Characterization of conserved toxicogenomic responses in chemically exposed hepatocytes across species and platforms

Environmental Health Perspectives

Volumn 124, Issue 3, 2016, Pages 313-320

  El Hachem, Nehme ^a,b   Grossmann, Patrick ^c,d   Blanchet Cohen, Alexis ^a   Bateman, Alain R ^e   Bouchard, Nicolas ^a,b   Archambault, Jacques ^a   Aerts, Hugo J W L ^c,d   Haibe Kains, Benjamin ^f,g  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e MCGILL UNIVERSITY   (Canada)

^f PRINCESS MARGARET HOSPITAL   (Canada)

^g UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BENZBROMARONE; BENZIODARONE; BROMOBENZENE; CARCINOGEN; CHLORPHENIRAMINE; CLOFIBRATE; COUMARIN; DIETHYLNITROSAMINE; ETHIONINE; FENOFIBRATE; FUROSEMIDE; GEMFIBROZIL; GLIBENCLAMIDE; IBUPROFEN; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; N (2 FLUORENYL)ACETAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; NOTCH RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PIRINIXIC ACID; PROTEIN KINASE B; SMAD PROTEIN; THIOACETAMIDE; TOLL LIKE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TUBERCULOSTATIC AGENT; UNINDEXED DRUG; POLLUTANT;

ANIMAL CELL; ARTICLE; CARCINOGENICITY; CHEMICAL STRESS; CONTROLLED STUDY; GENE EXPRESSION; GENE SET ENRICHMENT ANALYSIS; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INNATE IMMUNITY; LIPID METABOLISM; LIVER CARCINOGENESIS; LIVER CELL CULTURE; LIVER CIRRHOSIS; LIVER TOXICITY; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TOXICITY TESTING; ANIMAL; CELL CULTURE; CLUSTER ANALYSIS; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENETICS; LIVER; LIVER CELL; METABOLISM; POLLUTANT; REPRODUCIBILITY; SPECIES DIFFERENCE; TOXICITY;

ANIMALS; CELLS, CULTURED; CLUSTER ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEPATOCYTES; HUMANS; LIVER; RATS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; TRANSCRIPTION, GENETIC;

EID: 84959297329     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1409157     Document Type: Article

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