Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 10, 2015, Pages E1126-E1134

  Rothenberger, Meghan K ^a   Keele, Brandon F ^b   Wietgrefe, Stephen W ^a   Fletcher, Courtney V ^c   Beilman, Gregory J ^d   Chipman, Jeffrey G ^e   Khoruts, Alexander ^a   Estes, Jacob D ^b   Anderson, Jodi ^a   Callisto, Samuel P ^a   Schmidt, Thomas E ^a   Thorkelson, Ann ^a   Reilly, Cavan ^e   Perkey, Katherine ^a   Reimann, Thomas G ^a   Utay, Netanya S ^f   Makamdop, Krystelle Nganou ^g   Stevenson, Mario ^h   Douek, Daniel C ^g   Haase, Ashley T ^a   Schacker, Timothy W ^a   more..

^a UNIVERSITY OF MINNESOTA   (United States)

^b FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^d UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF MINNESOTA   (United States)

^f University of Texas Medical Branch School of Medicine   (United States)

^g NATIONAL INSTITUTES OF HEALTH   (United States)

^h UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Founder population; HIV AIDS; Treatment interruption; Viral recrudescence

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ATAZANAVIR; EFAVIRENZ; RITONAVIR; VIRUS RNA;

ADULT; ANTIVIRAL THERAPY; ARTICLE; CD4 LYMPHOCYTE COUNT; CLINICAL ARTICLE; DNA SEQUENCE; DNA VIRUS; FEMALE; GENE AMPLIFICATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IN SITU HYBRIDIZATION; INTESTINE LYMPHATIC TISSUE; LYMPH NODE; LYMPHOID TISSUE; MALE; MIDDLE AGED; MONONUCLEAR CELL; PRIORITY JOURNAL; RECTUM BIOPSY; RNA SEQUENCE; VIRUS ISOLATION; VIRUS LOAD; BLOOD; DRUG ADMINISTRATION; GENETICS; HIV INFECTIONS; MOLECULAR GENETICS; PHYLOGENY; PHYSIOLOGY; VIROLOGY;

ADULT; ANTI-HIV AGENTS; CD4 LYMPHOCYTE COUNT; DRUG ADMINISTRATION SCHEDULE; HIV; HIV INFECTIONS; HUMANS; IN SITU HYBRIDIZATION; LYMPHOID TISSUE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PHYLOGENY; RNA, VIRAL; VIRAL LOAD;

EID: 84924365877     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1414926112     Document Type: Article

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