Genomic allergen rapid detection in-house validation-A proof of concept

Toxicological Sciences

Volumn 139, Issue 2, 2014, Pages 362-370

  Johansson, Henrik ^a   Rydnert, Frida ^a   Kühnl, Jochen ^b   Schepky, Andreas ^b   Borrebaeck, Carl ^a   Lindstedt, Malin ^a  

^a LUND UNIVERSITY   (Sweden)

^b BEIERSDORF AG   (Germany)

Author keywords

Allergic contact dermatitis; Chemical sensitizers; GARD; In vitro assay; Predictive assay; Skin sensitization

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 2 BROMO 2 BROMOMETHYLGLUTARONITRILE; 2 MERCAPTOBENZOTHIAZOLE; 4 NITROBENZYLBROMIDE; ALLERGEN; BENZALKONIUM CHLORIDE; BENZOIC ACID; BIOLOGICAL MARKER; CHLOROBENZENE; CINNAMALDEHYDE; DIPHENCYPRONE; DODECYL SULFATE; DODECYL SULFATE SODIUM; HEXANE; HYDROQUINONE; HYDROXYCITRONELLAL; LACTIC ACID; MALEIC ACID DIETHYL ESTER; MENTHOL; PHENYLACETALDEHYDE; PINANEDIOL; SALICYLIC ACID; TAXIFOLIN; THIRAM; UNCLASSIFIED DRUG; XYLENE;

ACCURACY; ARTICLE; BONE MARROW CULTURE; CELL PROTECTION; CYTOTOXICITY; DIAGNOSTIC TEST ACCURACY STUDY; GENE EXPRESSION; HUMAN; IN VITRO STUDY; SENSITIVITY AND SPECIFICITY; SKIN SENSITIZATION; SUPPORT VECTOR MACHINE; ANIMAL TESTING ALTERNATIVE; BIOASSAY; CELL SURVIVAL; DERMATITIS, ALLERGIC CONTACT; DRUG EFFECTS; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; PREDICTIVE VALUE; PRINCIPAL COMPONENT ANALYSIS; REPRODUCIBILITY; TOXICITY; TUMOR CELL LINE;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; BIOLOGICAL ASSAY; BIOLOGICAL MARKERS; CELL LINE, TUMOR; CELL SURVIVAL; DERMATITIS, ALLERGIC CONTACT; HUMANS; PREDICTIVE VALUE OF TESTS; PRINCIPAL COMPONENT ANALYSIS; REPRODUCIBILITY OF RESULTS; SUPPORT VECTOR MACHINES; TRANSCRIPTION, GENETIC;

EID: 84899925111     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu046     Document Type: Article

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