메뉴 건너뛰기




Volumn 10, Issue 12, 2015, Pages

Dual-specificity phosphatase 4 regulates STAT5 protein stability and helper T cell polarization

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; DUAL SPECIFICITY PHOSPHATASE; DUAL SPECIFICITY PHOSPHATASE 4; STAT5 PROTEIN; UNCLASSIFIED DRUG; HYBRID PROTEIN; MKP2 PROTEIN, MOUSE; PROTEIN TYROSINE PHOSPHATASE; STAT5A PROTEIN, MOUSE;

EID: 84957564551     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0145880     Document Type: Article
Times cited : (30)

References (60)
  • 1
    • 43049101029 scopus 로고    scopus 로고
    • Dual-specificity MAP kinase phosphatases (MKPs) and cancer
    • 18330678
    • Keyse SM. Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev. 2008; 27: 253-261. doi: 10.1007/s10555-008-9123-1 PMID: 18330678
    • (2008) Cancer Metastasis Rev. , vol.27 , pp. 253-261
    • Keyse, S.M.1
  • 2
    • 84864326726 scopus 로고    scopus 로고
    • DUSPs, to MAP kinases and beyond
    • 22769588
    • Huang CY, Tan TH. DUSPs, to MAP kinases and beyond. Cell Biosci. 2012; 2: 24. doi: 10.1186/2045-3701-2-24 PMID: 22769588
    • (2012) Cell Biosci. , vol.2 , pp. 24
    • Huang, C.Y.1    Tan, T.H.2
  • 3
    • 84894120177 scopus 로고    scopus 로고
    • The family-wide structure and function of human dual-specificity protein phosphatases
    • 24531476
    • Jeong DG, Wei CH, Ku B, Jeon TJ, Chien PN, Kim JK, et al. The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr D Biol Crystallogr. 2014; 70: 421-435. doi: 10.1107/S1399004713029866 PMID: 24531476
    • (2014) Acta Crystallogr D Biol Crystallogr. , vol.70 , pp. 421-435
    • Jeong, D.G.1    Wei, C.H.2    Ku, B.3    Jeon, T.J.4    Chien, P.N.5    Kim, J.K.6
  • 4
    • 0028921905 scopus 로고
    • Isolation and characterization of a novel dual specific phosphatase, HVH2, which selectively dephosphorylates the mitogen-activated protein kinase
    • 7535768
    • Guan KL, Butch E. Isolation and characterization of a novel dual specific phosphatase, HVH2, which selectively dephosphorylates the mitogen-activated protein kinase. J Biol Chem. 1995; 270: 7197-7203. PMID: 7535768
    • (1995) J Biol Chem. , vol.270 , pp. 7197-7203
    • Guan, K.L.1    Butch, E.2
  • 5
    • 0029918680 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation
    • 8626452
    • Chu Y, Solski PA, Khosravi-Far R, Der CJ, Kelly K. The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation. J Biol Chem. 1996; 271: 6497-6501. PMID: 8626452
    • (1996) J Biol Chem. , vol.271 , pp. 6497-6501
    • Chu, Y.1    Solski, P.A.2    Khosravi-Far, R.3    Der, C.J.4    Kelly, K.5
  • 6
    • 13844270779 scopus 로고    scopus 로고
    • Disruption of two putative nuclear localization sequences is required for cytosolic localization of mitogen-activated protein kinase phosphatase-2
    • 15722195
    • Sloss CM, Cadalbert L, Finn SG, Fuller SJ, Plevin R. Disruption of two putative nuclear localization sequences is required for cytosolic localization of mitogen-activated protein kinase phosphatase-2. Cell Signal. 2005; 17: 709-716. PMID: 15722195
    • (2005) Cell Signal. , vol.17 , pp. 709-716
    • Sloss, C.M.1    Cadalbert, L.2    Finn, S.G.3    Fuller, S.J.4    Plevin, R.5
  • 7
    • 34447512474 scopus 로고    scopus 로고
    • HoxA10 activates transcription of the gene encoding mitogen-activated protein kinase phosphatase 2 (Mkp2) in myeloid cells
    • 17430893
    • Wang H, Lu Y, Huang W, Papoutsakis ET, Fuhrken P, Eklund EA. HoxA10 activates transcription of the gene encoding mitogen-activated protein kinase phosphatase 2 (Mkp2) in myeloid cells. J Biol Chem. 2007; 282: 16164-16176. PMID: 17430893
    • (2007) J Biol Chem. , vol.282 , pp. 16164-16176
    • Wang, H.1    Lu, Y.2    Huang, W.3    Papoutsakis, E.T.4    Fuhrken, P.5    Eklund, E.A.6
  • 8
    • 33745685904 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase phosphatase 2: A novel transcription target of p53 in apoptosis
    • 16778175
    • Shen WH, Wang J, Wu J, Zhurkin VB, Yin Y. Mitogen-activated protein kinase phosphatase 2: a novel transcription target of p53 in apoptosis. Cancer Res. 2006; 66: 6033-6039. PMID: 16778175
    • (2006) Cancer Res. , vol.66 , pp. 6033-6039
    • Shen, W.H.1    Wang, J.2    Wu, J.3    Zhurkin, V.B.4    Yin, Y.5
  • 9
    • 0142011160 scopus 로고    scopus 로고
    • Metabolic stabilization of MAP kinase phosphatase-2 in senescence of human fibroblasts
    • 14567979
    • Torres C, Francis MK, Lorenzini A, Tresini M, Cristofalo VJ. Metabolic stabilization of MAP kinase phosphatase-2 in senescence of human fibroblasts. Exp Cell Res. 2003; 290: 195-206. PMID: 14567979
    • (2003) Exp Cell Res. , vol.290 , pp. 195-206
    • Torres, C.1    Francis, M.K.2    Lorenzini, A.3    Tresini, M.4    Cristofalo, V.J.5
  • 10
    • 34249989400 scopus 로고    scopus 로고
    • Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres
    • 17491589
    • Meier A, Fiegler H, Munoz P, Ellis P, Rigler D, Langford C, et al. Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres. Embo J. 2007; 26: 2707-2718. PMID: 17491589
    • (2007) Embo J. , vol.26 , pp. 2707-2718
    • Meier, A.1    Fiegler, H.2    Munoz, P.3    Ellis, P.4    Rigler, D.5    Langford, C.6
  • 11
    • 35349022491 scopus 로고    scopus 로고
    • Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress
    • 17681939
    • Teng CH, Huang WN, Meng TC. Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress. J Biol Chem. 2007; 282: 28395-28407. PMID: 17681939
    • (2007) J Biol Chem. , vol.282 , pp. 28395-28407
    • Teng, C.H.1    Huang, W.N.2    Meng, T.C.3
  • 12
    • 53249137795 scopus 로고    scopus 로고
    • TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2
    • 18704116
    • Ramesh S, Qi XJ, Wildey GM, Robinson J, Molkentin J, Letterio J, et al. TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2. EMBO Rep. 2008; 9: 990-997. doi: 10.1038/embor.2008.158 PMID: 18704116
    • (2008) EMBO Rep. , vol.9 , pp. 990-997
    • Ramesh, S.1    Qi, X.J.2    Wildey, G.M.3    Robinson, J.4    Molkentin, J.5    Letterio, J.6
  • 13
    • 77952725007 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase phosphatase 2 regulates the inflammatory response in sepsis
    • 20351138
    • Cornell TT, Rodenhouse P, Cai Q, Sun L, Shanley TP. Mitogen-activated protein kinase phosphatase 2 regulates the inflammatory response in sepsis. Infect Immun. 2010; 78: 2868-2876. doi: 10.1128/IAI. 00018-10 PMID: 20351138
    • (2010) Infect Immun. , vol.78 , pp. 2868-2876
    • Cornell, T.T.1    Rodenhouse, P.2    Cai, Q.3    Sun, L.4    Shanley, T.P.5
  • 14
    • 79251515475 scopus 로고    scopus 로고
    • MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana
    • 21085614
    • Al-Mutairi MS, Cadalbert LC, McGachy HA, Shweash M, Schroeder J, Kurnik M, et al. MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana. PLoS Pathog. 2010; 6: e1001192. doi: 10.1371/journal.ppat.1001192 PMID: 21085614
    • (2010) PLoS Pathog. , vol.6
    • Al-Mutairi, M.S.1    Cadalbert, L.C.2    McGachy, H.A.3    Shweash, M.4    Schroeder, J.5    Kurnik, M.6
  • 15
    • 84862933832 scopus 로고    scopus 로고
    • DUSP4 deficiency enhances CD25 expression and CD4+ T-cell proliferation without impeding T-cell development
    • 22101742
    • Huang CY, Lin YC, Hsiao WY, Liao FH, Huang PY, Tan TH. DUSP4 deficiency enhances CD25 expression and CD4+ T-cell proliferation without impeding T-cell development. Eur J Immunol. 2012; 42: 476-488. doi: 10.1002/eji.201041295 PMID: 22101742
    • (2012) Eur J Immunol. , vol.42 , pp. 476-488
    • Huang, C.Y.1    Lin, Y.C.2    Hsiao, W.Y.3    Liao, F.H.4    Huang, P.Y.5    Tan, T.H.6
  • 16
    • 84859574715 scopus 로고    scopus 로고
    • Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age
    • 22434910
    • Yu M, Li G, Lee WW, Yuan M, Cui D, Weyand CM, et al. Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age. Proc Natl Acad Sci U S A. 2012; 109: E879-888. doi: 10.1073/pnas.1109797109 PMID: 22434910
    • (2012) Proc Natl Acad Sci U S A. , vol.109 , pp. E879-888
    • Yu, M.1    Li, G.2    Lee, W.W.3    Yuan, M.4    Cui, D.5    Weyand, C.M.6
  • 17
    • 33947720523 scopus 로고    scopus 로고
    • Development in motion: Helper T cells at work
    • 17418783
    • Reiner SL. Development in motion: helper T cells at work. Cell. 2007; 129: 33-36. PMID: 17418783
    • (2007) Cell. , vol.129 , pp. 33-36
    • Reiner, S.L.1
  • 18
    • 77955890953 scopus 로고    scopus 로고
    • Interleukin-2 receptor signaling: At the interface between tolerance and immunity
    • 20732639
    • Malek TR, Castro I. Interleukin-2 receptor signaling: at the interface between tolerance and immunity. Immunity. 2010; 33: 153-165. doi: 10.1016/j.immuni.2010.08.004 PMID: 20732639
    • (2010) Immunity. , vol.33 , pp. 153-165
    • Malek, T.R.1    Castro, I.2
  • 19
    • 4644369302 scopus 로고    scopus 로고
    • Interleukin-2 is essential for CD4+CD25+ regulatory T cell function
    • 15307180
    • de la Rosa M, Rutz S, Dorninger H, Scheffold A. Interleukin-2 is essential for CD4+CD25+ regulatory T cell function. Eur J Immunol. 2004; 34: 2480-2488. PMID: 15307180
    • (2004) Eur J Immunol. , vol.34 , pp. 2480-2488
    • De La Rosa, M.1    Rutz, S.2    Dorninger, H.3    Scheffold, A.4
  • 20
    • 33947162110 scopus 로고    scopus 로고
    • Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
    • 17363300
    • Laurence A, Tato CM, Davidson TS, Kanno Y, Chen Z, Yao Z, et al. Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity. 2007; 26: 371-381. PMID: 17363300
    • (2007) Immunity. , vol.26 , pp. 371-381
    • Laurence, A.1    Tato, C.M.2    Davidson, T.S.3    Kanno, Y.4    Chen, Z.5    Yao, Z.6
  • 21
    • 78649752513 scopus 로고    scopus 로고
    • Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis
    • 21209700
    • Domingues HS, Mues M, Lassmann H, Wekerle H, Krishnamoorthy G. Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis. PLoS One. 2010; 5: e15531. doi: 10.1371/journal.pone.0015531 PMID: 21209700
    • (2010) PLoS One. , vol.5
    • Domingues, H.S.1    Mues, M.2    Lassmann, H.3    Wekerle, H.4    Krishnamoorthy, G.5
  • 22
    • 56149125346 scopus 로고    scopus 로고
    • Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis
    • 18768826
    • O'Connor RA, Prendergast CT, Sabatos CA, Lau CW, Leech MD, Wraith DC, et al. Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis. J Immunol. 2008; 181: 3750-3754. PMID: 18768826
    • (2008) J Immunol. , vol.181 , pp. 3750-3754
    • O'Connor, R.A.1    Prendergast, C.T.2    Sabatos, C.A.3    Lau, C.W.4    Leech, M.D.5    Wraith, D.C.6
  • 23
    • 0036838536 scopus 로고    scopus 로고
    • Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
    • 12391178
    • Kohm AP, Carpentier PA, Anger HA, Miller SD. Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J Immunol. 2002; 169: 4712-4716. PMID: 12391178
    • (2002) J Immunol. , vol.169 , pp. 4712-4716
    • Kohm, A.P.1    Carpentier, P.A.2    Anger, H.A.3    Miller, S.D.4
  • 24
    • 33750219508 scopus 로고    scopus 로고
    • Both integrated and differential regulation of components of the IL-2/IL-2 receptor system
    • 16911870
    • Kim HP, Imbert J, Leonard WJ. Both integrated and differential regulation of components of the IL-2/IL-2 receptor system. Cytokine Growth Factor Rev. 2006; 17: 349-366. PMID: 16911870
    • (2006) Cytokine Growth Factor Rev. , vol.17 , pp. 349-366
    • Kim, H.P.1    Imbert, J.2    Leonard, W.J.3
  • 25
    • 0032577678 scopus 로고    scopus 로고
    • Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
    • 9630226
    • Chen X, Vinkemeier U, Zhao Y, Jeruzalmi D, Darnell JE Jr, Kuriyan J. Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell. 1998; 93: 827-839. PMID: 9630226
    • (1998) Cell. , vol.93 , pp. 827-839
    • Chen, X.1    Vinkemeier, U.2    Zhao, Y.3    Jeruzalmi, D.4    Darnell, J.E.5    Kuriyan, J.6
  • 26
    • 84902589832 scopus 로고    scopus 로고
    • STATs get their move on
    • 24470978
    • Reich NC. STATs get their move on. JAKSTAT. 2013; 2: e27080. doi: 10.4161/jkst.27080 PMID: 24470978
    • (2013) JAKSTAT , vol.2
    • Reich, N.C.1
  • 27
    • 0032921172 scopus 로고    scopus 로고
    • The STAT family of proteins in cytokine signaling
    • 10354707
    • Shuai K. The STAT family of proteins in cytokine signaling. Prog Biophys Mol Biol. 1999; 71: 405-422. PMID: 10354707
    • (1999) Prog Biophys Mol Biol. , vol.71 , pp. 405-422
    • Shuai, K.1
  • 28
    • 34547108380 scopus 로고    scopus 로고
    • JAK-STAT signaling: From interferons to cytokines
    • 17502367
    • Schindler C, Levy DE, Decker T. JAK-STAT signaling: from interferons to cytokines. J Biol Chem. 2007; 282: 20059-20063. PMID: 17502367
    • (2007) J Biol Chem. , vol.282 , pp. 20059-20063
    • Schindler, C.1    Levy, D.E.2    Decker, T.3
  • 29
    • 52949151882 scopus 로고    scopus 로고
    • New insights into the roles of Stat5a/b and Stat3 in T cell development and differentiation
    • 18708155
    • Wei L, Laurence A, O'Shea JJ. New insights into the roles of Stat5a/b and Stat3 in T cell development and differentiation. Semin Cell Dev Biol. 2008; 19: 394-400. doi: 10.1016/j.semcdb.2008.07.011 PMID: 18708155
    • (2008) Semin Cell Dev Biol. , vol.19 , pp. 394-400
    • Wei, L.1    Laurence, A.2    O'Shea, J.J.3
  • 30
    • 33845935950 scopus 로고    scopus 로고
    • IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells
    • 17182565
    • Burchill MA, Yang J, Vogtenhuber C, Blazar BR, Farrar MA. IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells. J Immunol. 2007; 178: 280-290. PMID: 17182565
    • (2007) J Immunol. , vol.178 , pp. 280-290
    • Burchill, M.A.1    Yang, J.2    Vogtenhuber, C.3    Blazar, B.R.4    Farrar, M.A.5
  • 31
    • 79958021546 scopus 로고    scopus 로고
    • IL-2 controls the stability of Foxp3 expression in TGF-beta-induced Foxp3+ T cells in vivo
    • 21525380
    • Chen Q, Kim YC, Laurence A, Punkosdy GA, Shevach EM. IL-2 controls the stability of Foxp3 expression in TGF-beta-induced Foxp3+ T cells in vivo. J Immunol. 2011; 186: 6329-6337. doi: 10.4049/jimmunol.1100061 PMID: 21525380
    • (2011) J Immunol. , vol.186 , pp. 6329-6337
    • Chen, Q.1    Kim, Y.C.2    Laurence, A.3    Punkosdy, G.A.4    Shevach, E.M.5
  • 32
    • 0027993605 scopus 로고
    • Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription
    • 7925280
    • Gouilleux F, Wakao H, Mundt M, Groner B. Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription. EMBO J. 1994; 13: 4361-4369. PMID: 7925280
    • (1994) EMBO J. , vol.13 , pp. 4361-4369
    • Gouilleux, F.1    Wakao, H.2    Mundt, M.3    Groner, B.4
  • 33
    • 0035950441 scopus 로고    scopus 로고
    • Role of serine phosphorylation of Stat5a in prolactin-stimulated beta-casein gene expression
    • 11604235
    • Yamashita H, Nevalainen MT, Xu J, LeBaron MJ, Wagner KU, Erwin RA, et al. Role of serine phosphorylation of Stat5a in prolactin-stimulated beta-casein gene expression. Mol Cell Endocrinol. 2001; 183: 151-163. PMID: 11604235
    • (2001) Mol Cell Endocrinol. , vol.183 , pp. 151-163
    • Yamashita, H.1    Nevalainen, M.T.2    Xu, J.3    LeBaron, M.J.4    Wagner, K.U.5    Erwin, R.A.6
  • 34
    • 0029936611 scopus 로고    scopus 로고
    • Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway
    • 8617237
    • Beadling C, Ng J, Babbage JW, Cantrell DA. Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway. EMBO J. 1996; 15: 1902-1913. PMID: 8617237
    • (1996) EMBO J. , vol.15 , pp. 1902-1913
    • Beadling, C.1    Ng, J.2    Babbage, J.W.3    Cantrell, D.A.4
  • 36
    • 67651152910 scopus 로고    scopus 로고
    • Tumor suppression by phospholipase Cbeta3 via SHP-1-mediated dephosphorylation of Stat5
    • 19647226
    • Xiao W, Hong H, Kawakami Y, Kato Y, Wu D, Yasudo H, et al. Tumor suppression by phospholipase Cbeta3 via SHP-1-mediated dephosphorylation of Stat5. Cancer Cell. 2009; 16: 161-171. doi: 10.1016/j. ccr.2009.05.018 PMID: 19647226
    • (2009) Cancer Cell. , vol.16 , pp. 161-171
    • Xiao, W.1    Hong, H.2    Kawakami, Y.3    Kato, Y.4    Wu, D.5    Yasudo, H.6
  • 37
    • 35748980594 scopus 로고    scopus 로고
    • Cutting edge: Selective tyrosine dephosphorylation of interferon-activated nuclear STAT5 by the VHR phosphatase
    • 17785772
    • Hoyt R, Zhu W, Cerignoli F, Alonso A, Mustelin T, David M. Cutting edge: selective tyrosine dephosphorylation of interferon-activated nuclear STAT5 by the VHR phosphatase. J Immunol. 2007; 179: 3402-3406. PMID: 17785772
    • (2007) J Immunol. , vol.179 , pp. 3402-3406
    • Hoyt, R.1    Zhu, W.2    Cerignoli, F.3    Alonso, A.4    Mustelin, T.5    David, M.6
  • 38
    • 0034671546 scopus 로고    scopus 로고
    • A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b
    • 10993888
    • Aoki N, Matsuda T. A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b. J Biol Chem. 2000; 275: 39718-39726. PMID: 10993888
    • (2000) J Biol Chem. , vol.275 , pp. 39718-39726
    • Aoki, N.1    Matsuda, T.2
  • 39
    • 38949155134 scopus 로고    scopus 로고
    • Constitutive nuclear import of latent and activated STAT5a by its coiled coil domain
    • 17846080
    • Iyer J, Reich NC. Constitutive nuclear import of latent and activated STAT5a by its coiled coil domain. FASEB J. 2008; 22: 391-400. PMID: 17846080
    • (2008) FASEB J. , vol.22 , pp. 391-400
    • Iyer, J.1    Reich, N.C.2
  • 40
    • 84883337867 scopus 로고    scopus 로고
    • Dynamic trafficking of STAT5 depends on an unconventional nuclear localization signal
    • 23704351
    • Shin HY, Reich NC. Dynamic trafficking of STAT5 depends on an unconventional nuclear localization signal. J Cell Sci. 2013; 126: 3333-3343. doi: 10.1242/jcs.123042 PMID: 23704351
    • (2013) J Cell Sci. , vol.126 , pp. 3333-3343
    • Shin, H.Y.1    Reich, N.C.2
  • 41
    • 0034142208 scopus 로고    scopus 로고
    • A small amphipathic alphahelical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5
    • 10654938
    • Wang D, Moriggl R, Stravopodis D, Carpino N, Marine JC, Teglund S, et al. A small amphipathic alphahelical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5. EMBO J. 2000; 19: 392-399. PMID: 10654938
    • (2000) EMBO J. , vol.19 , pp. 392-399
    • Wang, D.1    Moriggl, R.2    Stravopodis, D.3    Carpino, N.4    Marine, J.C.5    Teglund, S.6
  • 42
    • 33846851777 scopus 로고    scopus 로고
    • Degradation of STAT5 proteins in 3T3-L1 adipocytes is induced by TNF-{alpha} and cycloheximide in a manner independent of STAT5A activation
    • 16985255
    • Floyd ZE, Segura BM, He F, Stephens JM. Degradation of STAT5 proteins in 3T3-L1 adipocytes is induced by TNF-{alpha} and cycloheximide in a manner independent of STAT5A activation. Am J Physiol Endocrinol Metab. 2007; 292: E461-468. PMID: 16985255
    • (2007) Am J Physiol Endocrinol Metab. , vol.292 , pp. E461-468
    • Floyd, Z.E.1    Segura, B.M.2    He, F.3    Stephens, J.M.4
  • 43
  • 45
    • 42949146948 scopus 로고    scopus 로고
    • Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors
    • 18425137
    • Ai HW, Hazelwood KL, Davidson MW, Campbell RE. Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors. Nat Methods. 2008; 5: 401-403. doi: 10.1038/nmeth.1207 PMID: 18425137
    • (2008) Nat Methods. , vol.5 , pp. 401-403
    • Ai, H.W.1    Hazelwood, K.L.2    Davidson, M.W.3    Campbell, R.E.4
  • 46
    • 0034038990 scopus 로고    scopus 로고
    • Stimulation of endogenous GH and interleukin-6 receptors selectively activates different Jaks and Stats, with a Stat5 specific synergistic effect of dexamethasone
    • 10810294
    • von Laue S, Finidori J, Maamra M, Shen XY, Justice S, Dobson PR, et al. Stimulation of endogenous GH and interleukin-6 receptors selectively activates different Jaks and Stats, with a Stat5 specific synergistic effect of dexamethasone. J Endocrinol. 2000; 165: 301-311. PMID: 10810294
    • (2000) J Endocrinol. , vol.165 , pp. 301-311
    • Von Laue, S.1    Finidori, J.2    Maamra, M.3    Shen, X.Y.4    Justice, S.5    Dobson, P.R.6
  • 47
    • 0029909494 scopus 로고    scopus 로고
    • Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons
    • 8943349
    • Meinke A, Barahmand-Pour F, Wohrl S, Stoiber D, Decker T. Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons. Mol Cell Biol. 1996; 16: 6937-6944. PMID: 8943349
    • (1996) Mol Cell Biol. , vol.16 , pp. 6937-6944
    • Meinke, A.1    Barahmand-Pour, F.2    Wohrl, S.3    Stoiber, D.4    Decker, T.5
  • 49
    • 84859416933 scopus 로고    scopus 로고
    • Regulatory T cells: Mechanisms of differentiation and function
    • 22224781
    • Josefowicz SZ, Lu LF, Rudensky AY. Regulatory T cells: mechanisms of differentiation and function. Annu Rev Immunol. 2012; 30: 531-564. doi: 10.1146/annurev.immunol.25.022106.141623 PMID: 22224781
    • (2012) Annu Rev Immunol. , vol.30 , pp. 531-564
    • Josefowicz, S.Z.1    Lu, L.F.2    Rudensky, A.Y.3
  • 51
    • 34247564147 scopus 로고    scopus 로고
    • Nonredundant roles for Stat5a/b in directly regulating Foxp3
    • 17227828
    • Yao Z, Kanno Y, Kerenyi M, Stephens G, Durant L, Watford WT, et al. Nonredundant roles for Stat5a/b in directly regulating Foxp3. Blood. 2007; 109: 4368-4375. PMID: 17227828
    • (2007) Blood. , vol.109 , pp. 4368-4375
    • Yao, Z.1    Kanno, Y.2    Kerenyi, M.3    Stephens, G.4    Durant, L.5    Watford, W.T.6
  • 52
    • 0029416997 scopus 로고
    • Isolation and characterisation of a uniquely regulated threonine, tyrosine phosphatase (TYP 1) which inactivates ERK2 and p54jnk
    • 8545112
    • King AG, Ozanne BW, Smythe C, Ashworth A. Isolation and characterisation of a uniquely regulated threonine, tyrosine phosphatase (TYP 1) which inactivates ERK2 and p54jnk. Oncogene. 1995; 11: 2553-2563. PMID: 8545112
    • (1995) Oncogene. , vol.11 , pp. 2553-2563
    • King, A.G.1    Ozanne, B.W.2    Smythe, C.3    Ashworth, A.4
  • 53
    • 0036493771 scopus 로고    scopus 로고
    • Calpain is a signal transducer and activator of transcription (STAT) 3 and STAT5 protease
    • 11861304
    • Oda A, Wakao H, Fujita H. Calpain is a signal transducer and activator of transcription (STAT) 3 and STAT5 protease. Blood. 2002; 99: 1850-1852. PMID: 11861304
    • (2002) Blood. , vol.99 , pp. 1850-1852
    • Oda, A.1    Wakao, H.2    Fujita, H.3
  • 55
    • 84874425321 scopus 로고    scopus 로고
    • Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy
    • 22993413
    • Auger-Messier M, Accornero F, Goonasekera SA, Bueno OF, Lorenz JN, van Berlo JH, et al. Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy. Circ Res. 2013; 112: 48-56. doi: 10.1161/CIRCRESAHA.112.272963 PMID: 22993413
    • (2013) Circ Res. , vol.112 , pp. 48-56
    • Auger-Messier, M.1    Accornero, F.2    Goonasekera, S.A.3    Bueno, O.F.4    Lorenz, J.N.5    Van Berlo, J.H.6
  • 56
    • 47749110211 scopus 로고    scopus 로고
    • T-cell development and function are modulated by dual specificity phosphatase DUSP5
    • 18430737
    • Kovanen PE, Bernard J, Al-Shami A, Liu C, Bollenbacher-Reilley J, Young L, et al. T-cell development and function are modulated by dual specificity phosphatase DUSP5. J Biol Chem. 2008; 283: 17362-17369. doi: 10.1074/jbc.M709887200 PMID: 18430737
    • (2008) J Biol Chem. , vol.283 , pp. 17362-17369
    • Kovanen, P.E.1    Bernard, J.2    Al-Shami, A.3    Liu, C.4    Bollenbacher-Reilley, J.5    Young, L.6
  • 57
    • 36049034347 scopus 로고    scopus 로고
    • MAP kinase phosphatase activity sets the threshold for thymocyte positive selection
    • 17901205
    • Bettini ML, Kersh GJ. MAP kinase phosphatase activity sets the threshold for thymocyte positive selection. Proc Natl Acad Sci U S A. 2007; 104: 16257-16262. PMID: 17901205
    • (2007) Proc Natl Acad Sci U S A. , vol.104 , pp. 16257-16262
    • Bettini, M.L.1    Kersh, G.J.2
  • 58
    • 84925581289 scopus 로고    scopus 로고
    • Dual-specificity phosphatase 5 attenuates autoimmune arthritis in mice via reciprocal regulation of the Th17/Treg cell balance and inhibition of osteoclastogenesis
    • 25047518
    • Moon SJ, Lim MA, Park JS, Byun JK, Kim SM, Park MK, et al. Dual-specificity phosphatase 5 attenuates autoimmune arthritis in mice via reciprocal regulation of the Th17/Treg cell balance and inhibition of osteoclastogenesis. Arthritis Rheumatol. 2014; 66: 3083-3095. doi: 10.1002/art.38787 PMID: 25047518
    • (2014) Arthritis Rheumatol. , vol.66 , pp. 3083-3095
    • Moon, S.J.1    Lim, M.A.2    Park, J.S.3    Byun, J.K.4    Kim, S.M.5    Park, M.K.6
  • 59
    • 33646192473 scopus 로고    scopus 로고
    • Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1
    • 16474395
    • Jeffrey KL, Brummer T, Rolph MS, Liu SM, Callejas NA, Grumont RJ, et al. Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1. Nat Immunol. 2006; 7: 274-283. PMID: 16474395
    • (2006) Nat Immunol. , vol.7 , pp. 274-283
    • Jeffrey, K.L.1    Brummer, T.2    Rolph, M.S.3    Liu, S.M.4    Callejas, N.A.5    Grumont, R.J.6
  • 60
    • 4043076210 scopus 로고    scopus 로고
    • Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5
    • 15306813
    • Zhang Y, Blattman JN, Kennedy NJ, Duong J, Nguyen T, Wang Y, et al. Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5. Nature. 2004; 430: 793-797. PMID: 15306813
    • (2004) Nature. , vol.430 , pp. 793-797
    • Zhang, Y.1    Blattman, J.N.2    Kennedy, N.J.3    Duong, J.4    Nguyen, T.5    Wang, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.