-
1
-
-
79960668226
-
Polyglutamine diseases: the special case of ataxin-3 and Machado-Joseph disease
-
Matos C.A., de Macedo-Ribeiro S., Carvalho A.L. Polyglutamine diseases: the special case of ataxin-3 and Machado-Joseph disease. Prog. Neurobiol. 2011, 95:26-48.
-
(2011)
Prog. Neurobiol.
, vol.95
, pp. 26-48
-
-
Matos, C.A.1
de Macedo-Ribeiro, S.2
Carvalho, A.L.3
-
2
-
-
67149129949
-
Nucleocytoplasmic shuttling activity of ataxin-3
-
Macedo-Ribeiro S., Cortes L., Maciel P., Carvalho A.L. Nucleocytoplasmic shuttling activity of ataxin-3. PLoS One 2009, 4:e5834.
-
(2009)
PLoS One
, vol.4
, pp. e5834
-
-
Macedo-Ribeiro, S.1
Cortes, L.2
Maciel, P.3
Carvalho, A.L.4
-
3
-
-
70349780383
-
Identification and functional dissection of localization signals within ataxin-3
-
Antony P.M., Mantele S., Mollenkopf P., Boy J., Kehlenbach R.H., Riess O., Schmidt T. Identification and functional dissection of localization signals within ataxin-3. Neurobiol. Dis. 2009, 36:280-292.
-
(2009)
Neurobiol. Dis.
, vol.36
, pp. 280-292
-
-
Antony, P.M.1
Mantele, S.2
Mollenkopf, P.3
Boy, J.4
Kehlenbach, R.H.5
Riess, O.6
Schmidt, T.7
-
4
-
-
0032735135
-
Ataxin-3 with an altered conformation that exposes the polyglutamine domain is associated with the nuclear matrix
-
Perez M.K., Paulson H.L., Pittman R.N. Ataxin-3 with an altered conformation that exposes the polyglutamine domain is associated with the nuclear matrix. Hum. Mol. Genet. 1999, 8:2377-2385.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 2377-2385
-
-
Perez, M.K.1
Paulson, H.L.2
Pittman, R.N.3
-
5
-
-
0345099501
-
The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity
-
Burnett B., Li F., Pittman R.N. The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity. Hum. Mol. Genet. 2003, 12:3195-3205.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 3195-3205
-
-
Burnett, B.1
Li, F.2
Pittman, R.N.3
-
6
-
-
0042691818
-
Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis
-
Doss-Pepe E.W., Stenroos E.S., Johnson W.G., Madura K. Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis. Mol. Cell. Biol. 2003, 23:6469-6483.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6469-6483
-
-
Doss-Pepe, E.W.1
Stenroos, E.S.2
Johnson, W.G.3
Madura, K.4
-
7
-
-
33747891213
-
Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates
-
Zhong X., Pittman R.N. Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates. Hum. Mol. Genet. 2006, 15:2409-2420.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 2409-2420
-
-
Zhong, X.1
Pittman, R.N.2
-
8
-
-
33750962224
-
Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation
-
Evert B.O., Araujo J., Vieira-Saecker A.M., de Vos R.A., Harendza S., Klockgether T., Wullner U. Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation. J. Neurosci. 2006, 26:11474-11486.
-
(2006)
J. Neurosci.
, vol.26
, pp. 11474-11486
-
-
Evert, B.O.1
Araujo, J.2
Vieira-Saecker, A.M.3
de Vos, R.A.4
Harendza, S.5
Klockgether, T.6
Wullner, U.7
-
9
-
-
77955655871
-
Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death
-
Rodrigues A.J., do Carmo Costa M., Silva T.L., Ferreira D., Bajanca F., Logarinho E., Maciel P. Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death. Biochim. Biophys. Acta 2010, 1803:1154-1163.
-
(2010)
Biochim. Biophys. Acta
, vol.1803
, pp. 1154-1163
-
-
Rodrigues, A.J.1
do Carmo Costa, M.2
Silva, T.L.3
Ferreira, D.4
Bajanca, F.5
Logarinho, E.6
Maciel, P.7
-
10
-
-
77955369713
-
Ataxin-3 plays a role in mouse myogenic differentiation through regulation of integrin subunit levels
-
do Carmo Costa M., Bajanca F., Rodrigues A.J., Tome R.J., Corthals G., Macedo-Ribeiro S., Paulson H.L., Logarinho E., Maciel P. Ataxin-3 plays a role in mouse myogenic differentiation through regulation of integrin subunit levels. PLoS One 2010, 5:e11728.
-
(2010)
PLoS One
, vol.5
, pp. e11728
-
-
do Carmo Costa, M.1
Bajanca, F.2
Rodrigues, A.J.3
Tome, R.J.4
Corthals, G.5
Macedo-Ribeiro, S.6
Paulson, H.L.7
Logarinho, E.8
Maciel, P.9
-
11
-
-
0035833997
-
An expanded glutamine repeat destabilizes native ataxin-3 structure and mediates formation of parallel beta-fibrils
-
Bevivino A.E., Loll P.J. An expanded glutamine repeat destabilizes native ataxin-3 structure and mediates formation of parallel beta-fibrils. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:11955-11960.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 11955-11960
-
-
Bevivino, A.E.1
Loll, P.J.2
-
12
-
-
0042357191
-
Structural instability and fibrillar aggregation of non-expanded human ataxin-3 revealed under high pressure and temperature
-
Marchal S., Shehi E., Harricane M.C., Fusi P., Heitz F., Tortora P., Lange R. Structural instability and fibrillar aggregation of non-expanded human ataxin-3 revealed under high pressure and temperature. J. Biol. Chem. 2003, 278:31554-31563.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31554-31563
-
-
Marchal, S.1
Shehi, E.2
Harricane, M.C.3
Fusi, P.4
Heitz, F.5
Tortora, P.6
Lange, R.7
-
13
-
-
0345118103
-
Destabilization of a non-pathological variant of ataxin-3 results in fibrillogenesis via a partially folded intermediate: a model for misfolding in polyglutamine disease
-
Chow M.K., Paulson H.L., Bottomley S.P. Destabilization of a non-pathological variant of ataxin-3 results in fibrillogenesis via a partially folded intermediate: a model for misfolding in polyglutamine disease. J. Mol. Biol. 2004, 335:333-341.
-
(2004)
J. Mol. Biol.
, vol.335
, pp. 333-341
-
-
Chow, M.K.1
Paulson, H.L.2
Bottomley, S.P.3
-
14
-
-
8544260320
-
Characterization of the structure and the amyloidogenic properties of the Josephin domain of the polyglutamine-containing protein ataxin-3
-
Masino L., Nicastro G., Menon R.P., Dal Piaz F., Calder L., Pastore A. Characterization of the structure and the amyloidogenic properties of the Josephin domain of the polyglutamine-containing protein ataxin-3. J. Mol. Biol. 2004, 344:1021-1035.
-
(2004)
J. Mol. Biol.
, vol.344
, pp. 1021-1035
-
-
Masino, L.1
Nicastro, G.2
Menon, R.P.3
Dal Piaz, F.4
Calder, L.5
Pastore, A.6
-
15
-
-
26244434741
-
Towards a structural understanding of the fibrillization pathway in Machado-Joseph's disease: trapping early oligomers of non-expanded ataxin-3
-
Gales L., Cortes L., Almeida C., Melo C.V., Costa M.C., Maciel P., Clarke D.T., Damas A.M., Macedo-Ribeiro S. Towards a structural understanding of the fibrillization pathway in Machado-Joseph's disease: trapping early oligomers of non-expanded ataxin-3. J. Mol. Biol. 2005, 353:642-654.
-
(2005)
J. Mol. Biol.
, vol.353
, pp. 642-654
-
-
Gales, L.1
Cortes, L.2
Almeida, C.3
Melo, C.V.4
Costa, M.C.5
Maciel, P.6
Clarke, D.T.7
Damas, A.M.8
Macedo-Ribeiro, S.9
-
16
-
-
77955647254
-
Towards the treatment of polyglutamine diseases: the modulatory role of protein context
-
Robertson A.L., Bottomley S.P. Towards the treatment of polyglutamine diseases: the modulatory role of protein context. Curr. Med. Chem. 2010, 17:3058-3068.
-
(2010)
Curr. Med. Chem.
, vol.17
, pp. 3058-3068
-
-
Robertson, A.L.1
Bottomley, S.P.2
-
17
-
-
84883533687
-
Trinucleotide repeats: a structural perspective
-
Almeida B., Fernandes S., Abreu I.A., Macedo-Ribeiro S. Trinucleotide repeats: a structural perspective. Front. Neurol. 2013, 4:76.
-
(2013)
Front. Neurol.
, vol.4
, pp. 76
-
-
Almeida, B.1
Fernandes, S.2
Abreu, I.A.3
Macedo-Ribeiro, S.4
-
18
-
-
84857033477
-
The two faces of Janus: functional interactions and protein aggregation
-
Pastore A., Temussi P.A. The two faces of Janus: functional interactions and protein aggregation. Curr. Opin. Struct. Biol. 2012, 22:30-37.
-
(2012)
Curr. Opin. Struct. Biol.
, vol.22
, pp. 30-37
-
-
Pastore, A.1
Temussi, P.A.2
-
19
-
-
84861943506
-
Cell biology of spinocerebellar ataxia
-
Orr H.T. Cell biology of spinocerebellar ataxia. J. Cell Biol. 2012, 197:167-177.
-
(2012)
J. Cell Biol.
, vol.197
, pp. 167-177
-
-
Orr, H.T.1
-
21
-
-
84861538096
-
Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks
-
Schaefer M.H., Wanker E.E., Andrade-Navarro M.A. Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks. Nucleic Acids Res. 2012, 40:4273-4287.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 4273-4287
-
-
Schaefer, M.H.1
Wanker, E.E.2
Andrade-Navarro, M.A.3
-
22
-
-
78649811312
-
Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117
-
Todi S.V., Scaglione K.M., Blount J.R., Basrur V., Conlon K.P., Pastore A., Elenitoba-Johnson K., Paulson H.L. Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117. J. Biol. Chem. 2010, 285:39303-39313.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 39303-39313
-
-
Todi, S.V.1
Scaglione, K.M.2
Blount, J.R.3
Basrur, V.4
Conlon, K.P.5
Pastore, A.6
Elenitoba-Johnson, K.7
Paulson, H.L.8
-
23
-
-
63149139630
-
Post-translational modifications of expanded polyglutamine proteins: impact on neurotoxicity
-
Pennuto M., Palazzolo I., Poletti A. Post-translational modifications of expanded polyglutamine proteins: impact on neurotoxicity. Hum. Mol. Genet. 2009, 18:R40-R47.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. R40-R47
-
-
Pennuto, M.1
Palazzolo, I.2
Poletti, A.3
-
24
-
-
60549100850
-
Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3
-
Todi S.V., Winborn B.J., Scaglione K.M., Blount J.R., Travis S.M., Paulson H.L. Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3. EMBO J. 2009, 28:372-382.
-
(2009)
EMBO J.
, vol.28
, pp. 372-382
-
-
Todi, S.V.1
Winborn, B.J.2
Scaglione, K.M.3
Blount, J.R.4
Travis, S.M.5
Paulson, H.L.6
-
25
-
-
11144353613
-
SUMO modification of Huntingtin and Huntington's disease pathology
-
Steffan J.S., Agrawal N., Pallos J., Rockabrand E., Trotman L.C., Slepko N., Illes K., Lukacsovich T., Zhu Y.Z., Cattaneo E., Pandolfi P.P., Thompson L.M., Marsh J.L. SUMO modification of Huntingtin and Huntington's disease pathology. Science 2004, 304:100-104.
-
(2004)
Science
, vol.304
, pp. 100-104
-
-
Steffan, J.S.1
Agrawal, N.2
Pallos, J.3
Rockabrand, E.4
Trotman, L.C.5
Slepko, N.6
Illes, K.7
Lukacsovich, T.8
Zhu, Y.Z.9
Cattaneo, E.10
Pandolfi, P.P.11
Thompson, L.M.12
Marsh, J.L.13
-
26
-
-
20444467297
-
SUMOylation of the polyglutamine repeat protein, ataxin-1, is dependent on a functional nuclear localization signal
-
Riley B.E., Zoghbi H.Y., Orr H.T. SUMOylation of the polyglutamine repeat protein, ataxin-1, is dependent on a functional nuclear localization signal. J. Biol. Chem. 2005, 280:21942-21948.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 21942-21948
-
-
Riley, B.E.1
Zoghbi, H.Y.2
Orr, H.T.3
-
27
-
-
77649186048
-
SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7
-
Janer A., Werner A., Takahashi-Fujigasaki J., Daret A., Fujigasaki H., Takada K., Duyckaerts C., Brice A., Dejean A., Sittler A. SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7. Hum. Mol. Genet. 2010, 19:181-195.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 181-195
-
-
Janer, A.1
Werner, A.2
Takahashi-Fujigasaki, J.3
Daret, A.4
Fujigasaki, H.5
Takada, K.6
Duyckaerts, C.7
Brice, A.8
Dejean, A.9
Sittler, A.10
-
28
-
-
77649184659
-
Oxidative stress-enhanced SUMOylation and aggregation of ataxin-1: Implication of JNK pathway
-
Ryu J., Cho S., Park B.C., Lee do H. Oxidative stress-enhanced SUMOylation and aggregation of ataxin-1: Implication of JNK pathway. Biochem. Biophys. Res. Commun. 2010, 393:280-285.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.393
, pp. 280-285
-
-
Ryu, J.1
Cho, S.2
Park, B.C.3
Lee do, H.4
-
29
-
-
69249090927
-
Small ubiquitin-like modifier (SUMO) modification of the androgen receptor attenuates polyglutamine-mediated aggregation
-
Mukherjee S., Thomas M., Dadgar N., Lieberman A.P., Iniguez-Lluhi J.A. Small ubiquitin-like modifier (SUMO) modification of the androgen receptor attenuates polyglutamine-mediated aggregation. J. Biol. Chem. 2009, 284:21296-21306.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 21296-21306
-
-
Mukherjee, S.1
Thomas, M.2
Dadgar, N.3
Lieberman, A.P.4
Iniguez-Lluhi, J.A.5
-
30
-
-
84878844824
-
A tale of a tail: structural insights into the conformational properties of the polyglutamine protein ataxin-3
-
Scarff C.A., Sicorello A., Tomé R.J.L., Macedo-Ribeiro S., Ashcroft A.E., Radford S.E. A tale of a tail: structural insights into the conformational properties of the polyglutamine protein ataxin-3. Int. J. Mass Spectrom. 2013, 345-347:63-70.
-
(2013)
Int. J. Mass Spectrom.
, pp. 63-70
-
-
Scarff, C.A.1
Sicorello, A.2
Tomé, R.J.L.3
Macedo-Ribeiro, S.4
Ashcroft, A.E.5
Radford, S.E.6
-
31
-
-
79953009529
-
Crystal structure of a Josephin-ubiquitin complex: evolutionary restraints on ataxin-3 deubiquitinating activity
-
Weeks S.D., Grasty K.C., Hernandez-Cuebas L., Loll P.J. Crystal structure of a Josephin-ubiquitin complex: evolutionary restraints on ataxin-3 deubiquitinating activity. J. Biol. Chem. 2011, 286:4555-4565.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 4555-4565
-
-
Weeks, S.D.1
Grasty, K.C.2
Hernandez-Cuebas, L.3
Loll, P.J.4
-
32
-
-
59249095983
-
Enhanced detection of in vivo SUMO conjugation by Ubc9 fusion-dependent sumoylation (UFDS)
-
Niedenthal R. Enhanced detection of in vivo SUMO conjugation by Ubc9 fusion-dependent sumoylation (UFDS). Methods Mol. Biol. 2009, 497:63-79.
-
(2009)
Methods Mol. Biol.
, vol.497
, pp. 63-79
-
-
Niedenthal, R.1
-
33
-
-
77954957347
-
A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants
-
Tang W.K., Li D., Li C.C., Esser L., Dai R., Guo L., Xia D. A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants. EMBO J. 2010, 29:2217-2229.
-
(2010)
EMBO J.
, vol.29
, pp. 2217-2229
-
-
Tang, W.K.1
Li, D.2
Li, C.C.3
Esser, L.4
Dai, R.5
Guo, L.6
Xia, D.7
-
34
-
-
35548938484
-
NEDD8: a new ataxin-3 interactor
-
Ferro A., Carvalho A.L., Teixeira-Castro A., Almeida C., Tome R.J., Cortes L., Rodrigues A.J., Logarinho E., Sequeiros J., Macedo-Ribeiro S., Maciel P. NEDD8: a new ataxin-3 interactor. Biochim. Biophys. Acta 2007, 1773:1619-1627.
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 1619-1627
-
-
Ferro, A.1
Carvalho, A.L.2
Teixeira-Castro, A.3
Almeida, C.4
Tome, R.J.5
Cortes, L.6
Rodrigues, A.J.7
Logarinho, E.8
Sequeiros, J.9
Macedo-Ribeiro, S.10
Maciel, P.11
-
36
-
-
84902344846
-
A role for stargazin in experience-dependent plasticity
-
Louros S.R., Hooks B.M., Litvina L., Carvalho A.L., Chen C. A role for stargazin in experience-dependent plasticity. Cell Rep. 2014, 7:1614-1625.
-
(2014)
Cell Rep.
, vol.7
, pp. 1614-1625
-
-
Louros, S.R.1
Hooks, B.M.2
Litvina, L.3
Carvalho, A.L.4
Chen, C.5
-
37
-
-
4444354577
-
High Ca(2+)-phosphate transfection efficiency enables single neuron gene analysis
-
Jiang M., Deng L., Chen G. High Ca(2+)-phosphate transfection efficiency enables single neuron gene analysis. Gene Ther. 2004, 11:1303-1311.
-
(2004)
Gene Ther.
, vol.11
, pp. 1303-1311
-
-
Jiang, M.1
Deng, L.2
Chen, G.3
-
38
-
-
0034672325
-
Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set
-
Sreerama N., Woody R.W. Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set. Anal. Biochem. 2000, 287:252-260.
-
(2000)
Anal. Biochem.
, vol.287
, pp. 252-260
-
-
Sreerama, N.1
Woody, R.W.2
-
39
-
-
33745195252
-
The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step
-
Ellisdon A.M., Thomas B., Bottomley S.P. The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step. J. Biol. Chem. 2006, 281:16888-16896.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16888-16896
-
-
Ellisdon, A.M.1
Thomas, B.2
Bottomley, S.P.3
-
40
-
-
78149430698
-
Splice isoforms of the polyglutamine disease protein ataxin-3 exhibit similar enzymatic yet different aggregation properties
-
Harris G.M., Dodelzon K., Gong L., Gonzalez-Alegre P., Paulson H.L. Splice isoforms of the polyglutamine disease protein ataxin-3 exhibit similar enzymatic yet different aggregation properties. PLoS One 2010, 5:e13695.
-
(2010)
PLoS One
, vol.5
, pp. e13695
-
-
Harris, G.M.1
Dodelzon, K.2
Gong, L.3
Gonzalez-Alegre, P.4
Paulson, H.L.5
-
41
-
-
34948867769
-
Ubc9 fusion-directed SUMOylation identifies constitutive and inducible SUMOylation
-
Jakobs A., Himstedt F., Funk M., Korn B., Gaestel M., Niedenthal R. Ubc9 fusion-directed SUMOylation identifies constitutive and inducible SUMOylation. Nucleic Acids Res. 2007, 35:e109.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. e109
-
-
Jakobs, A.1
Himstedt, F.2
Funk, M.3
Korn, B.4
Gaestel, M.5
Niedenthal, R.6
-
42
-
-
33847649960
-
Ubc9 fusion-directed SUMOylation (UFDS): a method to analyze function of protein SUMOylation
-
Jakobs A., Koehnke J., Himstedt F., Funk M., Korn B., Gaestel M., Niedenthal R. Ubc9 fusion-directed SUMOylation (UFDS): a method to analyze function of protein SUMOylation. Nat. Methods 2007, 4:245-250.
-
(2007)
Nat. Methods
, vol.4
, pp. 245-250
-
-
Jakobs, A.1
Koehnke, J.2
Himstedt, F.3
Funk, M.4
Korn, B.5
Gaestel, M.6
Niedenthal, R.7
-
43
-
-
0035929557
-
Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9
-
Tatham M.H., Jaffray E., Vaughan O.A., Desterro J.M., Botting C.H., Naismith J.H., Hay R.T. Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9. J. Biol. Chem. 2001, 276:35368-35374.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35368-35374
-
-
Tatham, M.H.1
Jaffray, E.2
Vaughan, O.A.3
Desterro, J.M.4
Botting, C.H.5
Naismith, J.H.6
Hay, R.T.7
-
44
-
-
33749516084
-
Purification of polyglutamine proteins
-
Chow M.K., Ellisdon A.M., Cabrita L.D., Bottomley S.P. Purification of polyglutamine proteins. Methods Enzymol. 2006, 413:1-19.
-
(2006)
Methods Enzymol.
, vol.413
, pp. 1-19
-
-
Chow, M.K.1
Ellisdon, A.M.2
Cabrita, L.D.3
Bottomley, S.P.4
-
45
-
-
84873176209
-
SUMO-1 modification on K166 of polyQ-expanded ataxin-3 strengthens its stability and increases its cytotoxicity
-
Zhou Y.F., Liao S.S., Luo Y.Y., Tang J.G., Wang J.L., Lei L.F., Chi J.W., Du J., Jiang H., Xia K., Tang B.S., Shen L. SUMO-1 modification on K166 of polyQ-expanded ataxin-3 strengthens its stability and increases its cytotoxicity. PLoS One 2013, 8:e54214.
-
(2013)
PLoS One
, vol.8
, pp. e54214
-
-
Zhou, Y.F.1
Liao, S.S.2
Luo, Y.Y.3
Tang, J.G.4
Wang, J.L.5
Lei, L.F.6
Chi, J.W.7
Du, J.8
Jiang, H.9
Xia, K.10
Tang, B.S.11
Shen, L.12
-
46
-
-
9144264986
-
Polyglutamine expansion in ataxin-3 does not affect protein stability: implications for misfolding and disease
-
Chow M.K., Ellisdon A.M., Cabrita L.D., Bottomley S.P. Polyglutamine expansion in ataxin-3 does not affect protein stability: implications for misfolding and disease. J. Biol. Chem. 2004, 279:47643-47651.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 47643-47651
-
-
Chow, M.K.1
Ellisdon, A.M.2
Cabrita, L.D.3
Bottomley, S.P.4
-
47
-
-
80053156781
-
Flanking domain stability modulates the aggregation kinetics of a polyglutamine disease protein
-
Saunders H.M., Gilis D., Rooman M., Dehouck Y., Robertson A.L., Bottomley S.P. Flanking domain stability modulates the aggregation kinetics of a polyglutamine disease protein. Protein Sci. 2011, 20:1675-1681.
-
(2011)
Protein Sci.
, vol.20
, pp. 1675-1681
-
-
Saunders, H.M.1
Gilis, D.2
Rooman, M.3
Dehouck, Y.4
Robertson, A.L.5
Bottomley, S.P.6
-
48
-
-
33645735557
-
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis
-
Boeddrich A., Gaumer S., Haacke A., Tzvetkov N., Albrecht M., Evert B.O., Muller E.C., Lurz R., Breuer P., Schugardt N., Plassmann S., Xu K., Warrick J.M., Suopanki J., Wullner U., Frank R., Hartl U.F., Bonini N.M., Wanker E.E. An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis. EMBO J. 2006, 25:1547-1558.
-
(2006)
EMBO J.
, vol.25
, pp. 1547-1558
-
-
Boeddrich, A.1
Gaumer, S.2
Haacke, A.3
Tzvetkov, N.4
Albrecht, M.5
Evert, B.O.6
Muller, E.C.7
Lurz, R.8
Breuer, P.9
Schugardt, N.10
Plassmann, S.11
Xu, K.12
Warrick, J.M.13
Suopanki, J.14
Wullner, U.15
Frank, R.16
Hartl, U.F.17
Bonini, N.M.18
Wanker, E.E.19
-
49
-
-
84899751309
-
Structural basis for ovarian tumor domain-containing protein 1 (OTU1) binding to p97/valosin-containing protein (VCP)
-
Kim S.J., Cho J., Song E.J., Kim H.M., Lee K.E., Suh S.W., Kim E.E. Structural basis for ovarian tumor domain-containing protein 1 (OTU1) binding to p97/valosin-containing protein (VCP). J. Biol. Chem. 2014, 289:12264-12274.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 12264-12274
-
-
Kim, S.J.1
Cho, J.2
Song, E.J.3
Kim, H.M.4
Lee, K.E.5
Suh, S.W.6
Kim, E.E.7
-
50
-
-
15744387323
-
Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes
-
Jana N.R., Dikshit P., Goswami A., Kotliarova S., Murata S., Tanaka K., Nukina N. Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes. J. Biol. Chem. 2005, 280:11635-11640.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 11635-11640
-
-
Jana, N.R.1
Dikshit, P.2
Goswami, A.3
Kotliarova, S.4
Murata, S.5
Tanaka, K.6
Nukina, N.7
-
51
-
-
80051745465
-
Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP
-
Scaglione K.M., Zavodszky E., Todi S.V., Patury S., Xu P., Rodriguez-Lebron E., Fischer S., Konen J., Djarmati A., Peng J., Gestwicki J.E., Paulson H.L. Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP. Mol. Cell 2011, 43:599-612.
-
(2011)
Mol. Cell
, vol.43
, pp. 599-612
-
-
Scaglione, K.M.1
Zavodszky, E.2
Todi, S.V.3
Patury, S.4
Xu, P.5
Rodriguez-Lebron, E.6
Fischer, S.7
Konen, J.8
Djarmati, A.9
Peng, J.10
Gestwicki, J.E.11
Paulson, H.L.12
-
52
-
-
84860660444
-
Toward understanding Machado-Joseph disease
-
Costa Mdo C., Paulson H.L. Toward understanding Machado-Joseph disease. Prog. Neurobiol. 2012, 97:239-257.
-
(2012)
Prog. Neurobiol.
, vol.97
, pp. 239-257
-
-
Costa Mdo, C.1
Paulson, H.L.2
-
53
-
-
79251572023
-
Functional interactions as a survival strategy against abnormal aggregation
-
Masino L., Nicastro G., Calder L., Vendruscolo M., Pastore A. Functional interactions as a survival strategy against abnormal aggregation. FASEB J. 2011, 25:45-54.
-
(2011)
FASEB J.
, vol.25
, pp. 45-54
-
-
Masino, L.1
Nicastro, G.2
Calder, L.3
Vendruscolo, M.4
Pastore, A.5
-
54
-
-
33947586837
-
Mechanisms of ataxin-3 misfolding and fibril formation: kinetic analysis of a disease-associated polyglutamine protein
-
Ellisdon A.M., Pearce M.C., Bottomley S.P. Mechanisms of ataxin-3 misfolding and fibril formation: kinetic analysis of a disease-associated polyglutamine protein. J. Mol. Biol. 2007, 368:595-605.
-
(2007)
J. Mol. Biol.
, vol.368
, pp. 595-605
-
-
Ellisdon, A.M.1
Pearce, M.C.2
Bottomley, S.P.3
-
55
-
-
79954618669
-
A major role for side-chain polyglutamine hydrogen bonding in irreversible ataxin-3 aggregation
-
Natalello A., Frana A.M., Relini A., Apicella A., Invernizzi G., Casari C., Gliozzi A., Doglia S.M., Tortora P., Regonesi M.E. A major role for side-chain polyglutamine hydrogen bonding in irreversible ataxin-3 aggregation. PLoS One 2011, 6:e18789.
-
(2011)
PLoS One
, vol.6
, pp. e18789
-
-
Natalello, A.1
Frana, A.M.2
Relini, A.3
Apicella, A.4
Invernizzi, G.5
Casari, C.6
Gliozzi, A.7
Doglia, S.M.8
Tortora, P.9
Regonesi, M.E.10
-
56
-
-
34547683267
-
SUMO junction-what's your function?
-
Kerscher O. SUMO junction-what's your function?. EMBO Rep. 2007, 8:550-555.
-
(2007)
EMBO Rep.
, vol.8
, pp. 550-555
-
-
Kerscher, O.1
-
57
-
-
0030790695
-
P47 is a cofactor for p97-mediated membrane fusion
-
Kondo H., Rabouille C., Newman R., Levine T.P., Pappin D., Freemont P., Warren G. p47 is a cofactor for p97-mediated membrane fusion. Nature 1997, 388:75-78.
-
(1997)
Nature
, vol.388
, pp. 75-78
-
-
Kondo, H.1
Rabouille, C.2
Newman, R.3
Levine, T.P.4
Pappin, D.5
Freemont, P.6
Warren, G.7
-
58
-
-
0038487228
-
Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains
-
Ye Y., Meyer H.H., Rapoport T.A. Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. J. Cell Biol. 2003, 162:71-84.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 71-84
-
-
Ye, Y.1
Meyer, H.H.2
Rapoport, T.A.3
-
59
-
-
84865602944
-
Growing sphere of influence: Cdc48/p97 orchestrates ubiquitin-dependent extraction from chromatin
-
Dantuma N.P., Hoppe T. Growing sphere of influence: Cdc48/p97 orchestrates ubiquitin-dependent extraction from chromatin. Trends Cell Biol. 2012, 22:483-491.
-
(2012)
Trends Cell Biol.
, vol.22
, pp. 483-491
-
-
Dantuma, N.P.1
Hoppe, T.2
-
60
-
-
84899636473
-
Cdc48: a Swiss army knife of cell biology
-
Baek G.H., Cheng H., Choe V., Bao X., Shao J., Luo S., Rao H. Cdc48: a Swiss army knife of cell biology. J. Amino Acids 2013, 2013:183421.
-
(2013)
J. Amino Acids
, vol.2013
, pp. 183421
-
-
Baek, G.H.1
Cheng, H.2
Choe, V.3
Bao, X.4
Shao, J.5
Luo, S.6
Rao, H.7
-
61
-
-
75349101096
-
Structural and functional implications of phosphorylation and acetylation in the regulation of the AAA+ protein p97
-
Ewens C.A., Kloppsteck P., Forster A., Zhang X., Freemont P.S. Structural and functional implications of phosphorylation and acetylation in the regulation of the AAA+ protein p97. Biochem. Cell Biol. 2010, 88:41-48.
-
(2010)
Biochem. Cell Biol.
, vol.88
, pp. 41-48
-
-
Ewens, C.A.1
Kloppsteck, P.2
Forster, A.3
Zhang, X.4
Freemont, P.S.5
-
62
-
-
39449116598
-
Roles of VCP in human neurodegenerative disorders
-
Kakizuka A. Roles of VCP in human neurodegenerative disorders. Biochem. Soc. Trans. 2008, 36:105-108.
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 105-108
-
-
Kakizuka, A.1
-
63
-
-
5144219680
-
Identification of a SUMO-binding motif that recognizes SUMO-modified proteins
-
Song J., Durrin L.K., Wilkinson T.A., Krontiris T.G., Chen Y. Identification of a SUMO-binding motif that recognizes SUMO-modified proteins. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:14373-14378.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 14373-14378
-
-
Song, J.1
Durrin, L.K.2
Wilkinson, T.A.3
Krontiris, T.G.4
Chen, Y.5
-
64
-
-
28844455305
-
Small ubiquitin-like modifier (SUMO) recognition of a SUMO binding motif: a reversal of the bound orientation
-
Song J., Zhang Z., Hu W., Chen Y. Small ubiquitin-like modifier (SUMO) recognition of a SUMO binding motif: a reversal of the bound orientation. J. Biol. Chem. 2005, 280:40122-40129.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40122-40129
-
-
Song, J.1
Zhang, Z.2
Hu, W.3
Chen, Y.4
-
65
-
-
55549086868
-
The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains
-
Winborn B.J., Travis S.M., Todi S.V., Scaglione K.M., Xu P., Williams A.J., Cohen R.E., Peng J., Paulson H.L. The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains. J. Biol. Chem. 2008, 283:26436-26443.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 26436-26443
-
-
Winborn, B.J.1
Travis, S.M.2
Todi, S.V.3
Scaglione, K.M.4
Xu, P.5
Williams, A.J.6
Cohen, R.E.7
Peng, J.8
Paulson, H.L.9
-
66
-
-
79958134700
-
Hierarchical binding of cofactors to the AAA ATPase p97
-
Hanzelmann P., Buchberger A., Schindelin H. Hierarchical binding of cofactors to the AAA ATPase p97. Structure 2011, 19:833-843.
-
(2011)
Structure
, vol.19
, pp. 833-843
-
-
Hanzelmann, P.1
Buchberger, A.2
Schindelin, H.3
|