Time-response evaluation by transcriptomics of methylmercury effects on neural differentiation of murine embryonic stem cells

Toxicological Sciences

Volumn 122, Issue 2, 2011, Pages 437-447

  Theunissen, Peter T ^a,b   Pennings, Jeroen L A ^a,b   Robinson, Joshua F ^a,b   Claessen, Sandra M H ^b   Kleinjans, Jos C S ^b   Piersma, Aldert H ^a,b,c  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Alternative test method; Embryonic stem cells; Methylmercury; Microarray Affymetrix; Neural differentiation; Toxicogenomics

Indexed keywords

METHYLMERCURY;

ANIMAL CELL; ARTICLE; BLASTOCYST; CONTROLLED STUDY; ECTODERM; EMBRYONIC STEM CELL; GENE CLUSTER; GENE EXPRESSION; GENOME; MOUSE; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NEUROTOXICITY; NONHUMAN; PLURIPOTENT STEM CELL; PRINCIPAL COMPONENT ANALYSIS; TRANSCRIPTOMICS;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYONIC STEM CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; METHYLMERCURY COMPOUNDS; MICE; NEURONS; RNA; TOXICITY TESTS; WNT SIGNALING PATHWAY;

ANIMALIA; MURINAE;

EID: 79960842301     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr134     Document Type: Article

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