MicroRNA-181b improves glucose homeostasis and insulin sensitivity by regulating endothelial function in white adipose tissue

Circulation Research

Volumn 118, Issue 5, 2016, Pages 810-821

  Sun, Xinghui ^a   Lin, Jibin ^a,b   Zhang, Yu ^c   Kang, Sona ^d,f   Belkin, Nathan ^a   Wara, Akm K ^a   Icli, Basak ^a   Hamburg, Naomi M ^e   Li, Dazhu ^b   Feinberg, Mark W ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adipose tissue; Endothelial cells; Insulin resistance; MicroRNA; Obesity; PHLPP2

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; MICRORNA; MICRORNA 181B; NITRIC OXIDE; PHOSPHOPROTEIN PHOSPHATASE; PLECKSTRIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; GLUCOSE BLOOD LEVEL; MIRN181 MICRORNA, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DIABETIC PATIENT; DRUG DELIVERY SYSTEM; ENDOTHELIUM CELL; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORT; HUMAN; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; MACROPHAGE; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; WHITE ADIPOSE TISSUE; ADVERSE EFFECTS; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; LIPID DIET; MALE; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; UMBILICAL VEIN ENDOTHELIAL CELL;

ADIPOSE TISSUE, WHITE; ANIMALS; BLOOD GLUCOSE; CELLS, CULTURED; DIET, HIGH-FAT; ENDOTHELIAL CELLS; HOMEOSTASIS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; MICRORNAS;

EID: 84954356949     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.115.308166     Document Type: Article

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