Reduced vascular nitric oxide-cgmp signaling contributes to adipose tissue inflammation during high-fat feeding

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 12, 2011, Pages 2827-2835

  Handa, Priya ^a   Tateya, Sanshiro ^a   Rizzo, Norma O ^a   Cheng, Andrew M ^a   Morgan Stevenson, Vicki ^a   Han, Chang Yeop ^a   Clowes, Alexander W ^b   Daum, Guenter ^b   O'Brien, Kevin D ^a   Schwartz, Michael W ^a   Chait, Alan ^a   Kim, Francis ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

adipose; endothelium; inflammation; nitric oxide

Indexed keywords

CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; SILDENAFIL; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; VASODILATOR STIMULATED PHOSPHOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATTENUATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; INSULIN RESISTANCE; LIPID DIET; LOW FAT DIET; MACROPHAGE; MALE; MOUSE; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADIPOSE TISSUE; ANIMALS; CELL ADHESION MOLECULES; CYCLIC GMP; DIETARY FATS; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; INFLAMMATION; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OBESITY; PHOSPHODIESTERASE 5 INHIBITORS; PHOSPHOPROTEINS; PHOSPHORYLATION; PIPERAZINES; PURINES; SIGNAL TRANSDUCTION; SULFONES;

EID: 81755166370     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.111.236554     Document Type: Article

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