Liver sinusoidal endothelial cells link hyperinsulinemia to hepatic insulin resistance

Diabetes

Volumn 62, Issue 5, 2013, Pages 1478-1489

  Tsuchiya, Kyoichiro ^a   Accili, Domenico ^a  

^a Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRANSCRIPTION FACTOR FOXO; TYROSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; GAIN OF FUNCTION MUTATION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; HEPATIC INSULIN RESISTANCE; HYPERINSULINEMIA; INSULIN RESISTANCE; LIPID DIET; LIVER CELL; LIVER SINUSOID; LIVER SINUSOIDAL ENDOTHELIAL CELL; MALE; MOUSE; NITRATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HEPATOCYTES; HYPERINSULINISM; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; LIVER; MALE; MICE; MICE, KNOCKOUT; NITRIC OXIDE; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84876567932     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-1296     Document Type: Article

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