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Volumn 76, Issue 1, 2016, Pages 1-12

Combined Angiotensin Receptor Modulation in the Management of Cardio-Metabolic Disorders

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN 2 RECEPTOR AGONIST; ANGIOTENSIN RECEPTOR; IRBESARTAN; LOSARTAN; N(G) NITROARGININE METHYL ESTER; NICOTINOYLTYROSYL(N BENZYLOXYCARBONYLARGINYL)LYSYLHISTIDYLPROLYLISOLEUCINE; RAMIPRIL; TELMISARTAN; UNCLASSIFIED DRUG; VALSARTAN;

EID: 84952982273     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.1007/s40265-015-0509-4     Document Type: Article
Times cited : (29)

References (118)
  • 2
    • 31744447164 scopus 로고    scopus 로고
    • How to best define the metabolic syndrome
    • 16448987
    • Magliano DJ, Shaw JE, Zimmet PZ. How to best define the metabolic syndrome. Ann Med. 2006;38:34-41.
    • (2006) Ann Med. , vol.38 , pp. 34-41
    • Magliano, D.J.1    Shaw, J.E.2    Zimmet, P.Z.3
  • 4
    • 0042532283 scopus 로고    scopus 로고
    • Estimated number of adults with prediabetes in the US in 2000: Opportunities for prevention
    • 12610015
    • Benjamin SM, Valdez R, Geiss LS, Rolka DB, Narayan KM. Estimated number of adults with prediabetes in the US in 2000: opportunities for prevention. Diabetes Care. 2003;26:645-9.
    • (2003) Diabetes Care. , vol.26 , pp. 645-649
    • Benjamin, S.M.1    Valdez, R.2    Geiss, L.S.3    Rolka, D.B.4    Narayan, K.M.5
  • 6
    • 0034524875 scopus 로고    scopus 로고
    • Effects of inhibition of the renin-angiotensin system on the cardiovascular actions of insulin
    • 11220351
    • Katovich MJ, Pachori A. Effects of inhibition of the renin-angiotensin system on the cardiovascular actions of insulin. Diabetes Obes Metab. 2000;2(1):3-14.
    • (2000) Diabetes Obes Metab. , vol.2 , Issue.1 , pp. 3-14
    • Katovich, M.J.1    Pachori, A.2
  • 7
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • 20148674
    • Olefsky JM, Glass CK. Macrophages, inflammation, and insulin resistance. Annu Rev Physiol. 2010;72:219-46.
    • (2010) Annu Rev Physiol. , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 8
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • 17167474
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature. 2006;444(7121):860-7.
    • (2006) Nature. , vol.444 , Issue.7121 , pp. 860-867
    • Hotamisligil, G.S.1
  • 9
    • 0033537013 scopus 로고    scopus 로고
    • Elevated C-reactive protein levels in overweight and obese adults
    • 10591334
    • Visser M, Bouter LM, McQuillan GM, Wener MH, Harris TB. Elevated C-reactive protein levels in overweight and obese adults. JAMA. 1999;282(22):2131-5.
    • (1999) JAMA , vol.282 , Issue.22 , pp. 2131-2135
    • Visser, M.1    Bouter, L.M.2    McQuillan, G.M.3    Wener, M.H.4    Harris, T.B.5
  • 10
    • 0031762908 scopus 로고    scopus 로고
    • Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: Depot difference and regulation by glucocorticoid
    • 9506738
    • Fried SK, Bunkin DA, Greenberg AS. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab. 1998;83(3):847-50.
    • (1998) J Clin Endocrinol Metab. , vol.83 , Issue.3 , pp. 847-850
    • Fried, S.K.1    Bunkin, D.A.2    Greenberg, A.S.3
  • 11
    • 0037840403 scopus 로고    scopus 로고
    • Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: A randomized trial
    • 12684358
    • Esposito K, Pontillo A, Di Palo C, Giugliano G, Masella M, Marfella R, Giugliano D. Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. JAMA. 2003;289(14):1799-804.
    • (2003) JAMA. , vol.289 , Issue.14 , pp. 1799-1804
    • Esposito, K.1    Pontillo, A.2    Di Palo, C.3    Giugliano, G.4    Masella, M.5    Marfella, R.6    Giugliano, D.7
  • 14
    • 79151484704 scopus 로고    scopus 로고
    • Adipokines in inflammation and metabolic disease
    • 21252989 3518031
    • Ouchi N, Parker JL, Lugus JJ, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol. 2011;11(2):85-97.
    • (2011) Nat Rev Immunol. , vol.11 , Issue.2 , pp. 85-97
    • Ouchi, N.1    Parker, J.L.2    Lugus, J.J.3    Walsh, K.4
  • 15
    • 0033538569 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways
    • 10391939
    • Huttunen HJ, Fages C, Rauvala H. Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways. J Biol Chem. 1999;274(28):19919-24.
    • (1999) J Biol Chem. , vol.274 , Issue.28 , pp. 19919-19924
    • Huttunen, H.J.1    Fages, C.2    Rauvala, H.3
  • 18
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
    • 9732873
    • Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature. 1998;394(6696):897-901.
    • (1998) Nature. , vol.394 , Issue.6696 , pp. 897-901
    • Lord, G.M.1    Matarese, G.2    Howard, J.K.3    Baker, R.J.4    Bloom, S.R.5    Lechler, R.I.6
  • 19
    • 0033602850 scopus 로고    scopus 로고
    • Human leptin stimulates proliferation and activation of human circulating monocytes
    • 10357875
    • Santos-Alvarez J, Goberna R, Sánchez-Margalet V. Human leptin stimulates proliferation and activation of human circulating monocytes. Cell Immunol. 1999;194(1):6-11.
    • (1999) Cell Immunol. , vol.194 , Issue.1 , pp. 6-11
    • Santos-Alvarez, J.1    Goberna, R.2    Sánchez-Margalet, V.3
  • 20
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • 9796811
    • Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature. 1998;395(6704):763-70.
    • (1998) Nature. , vol.395 , Issue.6704 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 22
    • 67649668789 scopus 로고    scopus 로고
    • Transcriptional integration of TLR2 and TLR4 signaling at the NCoR depression checkpoint
    • 19595715 2759189
    • Huang W, Ghisletti S, Perissi V, Rosenfeld MG, Glass CK. Transcriptional integration of TLR2 and TLR4 signaling at the NCoR depression checkpoint. Mol Cell. 2009;35:48-57.
    • (2009) Mol Cell. , vol.35 , pp. 48-57
    • Huang, W.1    Ghisletti, S.2    Perissi, V.3    Rosenfeld, M.G.4    Glass, C.K.5
  • 23
    • 0031733280 scopus 로고    scopus 로고
    • Human adipose tissue expresses angiotensinogen and enzymes required for its conversion to angiotensin II
    • 9814470
    • Karlsson C, Lindell K, Ottosson M, Sjöström L, Carlsson B, Carlsson LM. Human adipose tissue expresses angiotensinogen and enzymes required for its conversion to angiotensin II. J Clin Endocrinol Metab. 1998;83(11):3925-9.
    • (1998) J Clin Endocrinol Metab. , vol.83 , Issue.11 , pp. 3925-3929
    • Karlsson, C.1    Lindell, K.2    Ottosson, M.3    Sjöström, L.4    Carlsson, B.5    Carlsson, L.M.6
  • 26
    • 0033824138 scopus 로고    scopus 로고
    • International union of pharmacology. XXIII. the angiotensin II receptors
    • 10977869
    • de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T. International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev. 2000;52(3):415-72.
    • (2000) Pharmacol Rev. , vol.52 , Issue.3 , pp. 415-472
    • De Gasparo, M.1    Catt, K.J.2    Inagami, T.3    Wright, J.W.4    Unger, T.5
  • 27
    • 33748147006 scopus 로고    scopus 로고
    • Thiazide diuretics, potassium, and the development of diabetes: A quantitative review
    • 16801488
    • Zillich AJ, Garg J, Basu S, Bakris GL, Carter BL. Thiazide diuretics, potassium, and the development of diabetes: a quantitative review. Hypertension. 2006;48(2):219-24.
    • (2006) Hypertension. , vol.48 , Issue.2 , pp. 219-224
    • Zillich, A.J.1    Garg, J.2    Basu, S.3    Bakris, G.L.4    Carter, B.L.5
  • 28
    • 2342525336 scopus 로고    scopus 로고
    • Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice
    • 15037562
    • Shiuchi T, Iwai M, Li HS, Wu L, Min LJ, Li JM, Okumura M, Cui TX, Horiuchi M. Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice. Hypertension. 2004;43(5):1003-10.
    • (2004) Hypertension. , vol.43 , Issue.5 , pp. 1003-1010
    • Shiuchi, T.1    Iwai, M.2    Li, H.S.3    Wu, L.4    Min, L.J.5    Li, J.M.6    Okumura, M.7    Cui, T.X.8    Horiuchi, M.9
  • 30
    • 0030956371 scopus 로고    scopus 로고
    • Angiotensin II increases lipogenesis in 3T3-L1 and human adipose cells
    • 9075710
    • Jones BH, Standridge MK, Moustaid N. Angiotensin II increases lipogenesis in 3T3-L1 and human adipose cells. Endocrinology. 1997;138(4):1512-9.
    • (1997) Endocrinology. , vol.138 , Issue.4 , pp. 1512-1519
    • Jones, B.H.1    Standridge, M.K.2    Moustaid, N.3
  • 32
    • 34047154582 scopus 로고    scopus 로고
    • The problem of obesity: Is there a role for antagonists of the renin-angiotensin system?
    • 17392133
    • Weisinger RS, Begg DP, Chen N, Jois M, Mathai ML, Sinclair AJ. The problem of obesity: is there a role for antagonists of the renin-angiotensin system? Asia Pac J Clin Nutr. 2007;16(Suppl 1):359-67.
    • (2007) Asia Pac J Clin Nutr. , vol.16 , Issue.1 , pp. 359-367
    • Weisinger, R.S.1    Begg, D.P.2    Chen, N.3    Jois, M.4    Mathai, M.L.5    Sinclair, A.J.6
  • 33
    • 0036266179 scopus 로고    scopus 로고
    • Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors
    • 12031955
    • Janke J, Engeli S, Gorzelniak K, Luft FC, Sharma AM. Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors. Diabetes. 2002;51(6):1699-707.
    • (2002) Diabetes. , vol.51 , Issue.6 , pp. 1699-1707
    • Janke, J.1    Engeli, S.2    Gorzelniak, K.3    Luft, F.C.4    Sharma, A.M.5
  • 35
    • 0035988844 scopus 로고    scopus 로고
    • Angiotensin II as a pro-inflammatory mediator
    • 12090726
    • Phillips MI, Kagiyama S. Angiotensin II as a pro-inflammatory mediator. Curr Opin Investig Drugs. 2002;3(4):569-77.
    • (2002) Curr Opin Investig Drugs. , vol.3 , Issue.4 , pp. 569-577
    • Phillips, M.I.1    Kagiyama, S.2
  • 37
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
    • The SOLVD Investigators
    • The SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med. 1991;325(5):293-302.
    • (1991) N Engl J Med. , vol.325 , Issue.5 , pp. 293-302
  • 39
    • 0033589756 scopus 로고    scopus 로고
    • Randomised trial of old and new antihypertensive drugs in elderly patients: Cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study
    • 10577635
    • Hansson L, Lindholm LH, Ekbom T, Dahlöf B, Lanke J, Scherstén B, Wester PO, Hedner T, de Faire U. Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study. Lancet. 1999;354:1751-6.
    • (1999) Lancet. , vol.354 , pp. 1751-1756
    • Hansson, L.1    Lindholm, L.H.2    Ekbom, T.3    Dahlöf, B.4    Lanke, J.5    Scherstén, B.6    Wester, P.O.7    Hedner, T.8    De Faire, U.9
  • 40
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. the Heart Outcomes Prevention Evaluation Study Investigators
    • 10639539
    • Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342(3):145-53.
    • (2000) N Engl J Med. , vol.342 , Issue.3 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 41
    • 0042410539 scopus 로고    scopus 로고
    • Pocock S; CHARM Investigators and Committees. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: The CHARM-Overall programme
    • 13678868
    • Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ, Michelson EL, Olofsson B, Ostergren J, Yusuf S. Pocock S; CHARM Investigators and Committees. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet. 2003;362(9386):759-66.
    • (2003) Lancet. , vol.362 , Issue.9386 , pp. 759-766
    • Pfeffer, M.A.1    Swedberg, K.2    Granger, C.B.3    Held, P.4    McMurray, J.J.5    Michelson, E.L.6    Olofsson, B.7    Ostergren, J.8    Yusuf, S.9
  • 46
    • 33846294746 scopus 로고    scopus 로고
    • Incident diabetes in clinical trials of antihypertensive drugs: A network meta-analysis
    • 17240286
    • Elliott WJ, Meyer PM. Incident diabetes in clinical trials of antihypertensive drugs: a network meta-analysis. Lancet. 2007;369(9557):201-7.
    • (2007) Lancet. , vol.369 , Issue.9557 , pp. 201-207
    • Elliott, W.J.1    Meyer, P.M.2
  • 47
    • 0027517659 scopus 로고
    • The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. the Collaborative Study Group
    • 8413456
    • Lewis EJ, Hunsicker LG, Bain RP, Rohde RD. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group. N Engl J Med. 1993;329(20):1456-62.
    • (1993) N Engl J Med. , vol.329 , Issue.20 , pp. 1456-1462
    • Lewis, E.J.1    Hunsicker, L.G.2    Bain, R.P.3    Rohde, R.D.4
  • 48
    • 0035922444 scopus 로고    scopus 로고
    • The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
    • Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria Study Group 11565519
    • Parving HH, Lehnert H, Bröchner-Mortensen J, Gomis R, Andersen S, Arner P, Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria Study Group. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med. 2001;345(12):870-8.
    • (2001) N Engl J Med. , vol.345 , Issue.12 , pp. 870-878
    • Parving, H.H.1    Lehnert, H.2    Bröchner-Mortensen, J.3    Gomis, R.4    Andersen, S.5    Arner, P.6
  • 50
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Collaborative Study Group 11565517
    • Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, Ritz E, Atkins RC, Rohde R, Raz I, Collaborative Study Group. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med. 2001;345(12):851-60.
    • (2001) N Engl J Med. , vol.345 , Issue.12 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3    Berl, T.4    Pohl, M.A.5    Lewis, J.B.6    Ritz, E.7    Atkins, R.C.8    Rohde, R.9    Raz, I.10
  • 51
    • 67649659279 scopus 로고    scopus 로고
    • Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: Three randomized trials
    • W3-4
    • Bilous R, Chaturvedi N, Sjølie AK, Fuller J, Klein R, Orchard T, Porta M, Parving HH. Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes: three randomized trials. Ann Intern Med. 2009;151(1):11-20, W3-4.
    • (2009) Ann Intern Med. , vol.151 , Issue.1 , pp. 11-20
    • Bilous, R.C.1
  • 54
    • 34248178511 scopus 로고    scopus 로고
    • Albuminuria is a target for renoprotective therapy independent from blood pressure in patients with type 2 diabetic nephropathy: Post hoc analysis from the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial
    • 17409317
    • Eijkelkamp WB, Zhang Z, Remuzzi G, Parving HH, Cooper ME, Keane WF, Shahinfar S, Gleim GW, Weir MR, Brenner BM, de Zeeuw D. Albuminuria is a target for renoprotective therapy independent from blood pressure in patients with type 2 diabetic nephropathy: post hoc analysis from the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial. J Am Soc Nephrol. 2007;18(5):1540-6.
    • (2007) J Am Soc Nephrol. , vol.18 , Issue.5 , pp. 1540-1546
    • Eijkelkamp, W.B.1    Zhang, Z.2    Remuzzi, G.3    Parving, H.H.4    Cooper, M.E.5    Keane, W.F.6    Shahinfar, S.7    Gleim, G.W.8    Weir, M.R.9    Brenner, B.M.10    De Zeeuw, D.11
  • 55
    • 70349980161 scopus 로고    scopus 로고
    • Next generation multifunctional angiotensin receptor blockers
    • 19713966
    • Kurtz TW, Klein U. Next generation multifunctional angiotensin receptor blockers. Hypertens Res. 2009;32(10):826-34.
    • (2009) Hypertens Res. , vol.32 , Issue.10 , pp. 826-834
    • Kurtz, T.W.1    Klein, U.2
  • 56
    • 2442451618 scopus 로고    scopus 로고
    • Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity
    • 15117841
    • Schupp M, Janke J, Clasen R, Unger T, Kintscher U. Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity. Circulation. 2004;109(17):2054-7.
    • (2004) Circulation. , vol.109 , Issue.17 , pp. 2054-2057
    • Schupp, M.1    Janke, J.2    Clasen, R.3    Unger, T.4    Kintscher, U.5
  • 57
    • 33644672013 scopus 로고    scopus 로고
    • Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity
    • 16306360
    • Schupp M, Clemenz M, Gineste R, Witt H, Janke J, Helleboid S, Hennuyer N, Ruiz P, Unger T, Staels B, Kintscher U. Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity. Diabetes. 2005;54(12):3442-52.
    • (2005) Diabetes. , vol.54 , Issue.12 , pp. 3442-3452
    • Schupp, M.1    Clemenz, M.2    Gineste, R.3    Witt, H.4    Janke, J.5    Helleboid, S.6    Hennuyer, N.7    Ruiz, P.8    Unger, T.9    Staels, B.10    Kintscher, U.11
  • 58
    • 33644983016 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor gamma activity by losartan metabolites
    • 16365190
    • Schupp M, Lee LD, Frost N, Umbreen S, Schmidt B, Unger T, Kintscher U. Regulation of peroxisome proliferator-activated receptor gamma activity by losartan metabolites. Hypertension. 2006;47(3):586-9.
    • (2006) Hypertension. , vol.47 , Issue.3 , pp. 586-589
    • Schupp, M.1    Lee, L.D.2    Frost, N.3    Umbreen, S.4    Schmidt, B.5    Unger, T.6    Kintscher, U.7
  • 59
    • 48449106424 scopus 로고    scopus 로고
    • Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan
    • 18184928
    • Clemenz M, Frost N, Schupp M, Caron S, Foryst-Ludwig A, Böhm C, Hartge M, Gust R, Staels B, Unger T, Kintscher U. Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan. Diabetes. 2008;57(5):1405-13.
    • (2008) Diabetes. , vol.57 , Issue.5 , pp. 1405-1413
    • Clemenz, M.1    Frost, N.2    Schupp, M.3    Caron, S.4    Foryst-Ludwig, A.5    Böhm, C.6    Hartge, M.7    Gust, R.8    Staels, B.9    Unger, T.10    Kintscher, U.11
  • 62
    • 80053574174 scopus 로고    scopus 로고
    • High-dose treatment with telmisartan induces monocytic peroxisome proliferator-activated receptor-γ target genes in patients with the metabolic syndrome
    • 21876071
    • Bähr IN, Tretter P, Krüger J, Stark RG, Schimkus J, Unger T, Kappert K, Scholze J, Parhofer KG, Kintscher U. High-dose treatment with telmisartan induces monocytic peroxisome proliferator-activated receptor-γ target genes in patients with the metabolic syndrome. Hypertension. 2011;58(4):725-32.
    • (2011) Hypertension. , vol.58 , Issue.4 , pp. 725-732
    • Bähr, I.N.1    Tretter, P.2    Krüger, J.3    Stark, R.G.4    Schimkus, J.5    Unger, T.6    Kappert, K.7    Scholze, J.8    Parhofer, K.G.9    Kintscher, U.10
  • 65
    • 54449092429 scopus 로고    scopus 로고
    • Inhibiting angiotensin type 1 receptors as a target for diabetes
    • 18781824
    • Kintscher U, Foryst-Ludwig A, Unger T. Inhibiting angiotensin type 1 receptors as a target for diabetes. Expert Opin Ther Targets. 2008;12(10):1257-63.
    • (2008) Expert Opin Ther Targets. , vol.12 , Issue.10 , pp. 1257-1263
    • Kintscher, U.1    Foryst-Ludwig, A.2    Unger, T.3
  • 66
    • 84928633234 scopus 로고    scopus 로고
    • New developments in the pharmacological treatment of hypertension: Dead-end or a glimmer at the horizon?
    • 25893478
    • Paulis L, Rajkovicova R, Simko F. New developments in the pharmacological treatment of hypertension: dead-end or a glimmer at the horizon? Curr Hypertens Rep. 2015;17(6):557.
    • (2015) Curr Hypertens Rep. , vol.17 , Issue.6 , pp. 557
    • Paulis, L.1    Rajkovicova, R.2    Simko, F.3
  • 70
    • 84856120678 scopus 로고    scopus 로고
    • Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats
    • Rehman A, Leibowitz A, Yamamoto N, Rautureau Y, Paradis P, Schiffrin EL. Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats. Hypertension. 2012;59(2):485-92.
    • (2012) Hypertension. , vol.59 , Issue.2 , pp. 485-492
    • Rehman, A.1    Leibowitz, A.2    Yamamoto, N.3    Rautureau, Y.4    Paradis, P.5    Schiffrin, E.L.6
  • 73
    • 84894417555 scopus 로고    scopus 로고
    • Angiotensin type 2 receptor stimulation ameliorates left ventricular fibrosis and dysfunction via regulation of tissue inhibitor of matrix metalloproteinase 1/matrix metalloproteinase 9 axis and transforming growth factor β1 in the rat heart
    • 24379181
    • Lauer D, Slavic S, Sommerfeld M, Thöne-Reineke C, Sharkovska Y, Hallberg A, Dahlöf B, Kintscher U, Unger T, Steckelings UM, Kaschina E. Angiotensin type 2 receptor stimulation ameliorates left ventricular fibrosis and dysfunction via regulation of tissue inhibitor of matrix metalloproteinase 1/matrix metalloproteinase 9 axis and transforming growth factor β1 in the rat heart. Hypertension. 2014;63(3):e60-7.
    • (2014) Hypertension. , vol.63 , Issue.3 , pp. e60-e67
    • Lauer, D.1    Slavic, S.2    Sommerfeld, M.3    Thöne-Reineke, C.4    Sharkovska, Y.5    Hallberg, A.6    Dahlöf, B.7    Kintscher, U.8    Unger, T.9    Steckelings, U.M.10    Kaschina, E.11
  • 74
    • 84940689333 scopus 로고    scopus 로고
    • Hypotensive and sympathoinhibitory responses to selective central AT2 receptor stimulation in spontaneously hypertensive rats
    • 25655919
    • Brouwers S, Smolders I, Wainford RD, Dupont AG. Hypotensive and sympathoinhibitory responses to selective central AT2 receptor stimulation in spontaneously hypertensive rats. Clin Sci (Lond). 2015;129:81-92.
    • (2015) Clin Sci (Lond). , vol.129 , pp. 81-92
    • Brouwers, S.1    Smolders, I.2    Wainford, R.D.3    Dupont, A.G.4
  • 75
    • 84986902830 scopus 로고    scopus 로고
    • Activation of central angiotensin type 2 receptors by compound 21 improves arterial baroreflex sensitivity in rats with heart failure
    • 24687998 4229732
    • Gao J, Zucker IH, Gao L. Activation of central angiotensin type 2 receptors by compound 21 improves arterial baroreflex sensitivity in rats with heart failure. Am J Hypertens. 2014;27(10):1248-56.
    • (2014) Am J Hypertens. , vol.27 , Issue.10 , pp. 1248-1256
    • Gao, J.1    Zucker, I.H.2    Gao, L.3
  • 76
    • 0031611616 scopus 로고    scopus 로고
    • AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism
    • 9453327
    • Gohlke P, Pees C, Unger T. AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism. Hypertension. 1998;31(1 Pt 2):349-55.
    • (1998) Hypertension , vol.31 , Issue.1 , pp. 349-355
    • Gohlke, P.1    Pees, C.2    Unger, T.3
  • 77
    • 37549029151 scopus 로고    scopus 로고
    • Over-expression of angiotensin II type 2 receptor (agtr2) decreases collagen accumulation in atherosclerotic plaque
    • 18037370
    • Dandapat A, Hu CP, Chen J, Liu Y, Khan JA, Remeo F, et al. Over-expression of angiotensin II type 2 receptor (agtr2) decreases collagen accumulation in atherosclerotic plaque. Biochem Biophys Res Commun. 2008;366:871-7.
    • (2008) Biochem Biophys Res Commun. , vol.366 , pp. 871-877
    • Dandapat, A.1    Hu, C.P.2    Chen, J.3    Liu, Y.4    Khan, J.A.5    Remeo, F.6
  • 78
    • 0031708151 scopus 로고    scopus 로고
    • Role of AT1 and AT2 receptors in regulation of MAPKs and MKP-1 by ANG II in adult cardiac myocytes
    • 9724295
    • Fischer TA, Singh K, O'Hara DS, Kaye DM, Kelly RA. Role of AT1 and AT2 receptors in regulation of MAPKs and MKP-1 by ANG II in adult cardiac myocytes. Am J Physiol. 1998;275(3 Pt 2):H906-16.
    • (1998) Am J Physiol. , vol.275 , Issue.3 , pp. H906-H916
    • Fischer, T.A.1    Singh, K.2    O'Hara, D.S.3    Kaye, D.M.4    Kelly, R.A.5
  • 79
    • 0035955732 scopus 로고    scopus 로고
    • The angiotensin II AT2 receptor is an AT1 receptor antagonist
    • 11507095
    • AbdAlla S, Lother H, Abdel-tawab AM, Quitterer U. The angiotensin II AT2 receptor is an AT1 receptor antagonist. J Biol Chem. 2001;276(43):39721-6.
    • (2001) J Biol Chem. , vol.276 , Issue.43 , pp. 39721-39726
    • AbdAlla, S.1    Lother, H.2    Abdel-Tawab, A.M.3    Quitterer, U.4
  • 82
    • 84920528695 scopus 로고    scopus 로고
    • Angiotensin AT2 receptor stimulation is anti-inflammatory in lipopolysaccharide-activated THP-1 macrophages via increased interleukin-10 production
    • 25209104
    • Dhande I, Ma W, Hussain T. Angiotensin AT2 receptor stimulation is anti-inflammatory in lipopolysaccharide-activated THP-1 macrophages via increased interleukin-10 production. Hypertens Res. 2015;38(1):21-9.
    • (2015) Hypertens Res. , vol.38 , Issue.1 , pp. 21-29
    • Dhande, I.1    Ma, W.2    Hussain, T.3
  • 83
  • 85
    • 72949120143 scopus 로고    scopus 로고
    • Molecular mechanisms of the antagonistic action between AT1 and AT2 receptors
    • 19896468 3891515
    • Miura S, Matsuo Y, Kiya Y, Karnik SS, Saku K. Molecular mechanisms of the antagonistic action between AT1 and AT2 receptors. Biochem Biophys Res Commun. 2010;391(1):85-90.
    • (2010) Biochem Biophys Res Commun. , vol.391 , Issue.1 , pp. 85-90
    • Miura, S.1    Matsuo, Y.2    Kiya, Y.3    Karnik, S.S.4    Saku, K.5
  • 86
    • 63849254162 scopus 로고    scopus 로고
    • New insights into the regulation of angiotensin receptors
    • 19430334
    • Mogi M, Iwai M, Horiuchi M. New insights into the regulation of angiotensin receptors. Curr Opin Nephrol Hypertens. 2009;18(2):138-43.
    • (2009) Curr Opin Nephrol Hypertens. , vol.18 , Issue.2 , pp. 138-143
    • Mogi, M.1    Iwai, M.2    Horiuchi, M.3
  • 89
    • 84952978195 scopus 로고    scopus 로고
    • A glucose tolerance and insulin sensitivity is improved in obese mice by direct stimulation of angiotensin AT2-receptors
    • 30.9-2.10 La Colle sur Loup, Nice, France.
    • Wardat S, Iwai M, Horiuchi M, Dahlöf B, Hallberg A, Unger T, Kintscher U, Steckelings UM, Foryst-Ludwig. A glucose tolerance and insulin sensitivity is improved in obese mice by direct stimulation of angiotensin AT2-receptors, 16th annual meeting of the european council for cardiovascular research (ECCR) 30.9-2.10 2011 La Colle sur Loup, Nice, France.
    • (2011) 16th Annual Meeting of the European Council for Cardiovascular Research (ECCR)
    • Wardat, S.I.1
  • 90
    • 85019283804 scopus 로고    scopus 로고
    • TNF-α-mediated inflammatory response in adipocytes is attenuated by the direct activation of angiotensin II AT2-receptors
    • Wardat S, Kintscher U, Steckelings UM, Foryst-Ludwig A. TNF-α-mediated inflammatory response in adipocytes is attenuated by the direct activation of angiotensin II AT2-receptors. Hypertension. 2009;54(5):1179.
    • (2009) Hypertension , vol.54 , Issue.5 , pp. 1179
    • Wardat, S.1    Kintscher, U.2    Steckelings, U.M.3    Foryst-Ludwig, A.4
  • 91
    • 84887589373 scopus 로고    scopus 로고
    • Angiotensin type 2 receptor in pancreatic islets of adult rats: A novel insulinotropic mediator
    • 24085035 3840212
    • Shao C, Zucker IH, Gao L. Angiotensin type 2 receptor in pancreatic islets of adult rats: a novel insulinotropic mediator. Am J Physiol Endocrinol Metab. 2013;305(10):E1281-91.
    • (2013) Am J Physiol Endocrinol Metab. , vol.305 , Issue.10 , pp. E1281-E1291
    • Shao, C.1    Zucker, I.H.2    Gao, L.3
  • 92
    • 84896859922 scopus 로고    scopus 로고
    • Activation of angiotensin type 2 receptors partially ameliorates streptozotocin-induced diabetes in male rats by islet protection
    • 24302627 3929733
    • Shao C, Yu L, Gao L. Activation of angiotensin type 2 receptors partially ameliorates streptozotocin-induced diabetes in male rats by islet protection. Endocrinology. 2014;155(3):793-804.
    • (2014) Endocrinology. , vol.155 , Issue.3 , pp. 793-804
    • Shao, C.1    Yu, L.2    Gao, L.3
  • 93
    • 79551505061 scopus 로고    scopus 로고
    • 2 receptor stimulation inhibits early renal inflammation in renovascular hypertension
    • 21189405 3060557
    • 2 receptor stimulation inhibits early renal inflammation in renovascular hypertension. Hypertension. 2011;57(2):308-13.
    • (2011) Hypertension. , vol.57 , Issue.2 , pp. 308-313
    • Matavelli, L.C.1    Huang, J.2    Siragy, H.M.3
  • 95
    • 84939998893 scopus 로고    scopus 로고
    • A nonpeptide angiotensin II type 2 receptor agonist prevents renal inflammation in early diabetes
    • 25590749
    • Matavelli LC, Zatz R, Siragy HM. A nonpeptide angiotensin II type 2 receptor agonist prevents renal inflammation in early diabetes. J Cardiovasc Pharmacol. 2015;65(4):371-6.
    • (2015) J Cardiovasc Pharmacol. , vol.65 , Issue.4 , pp. 371-376
    • Matavelli, L.C.1    Zatz, R.2    Siragy, H.M.3
  • 97
    • 79954514695 scopus 로고    scopus 로고
    • Role of the angiotensin II AT2 receptor in inflammation and oxidative stress: Opposing effects in lean and obese Zucker rats
    • Sabuhi R1, Ali Q, Asghar M, Al-Zamily NR, Hussain T. Role of the angiotensin II AT2 receptor in inflammation and oxidative stress: opposing effects in lean and obese Zucker rats. Am J Physiol Renal Physiol. 2011;300(3):F700-6.
    • (2011) Am J Physiol Renal Physiol , vol.300 , Issue.3 , pp. F700-F706
    • Sabuhi, R.L.1    Ali, Q.2    Asghar, M.3    Al-Zamily, N.R.4    Hussain, T.5
  • 99
    • 84931098651 scopus 로고    scopus 로고
    • Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese Zucker rats
    • Ali Q, Patel SN, Hussain T. Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese Zucker rats. Am J Physiol Renal Physiol. 2015. doi: 10.1152/ajprenal.00002.2015.
    • (2015) Am J Physiol Renal Physiol
    • Ali, Q.1    Patel, S.N.2    Hussain, T.3
  • 100
    • 84886432625 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor-mediated and nitric oxide-dependent renal vasodilator response to compound 21 unmasked by angiotensin-converting enzyme inhibition in spontaneously hypertensive rats in vivo
    • 24041944
    • Brouwers S, Smolders I, Massie A, Dupont AG. Angiotensin II type 2 receptor-mediated and nitric oxide-dependent renal vasodilator response to compound 21 unmasked by angiotensin-converting enzyme inhibition in spontaneously hypertensive rats in vivo. Hypertension. 2013;62:920-6.
    • (2013) Hypertension. , vol.62 , pp. 920-926
    • Brouwers, S.1    Smolders, I.2    Massie, A.3    Dupont, A.G.4
  • 101
    • 84904514343 scopus 로고    scopus 로고
    • Angiotensin type 2 receptor stimulation increases renal function in female, but not male, spontaneously hypertensive rats
    • 24842923
    • Hilliard LM, Chow CL, Mirabito KM, Steckelings UM, Unger T, Widdop RE, Denton KM. Angiotensin type 2 receptor stimulation increases renal function in female, but not male, spontaneously hypertensive rats. Hypertension. 2014;64(2):378-83.
    • (2014) Hypertension. , vol.64 , Issue.2 , pp. 378-383
    • Hilliard, L.M.1    Chow, C.L.2    Mirabito, K.M.3    Steckelings, U.M.4    Unger, T.5    Widdop, R.E.6    Denton, K.M.7
  • 103
    • 77957558776 scopus 로고    scopus 로고
    • Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice
    • 20660625 3279528
    • Bindom SM, Hans CP, Xia H, Boulares AH, Lazartigues E. Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice. Diabetes. 2010;59(10):2540-8.
    • (2010) Diabetes. , vol.59 , Issue.10 , pp. 2540-2548
    • Bindom, S.M.1    Hans, C.P.2    Xia, H.3    Boulares, A.H.4    Lazartigues, E.5
  • 106
    • 0024581572 scopus 로고
    • Prostacyclin as a potent effector of adipose-cell differentiation
    • 2539085 1135593
    • Négrel R, Gaillard D, Ailhaud G. Prostacyclin as a potent effector of adipose-cell differentiation. Biochem J. 1989;257(2):399-405.
    • (1989) Biochem J. , vol.257 , Issue.2 , pp. 399-405
    • Négrel, R.1    Gaillard, D.2    Ailhaud, G.3
  • 107
    • 0034627208 scopus 로고    scopus 로고
    • Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: The candesartan and lisinopril microalbuminuria (CALM) study
    • 11110735 27545
    • Mogensen CE, Neldam S, Tikkanen I, Oren S, Viskoper R, Watts RW, Cooper ME. Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the candesartan and lisinopril microalbuminuria (CALM) study. BMJ. 2000;321(7274):1440-4.
    • (2000) BMJ. , vol.321 , Issue.7274 , pp. 1440-1444
    • Mogensen, C.E.1    Neldam, S.2    Tikkanen, I.3    Oren, S.4    Viskoper, R.5    Watts, R.W.6    Cooper, M.E.7
  • 108
    • 34648820103 scopus 로고    scopus 로고
    • Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: Results of the IMPROVE trial
    • 17667984
    • Bakris GL, Ruilope L, Locatelli F, Ptaszynska A, Pieske B, de Champlain J, Weber MA, Raz I. Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: results of the IMPROVE trial. Kidney Int. 2007;72(7):879-85.
    • (2007) Kidney Int. , vol.72 , Issue.7 , pp. 879-885
    • Bakris, G.L.1    Ruilope, L.2    Locatelli, F.3    Ptaszynska, A.4    Pieske, B.5    De Champlain, J.6    Weber, M.A.7    Raz, I.8
  • 109
    • 44849114597 scopus 로고    scopus 로고
    • Aliskiren combined with losartan in type 2 diabetes and nephropathy
    • AVOID Study Investigators 18525041
    • Parving HH, Persson F, Lewis JB, Lewis EJ, Hollenberg NK, AVOID Study Investigators. Aliskiren combined with losartan in type 2 diabetes and nephropathy. N Engl J Med. 2008;358(23):2433-46.
    • (2008) N Engl J Med. , vol.358 , Issue.23 , pp. 2433-2446
    • Parving, H.H.1    Persson, F.2    Lewis, J.B.3    Lewis, E.J.4    Hollenberg, N.K.5
  • 110
    • 79957840666 scopus 로고    scopus 로고
    • Aliskiren in combination with losartan reduces albuminuria independent of baseline blood pressure in patients with type 2 diabetes and nephropathy
    • 21350110 3087767
    • Persson F, Lewis JB, Lewis EJ, Rossing P, Hollenberg NK, Parving HH. Aliskiren in combination with losartan reduces albuminuria independent of baseline blood pressure in patients with type 2 diabetes and nephropathy. Clin J Am Soc Nephrol. 2011;6(5):1025-31.
    • (2011) Clin J Am Soc Nephrol. , vol.6 , Issue.5 , pp. 1025-1031
    • Persson, F.1    Lewis, J.B.2    Lewis, E.J.3    Rossing, P.4    Hollenberg, N.K.5    Parving, H.H.6
  • 113
    • 84874318834 scopus 로고    scopus 로고
    • Efficacy and safety of dual blockade of the renin-angiotensin system: Meta-analysis of randomised trials
    • 23358488 3556933
    • Makani H, Bangalore S, Desouza KA, Shah A, Messerli FH. Efficacy and safety of dual blockade of the renin-angiotensin system: meta-analysis of randomised trials. BMJ. 2013;346:f360.
    • (2013) BMJ. , vol.346 , pp. f360
    • Makani, H.1    Bangalore, S.2    Desouza, K.A.3    Shah, A.4    Messerli, F.H.5
  • 114
    • 84858680846 scopus 로고    scopus 로고
    • Inhibition of the renin-angiotensin-aldosterone system: Is there room for dual blockade in the cardiorenal continuum?
    • 22278139
    • Volpe M, Danser AH, Menard J, Waeber B, Mueller DN, Maggioni AP, Ruilope LM. Inhibition of the renin-angiotensin-aldosterone system: is there room for dual blockade in the cardiorenal continuum? J Hypertens. 2012;30(4):647-54.
    • (2012) J Hypertens. , vol.30 , Issue.4 , pp. 647-654
    • Volpe, M.1    Danser, A.H.2    Menard, J.3    Waeber, B.4    Mueller, D.N.5    Maggioni, A.P.6    Ruilope, L.M.7
  • 116
    • 77949557153 scopus 로고    scopus 로고
    • Prediction of cardiovascular events and all-cause mortality with arterial stiffness: A systematic review and meta-analysis
    • 20338492
    • Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol. 2010;55:1318-27.
    • (2010) J Am Coll Cardiol. , vol.55 , pp. 1318-1327
    • Vlachopoulos, C.1    Aznaouridis, K.2    Stefanadis, C.3
  • 117
    • 0035916234 scopus 로고    scopus 로고
    • Impact of aortic stiffness attenuation on survival of patients in end-stage renal failure
    • 11181474
    • Guerin AP, Blacher J, Pannier B, Marchais SJ, Safar ME, London GM. Impact of aortic stiffness attenuation on survival of patients in end-stage renal failure. Circulation. 2001;103:987-92.
    • (2001) Circulation. , vol.103 , pp. 987-992
    • Guerin, A.P.1    Blacher, J.2    Pannier, B.3    Marchais, S.J.4    Safar, M.E.5    London, G.M.6


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