, Petra ^a   Andersson, Heléne C ^b   Gao, Yue ^a   Karlsson, Jan Olof ^b   Nodin, Christina ^b   Anderson, Michelle F ^b   Nilsson, Michael ^b   Hammarsten, Ola ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Astrocytes; Hmox1; Neuroprotection; Nqo1; Nrf2; Oxidative damage; Sulforaphane

Indexed keywords

GLUTATHIONE; HEME OXYGENASE 1; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SMALL INTERFERING RNA; SULFORAPHANE; SUPEROXIDE; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE FUNCTION; NERVE CELL; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELL DEATH; CELLS, CULTURED; FREE RADICALS; GENE EXPRESSION REGULATION; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SUPEROXIDES; THIOCYANATES;

EID: 78650814146     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2010.09.023     Document Type: Article

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