-
1
-
-
0028792184
-
In vivo fate of HIV-1-infected T cells: Quantitative analysis of the transition to stable latency
-
Chun TW, Finzi D, Margolick J, Chadwick K, Schwartz D, Siliciano RF. 1995. In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency. Nat Med 1:1284–1290. http://dx.doi.org/10.1038/nm1295-1284
-
(1995)
Nat Med
, vol.1
, pp. 1284-1290
-
-
Chun, T.W.1
Finzi, D.2
Margolick, J.3
Chadwick, K.4
Schwartz, D.5
Siliciano, R.F.6
-
2
-
-
0030659177
-
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
-
Chun TW, Stuyver L, Mizell SB, Ehler LA, Mican JA, Baseler M, Lloyd AL, Nowak MA, Fauci AS. 1997. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy. Proc Natl Acad Sci U S A 94:13193–13197. http://dx.doi.org/10.1073/pnas.94.24.13193
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13193-13197
-
-
Chun, T.W.1
Stuyver, L.2
Mizell, S.B.3
Ehler, L.A.4
Mican, J.A.5
Baseler, M.6
Lloyd, A.L.7
Nowak, M.A.8
Fauci, A.S.9
-
3
-
-
14444273439
-
Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
-
Finzi D, Hermankova M, Pierson T, Carruth LM, Buck C, Chaisson RE, Quinn TC, Chadwick K, Margolick J, Brookmeyer R, Gallant J, Markowitz M, Ho DD, Richman DD, Siliciano RF. 1997. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 278: 1295–1300. http://dx.doi.org/10.1126/science.278.5341.1295
-
(1997)
Science
, vol.278
, pp. 1295-1300
-
-
Finzi, D.1
Hermankova, M.2
Pierson, T.3
Carruth, L.M.4
Buck, C.5
Chaisson, R.E.6
Quinn, T.C.7
Chadwick, K.8
Margolick, J.9
Brookmeyer, R.10
Gallant, J.11
Markowitz, M.12
Ho, D.D.13
Richman, D.D.14
Siliciano, R.F.15
-
4
-
-
0030712305
-
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
-
Wong JK, Hezareh M, Günthard HF, Havlir DV, Ignacio CC, Spina CA, Richman DD. 1997. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science 278:1291–1295. http://dx.doi.org/10.1126/science.278.5341.1291
-
(1997)
Science
, vol.278
, pp. 1291-1295
-
-
Wong, J.K.1
Hezareh, M.2
Günthard, H.F.3
Havlir, D.V.4
Ignacio, C.C.5
Spina, C.A.6
Richman, D.D.7
-
5
-
-
0032953920
-
Latent infection of CD4+T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
-
Finzi D, Blankson J, Siliciano JD, Margolick JB, Chadwick K, Pierson T, Smith K, Lisziewicz J, Lori F, Flexner C, Quinn TC, Chaisson RE, Rosenberg E, Walker B, Gange S, Gallant J, Siliciano RF. 1999. Latent infection of CD4+T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat Med 5:512–517. http://dx.doi.org/10.1038/8394
-
(1999)
Nat Med
, vol.5
, pp. 512-517
-
-
Finzi, D.1
Blankson, J.2
Siliciano, J.D.3
Margolick, J.B.4
Chadwick, K.5
Pierson, T.6
Smith, K.7
Lisziewicz, J.8
Lori, F.9
Flexner, C.10
Quinn, T.C.11
Chaisson, R.E.12
Rosenberg, E.13
Walker, B.14
Gange, S.15
Gallant, J.16
Siliciano, R.F.17
-
6
-
-
0038579210
-
Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
-
Siliciano JD, Kajdas J, Finzi D, Quinn TC, Chadwick K, Margolick JB, Kovacs C, Gange SJ, Siliciano RF. 2003. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat Med 9:727–728. http://dx.doi.org/10.1038/nm880
-
(2003)
Nat Med
, vol.9
, pp. 727-728
-
-
Siliciano, J.D.1
Kajdas, J.2
Finzi, D.3
Quinn, T.C.4
Chadwick, K.5
Margolick, J.B.6
Kovacs, C.7
Gange, S.J.8
Siliciano, R.F.9
-
7
-
-
77950537810
-
HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAARTsuppressed subjects
-
Buzón MJ, Massanella M, Llibre JM, Esteve A, Dahl V, Puertas MC, Gatell JM, Domingo P, Paredes R, Sharkey M, Palmer S, Stevenson M, Clotet B, Blanco J, Martinez-Picado J. 2010. HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAARTsuppressed subjects. Nat Med 16:460–465. http://dx.doi.org/10.1038/nm.2111
-
(2010)
Nat Med
, vol.16
, pp. 460-465
-
-
Buzón, M.J.1
Massanella, M.2
Llibre, J.M.3
Esteve, A.4
Dahl, V.5
Puertas, M.C.6
Gatell, J.M.7
Domingo, P.8
Paredes, R.9
Sharkey, M.10
Palmer, S.11
Stevenson, M.12
Clotet, B.13
Blanco, J.14
Martinez-Picado, J.15
-
8
-
-
84893830170
-
Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues
-
Fletcher CV, Staskus K, Wietgrefe SW, Rothenberger M, Reilly C, Chipman JG, Beilman GJ, Khoruts A, Thorkelson A, Schmidt TE, Anderson J, Perkey K, Stevenson M, Perelson AS, Douek DC, Haase AT, Schacker TW. 2014. Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues. Proc Natl Acad Sci U S A 111: 2307–2312. http://dx.doi.org/10.1073/pnas.1318249111
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 2307-2312
-
-
Fletcher, C.V.1
Staskus, K.2
Wietgrefe, S.W.3
Rothenberger, M.4
Reilly, C.5
Chipman, J.G.6
Beilman, G.J.7
Khoruts, A.8
Thorkelson, A.9
Schmidt, T.E.10
Erson, J.11
Perkey, K.12
Stevenson, M.13
Perelson, A.S.14
Douek, D.C.15
Haase, A.T.16
Schacker, T.W.17
-
9
-
-
84885411247
-
Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: A randomized, placebo-controlled trial
-
Hatano H, Strain MC, Scherzer R, Bacchetti P, Wentworth D, Hoh R, Martin JN, McCune JM, Neaton JD, Tracy RP, Hsue PY, Richman DD, Deeks SG. 2013. Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: a randomized, placebo-controlled trial. J Infect Dis 208: 1436–1442. http://dx.doi.org/10.1093/infdis/jit453
-
(2013)
J Infect Dis
, vol.208
, pp. 1436-1442
-
-
Hatano, H.1
Strain, M.C.2
Scherzer, R.3
Bacchetti, P.4
Wentworth, D.5
Hoh, R.6
Martin, J.N.7
McCune, J.M.8
Neaton, J.D.9
Tracy, R.P.10
Hsue, P.Y.11
Richman, D.D.12
Deeks, S.G.13
-
10
-
-
84855909205
-
Short-course raltegravir intensification does not increase 2 long terminal repeat episomal HIV-1 DNA in patients on effective antiretroviral therapy
-
Besson GJ, McMahon D, Maldarelli F, Mellors JW. 2012. Short-course raltegravir intensification does not increase 2 long terminal repeat episomal HIV-1 DNA in patients on effective antiretroviral therapy. Clin Infect Dis 54:451–453. http://dx.doi.org/10.1093/cid/cir721
-
(2012)
Clin Infect Dis
, vol.54
, pp. 451-453
-
-
Besson, G.J.1
McMahon, D.2
Maldarelli, F.3
Mellors, J.W.4
-
11
-
-
84897437605
-
Lack of detectable HIV-1 molecular evolution during suppressive antiretroviral therapy
-
Kearney MF, Spindler J, Shao W, Yu S, Anderson EM, O’Shea A, Rehm C, Poethke C, Kovacs N, Mellors JW, Coffin JM, Maldarelli F. 2014. Lack of detectable HIV-1 molecular evolution during suppressive antiretroviral therapy. PLoS Pathog 10:e1004010. http://dx.doi.org/10.1371/journal.ppat.1004010
-
(2014)
Plos Pathog
, vol.10
-
-
Kearney, M.F.1
Spindler, J.2
Shao, W.3
Yu, S.4
Erson, E.M.5
O’Shea, A.6
Rehm, C.7
Poethke, C.8
Kovacs, N.9
Mellors, J.W.10
Coffin, J.M.11
Maldarelli, F.12
-
12
-
-
84886790685
-
The end of AIDS: HIV infection as a chronic disease
-
Deeks SG, Lewin SR, Havlir DV. 2013. The end of AIDS: HIV infection as a chronic disease. Lancet 382:1525–1533. http://dx.doi.org/10.1016/S0140-6736(13)61809-7
-
(2013)
Lancet
, vol.382
, pp. 1525-1533
-
-
Deeks, S.G.1
Lewin, S.R.2
Havlir, D.V.3
-
13
-
-
67249121143
-
Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy
-
Dinoso JB, Kim SY, Wiegand AM, Palmer SE, Gange SJ, Cranmer L, O’Shea A, Callender M, Spivak A, Brennan T, Kearney MF, Proschan MA, Mican JM, Rehm CA, Coffin JM, Mellors JW, Siliciano RF, Maldarelli F. 2009. Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy. Proc Natl Acad Sci U S A 106:9403–9408. http://dx.doi.org/10.1073/pnas.0903107106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9403-9408
-
-
Dinoso, J.B.1
Kim, S.Y.2
Wiegand, A.M.3
Palmer, S.E.4
Gange, S.J.5
Cranmer, L.6
O’Shea, A.7
Callender, M.8
Spivak, A.9
Brennan, T.10
Kearney, M.F.11
Proschan, M.A.12
Mican, J.M.13
Rehm, C.A.14
Coffin, J.M.15
Mellors, J.W.16
Siliciano, R.F.17
Maldarelli, F.18
-
14
-
-
77956856393
-
The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: A randomized controlled trial
-
Gandhi RT, Zheng L, Bosch RJ, Chan ES, Margolis DM, Read S, Kallungal B, Palmer S, Medvik K, Lederman MM, Alatrakchi N, Jacobson JM, Wiegand A, Kearney M, Coffin JM, Mellors JW, Eron JJ, AIDS Clinical Trials Group A5244 Team. 2010. The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial. PLoS Med 7:e1000321. http://dx.doi.org/10.1371/journal.pmed.1000321
-
(2010)
Plos Med
, vol.7
-
-
Gandhi, R.T.1
Zheng, L.2
Bosch, R.J.3
Chan, E.S.4
Margolis, D.M.5
Read, S.6
Kallungal, B.7
Palmer, S.8
Medvik, K.9
Lederman, M.M.10
Alatrakchi, N.11
Jacobson, J.M.12
Wiegand, A.13
Kearney, M.14
Coffin, J.M.15
Mellors, J.W.16
Eron, J.J.17
-
15
-
-
0023005780
-
Demonstration of virus-specific transcriptional activator(S) in cells infected with HTLV-III by an in vitro cell-free system
-
Okamoto T, Wong-Staal F. 1986. Demonstration of virus-specific transcriptional activator(s) in cells infected with HTLV-III by an in vitro cell-free system. Cell 47:29–35. http://dx.doi.org/10.1016/0092-8674(86)90363-6
-
(1986)
Cell
, vol.47
, pp. 29-35
-
-
Okamoto, T.1
Wong-Staal, F.2
-
16
-
-
0024651195
-
Structure, sequence, and position of the stem-loop in TAR determine transcriptional elongation by tat through the HIV-1 long terminal repeat
-
Selby MJ, Bain ES, Luciw PA, Peterlin BM. 1989. Structure, sequence, and position of the stem-loop in TAR determine transcriptional elongation by tat through the HIV-1 long terminal repeat. Genes Dev 3:547–558. http://dx.doi.org/10.1101/gad.3.4.547
-
(1989)
Genes Dev
, vol.3
, pp. 547-558
-
-
Selby, M.J.1
Bain, E.S.2
Luciw, P.A.3
Peterlin, B.M.4
-
17
-
-
0024414213
-
HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation
-
Laspia MF, Rice AP, Mathews MB. 1989. HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation. Cell 59:283–292. http://dx.doi.org/10.1016/0092-8674(89)90290-0
-
(1989)
Cell
, vol.59
, pp. 283-292
-
-
Laspia, M.F.1
Rice, A.P.2
Mathews, M.B.3
-
18
-
-
14444281157
-
P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro
-
Mancebo HS, Lee G, Flygare J, Tomassini J, Luu P, Zhu Y, Peng J, Blau C, Hazuda D, Price D, Flores O. 1997. P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro. Genes Dev 11: 2633–2644. http://dx.doi.org/10.1101/gad.11.20.2633
-
(1997)
Genes Dev
, vol.11
, pp. 2633-2644
-
-
Mancebo, H.S.1
Lee, G.2
Flygare, J.3
Tomassini, J.4
Luu, P.5
Zhu, Y.6
Peng, J.7
Blau, C.8
Hazuda, D.9
Price, D.10
Flores, O.11
-
19
-
-
0032548918
-
A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA
-
Wei P, Garber ME, Fang SM, Fischer WH, Jones KA. 1998. A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell 92: 451–462. http://dx.doi.org/10.1016/S0092-8674(00)80939-3
-
(1998)
Cell
, vol.92
, pp. 451-462
-
-
Wei, P.1
Garber, M.E.2
Fang, S.M.3
Fischer, W.H.4
Jones, K.A.5
-
20
-
-
79954441735
-
The molecular biology of HIV latency: Breaking and restoring the Tat-dependent transcriptional circuit
-
Karn J. 2011. The molecular biology of HIV latency: breaking and restoring the Tat-dependent transcriptional circuit. Curr Opin HIV AIDS 6:4–11. http://dx.doi.org/10.1097/COH.0b013e328340ffbb
-
(2011)
Curr Opin HIV AIDS
, vol.6
, pp. 4-11
-
-
Karn, J.1
-
21
-
-
81755180766
-
The control of HIV transcription: Keeping RNA polymerase II on track
-
Ott M, Geyer M, Zhou Q. 2011. The control of HIV transcription: keeping RNA polymerase II on track. Cell Host Microbe 10:426–435. http://dx.doi.org/10.1016/j.chom.2011.11.002
-
(2011)
Cell Host Microbe
, vol.10
, pp. 426-435
-
-
Ott, M.1
Geyer, M.2
Zhou, Q.3
-
22
-
-
0035158637
-
Induction of TAK (Cyclin T1/P-TEFb) in purified resting CD4(_) T lymphocytes by combination of cytokines
-
Ghose R, Liou LY, Herrmann CH, Rice AP. 2001. Induction of TAK (cyclin T1/P-TEFb) in purified resting CD4(_) T lymphocytes by combination of cytokines. J Virol 75:11336–11343. http://dx.doi.org/10.1128/JVI.75.23.11336-11343.2001
-
(2001)
J Virol
, vol.75
, pp. 11336-11343
-
-
Ghose, R.1
Liou, L.Y.2
Herrmann, C.H.3
Rice, A.P.4
-
23
-
-
0032567042
-
Host control of HIV-1 parasitism in T cells by the nuclear factor of activated T cells
-
Kinoshita S, Chen BK, Kaneshima H, Nolan GP. 1998. Host control of HIV-1 parasitism in T cells by the nuclear factor of activated T cells. Cell 95:595–604. http://dx.doi.org/10.1016/S0092-8674(00)81630-X
-
(1998)
Cell
, vol.95
, pp. 595-604
-
-
Kinoshita, S.1
Chen, B.K.2
Kaneshima, H.3
Nolan, G.P.4
-
24
-
-
0023176085
-
An inducible transcription factor activates expression of human immunodeficiency virus in T cells
-
Nabel G, Baltimore D. 1987. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 326: 711–713. http://dx.doi.org/10.1038/326711a0
-
(1987)
Nature
, vol.326
, pp. 711-713
-
-
Nabel, G.1
Baltimore, D.2
-
25
-
-
37149031062
-
CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency
-
Tyagi M, Karn J. 2007. CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency. EMBO J 26:4985–4995. http://dx.doi.org/10.1038/sj.emboj.7601928
-
(2007)
EMBO J
, vol.26
, pp. 4985-4995
-
-
Tyagi, M.1
Karn, J.2
-
26
-
-
0036232430
-
Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat
-
He G, Margolis DM. 2002. Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat. Mol Cell Biol 22:2965–2973. http://dx.doi.org/10.1128/MCB.22.9.2965-2973.2002
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2965-2973
-
-
He, G.1
Margolis, D.M.2
-
27
-
-
84869170593
-
SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells
-
Baldauf HM, Pan X, Erikson E, Schmidt S, Daddacha W, Burggraf M, Schenkova K, Ambiel I, Wabnitz G, Gramberg T, Panitz S, Flory E, Landau NR, Sertel S, Rutsch F, Lasitschka F, Kim B, König R, Fackler OT, Keppler OT. 2012. SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells. Nat Med 18:1682–1687. http://dx.doi.org/10.1038/nm.2964
-
(2012)
Nat Med
, vol.18
, pp. 1682-1687
-
-
Baldauf, H.M.1
Pan, X.2
Erikson, E.3
Schmidt, S.4
Daddacha, W.5
Burggraf, M.6
Schenkova, K.7
Ambiel, I.8
Wabnitz, G.9
Gramberg, T.10
Panitz, S.11
Flory, E.12
Landau, N.R.13
Sertel, S.14
Rutsch, F.15
Lasitschka, F.16
Kim, B.17
König, R.18
Fackler, O.T.19
Keppler, O.T.20
more..
-
28
-
-
0027377963
-
Low levels of deoxynucleotides in peripheral blood lymphocytes: A strategy to inhibit human immunode- ficiency virus type 1 replication
-
Gao WY, Cara A, Gallo RC, Lori F. 1993. Low levels of deoxynucleotides in peripheral blood lymphocytes: a strategy to inhibit human immunode- ficiency virus type 1 replication. Proc Natl Acad Sci U S A 90:8925–8928. http://dx.doi.org/10.1073/pnas.90.19.8925
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 8925-8928
-
-
Gao, W.Y.1
Cara, A.2
Gallo, R.C.3
Lori, F.4
-
29
-
-
48649089113
-
Transcriptional interference antagonizes proviral gene expression to promote HIV latency
-
Lenasi T, Contreras X, Peterlin BM. 2008. Transcriptional interference antagonizes proviral gene expression to promote HIV latency. Cell Host Microbe 4:123–133. http://dx.doi.org/10.1016/j.chom.2008.05.016
-
(2008)
Cell Host Microbe
, vol.4
, pp. 123-133
-
-
Lenasi, T.1
Contreras, X.2
Peterlin, B.M.3
-
30
-
-
0034566127
-
Role of chromatin in HIV-1 transcriptional regulation
-
Van Lint C. 2000. Role of chromatin in HIV-1 transcriptional regulation. Adv Pharmacol 48:121–160. http://dx.doi.org/10.1016/S1054-3589(00)48005-1
-
(2000)
Adv Pharmacol
, vol.48
, pp. 121-160
-
-
Van Lint, C.1
-
31
-
-
0029919356
-
Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation
-
Van Lint C, Emiliani S, Ott M, Verdin E. 1996. Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. EMBO J 15:1112–1120
-
(1996)
EMBO J
, vol.15
, pp. 1112-1120
-
-
Van Lint, C.1
Emiliani, S.2
Ott, M.3
Verdin, E.4
-
32
-
-
84925604110
-
Regulation of HIV-1 latency by chromatin structure and nuclear architecture
-
Lusic M, Giacca M. 2015. Regulation of HIV-1 latency by chromatin structure and nuclear architecture. J Mol Biol 427:688–694. http://dx.doi.org/10.1016/j.jmb.2014.07.022
-
(2015)
J Mol Biol
, vol.427
, pp. 688-694
-
-
Lusic, M.1
Giacca, M.2
-
33
-
-
70049090006
-
CpG methylation controls reactivation of HIV from latency
-
Blazkova J, Trejbalova K, Gondois-Rey F, Halfon P, Philibert P, Guiguen A, Verdin E, Olive D, Van Lint C, Hejnar J, Hirsch I. 2009. CpG methylation controls reactivation of HIV from latency. PLoS Pathog 5:e1000554. http://dx.doi.org/10.1371/journal.ppat.1000554
-
(2009)
Plos Pathog
, vol.5
-
-
Blazkova, J.1
Trejbalova, K.2
Gondois-Rey, F.3
Halfon, P.4
Philibert, P.5
Guiguen, A.6
Verdin, E.7
Olive, D.8
Van Lint, C.9
Hejnar, J.10
Hirsch, I.11
-
34
-
-
84861314042
-
Paucity of HIV DNA methylation in latently infected, resting CD4+T cells from infected individuals receiving antiretroviral therapy
-
Blazkova J, Murray D, Justement JS, Funk EK, Nelson AK, Moir S, Chun TW, Fauci AS. 2012. Paucity of HIV DNA methylation in latently infected, resting CD4+T cells from infected individuals receiving antiretroviral therapy. J Virol 86:5390–5392. http://dx.doi.org/10.1128/JVI.00040-12
-
(2012)
J Virol
, vol.86
, pp. 5390-5392
-
-
Blazkova, J.1
Murray, D.2
Justement, J.S.3
Funk, E.K.4
Nelson, A.K.5
Moir, S.6
Chun, T.W.7
Fauci, A.S.8
-
35
-
-
84886769508
-
Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure
-
Ho Y-C, Shan L, Hosmane NN, Wang J, Laskey SB, Rosenbloom DI, Lai J, Blankson JN, Siliciano JD, Siliciano RF. 2013. Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure. Cell 155:540–551. http://dx.doi.org/10.1016/j.cell.2013.09.020
-
(2013)
Cell
, vol.155
, pp. 540-551
-
-
Ho, Y.-C.1
Shan, L.2
Hosmane, N.N.3
Wang, J.4
Laskey, S.B.5
Rosenbloom, D.I.6
Lai, J.7
Blankson, J.N.8
Siliciano, J.D.9
Siliciano, R.F.10
-
36
-
-
33746021681
-
The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter
-
Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E. 2006. The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter. J Biol Chem 281: 19960–19968. http://dx.doi.org/10.1074/jbc.M603336200
-
(2006)
J Biol Chem
, vol.281
, pp. 19960-19968
-
-
Mahmoudi, T.1
Parra, M.2
Vries, R.G.3
Kauder, S.E.4
Verrijzer, C.P.5
Ott, M.6
Verdin, E.7
-
37
-
-
33646130853
-
Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter
-
Tréand C, du Chéné I, Brès V, Kiernan R, Benarous R, Benkirane M, Emiliani S. 2006. Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter. EMBO J 25: 1690–1699. http://dx.doi.org/10.1038/sj.emboj.7601074
-
(2006)
EMBO J
, vol.25
, pp. 1690-1699
-
-
Tréand, C.1
Du Chéné, I.2
Brès, V.3
Kiernan, R.4
Benarous, R.5
Benkirane, M.6
Emiliani, S.7
-
38
-
-
0030914691
-
CREB-binding protein/p300 are transcriptional coactivators of p65
-
Gerritsen ME, Williams AJ, Neish AS, Moore S, Shi Y, Collins T. 1997. CREB-binding protein/p300 are transcriptional coactivators of p65. Proc Natl Acad Sci U S A 94:2927–2932. http://dx.doi.org/10.1073/pnas.94.7.2927
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 2927-2932
-
-
Gerritsen, M.E.1
Williams, A.J.2
Neish, A.S.3
Moore, S.4
Shi, Y.5
Collins, T.6
-
39
-
-
33748159867
-
Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription
-
Agbottah E, Deng L, Dannenberg LO, Pumfery A, Kashanchi F. 2006. Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription. Retrovirology 3:48. http://dx.doi.org/10.1186/1742-4690-3-48
-
(2006)
Retrovirology
, vol.3
-
-
Agbottah, E.1
Deng, L.2
Dannenberg, L.O.3
Pumfery, A.4
Kashanchi, F.5
-
40
-
-
0032544559
-
Activation of integrated provirus requires histone acetyltransferase. P300 and P/CAF are coactivators for HIV-1 Tat
-
Benkirane M, Chun RF, Xiao H, Ogryzko VV, Howard BH, Nakatani Y, Jeang KT. 1998. Activation of integrated provirus requires histone acetyltransferase. p300 and P/CAF are coactivators for HIV-1 Tat. J Biol Chem 273:24898–24905. http://dx.doi.org/10.1074/jbc.273.38.24898
-
(1998)
J Biol Chem
, vol.273
, pp. 24898-24905
-
-
Benkirane, M.1
Chun, R.F.2
Xiao, H.3
Ogryzko, V.V.4
Howard, B.H.5
Nakatani, Y.6
Jeang, K.T.7
-
41
-
-
0035958946
-
The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat
-
Col E, Caron C, Seigneurin-Berny D, Gracia J, Favier A, Khochbin S. 2001. The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat. J Biol Chem 276:28179–28184. http://dx.doi.org/10.1074/jbc.M101385200
-
(2001)
J Biol Chem
, vol.276
, pp. 28179-28184
-
-
Col, E.1
Caron, C.2
Seigneurin-Berny, D.3
Gracia, J.4
Favier, A.5
Khochbin, S.6
-
42
-
-
0031690395
-
Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein
-
Hottiger MO, Nabel GJ. 1998. Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein. J Virol 72:8252–8256
-
(1998)
J Virol
, vol.72
, pp. 8252-8256
-
-
Hottiger, M.O.1
Nabel, G.J.2
-
43
-
-
0032506242
-
HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter
-
Marzio G, Tyagi M, Gutierrez MI, Giacca M. 1998. HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter. Proc Natl Acad Sci U S A 95:13519–13524. http://dx.doi.org/10.1073/pnas.95.23.13519
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13519-13524
-
-
Marzio, G.1
Tyagi, M.2
Gutierrez, M.I.3
Giacca, M.4
-
44
-
-
0032775261
-
Human immunodeficiency virus type 1 tat protein activates transcription factor NF-kB through the cellular interferon-inducible, double-stranded RNA-dependent protein kinase, PKR
-
Demarchi F, Gutierrez MI, Giacca M. 1999. Human immunodeficiency virus type 1 tat protein activates transcription factor NF-kB through the cellular interferon-inducible, double-stranded RNA-dependent protein kinase, PKR. J Virol 73:7080–7086
-
(1999)
J Virol
, vol.73
, pp. 7080-7086
-
-
Demarchi, F.1
Gutierrez, M.I.2
Giacca, M.3
-
45
-
-
84923354567
-
A hardwired HIV latency program
-
Razooky BS, Pai A, Aull K, Rouzine IM, Weinberger LS. 2015. A hardwired HIV latency program. Cell 160:990–1001. http://dx.doi.org/10.1016/j.cell.2015.02.009
-
(2015)
Cell
, vol.160
, pp. 990-1001
-
-
Razooky, B.S.1
Pai, A.2
Aull, K.3
Rouzine, I.M.4
Weinberger, L.S.5
-
46
-
-
63549121736
-
Latently infected CD4+ T cells are enriched for HIV-1 Tat variants with impaired transactivation activity
-
Yukl S, Pillai S, Li P, Chang K, Pasutti W, Ahlgren C, Havlir D, Strain M, Günthard H, Richman D, Rice AP, Daar E, Little S, Wong JK. 2009. Latently infected CD4+ T cells are enriched for HIV-1 Tat variants with impaired transactivation activity. Virology 387:98–108. http://dx.doi.org/10.1016/j.virol.2009.01.013
-
(2009)
Virology
, vol.387
, pp. 98-108
-
-
Yukl, S.1
Pillai, S.2
Li, P.3
Chang, K.4
Pasutti, W.5
Ahlgren, C.6
Havlir, D.7
Strain, M.8
Günthard, H.9
Richman, D.10
Rice, A.P.11
Daar, E.12
Little, S.13
Wong, J.K.14
-
47
-
-
84928736772
-
Targeting HIV transcription: The quest for a functional cure
-
Mousseau G, Mediouni S, Valente ST. 2015. Targeting HIV transcription: the quest for a functional cure. Curr Top Microbiol Immunol 389:121–145 http://dx.doi.org/10.1007/82_2015_435
-
(2015)
Curr Top Microbiol Immunol
, vol.389
, pp. 121-145
-
-
Mousseau, G.1
Mediouni, S.2
Valente, S.T.3
-
48
-
-
84866295080
-
An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tatdependent HIV transcription
-
Mousseau G, Clementz MA, Bakeman WN, Nagarsheth N, Cameron M, Shi J, Baran P, Fromentin R, Chomont N, Valente ST. 2012. An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tatdependent HIV transcription. Cell Host Microbe 12:97–108. http://dx.doi.org/10.1016/j.chom.2012.05.016
-
(2012)
Cell Host Microbe
, vol.12
, pp. 97-108
-
-
Mousseau, G.1
Clementz, M.A.2
Bakeman, W.N.3
Nagarsheth, N.4
Cameron, M.5
Shi, J.6
Baran, P.7
Fromentin, R.8
Chomont, N.9
Valente, S.T.10
-
49
-
-
49049107011
-
Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA
-
Pasternak AO, Adema KW, Bakker M, Jurriaans S, Berkhout B, Cornelissen M, Lukashov VV. 2008. Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA. J Clin Microbiol 46:2206–2211. http://dx.doi.org/10.1128/JCM.00055-08
-
(2008)
J Clin Microbiol
, vol.46
, pp. 2206-2211
-
-
Pasternak, A.O.1
Adema, K.W.2
Bakker, M.3
Jurriaans, S.4
Berkhout, B.5
Cornelissen, M.6
Lukashov, V.V.7
-
50
-
-
0032490570
-
Induction of HIV-1 replication in latently infected CD4+ T cells using a combination of cytokines
-
Chun TW, Engel D, Mizell SB, Ehler LA, Fauci AS. 1998. Induction of HIV-1 replication in latently infected CD4+ T cells using a combination of cytokines. J Exp Med 188:83–91. http://dx.doi.org/10.1084/jem.188.1.83
-
(1998)
J Exp Med
, vol.188
, pp. 83-91
-
-
Chun, T.W.1
Engel, D.2
Mizell, S.B.3
Ehler, L.A.4
Fauci, A.S.5
-
51
-
-
0036893434
-
Interleukin-7 induces expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotype
-
Scripture-Adams DD, Brooks DG, Korin YD, Zack JA. 2002. Interleukin-7 induces expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotype. J Virol 76: 13077–13082. http://dx.doi.org/10.1128/JVI.76.24.13077-13082.2002
-
(2002)
J Virol
, vol.76
, pp. 13077-13082
-
-
Scripture-Adams, D.D.1
Brooks, D.G.2
Korin, Y.D.3
Zack, J.A.4
-
52
-
-
13744259064
-
IL-7 is a potent and proviral strainspecific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART
-
Wang FX, Xu Y, Sullivan J, Souder E, Argyris EG, Acheampong EA, Fisher J, Sierra M, Thomson MM, Najera R, Frank I, Kulkosky J, Pomerantz RJ, Nunnari G. 2005. IL-7 is a potent and proviral strainspecific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART. J Clin Invest 115:128–137. http://dx.doi.org/10.1172/JCI22574
-
(2005)
J Clin Invest
, vol.115
, pp. 128-137
-
-
Wang, F.X.1
Xu, Y.2
Sullivan, J.3
Souder, E.4
Argyris, E.G.5
Acheampong, E.A.6
Fisher, J.7
Sierra, M.8
Thomson, M.M.9
Najera, R.10
Frank, I.11
Kulkosky, J.12
Pomerantz, R.J.13
Nunnari, G.14
-
53
-
-
84858714200
-
Dynamic roles for NF-kB in HTLV-I and HIV-1 retroviral pathogenesis
-
Chan JK, Greene WC. 2012. Dynamic roles for NF-kB in HTLV-I and HIV-1 retroviral pathogenesis. Immunol Rev 246:286–310. http://dx.doi.org/10.1111/j.1600-065X.2012.01094.x
-
(2012)
Immunol Rev
, vol.246
, pp. 286-310
-
-
Chan, J.K.1
Greene, W.C.2
-
54
-
-
3242792513
-
Reciprocal regulation of the nuclear factor of activated T cells and HIV-1
-
Pessler F, Cron RQ. 2004. Reciprocal regulation of the nuclear factor of activated T cells and HIV-1. Genes Immun 5:158–167. http://dx.doi.org/10.1038/sj.gene.6364047
-
(2004)
Genes Immun
, vol.5
, pp. 158-167
-
-
Pessler, F.1
Cron, R.Q.2
-
55
-
-
84892845657
-
An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients
-
Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, Verdin E, Woelk C, Wooden S, Xing S, Planelles V. 2013. An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients. PLoS Pathog 9:e1003834. http://dx.doi.org/10.1371/journal.ppat.1003834
-
(2013)
Plos Pathog
, vol.9
-
-
Spina, C.A.1
Erson, J.2
Archin, N.M.3
Bosque, A.4
Chan, J.5
Famiglietti, M.6
Greene, W.C.7
Kashuba, A.8
Lewin, S.R.9
Margolis, D.M.10
Mau, M.11
Ruelas, D.12
Saleh, S.13
Shirakawa, K.14
Siliciano, R.F.15
Singhania, A.16
Soto, P.C.17
Terry, V.H.18
Verdin, E.19
Woelk, C.20
Wooden, S.21
Xing, S.22
Planelles, V.23
more..
-
56
-
-
84856484784
-
Control of HIV latency by epigenetic and non-epigenetic mechanisms
-
Mbonye U, Karn J. 2011. Control of HIV latency by epigenetic and non-epigenetic mechanisms. Curr HIV Res 9:554–567. http://dx.doi.org/10.2174/157016211798998736
-
(2011)
Curr HIV Res
, vol.9
, pp. 554-567
-
-
Mbonye, U.1
Karn, J.2
-
57
-
-
22744441386
-
Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity
-
Weinberger LS, Burnett JC, Toettcher JE, Arkin AP, Schaffer DV. 2005. Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity. Cell 122:169–182. http://dx.doi.org/10.1016/j.cell.2005.06.006
-
(2005)
Cell
, vol.122
, pp. 169-182
-
-
Weinberger, L.S.1
Burnett, J.C.2
Toettcher, J.E.3
Arkin, A.P.4
Schaffer, D.V.5
-
58
-
-
77953916829
-
Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection
-
Hocqueloux L, Prazuck T, Avettand-Fenoel V, Lafeuillade A, Cardon B, Viard JP, Rouzioux C. 2010. Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection. AIDS 24:1598–1601. http://dx.doi.org/10.1097/QAD.0b013e32833b61ba
-
(2010)
AIDS
, vol.24
, pp. 1598-1601
-
-
Hocqueloux, L.1
Prazuck, T.2
Avettand-Fenoel, V.3
Lafeuillade, A.4
Cardon, B.5
Viard, J.P.6
Rouzioux, C.7
-
59
-
-
0025948467
-
Oscillation of the human immunodeficiency virus surface receptor is regulated by the state of viral activation in a CD4+ cell model of chronic infection
-
Butera ST, Perez VL, Wu BY, Nabel GJ, Folks TM. 1991. Oscillation of the human immunodeficiency virus surface receptor is regulated by the state of viral activation in a CD4+ cell model of chronic infection. J Virol 65:4645–4653
-
(1991)
J Virol
, vol.65
, pp. 4645-4653
-
-
Butera, S.T.1
Perez, V.L.2
Wu, B.Y.3
Nabel, G.J.4
Folks, T.M.5
-
60
-
-
0037446948
-
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro
-
Jordan A, Bisgrove D, Verdin E. 2003. HIV reproducibly establishes a latent infection after acute infection of T cells in vitro. EMBO J 22: 1868–1877. http://dx.doi.org/10.1093/emboj/cdg188
-
(2003)
EMBO J
, vol.22
, pp. 1868-1877
-
-
Jordan, A.1
Bisgrove, D.2
Verdin, E.3
-
61
-
-
78651476886
-
In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus
-
Chávez L, Kauder S, Verdin E. 2011. In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus. Methods 53:47–53. http://dx.doi.org/10.1016/j.ymeth.2010.05.009
-
(2011)
Methods
, vol.53
, pp. 47-53
-
-
Chávez, L.1
Kauder, S.2
Verdin, E.3
-
62
-
-
67650925025
-
Epigenetic regulation of HIV-1 latency by cytosine methylation
-
Kauder SE, Bosque A, Lindqvist A, Planelles V, Verdin E. 2009. Epigenetic regulation of HIV-1 latency by cytosine methylation. PLoS Pathog 5:e1000495. http://dx.doi.org/10.1371/journal.ppat.1000495
-
(2009)
Plos Pathog
, vol.5
-
-
Kauder, S.E.1
Bosque, A.2
Lindqvist, A.3
Planelles, V.4
Verdin, E.5
-
63
-
-
0024328679
-
Mechanisms of T cell activation by the calcium ionophore ionomycin
-
Chatila T, Silverman L, Miller R, Geha R. 1989. Mechanisms of T cell activation by the calcium ionophore ionomycin. J Immunol 143: 1283–1289
-
(1989)
J Immunol
, vol.143
, pp. 1283-1289
-
-
Chatila, T.1
Silverman, L.2
Miller, R.3
Geha, R.4
-
64
-
-
0023630114
-
Activation of the HIV-1 LTR by T cell mitogens and the transactivator protein of HTLV-I
-
Siekevitz M, Josephs SF, Dukovich M, Peffer N, Wong-Staal F, Greene WC. 1987. Activation of the HIV-1 LTR by T cell mitogens and the transactivator protein of HTLV-I. Science 238:1575–1578. http://dx.doi.org/10.1126/science.2825351
-
(1987)
Science
, vol.238
, pp. 1575-1578
-
-
Siekevitz, M.1
Josephs, S.F.2
Dukovich, M.3
Peffer, N.4
Wong-Staal, F.5
Greene, W.C.6
-
65
-
-
12044259166
-
Characterization of a functional NF-kappa B site in the human interleukin 1bpromoter: Evidence for a positive autoregulatory loop
-
Hiscott J, Marois J, Garoufalis J, D’Addario M, Roulston A, Kwan I, Pepin N, Lacoste J, Nguyen H, Bensi G, et al. 1993. Characterization of a functional NF-kappa B site in the human interleukin 1bpromoter: evidence for a positive autoregulatory loop. Mol Cell Biol 13:6231–6240
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6231-6240
-
-
Hiscott, J.1
Marois, J.2
Garoufalis, J.3
D’Addario, M.4
Roulston, A.5
Kwan, I.6
Pepin, N.7
Lacoste, J.8
Nguyen, H.9
Bensi, G.10
-
66
-
-
0027326410
-
Protein kinase C alpha activates RAF-1 by direct phosphorylation
-
Kolch W, Heidecker G, Kochs G, Hummel R, Vahidi H, Mischak H, Finkenzeller G, Marmé D, Rapp UR. 1993. Protein kinase C alpha activates RAF-1 by direct phosphorylation. Nature 364:249–252. http://dx.doi.org/10.1038/364249a0
-
(1993)
Nature
, vol.364
, pp. 249-252
-
-
Kolch, W.1
Heidecker, G.2
Kochs, G.3
Hummel, R.4
Vahidi, H.5
Mischak, H.6
Finkenzeller, G.7
Marmé, D.8
Rapp, U.R.9
-
67
-
-
36048949732
-
Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication
-
Schneidewind A, Brockman MA, Yang R, Adam RI, Li B, Le Gall S, Rinaldo CR, Craggs SL, Allgaier RL, Power KA, Kuntzen T, Tung CS, LaBute MX, Mueller SM, Harrer T, McMichael AJ, Goulder PJ, Aiken C, Brander C, Kelleher AD, Allen TM. 2007. Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication. J Virol 81:12382–12393. http://dx.doi.org/10.1128/JVI.01543-07
-
(2007)
J Virol
, vol.81
, pp. 12382-12393
-
-
Schneidewind, A.1
Brockman, M.A.2
Yang, R.3
Adam, R.I.4
Li, B.5
Le Gall, S.6
Rinaldo, C.R.7
Craggs, S.L.8
Allgaier, R.L.9
Power, K.A.10
Kuntzen, T.11
Tung, C.S.12
Labute, M.X.13
Mueller, S.M.14
Harrer, T.15
McMichael, A.J.16
Goulder, P.J.17
Aiken, C.18
Brander, C.19
Kelleher, A.D.20
Allen, T.M.21
more..
-
68
-
-
84864939469
-
Protein kinase C: One pathway towards the eradication of latent HIV-1 reservoirs
-
McKernan LN, Momjian D, Kulkosky J. 2012. Protein kinase C: one pathway towards the eradication of latent HIV-1 reservoirs. Adv Virol 2012:805347. http://dx.doi.org/10.1155/2012/805347
-
(2012)
Adv Virol
, vol.2012
-
-
McKernan, L.N.1
Momjian, D.2
Kulkosky, J.3
-
69
-
-
4744359117
-
Prostratin antagonizes HIV latency by activating NF-kB
-
Williams SA, Chen LF, Kwon H, Fenard D, Bisgrove D, Verdin E, Greene WC. 2004. Prostratin antagonizes HIV latency by activating NF-kB. J Biol Chem 279:42008–42017. http://dx.doi.org/10.1074/jbc.M402124200
-
(2004)
J Biol Chem
, vol.279
, pp. 42008-42017
-
-
Williams, S.A.1
Chen, L.F.2
Kwon, H.3
Fenard, D.4
Bisgrove, D.5
Verdin, E.6
Greene, W.C.7
-
70
-
-
60849127627
-
Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid
-
Archin NM, Espeseth A, Parker D, Cheema M, Hazuda D, Margolis DM. 2009. Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid. AIDS Res Hum Retroviruses 25: 207–212. http://dx.doi.org/10.1089/aid.2008.0191
-
(2009)
AIDS Res Hum Retroviruses
, vol.25
, pp. 207-212
-
-
Archin, N.M.1
Espeseth, A.2
Parker, D.3
Cheema, M.4
Hazuda, D.5
Margolis, D.M.6
-
71
-
-
0024509396
-
Monokine regulation of human immunodeficiency virus-1 expression in a chronically infected human T cell clone
-
Clouse KA, Powell D, Washington I, Poli G, Strebel K, Farrar W, Barstad P, Kovacs J, Fauci AS, Folks TM. 1989. Monokine regulation of human immunodeficiency virus-1 expression in a chronically infected human T cell clone. J Immunol 142:431–438
-
(1989)
J Immunol
, vol.142
, pp. 431-438
-
-
Clouse, K.A.1
Powell, D.2
Washington, I.3
Poli, G.4
Strebel, K.5
Farrar, W.6
Barstad, P.7
Kovacs, J.8
Fauci, A.S.9
Folks, T.M.10
-
72
-
-
0010472999
-
Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone
-
Folks TM, Clouse KA, Justement J, Rabson A, Duh E, Kehrl JH, Fauci AS. 1989. Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone. Proc Natl Acad Sci U S A 86:2365–2368. http://dx.doi.org/10.1073/pnas.86.7.2365
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 2365-2368
-
-
Folks, T.M.1
Clouse, K.A.2
Justement, J.3
Rabson, A.4
Duh, E.5
Kehrl, J.H.6
Fauci, A.S.7
-
73
-
-
0023508507
-
Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line
-
Folks TM, Justement J, Kinter A, Dinarello CA, Fauci AS. 1987. Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line. Science 238:800–802. http://dx.doi.org/10.1126/science.3313729
-
(1987)
Science
, vol.238
, pp. 800-802
-
-
Folks, T.M.1
Justement, J.2
Kinter, A.3
Dinarello, C.A.4
Fauci, A.S.5
-
74
-
-
0028140145
-
Analysis of Tat function in human immunodeficiency virus type 1-infected low-level-expression cell lines U1 and ACH-2
-
Cannon P, Kim SH, Ulich C, Kim S. 1994. Analysis of Tat function in human immunodeficiency virus type 1-infected low-level-expression cell lines U1 and ACH-2. J Virol 68:1993–1997
-
(1994)
J Virol
, vol.68
, pp. 1993-1997
-
-
Cannon, P.1
Kim, S.H.2
Ulich, C.3
Kim, S.4
-
75
-
-
0029901662
-
A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency
-
Emiliani S, Van Lint C, Fischle W, Paras P, Jr., Ott M, Brady J, Verdin E. 1996. A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency. Proc Natl Acad SciUSA93:6377–6381. http://dx.doi.org/10.1073/pnas.93.13.6377
-
(1996)
Proc Natl Acad Sciusa93
, pp. 6377-6381
-
-
Emiliani, S.1
Van Lint, C.2
Fischle, W.3
Paras, P.4
Ott, M.5
Brady, J.6
Verdin, E.7
-
76
-
-
0031931047
-
Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line
-
Emiliani S, Fischle W, Ott M, Van Lint C, Amella CA, Verdin E. 1998. Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line. J Virol 72: 1666–1670
-
(1998)
J Virol
, vol.72
, pp. 1666-1670
-
-
Emiliani, S.1
Fischle, W.2
Ott, M.3
Van Lint, C.4
Amella, C.A.5
Verdin, E.6
-
77
-
-
0037709900
-
Differential activation of Tat variants in mitogen-stimulated cells: Implications for HIV-1 postintegration latency
-
Reza SM, Rosetti M, Mathews MB, Pe’ery T. 2003. Differential activation of Tat variants in mitogen-stimulated cells: implications for HIV-1 postintegration latency. Virology 310:141–156. http://dx.doi.org/10.1016/S0042-6822(03)00106-5
-
(2003)
Virology
, vol.310
, pp. 141-156
-
-
Reza, S.M.1
Rosetti, M.2
Mathews, M.B.3
Pe’Ery, T.4
-
78
-
-
0028301838
-
Cellular latency in human immunode- ficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts
-
Adams M, Sharmeen L, Kimpton J, Romeo JM, Garcia JV, Peterlin BM, Groudine M, Emerman M. 1994. Cellular latency in human immunode- ficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts. Proc Natl Acad Sci U S A 91:3862–3866. http://dx.doi.org/10.1073/pnas.91.9.3862
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 3862-3866
-
-
Adams, M.1
Sharmeen, L.2
Kimpton, J.3
Romeo, J.M.4
Garcia, J.V.5
Peterlin, B.M.6
Groudine, M.7
Emerman, M.8
-
79
-
-
0033541971
-
Limitation of Tatassociated transcriptional processivity in HIV-infected PBMC
-
Adams M, Wong C, Wang D, Romeo J. 1999. Limitation of Tatassociated transcriptional processivity in HIV-infected PBMC. Virology 257:397–405. http://dx.doi.org/10.1006/viro.1999.9647
-
(1999)
Virology
, vol.257
, pp. 397-405
-
-
Adams, M.1
Wong, C.2
Wang, D.3
Romeo, J.4
-
80
-
-
0030914237
-
HIV-1 Tat induces the expression of the interleukin-6 (IL6) gene by binding to the IL6 leader RNA and by interacting with CAAT enhancer-binding protein beta (NF-IL6) transcription factors
-
Ambrosino C, Ruocco MR, Chen X, Mallardo M, Baudi F, Trematerra S, Quinto I, Venuta S, Scala G. 1997. HIV-1 Tat induces the expression of the interleukin-6 (IL6) gene by binding to the IL6 leader RNA and by interacting with CAAT enhancer-binding protein beta (NF-IL6) transcription factors. J Biol Chem 272:14883–14892. http://dx.doi.org/10.1074/jbc.272.23.14883
-
(1997)
J Biol Chem
, vol.272
, pp. 14883-14892
-
-
Ambrosino, C.1
Ruocco, M.R.2
Chen, X.3
Mallardo, M.4
Baudi, F.5
Trematerra, S.6
Quinto, I.7
Venuta, S.8
Scala, G.9
-
81
-
-
44149117974
-
PP2B and PP1acooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling
-
Chen R, Liu M, Li H, Xue Y, Ramey WN, He N, Ai N, Luo H, Zhu Y, Zhou N, Zhou Q. 2008. PP2B and PP1acooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling. Genes Dev 22:1356–1368. http://dx.doi.org/10.1101/gad.1636008
-
(2008)
Genes Dev
, vol.22
, pp. 1356-1368
-
-
Chen, R.1
Liu, M.2
Li, H.3
Xue, Y.4
Ramey, W.N.5
He, N.6
Ai, N.7
Luo, H.8
Zhu, Y.9
Zhou, N.10
Zhou, Q.11
-
82
-
-
0031925242
-
Modulation of Sp1 phosphorylation by human immunodeficiency virus type 1 Tat
-
Chun RF, Semmes OJ, Neuveut C, Jeang KT. 1998. Modulation of Sp1 phosphorylation by human immunodeficiency virus type 1 Tat. J Virol 72:2615–2629
-
(1998)
J Virol
, vol.72
, pp. 2615-2629
-
-
Chun, R.F.1
Semmes, O.J.2
Neuveut, C.3
Jeang, K.T.4
-
83
-
-
0030703134
-
Determination of the minimal amount of Tat activity required for human immunodeficiency virus type 1 replication
-
Verhoef K, Koper M, Berkhout B. 1997. Determination of the minimal amount of Tat activity required for human immunodeficiency virus type 1 replication. Virology 237:228–236. http://dx.doi.org/10.1006/viro.1997.8786
-
(1997)
Virology
, vol.237
, pp. 228-236
-
-
Verhoef, K.1
Koper, M.2
Berkhout, B.3
-
84
-
-
0024469503
-
Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations
-
Meyerhans A, Cheynier R, Albert J, Seth M, Kwok S, Sninsky J, Morfeldt-Månson L, Asjö B, Wain-Hobson S. 1989. Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations. Cell 58:901–910 http://dx.doi.org/10.1016/0092-8674(89)90942-2
-
(1989)
Cell
, vol.58
, pp. 901-910
-
-
Meyerhans, A.1
Cheynier, R.2
Albert, J.3
Seth, M.4
Kwok, S.5
Sninsky, J.6
Morfeldt-Månson, L.7
Asjö, B.8
Wain-Hobson, S.9
-
85
-
-
0027816932
-
An individual with a high prevalence of a tat-defective provirus in peripheral blood
-
Sabino E, Cheng-Mayer C, Mayer A. 1993. An individual with a high prevalence of a tat-defective provirus in peripheral blood. AIDS Res Hum Retroviruses 9:1265–1268. http://dx.doi.org/10.1089/aid.1993.9.1265
-
(1993)
AIDS Res Hum Retroviruses
, vol.9
, pp. 1265-1268
-
-
Sabino, E.1
Cheng-Mayer, C.2
Mayer, A.3
-
86
-
-
84857948627
-
The viral protein Tat can inhibit the establishment of HIV-1 latency
-
Donahue DA, Kuhl BD, Sloan RD, Wainberg MA. 2012. The viral protein Tat can inhibit the establishment of HIV-1 latency. J Virol 86: 3253–3263. http://dx.doi.org/10.1128/JVI.06648-11
-
(2012)
J Virol
, vol.86
, pp. 3253-3263
-
-
Donahue, D.A.1
Kuhl, B.D.2
Sloan, R.D.3
Wainberg, M.A.4
-
87
-
-
84864203255
-
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
-
Archin NM, Liberty AL, Kashuba AD, Choudhary SK, Kuruc JD, Crooks AM, Parker DC, Anderson EM, Kearney MF, Strain MC, Richman DD, Hudgens MG, Bosch RJ, Coffin JM, Eron JJ, Hazuda DJ, Margolis DM. 2012. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature 487:482–485. http://dx.doi.org/10.1038/nature11286
-
(2012)
Nature
, vol.487
, pp. 482-485
-
-
Archin, N.M.1
Liberty, A.L.2
Kashuba, A.D.3
Choudhary, S.K.4
Kuruc, J.D.5
Crooks, A.M.6
Parker, D.C.7
Erson, E.M.8
Kearney, M.F.9
Strain, M.C.10
Richman, D.D.11
Hudgens, M.G.12
Bosch, R.J.13
Coffin, J.M.14
Eron, J.J.15
Hazuda, D.J.16
Margolis, D.M.17
-
88
-
-
84864243685
-
HIV: Shock and kill
-
Deeks SG. 2012. HIV: shock and kill. Nature 487:439–440. http://dx.doi.org/10.1038/487439a
-
(2012)
Nature
, vol.487
, pp. 439-440
-
-
Deeks, S.G.1
-
89
-
-
84863337769
-
Stimulation of HIV-1- specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation
-
Shan L, Deng K, Shroff NS, Durand CM, Rabi SA, Yang HC, Zhang H, Margolick JB, Blankson JN, Siliciano RF. 2012. Stimulation of HIV-1- specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation. Immunity 36:491–501. http://dx.doi.org/10.1016/j.immuni.2012.01.014
-
(2012)
Immunity
, vol.36
, pp. 491-501
-
-
Shan, L.1
Deng, K.2
Shroff, N.S.3
Durand, C.M.4
Rabi, S.A.5
Yang, H.C.6
Zhang, H.7
Margolick, J.B.8
Blankson, J.N.9
Siliciano, R.F.10
-
90
-
-
84912122037
-
Activation of HIV transcription with short-course vorinostat in HIVinfected patients on suppressive antiretroviral therapy
-
Elliott JH, Wightman F, Solomon A, Ghneim K, Ahlers J, Cameron MJ, Smith MZ, Spelman T, McMahon J, Velayudham P, Brown G, Roney J, Watson J, Prince MH, Hoy JF, Chomont N, Fromentin R, Procopio FA, Zeidan J, Palmer S, Odevall L, Johnstone RW, Martin BP, Sinclair E, Deeks SG, Hazuda DJ, Cameron PU, Sekaly RP, Lewin SR. 2014. Activation of HIV transcription with short-course vorinostat in HIVinfected patients on suppressive antiretroviral therapy. PLoS Pathog 10: e1004473. http://dx.doi.org/10.1371/journal.ppat.1004473
-
(2014)
Plos Pathog
, vol.10
-
-
Elliott, J.H.1
Wightman, F.2
Solomon, A.3
Ghneim, K.4
Ahlers, J.5
Cameron, M.J.6
Smith, M.Z.7
Spelman, T.8
McMahon, J.9
Velayudham, P.10
Brown, G.11
Roney, J.12
Watson, J.13
Prince, M.H.14
Hoy, J.F.15
Chomont, N.16
Fromentin, R.17
Procopio, F.A.18
Zeidan, J.19
Palmer, S.20
Odevall, L.21
Johnstone, R.W.22
Martin, B.P.23
Sinclair, E.24
Deeks, S.G.25
Hazuda, D.J.26
Cameron, P.U.27
Sekaly, R.P.28
Lewin, S.R.29
more..
-
91
-
-
0033984045
-
The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged antiretroviral therapy
-
Ramratnam B, Mittler JE, Zhang L, Boden D, Hurley A, Fang F, Macken CA, Perelson AS, Markowitz M, Ho DD. 2000. The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged antiretroviral therapy. Nat Med 6:82–85. http://dx.doi.org/10.1038/71577.
-
(2000)
Nat Med
, vol.6
, pp. 82-85
-
-
Ramratnam, B.1
Mittler, J.E.2
Zhang, L.3
Boden, D.4
Hurley, A.5
Fang, F.6
Macken, C.A.7
Perelson, A.S.8
Markowitz, M.9
Ho, D.D.10
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