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Volumn 22, Issue 2, 2008, Pages 391-400

Constitutive nuclear import of latent and activated STAT5a by its coiled coil domain

Author keywords

Live cell imaging; Nuclear trafficking; Transcription factor; Tyrosine phosphorylation

Indexed keywords

STAT5A PROTEIN; TYROSINE;

EID: 38949155134     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-8965com     Document Type: Article
Times cited : (38)

References (52)
  • 1
    • 0036731485 scopus 로고    scopus 로고
    • Stats: Transcriptional control and biological impact
    • Levy, D. E., and Darnell, J. E., Jr. (2002) Stats: transcriptional control and biological impact. Nat. Rev. Mol. Cell Biol. 3, 651-662
    • (2002) Nat. Rev. Mol. Cell Biol , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell Jr., J.E.2
  • 2
    • 0034046605 scopus 로고    scopus 로고
    • STAT family of transcription factors in cytokine-mediated biological responses
    • Takeda, K., and Akira, S. (2000) STAT family of transcription factors in cytokine-mediated biological responses. Cytokine Growth Factor Rev. 11, 199-207
    • (2000) Cytokine Growth Factor Rev , vol.11 , pp. 199-207
    • Takeda, K.1    Akira, S.2
  • 3
    • 33748450379 scopus 로고    scopus 로고
    • Complex modulation of cell type-specific signaling in response to type I interferons
    • Van Boxel-Dezaire, A. H., Rani, M. R., and Stark, G. R. (2006) Complex modulation of cell type-specific signaling in response to type I interferons. Immunity 25, 361-372
    • (2006) Immunity , vol.25 , pp. 361-372
    • Van Boxel-Dezaire, A.H.1    Rani, M.R.2    Stark, G.R.3
  • 4
    • 33746570647 scopus 로고    scopus 로고
    • Tracking STAT nuclear traffic
    • Reich, N. C., and Liu, L. (2006) Tracking STAT nuclear traffic. Nature Rev. 6, 602-612
    • (2006) Nature Rev , vol.6 , pp. 602-612
    • Reich, N.C.1    Liu, L.2
  • 5
    • 30444458235 scopus 로고    scopus 로고
    • Stats: Multifaceted regulators of transcription
    • Brierley, M. M., and Fish, E. N. (2005) Stats: multifaceted regulators of transcription. J. Interferon Cytokine Res. 25, 733-744
    • (2005) J. Interferon Cytokine Res , vol.25 , pp. 733-744
    • Brierley, M.M.1    Fish, E.N.2
  • 6
    • 4444268818 scopus 로고    scopus 로고
    • Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation
    • Cui, Y., Riedlinger, G., Miyoshi, K., Tang, W., Li, C., Deng, C. X., Robinson, G. W., and Hennighausen, L. (2004) Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation. Mol. Cell. Biol. 24, 8037-8047
    • (2004) Mol. Cell. Biol , vol.24 , pp. 8037-8047
    • Cui, Y.1    Riedlinger, G.2    Miyoshi, K.3    Tang, W.4    Li, C.5    Deng, C.X.6    Robinson, G.W.7    Hennighausen, L.8
  • 8
    • 4544371118 scopus 로고    scopus 로고
    • Constitutive activation of STAT5A promotes human hematopoietic stem cell self-renewal and erythroid differentiation
    • Schuringa, J. J., Chung, K. Y., Morrone, G., and Moore, M. A. (2004) Constitutive activation of STAT5A promotes human hematopoietic stem cell self-renewal and erythroid differentiation. J. Exp. Med. 200, 623-635
    • (2004) J. Exp. Med , vol.200 , pp. 623-635
    • Schuringa, J.J.1    Chung, K.Y.2    Morrone, G.3    Moore, M.A.4
  • 10
    • 33344462686 scopus 로고    scopus 로고
    • The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development
    • Clarkson, R. W., Boland, M. P., Kritikou, E. A., Lee, J. M., Freeman, T. C., Tiffen, P. G., and Watson, C. J. (2006) The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development. Mol. Endocrinol. 20, 675-685
    • (2006) Mol. Endocrinol , vol.20 , pp. 675-685
    • Clarkson, R.W.1    Boland, M.P.2    Kritikou, E.A.3    Lee, J.M.4    Freeman, T.C.5    Tiffen, P.G.6    Watson, C.J.7
  • 11
    • 0034469415 scopus 로고    scopus 로고
    • Linear and cooperative signaling: Roles for Stat proteins in the regulation of cell survival and apoptosis in the mammary epithelium
    • Groner, B., and Hennighausen, L. (2000) Linear and cooperative signaling: roles for Stat proteins in the regulation of cell survival and apoptosis in the mammary epithelium. Breast Cancer Res. 2, 149-153
    • (2000) Breast Cancer Res , vol.2 , pp. 149-153
    • Groner, B.1    Hennighausen, L.2
  • 12
    • 0032831735 scopus 로고    scopus 로고
    • Stat5a and Stat5b: Fraternal twins of signal transduction and transcriptional activation
    • Grimley, P. M., Dong, F., and Rui, H. (1999) Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation. Cytokine Growth Factor Rev. 10, 131-157
    • (1999) Cytokine Growth Factor Rev , vol.10 , pp. 131-157
    • Grimley, P.M.1    Dong, F.2    Rui, H.3
  • 13
    • 0031919849 scopus 로고    scopus 로고
    • Jaks and STATs: Biological implications
    • Leonard, W. J., and O'Shea, J. J. (1998) Jaks and STATs: biological implications. Annu. Rev. Immunol. 16, 293-322
    • (1998) Annu. Rev. Immunol , vol.16 , pp. 293-322
    • Leonard, W.J.1    O'Shea, J.J.2
  • 14
    • 33745057158 scopus 로고    scopus 로고
    • STAT5 signaling is required for the efficient induction and maintenance of CML in mice
    • Ye, D., Wolff, N., Li, L., Zhang, S., and Ilaria, R. L., Jr. (2006) STAT5 signaling is required for the efficient induction and maintenance of CML in mice. Blood 107, 4917-4925
    • (2006) Blood , vol.107 , pp. 4917-4925
    • Ye, D.1    Wolff, N.2    Li, L.3    Zhang, S.4    Ilaria Jr., R.L.5
  • 16
    • 0035912097 scopus 로고    scopus 로고
    • Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway
    • Santos, S. C., Lacronique, V., Bouchaert, I., Monni, R., Bernard, O., Gisselbrecht, S., and Gouilleux, F. (2001) Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway. Oncogene 20, 2080-2090
    • (2001) Oncogene , vol.20 , pp. 2080-2090
    • Santos, S.C.1    Lacronique, V.2    Bouchaert, I.3    Monni, R.4    Bernard, O.5    Gisselbrecht, S.6    Gouilleux, F.7
  • 17
    • 0036098153 scopus 로고    scopus 로고
    • STAT5 promotes multilineage hematolymphoid development in vivo through effects on early hematopoietic progenitor cells
    • Snow, J. W., Abraham, N., Ma, M. C., Abbey, N. W., Herndier, B., and Goldsmith, M. A. (2002) STAT5 promotes multilineage hematolymphoid development in vivo through effects on early hematopoietic progenitor cells. Blood 99, 95-101
    • (2002) Blood , vol.99 , pp. 95-101
    • Snow, J.W.1    Abraham, N.2    Ma, M.C.3    Abbey, N.W.4    Herndier, B.5    Goldsmith, M.A.6
  • 18
    • 21344435775 scopus 로고    scopus 로고
    • Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer
    • Haura, E. B., Turkson, J., and Jove, R. (2005) Mechanisms of disease: insights into the emerging role of signal transducers and activators of transcription in cancer. Nat. Clin. Pract. Oncol. 2, 315-324
    • (2005) Nat. Clin. Pract. Oncol , vol.2 , pp. 315-324
    • Haura, E.B.1    Turkson, J.2    Jove, R.3
  • 19
    • 33745827054 scopus 로고    scopus 로고
    • A role for STAT5A/B in protection of peripheral T-lymphocytes from postactivation apoptosis: Insights from gene expression profiling
    • Gatzka, M., Piekorz, R., Moriggl, R., Rawlings, J., and Ihle, J. N. (2006) A role for STAT5A/B in protection of peripheral T-lymphocytes from postactivation apoptosis: insights from gene expression profiling. Cytokine 34, 143-154
    • (2006) Cytokine , vol.34 , pp. 143-154
    • Gatzka, M.1    Piekorz, R.2    Moriggl, R.3    Rawlings, J.4    Ihle, J.N.5
  • 20
    • 0037852129 scopus 로고    scopus 로고
    • Stimulation of primary human endothelial cell proliferation by IFN
    • Gomez, D., and Reich, N. C. (2003) Stimulation of primary human endothelial cell proliferation by IFN. J. Immunol. 170, 5373-5381
    • (2003) J. Immunol , vol.170 , pp. 5373-5381
    • Gomez, D.1    Reich, N.C.2
  • 21
    • 0033279841 scopus 로고    scopus 로고
    • Transport between the cell nucleus and the cytoplasm
    • Gorlich, D., and Kutay, U. (1999) Transport between the cell nucleus and the cytoplasm. Annu. Rev. Cell Dev. Biol. 15, 607-660
    • (1999) Annu. Rev. Cell Dev. Biol , vol.15 , pp. 607-660
    • Gorlich, D.1    Kutay, U.2
  • 22
    • 33745508014 scopus 로고    scopus 로고
    • Introduction to nucleocytoplasmic transport: Molecules and mechanisms
    • Peters, R. (2006) Introduction to nucleocytoplasmic transport: molecules and mechanisms. Methods Mol. Biol. 322, 235-258
    • (2006) Methods Mol. Biol , vol.322 , pp. 235-258
    • Peters, R.1
  • 23
    • 0038701027 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: Navigating the channel
    • Bednenko, J., Cingolani, G., and Gerace, L. (2003) Nucleocytoplasmic transport: navigating the channel. Traffic 4, 127-135
    • (2003) Traffic , vol.4 , pp. 127-135
    • Bednenko, J.1    Cingolani, G.2    Gerace, L.3
  • 24
    • 14544299215 scopus 로고    scopus 로고
    • Mechanisms of receptor-mediated nuclear import and nuclear export
    • Pemberton, L. F., and Paschal, B. M. (2005) Mechanisms of receptor-mediated nuclear import and nuclear export. Traffic 6, 187-198
    • (2005) Traffic , vol.6 , pp. 187-198
    • Pemberton, L.F.1    Paschal, B.M.2
  • 26
    • 0032577678 scopus 로고    scopus 로고
    • Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
    • Chen, X., Vinkemeier, U., Zhao, Y., Jeruzalmi, D., Darnell, J. E., Jr., and Kuriyan, J. (1998) Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell 93, 827-839
    • (1998) Cell , vol.93 , pp. 827-839
    • Chen, X.1    Vinkemeier, U.2    Zhao, Y.3    Jeruzalmi, D.4    Darnell Jr., J.E.5    Kuriyan, J.6
  • 27
    • 0032499801 scopus 로고    scopus 로고
    • Three-dimensional structure of the Stat3β homodimer bound to DNA
    • Becker, S., Groner, B., and Muller, C. W. (1998) Three-dimensional structure of the Stat3β homodimer bound to DNA. Nature 394, 145-151
    • (1998) Nature , vol.394 , pp. 145-151
    • Becker, S.1    Groner, B.2    Muller, C.W.3
  • 28
    • 0037007207 scopus 로고    scopus 로고
    • Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-α
    • McBride, K. M., Banninger, G., McDonald, C., and Reich, N. C. (2002) Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-α. EMBO J. 21, 1754-1763
    • (2002) EMBO J , vol.21 , pp. 1754-1763
    • McBride, K.M.1    Banninger, G.2    McDonald, C.3    Reich, N.C.4
  • 29
    • 0041344551 scopus 로고    scopus 로고
    • Importin nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein
    • Melen, K., Fagerlund, R., Franke, J., Kohler, M., Kinnunen, L., and Julkunen, I. (2003) Importin nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein. J. Biol. Chem. 278, 28193-28200
    • (2003) J. Biol. Chem , vol.278 , pp. 28193-28200
    • Melen, K.1    Fagerlund, R.2    Franke, J.3    Kohler, M.4    Kinnunen, L.5    Julkunen, I.6
  • 30
    • 0036470732 scopus 로고    scopus 로고
    • Constitutive and IFN-γ-induced nuclear import of STAT1 proceed through independent pathways
    • Meyer, T., Begitt, A., Lodige, I., van Rossum, M., and Vinkemeier, U. (2002) Constitutive and IFN-γ-induced nuclear import of STAT1 proceed through independent pathways. EMBO J. 21, 344-354
    • (2002) EMBO J , vol.21 , pp. 344-354
    • Meyer, T.1    Begitt, A.2    Lodige, I.3    van Rossum, M.4    Vinkemeier, U.5
  • 31
    • 20444400857 scopus 로고    scopus 로고
    • STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-α3
    • Liu, L., McBride, K. M., and Reich, N. C. (2005) STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-α3. Proc. Natl. Acad. Sci. U. S. A. 102, 8150-8155
    • (2005) Proc. Natl. Acad. Sci. U. S. A , vol.102 , pp. 8150-8155
    • Liu, L.1    McBride, K.M.2    Reich, N.C.3
  • 32
    • 0030795422 scopus 로고    scopus 로고
    • Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-α-stimulated transcription factor ISGF3
    • Martinez-Moczygemba, M., Gutch, M. J., French, D. L., and Reich, N. C. (1997) Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-α-stimulated transcription factor ISGF3. J. Biol. Chem. 272, 20070-20076
    • (1997) J. Biol. Chem , vol.272 , pp. 20070-20076
    • Martinez-Moczygemba, M.1    Gutch, M.J.2    French, D.L.3    Reich, N.C.4
  • 33
    • 0030737957 scopus 로고    scopus 로고
    • Growth hormone-induced tyrosyl phosphorylation and deoxyribonucleic acid binding activity of Stat5A and Stat5B
    • Smit, L. S., Vanderkuur, J. A., Stimage, A., Han, Y., Luo, G., Yu-Lee, L. Y., Schwartz, J., and Carter-Su, C. (1997) Growth hormone-induced tyrosyl phosphorylation and deoxyribonucleic acid binding activity of Stat5A and Stat5B. Endocrinology 138, 3426-3434
    • (1997) Endocrinology , vol.138 , pp. 3426-3434
    • Smit, L.S.1    Vanderkuur, J.A.2    Stimage, A.3    Han, Y.4    Luo, G.5    Yu-Lee, L.Y.6    Schwartz, J.7    Carter-Su, C.8
  • 34
    • 0034669111 scopus 로고    scopus 로고
    • Nuclear export signal located within the DNA-binding domain of the STAT1transcription factor
    • McBride, K. M., McDonald, C., and Reich, N. C. (2000) Nuclear export signal located within the DNA-binding domain of the STAT1transcription factor. EMBO J. 19, 6196-6206
    • (2000) EMBO J , vol.19 , pp. 6196-6206
    • McBride, K.M.1    McDonald, C.2    Reich, N.C.3
  • 35
    • 34247135913 scopus 로고    scopus 로고
    • Classical nuclear localization signals: Definition, function, and interaction with importin α
    • Lange, A., Mills, R. E., Lange, C. J., Stewart, M., Devine, S. E., and Corbett, A. H. (2007) Classical nuclear localization signals: definition, function, and interaction with importin α. J. Biol. Chem. 282, 5101-5105
    • (2007) J. Biol. Chem , vol.282 , pp. 5101-5105
    • Lange, A.1    Mills, R.E.2    Lange, C.J.3    Stewart, M.4    Devine, S.E.5    Corbett, A.H.6
  • 38
    • 4544341121 scopus 로고    scopus 로고
    • STAT2 nuclear trafficking
    • Banninger, G., and Reich, N. C. (2004) STAT2 nuclear trafficking. J. Biol. Chem. 279, 39199-39206
    • (2004) J. Biol. Chem , vol.279 , pp. 39199-39206
    • Banninger, G.1    Reich, N.C.2
  • 39
    • 13844298835 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling revealed by FRAP and FLIP technologies
    • Koster, M., Frahm, T., and Hauser, H. (2005) Nucleocytoplasmic shuttling revealed by FRAP and FLIP technologies. Curr. Opin. Biotechnol. 16, 28-34
    • (2005) Curr. Opin. Biotechnol , vol.16 , pp. 28-34
    • Koster, M.1    Frahm, T.2    Hauser, H.3
  • 40
    • 3042552337 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1
    • Marg, A., Shan, Y., Meyer, T., Meissner, T., Brandenburg, M., and Vinkemeier, U. (2004) Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1. J. Cell Biol. 165, 823-833
    • (2004) J. Cell Biol , vol.165 , pp. 823-833
    • Marg, A.1    Shan, Y.2    Meyer, T.3    Meissner, T.4    Brandenburg, M.5    Vinkemeier, U.6
  • 43
    • 0040017820 scopus 로고    scopus 로고
    • A functional DNA binding domain is required for growth hormone-induced nuclear accumulation of Stat5B
    • Herrington, J., Rui, L., Luo, G., Yu-Lee, L. Y., and Carter-Su, C. (1999) A functional DNA binding domain is required for growth hormone-induced nuclear accumulation of Stat5B. J. Biol. Chem. 274, 5138-5145
    • (1999) J. Biol. Chem , vol.274 , pp. 5138-5145
    • Herrington, J.1    Rui, L.2    Luo, G.3    Yu-Lee, L.Y.4    Carter-Su, C.5
  • 44
    • 0036569411 scopus 로고    scopus 로고
    • Stat5B shuttles between cytoplasm and nucleus in a cytokine-dependent and -independent manner
    • Zeng, R., Aoki, Y., Yoshida, M., Arai, K., and Watanabe, S. (2002) Stat5B shuttles between cytoplasm and nucleus in a cytokine-dependent and -independent manner. J. Immunol. 168, 4567-4575
    • (2002) J. Immunol , vol.168 , pp. 4567-4575
    • Zeng, R.1    Aoki, Y.2    Yoshida, M.3    Arai, K.4    Watanabe, S.5
  • 46
    • 0035844291 scopus 로고    scopus 로고
    • Arginine/ lysine-rich structural element is involved in interferon-induced nuclear import of STATs
    • Melen, K., Kinnunen, L., and Julkunen, I. (2001) Arginine/ lysine-rich structural element is involved in interferon-induced nuclear import of STATs. J. Biol. Chem. 276, 16447-16455
    • (2001) J. Biol. Chem , vol.276 , pp. 16447-16455
    • Melen, K.1    Kinnunen, L.2    Julkunen, I.3
  • 47
    • 0029958032 scopus 로고    scopus 로고
    • Interferon-γ-dependent nuclear import of Stat1 is mediated by the GTPase activity of Ran/TC4
    • Sekimoto, T., Nakajima, K., Tachibana, T., Hirano, T., and Yoneda, Y. (1996) Interferon-γ-dependent nuclear import of Stat1 is mediated by the GTPase activity of Ran/TC4. J. Biol. Chem. 271, 31017-31020
    • (1996) J. Biol. Chem , vol.271 , pp. 31017-31020
    • Sekimoto, T.1    Nakajima, K.2    Tachibana, T.3    Hirano, T.4    Yoneda, Y.5
  • 48
    • 0028318159 scopus 로고
    • Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression
    • Nishi, K., Yoshida, M., Fujiwara, D., Nishikawa, M., Horinouchi, S., and Beppu, T. (1994) Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression. J. Biol. Chem. 269, 6320-6324
    • (1994) J. Biol. Chem , vol.269 , pp. 6320-6324
    • Nishi, K.1    Yoshida, M.2    Fujiwara, D.3    Nishikawa, M.4    Horinouchi, S.5    Beppu, T.6
  • 49
    • 0042206459 scopus 로고    scopus 로고
    • A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation
    • Ma, J., Zhang, T., Novotny-Diermayr, V., Tan, A. L., and Cao, X. (2003) A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation. J. Biol. Chem. 278, 29252-29260
    • (2003) J. Biol. Chem , vol.278 , pp. 29252-29260
    • Ma, J.1    Zhang, T.2    Novotny-Diermayr, V.3    Tan, A.L.4    Cao, X.5
  • 50
    • 0028817880 scopus 로고
    • Jak-STAT signaling induced by the v-abl oncogene
    • Danial, N. N., Pernis, A., and Rothman, P. B. (1995) Jak-STAT signaling induced by the v-abl oncogene. Science 269, 1875-1877
    • (1995) Science , vol.269 , pp. 1875-1877
    • Danial, N.N.1    Pernis, A.2    Rothman, P.B.3
  • 51
    • 0034254726 scopus 로고    scopus 로고
    • How Stat1 mediates constitutive gene expression: A complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene
    • Chatterjee-Kishore, M., Wright, K. L., Ting, J. P., and Stark, G. R. (2000) How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene. EMBO J. 19, 4111-4122
    • (2000) EMBO J , vol.19 , pp. 4111-4122
    • Chatterjee-Kishore, M.1    Wright, K.L.2    Ting, J.P.3    Stark, G.R.4


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