Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake

Nature Communications

Volumn 7, Issue , 2016, Pages

  Nakajima, Ken Ichiro ^a,b   Cui, Zhenzhong ^a   Li, Chia ^a   Meister, Jaroslawna ^a   Cui, Yinghong ^a   Fu, Ou ^b   Smith, Adam S ^c   Jain, Shalini ^a   Lowell, Bradford B ^d   Krashes, Michael J ^a   Wess, Jürgen ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; AGOUTI RELATED PROTEIN; ANOREXIGENIC AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENHANCED GREEN FLUORESCENT PROTEIN; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; KENPAULLONE; KRUPPEL LIKE FACTOR 4; N2 DIPHENYLACETYL N (4 UREIDOMETHYLBENZYL)ARGININAMIDE; NEUROPEPTIDE Y; PROTEIN C FOS; VESICULAR INHIBITORY AMINO ACID TRANSPORTER; CREB1 PROTEIN, MOUSE; KRUPPEL LIKE FACTOR; MESSENGER RNA; PHOSPHOPROTEIN;

BIOCHEMISTRY; BRAIN; FOOD INTAKE; PEPTIDE; SIGNALING;

4 AMINOBUTYRIC ACID RELEASE; ALLELE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; FEEDING; FLUORESCENCE; FOOD INTAKE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HYPOTHALAMIC SLICE; HYPOTHALAMUS; MALE; MEMBRANE STEADY POTENTIAL; MOUSE; NERVE CELL; NONHUMAN; OBESITY; PHENOTYPE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WHOLE CELL PATCH CLAMP; WILD TYPE; ANIMAL; CYTOLOGY; EATING; GENETICS; HEK293 CELL LINE; IMMUNOHISTOCHEMISTRY; METABOLISM; PATCH CLAMP TECHNIQUE;

AGOUTI;

AGOUTI-RELATED PROTEIN; ANIMALS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; EATING; GAMMA-AMINOBUTYRIC ACID; HEK293 CELLS; HUMANS; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; NEURONS; NEUROPEPTIDE Y; PATCH-CLAMP TECHNIQUES; PHOSPHOPROTEINS; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84953932017     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10268     Document Type: Article

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