Regulation of senescence associated signaling mechanisms in chondrocytes for cartilage tissue regeneration

Osteoarthritis and Cartilage

Volumn 24, Issue 2, 2016, Pages 196-205

  Ashraf, S ^a,b   Cha, B H ^b   Kim, J S ^b   Ahn, J ^b   Han, I ^c   Park, H ^a   Lee, S H ^b  

^a Chung Ang University   (South Korea)

^b CHA University   (South Korea)

^c CHA University   (South Korea)

Author keywords

Cartilage; Chondrocytes; Dedifferentiation; Genes; Senescence

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 1; COLLAGEN TYPE 2; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P16; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN C; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA; CYCLIN DEPENDENT KINASE INHIBITOR 1A;

CARTILAGE CELL; CARTILAGE DEGENERATION; CELL FATE; CELL LINEAGE; CHONDROGENESIS; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; HUMAN; IGF 1 GENE; IL 1BETA GENE; IN VITRO STUDY; INTRACELLULAR SIGNALING; NONHUMAN; OXIDATIVE STRESS; P16 GENE; P21 GENE; P38 GENE; P53 GENE; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; SENESCENCE; TGF BETA GENE; ANIMAL; ARTICULAR CARTILAGE; CELL AGING; CELL DEDIFFERENTIATION; CHONDROCYTE; GENETICS; METABOLISM; SIGNAL TRANSDUCTION; TISSUE REGENERATION; TUMOR SUPPRESSOR GENE; UPREGULATION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CARTILAGE, ARTICULAR; CELL AGING; CELL DEDIFFERENTIATION; CHONDROCYTES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GENE EXPRESSION REGULATION; GENES, P16; GENES, P53; GUIDED TISSUE REGENERATION; HUMANS; IN VITRO TECHNIQUES; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-1BETA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; SOX9 TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84955683397     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2015.07.008     Document Type: Review

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