Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.

Circulation research

Volumn 112, Issue 1, 2013, Pages 48-56

  Auger Messier, Mannix ^a   Accornero, Federica ^b   Goonasekera, Sanjeewa A ^b   Bueno, Orlando F ^b   Lorenz, John N ^b   van Berlo, Jop H ^b   Willette, Robert N ^b   Molkentin, Jeffery D ^b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM BINDING PROTEIN; DUSP1 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MKP2 PROTEIN, MOUSE; PHOSPHOLAMBAN; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE PHOSPHATASE;

129 MOUSE; ANIMAL; ARTICLE; C57BL MOUSE; CARDIOMYOPATHY; CELL CULTURE; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; HEART CONTRACTION; HEART MUSCLE CELL; HEMODYNAMICS; METABOLISM; MOUSE; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TIME;

ANIMALS; CALCIUM; CALCIUM-BINDING PROTEINS; CARDIOMYOPATHIES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DUAL SPECIFICITY PHOSPHATASE 1; ENZYME ACTIVATION; FIBROBLASTS; GENE EXPRESSION REGULATION; HEMODYNAMICS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN TYROSINE PHOSPHATASES; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84874425321     PISSN: None     EISSN: 15244571     Source Type: None    
DOI: 10.1161/CIRCRESAHA.112.272963     Document Type: Article

References (0)