FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis

Cell Metabolism

Volumn 15, Issue 3, 2012, Pages 372-381

  Tsuchiya, Kyoichiro ^a   Tanaka, Jun ^b   Shuiqing, Yu ^a   Welch, Carrie L ^a   Depinho, Ronald A ^c   Tabas, Ira ^a   Tall, Alan R ^a   Goldberg, Ira J ^a   Accili, Domenico ^a  

^a Columbia University ^*  (United States)

^b DAIICHI SANKYO CO   (Japan)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; LOW DENSITY LIPOPROTEIN RECEPTOR; NITRIC OXIDE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR FOXO;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL AGING; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE DELETION; GENETIC CODE; INSULIN RESISTANCE; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM;

ANIMALS; ATHEROSCLEROSIS; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; FORKHEAD TRANSCRIPTION FACTORS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT;

MUS;

EID: 84858066279     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2012.01.018     Document Type: Article

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