TGFβ-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2

EMBO Reports

Volumn 9, Issue 10, 2008, Pages 990-997

  Ramesh, Sneha ^a   Qi, Xiao Jun ^a   Wildey, Gary M ^a   Robinson, Janet ^b   Molkentin, Jeffery ^c   Letterio, John ^b   Howe, Philip H ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIM PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 2; PROTEOME; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE OVEREXPRESSION; GENETIC CODE; LIVER CELL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; B-LYMPHOCYTES; CELL LINE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEPATOCYTES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PROTEIN TYROSINE PHOSPHATASES; PROTO-ONCOGENE PROTEINS; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

MUS;

EID: 53249137795     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2008.158     Document Type: Article

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