-
1
-
-
14444273439
-
Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
-
Finzi D, Hermankova M, Pierson T, et al. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 1997; 278: 1295-1300.
-
(1997)
Science
, vol.278
, pp. 1295-1300
-
-
Finzi, D.1
Hermankova, M.2
Pierson, T.3
-
2
-
-
0030712305
-
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
-
Wong JK, Hezareh M, Günthard HF, et al. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science 1997; 278: 1291-1295.
-
(1997)
Science
, vol.278
, pp. 1291-1295
-
-
Wong, J.K.1
Hezareh, M.2
Günthard, H.F.3
-
3
-
-
0030659177
-
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
-
Chun TW, Stuyver L, Mizell SB, et al. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy. Proc Natl Acad Sci USA 1997; 94: 13193-13197.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13193-13197
-
-
Chun, T.W.1
Stuyver, L.2
Mizell, S.B.3
-
4
-
-
84893830170
-
Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues
-
Fletcher CV, Staskus K, Wietgrefe SW, et al. Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues. Proc Natl Acad Sci 2014; 111: 2307-2312.
-
(2014)
Proc Natl Acad Sci
, vol.111
, pp. 2307-2312
-
-
Fletcher, C.V.1
Staskus, K.2
Wietgrefe, S.W.3
-
5
-
-
0038579210
-
Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
-
Siliciano JD, Kajdas J, Finzi D, et al. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat Med 2003; 9: 727-728.
-
(2003)
Nat Med
, vol.9
, pp. 727-728
-
-
Siliciano, J.D.1
Kajdas, J.2
Finzi, D.3
-
6
-
-
68349139711
-
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
-
Chomont N, El-Far M, Ancuta P, et al. HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat Med 2009; 15: 893-900.
-
(2009)
Nat Med
, vol.15
, pp. 893-900
-
-
Chomont, N.1
El-Far, M.2
Ancuta, P.3
-
7
-
-
84878542117
-
Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells
-
Hatano H, Jain V, Hunt PW, et al. Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells. J Infect Dis 2013; 208: 50-56.
-
(2013)
J Infect Dis
, vol.208
, pp. 50-56
-
-
Hatano, H.1
Jain, V.2
Hunt, P.W.3
-
8
-
-
84908448373
-
CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells
-
Cockerham LR, Siliciano JD, Sinclair E, et al. CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells. Plos One 2014; 9: e110731.
-
(2014)
Plos One
, vol.9
, pp. e110731
-
-
Cockerham, L.R.1
Siliciano, J.D.2
Sinclair, E.3
-
9
-
-
34249883292
-
Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: Implications for eradication of virus
-
Chun T-W, Justement JS, Moir S, et al. Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus. J Infect Dis 2007; 195: 1762-1764.
-
(2007)
J Infect Dis
, vol.195
, pp. 1762-1764
-
-
Chun, T.-W.1
Justement, J.S.2
Moir, S.3
-
10
-
-
84865108061
-
As good as it gets? the problem of HIV persistence despite antiretroviral drugs
-
Sigal A, Baltimore D. As good as it gets? The problem of HIV persistence despite antiretroviral drugs. Cell Host Microbe 2012; 12: 132-138.
-
(2012)
Cell Host Microbe
, vol.12
, pp. 132-138
-
-
Sigal, A.1
Baltimore, D.2
-
11
-
-
77950537810
-
HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects
-
Buzon MJ, Massanella M, Llibre JM, et al. HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects. Nat Med 2010; 16: 460-465.
-
(2010)
Nat Med
, vol.16
, pp. 460-465
-
-
Buzon, M.J.1
Massanella, M.2
Llibre, J.M.3
-
12
-
-
78549245806
-
Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy
-
Yukl SA, Shergill AK, Mcquaid K, et al. Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy. AIDS (London, England) 2010; 24: 2451-2460.
-
(2010)
AIDS (London, England)
, vol.24
, pp. 2451-2460
-
-
Yukl, S.A.1
Shergill, A.K.2
Mcquaid, K.3
-
13
-
-
27644524761
-
HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir
-
Chun T-W, Nickle DC, Justement JS, et al. HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir. J Clin Invest 2005; 115: 3250-3255.
-
(2005)
J Clin Invest
, vol.115
, pp. 3250-3255
-
-
Chun, T.-W.1
Nickle, D.C.2
Justement, J.S.3
-
14
-
-
78149417719
-
Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy
-
Yukl SA, Gianella S, Sinclair E, et al. Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy. J Infect Dis 2010; 202: 1553-1561.
-
(2010)
J Infect Dis
, vol.202
, pp. 1553-1561
-
-
Yukl, S.A.1
Gianella, S.2
Sinclair, E.3
-
15
-
-
4644342929
-
CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
-
Brenchley JM, Schacker TW, Ruff LE, et al. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J Exp Med 2004; 200: 749-759.
-
(2004)
J Exp Med
, vol.200
, pp. 749-759
-
-
Brenchley, J.M.1
Schacker, T.W.2
Ruff, L.E.3
-
16
-
-
80054995389
-
Human immunodeficiency virus infects human seminal vesicles in vitro and in vivo
-
Deleage C, Moreau M, Rioux-Leclercq N, et al. Human immunodeficiency virus infects human seminal vesicles in vitro and in vivo. Am J Pathol 2011; 179: 2397-2408.
-
(2011)
Am J Pathol
, vol.179
, pp. 2397-2408
-
-
Deleage, C.1
Moreau, M.2
Rioux-Leclercq, N.3
-
17
-
-
0027538456
-
HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease
-
Pantaleo G, Graziosi C, Demarest JF, et al. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature 1993; 362: 355-358.
-
(1993)
Nature
, vol.362
, pp. 355-358
-
-
Pantaleo, G.1
Graziosi, C.2
Demarest, J.F.3
-
18
-
-
77649117525
-
Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS
-
North TW, Higgins J, Deere JD, et al. Viral sanctuaries during highly active antiretroviral therapy in a nonhuman primate model for AIDS. J Virol 2010; 84: 2913-2922.
-
(2010)
J Virol
, vol.84
, pp. 2913-2922
-
-
North, T.W.1
Higgins, J.2
Deere, J.D.3
-
19
-
-
50249123398
-
Immune reconstitution in the sigmoid colon after long-term HIV therapy
-
Sheth PM, Chege D, Shin LYY, et al. Immune reconstitution in the sigmoid colon after long-term HIV therapy. Mucosal Immunol 2008; 1: 382-388.
-
(2008)
Mucosal Immunol
, vol.1
, pp. 382-388
-
-
Sheth, P.M.1
Chege, D.2
Lyy, S.3
-
20
-
-
40549092339
-
Persistence of HIV in gutassociated lymphoid tissue despite long-term antiretroviral therapy
-
Chun T-W, Nickle DC, Justement JS, et al. Persistence of HIV in gutassociated lymphoid tissue despite long-term antiretroviral therapy. J Infect Dis 2008; 197: 714-720.
-
(2008)
J Infect Dis
, vol.197
, pp. 714-720
-
-
Chun, T.-W.1
Nickle, D.C.2
Justement, J.S.3
-
21
-
-
84924365877
-
Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption
-
Rothenberger MK, Keele BF, Wietgrefe SW, et al. Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption. Proc Nat Acad Sci 2015; 112: E1126-E1134.
-
(2015)
Proc Nat Acad Sci
, vol.112
, pp. E1126-E1134
-
-
Rothenberger, M.K.1
Keele, B.F.2
Wietgrefe, S.W.3
-
22
-
-
0032518290
-
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
-
Kim RB, Fromm MF, Wandel C, et al. The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J Clin Invest 1998; 101: 289-294.
-
(1998)
J Clin Invest
, vol.101
, pp. 289-294
-
-
Kim, R.B.1
Fromm, M.F.2
Wandel, C.3
-
23
-
-
83455206864
-
Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: The fetal compartment (placenta and amniotic fluid)
-
Else LJ, Taylor S, Back DJ, Khoo SH. Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid). Antivir Ther (Lond) 2011; 16: 1139-1147.
-
(2011)
Antivir Ther (Lond)
, vol.16
, pp. 1139-1147
-
-
Else, L.J.1
Taylor, S.2
Back, D.J.3
Khoo, S.H.4
-
24
-
-
84931274825
-
Mass spectrometry imaging reveals heterogeneous efavirenz distribution within putative HIV reservoirs
-
Thompson CG, Bokhart MT, Sykes C, et al. Mass spectrometry imaging reveals heterogeneous efavirenz distribution within putative HIV reservoirs. Antimicrob Agents Chemother 2015; 59: 2944-2948.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 2944-2948
-
-
Thompson, C.G.1
Bokhart, M.T.2
Sykes, C.3
-
25
-
-
80052395837
-
Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy
-
Sigal A, Kim JT, Balazs AB, et al. Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy. Nature 2011; 477: 95-98.
-
(2011)
Nature
, vol.477
, pp. 95-98
-
-
Sigal, A.1
Kim, J.T.2
Balazs, A.B.3
-
26
-
-
38349181049
-
HIV-1 induced activation of CD4+ T cells creates new targets for HIV-1 infection in human lymphoid tissue ex vivo
-
Biancotto A, Iglehart SJ, Vanpouille C, et al. HIV-1 induced activation of CD4+ T cells creates new targets for HIV-1 infection in human lymphoid tissue ex vivo. Blood 2008; 111: 699-704.
-
(2008)
Blood
, vol.111
, pp. 699-704
-
-
Biancotto, A.1
Iglehart, S.J.2
Vanpouille, C.3
-
27
-
-
79251480064
-
Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue
-
Doitsh G, Cavrois M, Lassen KG, et al. Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue. Cell 2010; 143: 789-801.
-
(2010)
Cell
, vol.143
, pp. 789-801
-
-
Doitsh, G.1
Cavrois, M.2
Lassen, K.G.3
-
28
-
-
84892739389
-
Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
-
Doitsh G, Galloway NLK, Geng X, et al. Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature 2014; 505: 509-514.
-
(2014)
Nature
, vol.505
, pp. 509-514
-
-
Doitsh, G.1
Nlk, G.2
Geng, X.3
-
29
-
-
84892946076
-
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV
-
Monroe KM, Yang Z, Johnson JR, et al. IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science 2014; 343: 428-432.
-
(2014)
Science
, vol.343
, pp. 428-432
-
-
Monroe, K.M.1
Yang, Z.2
Johnson, J.R.3
-
30
-
-
0036801658
-
Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis
-
Schacker TW, Nguyen PL, Beilman GJ, et al. Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis. J Clin Invest 2002; 110: 1133-1139.
-
(2002)
J Clin Invest
, vol.110
, pp. 1133-1139
-
-
Schacker, T.W.1
Nguyen, P.L.2
Beilman, G.J.3
-
31
-
-
33646689587
-
Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection
-
Schacker TW, Brenchley JM, Beilman GJ, et al. Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection. Clin Vaccine Immunol 2006; 13: 556-560.
-
(2006)
Clin Vaccine Immunol
, vol.13
, pp. 556-560
-
-
Schacker, T.W.1
Brenchley, J.M.2
Beilman, G.J.3
-
32
-
-
79952216365
-
Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections
-
Zeng M, Smith AJ, Wietgrefe SW, et al. Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections. J Clin Invest 2011; 121: 998-1008.
-
(2011)
J Clin Invest
, vol.121
, pp. 998-1008
-
-
Zeng, M.1
Smith, A.J.2
Wietgrefe, S.W.3
-
33
-
-
84865997747
-
Expansion of HIV-specific T follicular helper cells in chronic HIV infection
-
Lindqvist M, van Lunzen J, Soghoian DZ, et al. Expansion of HIV-specific T follicular helper cells in chronic HIV infection. J Clin Invest 2012; 122: 3271-3280.
-
(2012)
J Clin Invest
, vol.122
, pp. 3271-3280
-
-
Lindqvist, M.1
Van Lunzen, J.2
Soghoian, D.Z.3
-
34
-
-
84865395104
-
CD4 T follicular helper cell dynamics during SIV infection
-
Petrovas C, Yamamoto T, Gerner MY, et al. CD4 T follicular helper cell dynamics during SIV infection. J Clin Invest 2012; 122: 3281-3294.
-
(2012)
J Clin Invest
, vol.122
, pp. 3281-3294
-
-
Petrovas, C.1
Yamamoto, T.2
Gerner, M.Y.3
-
35
-
-
84859415408
-
Spatial alterations between CD4+ T follicular helper, B, and CD8+ T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape
-
Hong JJ, Amancha PK, Rogers K, Ansari AA, Villinger F. Spatial alterations between CD4+ T follicular helper, B, and CD8+ T cells during simian immunodeficiency virus infection: T/B cell homeostasis, activation, and potential mechanism for viral escape. J Immunol 2012; 188: 3247-3256.
-
(2012)
J Immunol
, vol.188
, pp. 3247-3256
-
-
Hong, J.J.1
Amancha, P.K.2
Rogers, K.3
Ansari, A.A.4
Villinger, F.5
-
36
-
-
34249800097
-
CTL fail to accumulate at sites of HIV- 1 replication in lymphoid tissue
-
Connick E, Mattila T, Folkvord JM, et al. CTL fail to accumulate at sites of HIV- 1 replication in lymphoid tissue. J Immunol 2007; 178: 6975-6983.
-
(2007)
J Immunol
, vol.178
, pp. 6975-6983
-
-
Connick, E.1
Mattila, T.2
Folkvord, J.M.3
-
37
-
-
84874519282
-
Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production
-
Perreau M, Savoye A-L, De Crignis E, et al. Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production. J Exp Med 2013; 210: 143-156.
-
(2013)
J Exp Med
, vol.210
, pp. 143-156
-
-
Perreau, M.1
Savoye, A.-L.2
De Crignis, E.3
-
38
-
-
84930635082
-
Comprehensive serological profiling of human populations using a synthetic human virome
-
Xu GJ, Kula T, Xu Q, et al. Comprehensive serological profiling of human populations using a synthetic human virome. Science 2015; 348: aaa0698-aaa0698.
-
(2015)
Science
, vol.348
, pp. aaa0698-aaa0698
-
-
Xu, G.J.1
Kula, T.2
Xu, Q.3
-
39
-
-
20444379970
-
Lymphoid follicles are sites of heightened human immunodeficiency virus type 1 (HIV-1) replication and reduced antiretroviral effector mechanisms
-
Folkvord JM, Armon C, Connick E. Lymphoid follicles are sites of heightened human immunodeficiency virus type 1 (HIV-1) replication and reduced antiretroviral effector mechanisms. AIDS Res Hum Retroviruses 2005; 21: 363-370.
-
(2005)
AIDS Res Hum Retroviruses
, vol.21
, pp. 363-370
-
-
Folkvord, J.M.1
Armon, C.2
Connick, E.3
-
40
-
-
84922611542
-
B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers
-
Fukazawa Y, Lum R, Okoye AA, et al. B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers. Nat Med 2015; 21: 132-139.
-
(2015)
Nat Med
, vol.21
, pp. 132-139
-
-
Fukazawa, Y.1
Lum, R.2
Okoye, A.A.3
-
41
-
-
84860345691
-
Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: A randomized 48-week study
-
Llibre JM, Buzon MJ, Massanella M, et al. Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study. Antivir Ther (Lond) 2012; 17: 355-364.
-
(2012)
Antivir Ther (Lond)
, vol.17
, pp. 355-364
-
-
Llibre, J.M.1
Buzon, M.J.2
Massanella, M.3
-
42
-
-
84879774999
-
Dynamics of CD8 T-cell activation after discontinuation of HIV treatment intensification
-
Massanella M, Esteve A, Buzon MJ, et al. Dynamics of CD8 T-cell activation after discontinuation of HIV treatment intensification. J Acquir Immune Defic Syndr 2013; 63: 152-160.
-
(2013)
J Acquir Immune Defic Syndr
, vol.63
, pp. 152-160
-
-
Massanella, M.1
Esteve, A.2
Buzon, M.J.3
-
43
-
-
84885411247
-
Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: A randomized, placebo-controlled trial
-
Hatano H, Strain MC, Scherzer R, et al. Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: a randomized, placebo-controlled trial. J Infect Dis 2013; 208: 1436-1442.
-
(2013)
J Infect Dis
, vol.208
, pp. 1436-1442
-
-
Hatano, H.1
Strain, M.C.2
Scherzer, R.3
-
44
-
-
84866707088
-
The effect of intensification with raltegravir on the HIV-1 reservoir of latently infected memory CD4 T cells in suppressed patients
-
Vallejo A, Gutié rrez C, Hernández-Novoa B, et al. The effect of intensification with raltegravir on the HIV-1 reservoir of latently infected memory CD4 T cells in suppressed patients. AIDS 2012; 26: 1885-1894.
-
(2012)
AIDS
, vol.26
, pp. 1885-1894
-
-
Vallejo, A.1
Gutiérrez, C.2
Hernández-Novoa, B.3
-
45
-
-
84859752894
-
No effect of raltegravir intensification on viral replication markers in the blood of HIV-1-infected patients receiving antiretroviral therapy
-
Gandhi RT, Coombs RW, Chan ES, et al. No effect of raltegravir intensification on viral replication markers in the blood of HIV-1-infected patients receiving antiretroviral therapy. J Acquir Immune Defic Syndr 2012; 59: 229-235.
-
(2012)
J Acquir Immune Defic Syndr
, vol.59
, pp. 229-235
-
-
Gandhi, R.T.1
Coombs, R.W.2
Chan, E.S.3
-
46
-
-
75649108956
-
No evidence for decay of the latent reservoir in HIV-1-infected patients receiving intensive enfuvirtide-containing antiretroviral therapy
-
Gandhi RT, Bosch RJ, Aga E, et al. No evidence for decay of the latent reservoir in HIV-1-infected patients receiving intensive enfuvirtide-containing antiretroviral therapy. J Infect Dis 2010; 201: 293-296.
-
(2010)
J Infect Dis
, vol.201
, pp. 293-296
-
-
Gandhi, R.T.1
Bosch, R.J.2
Aga, E.3
-
47
-
-
77956856393
-
The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: A randomized controlled trial
-
e1000321
-
Gandhi RT, Zheng L, Bosch RJ, et al. The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial. PLoS Med 2010; 7: ; pii: e1000321. doi: 10.1371/journal.pmed.1000321.
-
(2010)
PLoS Med
, vol.7
-
-
Gandhi, R.T.1
Zheng, L.2
Bosch, R.J.3
-
48
-
-
79953000877
-
A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response
-
Hatano H, Hayes TL, Dahl V, et al. A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response. J Infect Dis 2011; 203: 960-968.
-
(2011)
J Infect Dis
, vol.203
, pp. 960-968
-
-
Hatano, H.1
Hayes, T.L.2
Dahl, V.3
-
49
-
-
84870242082
-
Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recovery
-
Massanella M, Negredo E, Puig J, et al. Raltegravir intensification shows differing effects on CD8 and CD4 T cells in HIV-infected HAART-suppressed individuals with poor CD4 T-cell recovery. AIDS 2012; 26: 2285-2293.
-
(2012)
AIDS
, vol.26
, pp. 2285-2293
-
-
Massanella, M.1
Negredo, E.2
Puig, J.3
-
50
-
-
84887314399
-
Early but limited effects of raltegravir intensification on CD4 T cell reconstitution in HIV-infected patients with an immunodiscordant response to antiretroviral therapy
-
Negredo E, Massanella M, Puertas MC, et al. Early but limited effects of raltegravir intensification on CD4 T cell reconstitution in HIV-infected patients with an immunodiscordant response to antiretroviral therapy. J Antimicrob Chemother 2013; 68: 2358-2362.
-
(2013)
J Antimicrob Chemother
, vol.68
, pp. 2358-2362
-
-
Negredo, E.1
Massanella, M.2
Puertas, M.C.3
-
51
-
-
84870501232
-
A pilot study to assess inflammatory biomarker changes when raltegravir is added to a virologically suppressive HAART regimen in HIV-1-infected patients with limited immunological responses
-
Lichtenstein KA, Armon C, Nagabhushanam V, et al. A pilot study to assess inflammatory biomarker changes when raltegravir is added to a virologically suppressive HAART regimen in HIV-1-infected patients with limited immunological responses. Antivir Ther (Lond) 2012; 17: 1301-1309.
-
(2012)
Antivir Ther (Lond)
, vol.17
, pp. 1301-1309
-
-
Lichtenstein, K.A.1
Armon, C.2
Nagabhushanam, V.3
-
52
-
-
39349088126
-
Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy
-
Hunt PW, Brenchley J, Sinclair E, et al. Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. J Infect Dis 2008; 197: 126-133.
-
(2008)
J Infect Dis
, vol.197
, pp. 126-133
-
-
Hunt, P.W.1
Brenchley, J.2
Sinclair, E.3
-
53
-
-
84887290531
-
Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers
-
Hatano H, Yukl SA, Ferre AL, et al. Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers. PLoS Pathog 2013; 9: e1003691.
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003691
-
-
Hatano, H.1
Yukl, S.A.2
Ferre, A.L.3
-
54
-
-
84880421532
-
The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: A randomized trial
-
Hunt PW, Shulman NS, Hayes TL, et al. The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial. Blood 2013; 121: 4635-4646.
-
(2013)
Blood
, vol.121
, pp. 4635-4646
-
-
Hunt, P.W.1
Shulman, N.S.2
Hayes, T.L.3
-
55
-
-
82955187838
-
Intensification of antiretroviral therapy with a CCR5 antagonist in patients with chronic HIV-1 infection: Effect on T cells latently infected
-
Gutié rrez C, Díaz L, Vallejo A, et al. Intensification of antiretroviral therapy with a CCR5 antagonist in patients with chronic HIV-1 infection: effect on T cells latently infected. Plos One 2011; 6: e27864.
-
(2011)
Plos One
, vol.6
, pp. e27864
-
-
Gutiérrez, C.1
Díaz, L.2
Vallejo, A.3
-
56
-
-
84900477263
-
Maraviroc intensification in patients with suppressed HIV viremia has limited effects on CD4+ T cell recovery and gene expression
-
Beliakova-Bethell N, Jain S, Woelk CH, et al. Maraviroc intensification in patients with suppressed HIV viremia has limited effects on CD4+ T cell recovery and gene expression. Antiviral Res 2014; 107: 42-49.
-
(2014)
Antiviral Res
, vol.107
, pp. 42-49
-
-
Beliakova-Bethell, N.1
Jain, S.2
Woelk, C.H.3
-
57
-
-
84895487305
-
Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV
-
Tebas P, Stein D, Tang WW, et al. Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. N Engl J Med 2014; 370: 901-910.
-
(2014)
N Engl J Med
, vol.370
, pp. 901-910
-
-
Tebas, P.1
Stein, D.2
Tang, W.W.3
-
58
-
-
84957452808
-
Decay of the HIV reservoir post autologous transfer of ZFN CCR5 modified CD4 T cells (SB-728-T) correlates with generation of a T memory stem cell-like population and enhanced HIVspecific CD8 T cell polyfunctionality
-
Boston, USA
-
Zeidan J, Lee G, Fourati S, et al. Decay of the HIV reservoir post autologous transfer of ZFN CCR5 modified CD4 T cells (SB-728-T) correlates with generation of a T memory stem cell-like population and enhanced HIVspecific CD8 T cell polyfunctionality. Keystone Symposia Mechanisms HIV Persistence: Implications for a Cure 2015; Boston, USA.
-
(2015)
Keystone Symposia Mechanisms HIV Persistence: Implications for A Cure
-
-
Zeidan, J.1
Lee, G.2
Fourati, S.3
-
59
-
-
53449093632
-
Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections
-
Brenchley JM, Paiardini M, Knox KS, et al. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 2008; 112: 2826-2835.
-
(2008)
Blood
, vol.112
, pp. 2826-2835
-
-
Brenchley, J.M.1
Paiardini, M.2
Knox, K.S.3
-
60
-
-
33845532053
-
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
-
Brenchley JM, Price DA, Schacker TW, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. NatMed 2006; 12: 1365-1371.
-
(2006)
NatMed
, vol.12
, pp. 1365-1371
-
-
Brenchley, J.M.1
Price, D.A.2
Schacker, T.W.3
-
61
-
-
79953735335
-
Sigmoid Th17 populations, the HIV latent reservoir, and microbial translocation in men on long-term antiretroviral therapy
-
Chege D, Sheth PM, Kain T, et al. Sigmoid Th17 populations, the HIV latent reservoir, and microbial translocation in men on long-term antiretroviral therapy. AIDS (London, England) 2011; 25: 741-749.
-
(2011)
AIDS (London, England)
, vol.25
, pp. 741-749
-
-
Chege, D.1
Sheth, P.M.2
Kain, T.3
-
62
-
-
84883417251
-
Mucosal Th17 cell function is altered during HIV infection and is an independent predictor of systemic immune activation
-
Kim CJ, McKinnon LR, Kovacs C, et al. Mucosal Th17 cell function is altered during HIV infection and is an independent predictor of systemic immune activation. J Immunol 2013; 191: 2164-2173.
-
(2013)
J Immunol
, vol.191
, pp. 2164-2173
-
-
Kim, C.J.1
McKinnon, L.R.2
Kovacs, C.3
-
63
-
-
84919665923
-
PLOS pathogens: Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation
-
Schuetz A, Deleage C, Sereti I, et al. PLOS pathogens: initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation. PLoS Pathog 2014; 10: e1004543.
-
(2014)
PLoS Pathog
, vol.10
, pp. e1004543
-
-
Schuetz, A.1
Deleage, C.2
Sereti, I.3
-
64
-
-
84957452809
-
Interleukin-21 decreases residual inflammation and reduces the virus reservoir in ART-treated, SIV-infected rhesus macaques
-
(In press)
-
Micci L, Ryan ES, Fromentin R, et al. Interleukin-21 decreases residual inflammation and reduces the virus reservoir in ART-treated, SIV-infected rhesus macaques. J Clin Invest 2015. (In press).
-
(2015)
J Clin Invest
-
-
Micci, L.1
Ryan, E.S.2
Fromentin, R.3
-
66
-
-
77953631013
-
Effect of treating co-infections on HIV-1 viral load: A systematic review
-
Modjarrad K, Vermund SH. Effect of treating co-infections on HIV-1 viral load: a systematic review. Lancet Infect Dis 2010; 10: 455-463.
-
(2010)
Lancet Infect Dis
, vol.10
, pp. 455-463
-
-
Modjarrad, K.1
Vermund, S.H.2
-
67
-
-
0034968096
-
Attrition of bystander CD8 T cells during virus-induced T-cell and interferon responses
-
McNally JM, Zarozinski CC, Lin MY, et al. Attrition of bystander CD8 T cells during virus-induced T-cell and interferon responses. J Virol 2001; 75: 5965-5976.
-
(2001)
J Virol
, vol.75
, pp. 5965-5976
-
-
McNally, J.M.1
Zarozinski, C.C.2
Lin, M.Y.3
-
68
-
-
84863176906
-
Associations between virologic and immunologic dynamics in blood and in the male genital tract
-
Gianella S, Strain MC, Rought SE, et al. Associations between virologic and immunologic dynamics in blood and in the male genital tract. J Virol 2012; 86: 1307-1315.
-
(2012)
J Virol
, vol.86
, pp. 1307-1315
-
-
Gianella, S.1
Strain, M.C.2
Rought, S.E.3
-
69
-
-
84874237795
-
Cytomegalovirus DNA in semen and blood is associated with higher levels of proviral HIV DNA
-
Gianella S, Anderson CM, Vargas MV, et al. Cytomegalovirus DNA in semen and blood is associated with higher levels of proviral HIV DNA. J Infect Dis 2013; 207: 898-902.
-
(2013)
J Infect Dis
, vol.207
, pp. 898-902
-
-
Gianella, S.1
Anderson, C.M.2
Vargas, M.V.3
-
70
-
-
84904664520
-
Cytomegalovirus replication in semen is associated with higher levels of proviral HIV DNA and CD4+ T cell activation during antiretroviral treatment
-
Gianella S, Massanella M, Richman DD, et al. Cytomegalovirus replication in semen is associated with higher levels of proviral HIV DNA and CD4+ T cell activation during antiretroviral treatment. J Virol 2014; 88: 7818-7827.
-
(2014)
J Virol
, vol.88
, pp. 7818-7827
-
-
Gianella, S.1
Massanella, M.2
Richman, D.D.3
-
71
-
-
79955028940
-
Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapy
-
Hunt PW, Martin JN, Sinclair E, et al. Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapy. J Infect Dis 2011; 203: 1474-1483.
-
(2011)
J Infect Dis
, vol.203
, pp. 1474-1483
-
-
Hunt, P.W.1
Martin, J.N.2
Sinclair, E.3
-
72
-
-
84904115855
-
Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
-
Maldarelli F, Wu X, Su L, et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science 2014; 345: 179-183.
-
(2014)
Science
, vol.345
, pp. 179-183
-
-
Maldarelli, F.1
Wu, X.2
Su, L.3
-
73
-
-
84905917318
-
HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection
-
Wagner TA, McLaughlin S, Garg K, et al. HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection. Science 2014; 345: 570-573.
-
(2014)
Science
, vol.345
, pp. 570-573
-
-
Wagner, T.A.1
McLaughlin, S.2
Garg, K.3
-
74
-
-
84922249841
-
HIV-1 integration landscape during latent and active infection
-
Cohn LB, Silva IT, Oliveira TY, et al. HIV-1 integration landscape during latent and active infection. Cell 2015; 160: 420-432.
-
(2015)
Cell
, vol.160
, pp. 420-432
-
-
Cohn, L.B.1
Silva, I.T.2
Oliveira, T.Y.3
-
75
-
-
84890847660
-
The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time
-
Josefsson L, Stockenstrom von S, Faria NR, et al. The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time. Proc Natl Acad Sci 2013; 110: E4987-E4996.
-
(2013)
Proc Natl Acad Sci
, vol.110
, pp. E4987-E4996
-
-
Josefsson, L.1
Von S, S.2
Faria, N.R.3
-
76
-
-
84939625364
-
Longitudinal genetic characterization reveals that cell proliferation maintains a persistent HIV type 1 DNA pool during effective HIV therapy
-
Stockenstrom von S, Odevall L, Lee E, et al. Longitudinal genetic characterization reveals that cell proliferation maintains a persistent HIV type 1 DNA pool during effective HIV therapy. J Infect Dis 2015; 212: 596-607.
-
(2015)
J Infect Dis
, vol.212
, pp. 596-607
-
-
Von S, S.1
Odevall, L.2
Lee, E.3
-
77
-
-
84937027268
-
Increased ex vivo cell death of central memory CD4 T cells in treated HIV infected individuals with unsatisfactory immune recovery
-
Massanella M, Gómez-Mora E, Carrillo J, et al. Increased ex vivo cell death of central memory CD4 T cells in treated HIV infected individuals with unsatisfactory immune recovery. J Translat Med 2015; 13: 141.
-
(2015)
J Translat Med
, vol.13
, pp. 141
-
-
Massanella, M.1
Gómez-Mora, E.2
Carrillo, J.3
-
78
-
-
67650458437
-
Responsiveness of T cells to interleukin-7 is associated with higher CD4+ T cell counts in HIV-1-positive individuals with highly active antiretroviral therapy-induced viral load suppression
-
Camargo JF, Kulkarni H, Agan BK, et al. Responsiveness of T cells to interleukin-7 is associated with higher CD4+ T cell counts in HIV-1-positive individuals with highly active antiretroviral therapy-induced viral load suppression. J Infect Dis 2009; 199: 1872-1882.
-
(2009)
J Infect Dis
, vol.199
, pp. 1872-1882
-
-
Camargo, J.F.1
Kulkarni, H.2
Agan, B.K.3
-
79
-
-
84879302206
-
Interleukin-7 promotes HIV persistence during antiretroviral therapy
-
Vandergeeten C, Fromentin R, DaFonseca S, et al. Interleukin-7 promotes HIV persistence during antiretroviral therapy. Blood 2013; 121: 4321-4329.
-
(2013)
Blood
, vol.121
, pp. 4321-4329
-
-
Vandergeeten, C.1
Fromentin, R.2
DaFonseca, S.3
-
80
-
-
84904176435
-
Programmed death-1 expression on CD4+ and CD8+ T cells in treated and untreated HIV disease
-
Cockerham LR, Jain V, Sinclair E, et al. Programmed death-1 expression on CD4+ and CD8+ T cells in treated and untreated HIV disease. AIDS (London, England) 2014; 28: 1749-1758.
-
(2014)
AIDS (London, England)
, vol.28
, pp. 1749-1758
-
-
Cockerham, L.R.1
Jain, V.2
Sinclair, E.3
-
81
-
-
58149191881
-
The common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands
-
Kinter AL, Godbout EJ, McNally JP, et al. The common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 induce the expression of programmed death-1 and its ligands. J Immunol 2008; 181: 6738-6746.
-
(2008)
J Immunol
, vol.181
, pp. 6738-6746
-
-
Kinter, A.L.1
Godbout, E.J.2
McNally, J.P.3
-
82
-
-
84973123958
-
The immune checkpoints PD-1 LAG-3 and TIGIT are biomarkers of HIV infected cells during ART and identify distinct cellular reservoirs
-
Sydney (Australia)
-
Fromentin R, Bakeman W, Lawani MB, et al. The immune checkpoints PD-1, LAG-3 and TIGIT are biomarkers of HIV infected cells during ART and identify distinct cellular reservoirs. In: Towards an HIV cure Preconference Symposium; 2014; Sydney (Australia).
-
(2014)
Towards An HIV Cure Preconference Symposium
-
-
Fromentin, R.1
Bakeman, W.2
Lawani, M.B.3
-
83
-
-
84926368278
-
Site-specific differences in T cell frequencies and phenotypes in the blood and gut of HIV-uninfected and ARTtreated HIV+ adults
-
Yukl SA, Shergill AK, Girling V, et al. Site-specific differences in T cell frequencies and phenotypes in the blood and gut of HIV-uninfected and ARTtreated HIV+ adults. Plos One 2015; 10: e0121290.
-
(2015)
Plos One
, vol.10
, pp. e0121290
-
-
Yukl, S.A.1
Shergill, A.K.2
Girling, V.3
-
84
-
-
33745813929
-
Expression of interleukin (IL)- 2 and IL-7 receptors discriminates between human regulatory and activated T cells
-
Seddiki N, Santner-Nanan B, Martinson J, et al. Expression of interleukin (IL)- 2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006; 203: 1693-1700.
-
(2006)
J Exp Med
, vol.203
, pp. 1693-1700
-
-
Seddiki, N.1
Santner-Nanan, B.2
Martinson, J.3
-
85
-
-
5644263642
-
Role of LAG-3 in regulatory T cells
-
Huang C-T, Workman CJ, Flies D, et al. Role of LAG-3 in regulatory T cells. Immunity 2004; 21: 503-513.
-
(2004)
Immunity
, vol.21
, pp. 503-513
-
-
Huang, C.-T.1
Workman, C.J.2
Flies, D.3
-
86
-
-
84899101494
-
Association between discordant immunological response to highly active antiretroviral therapy, regulatory T cell percentage, immune cell activation and very low-level viraemia in HIV-infected patients
-
Saison J, Ferry T, Demaret J, et al. Association between discordant immunological response to highly active antiretroviral therapy, regulatory T cell percentage, immune cell activation and very low-level viraemia in HIV-infected patients. Clin Exp Immunol 2014; 176: 401-409.
-
(2014)
Clin Exp Immunol
, vol.176
, pp. 401-409
-
-
Saison, J.1
Ferry, T.2
Demaret, J.3
-
87
-
-
53249137958
-
Resting regulatory CD4 T cells: A site of HIV persistence in patients on long-term effective antiretroviral therapy
-
Tran T-A, de Goë R de Herve M-G, Hendel-Chavez H, et al. Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy. Plos One 2008; 3: e3305.
-
(2008)
Plos One
, vol.3
, pp. e3305
-
-
Tran, T.-A.1
De Goë, R.2
De Herve, M.-G.3
Hendel-Chavez, H.4
-
88
-
-
84938849577
-
Interleukin-37 expression is increased in chronic HIV-1-infected individuals and is associated with inflammation and the size of the total viral reservoir
-
Højen JF, Rasmussen TA, Andersen KLD, et al. Interleukin-37 expression is increased in chronic HIV-1-infected individuals and is associated with inflammation and the size of the total viral reservoir. Mol Med 2015; 21: 337-345.
-
(2015)
Mol Med
, vol.21
, pp. 337-345
-
-
Højen, J.F.1
Rasmussen, T.A.2
Kld, A.3
-
89
-
-
78149441721
-
Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection
-
Schmid A, Gianella S, Wyl von V, et al. Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection. Plos One 2010; 5: e13310.
-
(2010)
Plos One
, vol.5
, pp. e13310
-
-
Schmid, A.1
Gianella, S.2
Von, W.3
-
90
-
-
49049107011
-
Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA
-
Pasternak AO, Adema KW, Bakker M, et al. Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA. J Clin Microbiol 2008; 46: 2206-2211.
-
(2008)
J Clin Microbiol
, vol.46
, pp. 2206-2211
-
-
Pasternak, A.O.1
Adema, K.W.2
Bakker, M.3
-
91
-
-
84881319698
-
Gag-positive reservoir cells are susceptible to HIV-specific cytotoxic T lymphocyte mediated clearance in vitro and can be detected in vivo [corrected]
-
Graf EH, Pace MJ, Peterson BA, et al. Gag-positive reservoir cells are susceptible to HIV-specific cytotoxic T lymphocyte mediated clearance in vitro and can be detected in vivo [corrected]. Plos One 2013; 8: e71879.
-
(2013)
Plos One
, vol.8
, pp. e71879
-
-
Graf, E.H.1
Pace, M.J.2
Peterson, B.A.3
-
92
-
-
84940853263
-
The Tat inhibitor didehydrocortistatin A prevents HIV-1 reactivation from latency
-
Mousseau G, Kessing CF, Fromentin R, et al. The Tat inhibitor didehydrocortistatin A prevents HIV-1 reactivation from latency. Bio 2015; 6: e00465.
-
(2015)
Bio
, vol.6
, pp. e00465
-
-
Mousseau, G.1
Kessing, C.F.2
Fromentin, R.3
-
93
-
-
84892372311
-
Can early therapy reduce inflammation?
-
Sandler NG, Sereti I. Can early therapy reduce inflammation? Curr Opin HIV AIDS 2014; 9: 72-79.
-
(2014)
Curr Opin HIV AIDS
, vol.9
, pp. 72-79
-
-
Sandler, N.G.1
Sereti, I.2
-
94
-
-
84899449343
-
Reduction of HIV persistence following transplantation in HIV-infected kidney transplant recipients
-
for Solid Organ Transplantation in HIV Study Investigators
-
Stock PG, Barin B, Hatano H, et al., for Solid Organ Transplantation in HIV Study Investigators. Reduction of HIV persistence following transplantation in HIV-infected kidney transplant recipients. Am J Transplant 2014; 14: 1136-1141.
-
(2014)
Am J Transplant
, vol.14
, pp. 1136-1141
-
-
Stock, P.G.1
Barin, B.2
Hatano, H.3
-
95
-
-
77950936860
-
The virologic and immunologic effects of cyclosporine as an adjunct to antiretroviral therapy in patients treated during acute and early HIV-1 infection
-
Markowitz M, Vaida F, Hare CB, et al. The virologic and immunologic effects of cyclosporine as an adjunct to antiretroviral therapy in patients treated during acute and early HIV-1 infection. J Infect Dis 2010; 201: 1298-1302.
-
(2010)
J Infect Dis
, vol.201
, pp. 1298-1302
-
-
Markowitz, M.1
Vaida, F.2
Hare, C.B.3
-
96
-
-
84896917340
-
Ruxolitinib and tofacitinib are potent and selective inhibitors of HIV-1 replication and virus reactivation in vitro
-
Gavegnano C, Detorio M, Montero C, et al. Ruxolitinib and tofacitinib are potent and selective inhibitors of HIV-1 replication and virus reactivation in vitro. Antimicrob Agents Chemother 2014; 58: 1977-1986.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 1977-1986
-
-
Gavegnano, C.1
Detorio, M.2
Montero, C.3
-
97
-
-
84942154611
-
Innate immune activity correlates with CD4 T cell-associated HIV-1 DNA decline during latency-reversing treatment with panobinostat
-
Olesen R, Vigano S, Rasmussen TA, et al. Innate immune activity correlates with CD4 T cell-associated HIV-1 DNA decline during latency-reversing treatment with panobinostat. J Virol 2015; 89: 10176-10189.
-
(2015)
J Virol
, vol.89
, pp. 10176-10189
-
-
Olesen, R.1
Vigano, S.2
Rasmussen, T.A.3
-
98
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, Kluger H, Callahan MK, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med 2013; 369: 122-133.
-
(2013)
N Engl J Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
-
99
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012; 366: 2443-2454.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
100
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363: 711-723.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
101
-
-
84863337769
-
Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation
-
Shan L, Deng K, Shroff NS, et al. Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation. Immunity 2012; 36: 491-501.
-
(2012)
Immunity
, vol.36
, pp. 491-501
-
-
Shan, L.1
Deng, K.2
Shroff, N.S.3
-
102
-
-
84922279077
-
Effect of ipilimumab on the HIV reservoir in an HIV-infected individual with metastatic melanoma
-
Wightman F, Solomon A, Kumar SS, et al. Effect of ipilimumab on the HIV reservoir in an HIV-infected individual with metastatic melanoma. AIDS (London, England) 2015; 29: 504-506.
-
(2015)
AIDS (London, England)
, vol.29
, pp. 504-506
-
-
Wightman, F.1
Solomon, A.2
Kumar, S.S.3
|