DUSP4 deficiency enhances CD25 expression and CD4 + T-cell proliferation without impeding T-cell development

European Journal of Immunology

Volumn 42, Issue 2, 2012, Pages 476-488

  Huang, Ching Yu ^a   Lin, Yu Chun ^a   Hsiao, Wan Yi ^a   Liao, Fang Hsuean ^a   Huang, Pau Yi ^a   Tan, Tse Hua ^a,b  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Cytokines; DUSP4 MKP2; Immune regulation; Knockout mice; Signal transduction

Indexed keywords

CHEMOKINE RECEPTOR CXCR5; DUAL SPECIFICITY PHOSPHATASE; DUAL SPECIFICITY PHOSPHATASE 4; I KAPPA B KINASE BETA; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 2 RECEPTOR ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; STAT5 PROTEIN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIGEN RECOGNITION; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL MATURATION; CELL POLARITY; CELL PROLIFERATION; CELL SELECTION; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNIZATION; IN VITRO STUDY; LYMPH NODE CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TH1 CELL; TH2 CELL; THYMOCYTE;

ANIMALS; ANTIGENS, CD4; ANTIGENS, CD8; CELL DIFFERENTIATION; CELL GROWTH PROCESSES; CELLS, CULTURED; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE ACTIVATION; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASES; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; T-LYMPHOCYTE SUBSETS; THYMUS GLAND;

EID: 84862933832     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201041295     Document Type: Article

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