메뉴 건너뛰기




Volumn 62, Issue 5, 2013, Pages 920-926

Angiotensin II type 2 receptor-mediated and nitric oxide-dependent renal vasodilator response to compound 21 unmasked by angiotensin-converting enzyme inhibition in spontaneously hypertensive rats in vivo

Author keywords

angiotensin II; blood pressure; compound 21; receptor angiotensin type 2; receptor, angiotensin type 1; renal circulation

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FENOLDOPAM; ICATIBANT; INDOMETACIN; N(G) METHYLARGININE; NITRIC OXIDE; PROSTAGLANDIN; VASODILATOR AGENT; BRADYKININ; DOPAMINE RECEPTOR STIMULATING AGENT; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; N-BUTYLOXYCARBONYL-3-(4-IMIDAZOL-1-YLMETHYLPHENYL)-5-ISOBUTYLTHIOPHENE-2-SULFONAMIDE; PYRIDINE DERIVATIVE; SULFONAMIDE; THIOPHENE DERIVATIVE;

EID: 84886432625     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.112.00762     Document Type: Article
Times cited : (34)

References (34)
  • 1
    • 0033824138 scopus 로고    scopus 로고
    • International union of pharmacology. XXIII. The angiotensin II receptors
    • de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T. International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev. 2000;52:415-472.
    • (2000) Pharmacol Rev , vol.52 , pp. 415-472
    • De Gasparo, M.1    Catt, K.J.2    Inagami, T.3    Wright, J.W.4    Unger, T.5
  • 4
    • 13144305024 scopus 로고    scopus 로고
    • Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats
    • Hakam AC, Hussain T. Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats. Hypertension. 2005;45:270-275.
    • (2005) Hypertension , vol.45 , pp. 270-275
    • Hakam, A.C.1    Hussain, T.2
  • 5
    • 0031660492 scopus 로고    scopus 로고
    • Interaction of mRNAs for angiotensin II type 1 and type 2 receptors to vascular remodeling in spontaneously hypertensive rats
    • Otsuka S, Sugano M, Makino N, Sawada S, Hata T, Niho Y. Interaction of mRNAs for angiotensin II type 1 and type 2 receptors to vascular remodeling in spontaneously hypertensive rats. Hypertension. 1998;32:467-472.
    • (1998) Hypertension , vol.32 , pp. 467-472
    • Otsuka, S.1    Sugano, M.2    Makino, N.3    Sawada, S.4    Hata, T.5    Niho, Y.6
  • 7
    • 0033956854 scopus 로고    scopus 로고
    • Role of the angiotensin type 2 receptor in the regulation of blood pressure and renal function
    • Carey RM, Wang ZQ, Siragy HM. Role of the angiotensin type 2 receptor in the regulation of blood pressure and renal function. Hypertension. 2000;35(1 Pt 2):155-163.
    • (2000) Hypertension , vol.35 , Issue.1 PART 2 , pp. 155-163
    • Carey, R.M.1    Wang, Z.Q.2    Siragy, H.M.3
  • 8
    • 20144387642 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptors contribute to vascular responses in spontaneously hypertensive rats treated with angiotensin II type 1 receptor antagonists
    • Cosentino F, Savoia C, De Paolis P, Francia P, Russo A, Maffei A, Venturelli V, Schiavoni M, Lembo G, Volpe M. Angiotensin II type 2 receptors contribute to vascular responses in spontaneously hypertensive rats treated with angiotensin II type 1 receptor antagonists. Am J Hypertens. 2005;18(4 Pt 1):493-499.
    • (2005) Am J Hypertens , vol.18 , Issue.4 PART 1 , pp. 493-499
    • Cosentino, F.1    Savoia, C.2    De Paolis, P.3    Francia, P.4    Russo, A.5    Maffei, A.6    Venturelli, V.7    Schiavoni, M.8    Lembo, G.9    Volpe, M.10
  • 9
    • 18344374044 scopus 로고    scopus 로고
    • Negative regulation of Rho/Rho kinase by angiotensin II type 2 receptor in vascular smooth muscle cells: Role in angiotensin II-induced vasodilation
    • Savoia C, Tabet F, Yao G, Schiffrin EL, Touyz RM. Negative regulation of Rho/Rho kinase by angiotensin II type 2 receptor in vascular smooth muscle cells: role in angiotensin II-induced vasodilation. J Hypertens. 2005;23: 1037-1045.
    • (2005) J Hypertens , vol.23 , pp. 1037-1045
    • Savoia, C.1    Tabet, F.2    Yao, G.3    Schiffrin, E.L.4    Touyz, R.M.5
  • 10
    • 0026409820 scopus 로고
    • Effects of angiotensin subtype 1 and subtype 2 receptor antagonists in normotensive versus hypertensive rats
    • Tofovic SP, Pong AS, Jackson EK. Effects of angiotensin subtype 1 and subtype 2 receptor antagonists in normotensive versus hypertensive rats. Hypertension. 1991;18:774-782.
    • (1991) Hypertension , vol.18 , pp. 774-782
    • Tofovic, S.P.1    Pong, A.S.2    Jackson, E.K.3
  • 11
    • 18244407290 scopus 로고    scopus 로고
    • Cardiovascular and renal regulation by the angiotensin type 2 receptor: The AT2 receptor comes of age
    • Carey RM. Cardiovascular and renal regulation by the angiotensin type 2 receptor: the AT2 receptor comes of age. Hypertension. 2005;45:840-844.
    • (2005) Hypertension , vol.45 , pp. 840-844
    • Carey, R.M.1
  • 12
    • 0032466957 scopus 로고    scopus 로고
    • Vasodilation mediated by angiotensin II type 2 receptor is impaired in afferent arterioles of young spontaneously hypertensive rats
    • Endo Y, Arima S, Yaoita H, Tsunoda K, Omata K, Ito S. Vasodilation mediated by angiotensin II type 2 receptor is impaired in afferent arterioles of young spontaneously hypertensive rats. J Vasc Res. 1998;35:421-427.
    • (1998) J Vasc Res , vol.35 , pp. 421-427
    • Endo, Y.1    Arima, S.2    Yaoita, H.3    Tsunoda, K.4    Omata, K.5    Ito, S.6
  • 13
    • 41149099225 scopus 로고    scopus 로고
    • Angiotensin AT2 receptors: Control of renal sodium excretion and blood pressure
    • Carey RM, Padia SH. Angiotensin AT2 receptors: control of renal sodium excretion and blood pressure. Trends Endocrinol Metab. 2008;19:84-87.
    • (2008) Trends Endocrinol Metab , vol.19 , pp. 84-87
    • Carey, R.M.1    Padia, S.H.2
  • 14
    • 84856097765 scopus 로고    scopus 로고
    • Sex-specific influence of angiotensin type 2 receptor stimulation on renal function: A novel therapeutic target for hypertension
    • Hilliard LM, Jones ES, Steckelings UM, Unger T, Widdop RE, Denton KM. Sex-specific influence of angiotensin type 2 receptor stimulation on renal function: a novel therapeutic target for hypertension. Hypertension. 2012;59:409-414.
    • (2012) Hypertension , vol.59 , pp. 409-414
    • Hilliard, L.M.1    Jones, E.S.2    Steckelings, U.M.3    Unger, T.4    Widdop, R.E.5    Denton, K.M.6
  • 15
    • 8644281991 scopus 로고    scopus 로고
    • Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist
    • Wan Y, Wallinder C, Plouffe B, et al. Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist. J Med Chem. 2004;47:5995-6008.
    • (2004) J Med Chem. , vol.47 , pp. 5995-6008
    • Wan, Y.1    Wallinder, C.2    Plouffe, B.3
  • 16
    • 3242892150 scopus 로고    scopus 로고
    • AT2 receptor-mediated vasodilatation is unmasked by AT1 receptor blockade in conscious SHR
    • Li XC, Widdop RE. AT2 receptor-mediated vasodilatation is unmasked by AT1 receptor blockade in conscious SHR. Br J Pharmacol. 2004;142: 821-830.
    • (2004) Br J Pharmacol , vol.142 , pp. 821-830
    • Li, X.C.1    Widdop, R.E.2
  • 19
    • 0032733920 scopus 로고    scopus 로고
    • AT(2) receptor stimulation enhances antihypertensive effect of AT(1) receptor antagonist in hypertensive rats
    • Barber MN, Sampey DB, Widdop RE. AT(2) receptor stimulation enhances antihypertensive effect of AT(1) receptor antagonist in hypertensive rats. Hypertension. 1999;34:1112-1116.
    • (1999) Hypertension , vol.34 , pp. 1112-1116
    • Barber, M.N.1    Sampey, D.B.2    Widdop, R.E.3
  • 20
    • 84856120678 scopus 로고    scopus 로고
    • Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats
    • Rehman A, Leibowitz A, Yamamoto N, Rautureau Y, Paradis P, Schiffrin EL. Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats. Hypertension. 2012;59:291-299.
    • (2012) Hypertension , vol.59 , pp. 291-299
    • Rehman, A.1    Leibowitz, A.2    Yamamoto, N.3    Rautureau, Y.4    Paradis, P.5    Schiffrin, E.L.6
  • 21
    • 76449117787 scopus 로고    scopus 로고
    • Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats
    • Bosnyak S, Welungoda IK, Hallberg A, Alterman M, Widdop RE, Jones ES. Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats. Br J Pharmacol. 2010;159:709-716.
    • (2010) Br J Pharmacol , vol.159 , pp. 709-716
    • Bosnyak, S.1    Welungoda, I.K.2    Hallberg, A.3    Alterman, M.4    Widdop, R.E.5    Jones, E.S.6
  • 23
    • 0032891343 scopus 로고    scopus 로고
    • Differential regulation of renal angiotensin subtype AT1A and AT2 receptor protein in rats with angiotensin-dependent hypertension
    • Wang ZQ, Millatt LJ, Heiderstadt NT, Siragy HM, Johns RA, Carey RM. Differential regulation of renal angiotensin subtype AT1A and AT2 receptor protein in rats with angiotensin-dependent hypertension. Hypertension. 1999;33:96-101.
    • (1999) Hypertension , vol.33 , pp. 96-101
    • Wang, Z.Q.1    Millatt, L.J.2    Heiderstadt, N.T.3    Siragy, H.M.4    Johns, R.A.5    Carey, R.M.6
  • 24
    • 84865499511 scopus 로고    scopus 로고
    • Why do we need a selective angiotensin II type 2 receptor agonist?
    • Henrion D. Why do we need a selective angiotensin II type 2 receptor agonist? Hypertension. 2012;60:616-617.
    • (2012) Hypertension , vol.60 , pp. 616-617
    • Henrion, D.1
  • 25
    • 14844346472 scopus 로고    scopus 로고
    • High blood pressure reduction reverses angiotensin II type 2 receptor-mediated vasoconstriction into vasodilation in spontaneously hypertensive rats
    • You D, Loufrani L, Baron C, Levy BI, Widdop RE, Henrion D. High blood pressure reduction reverses angiotensin II type 2 receptor-mediated vasoconstriction into vasodilation in spontaneously hypertensive rats. Circulation. 2005;111:1006-1011.
    • (2005) Circulation , vol.111 , pp. 1006-1011
    • You, D.1    Loufrani, L.2    Baron, C.3    Levy, B.I.4    Widdop, R.E.5    Henrion, D.6
  • 27
    • 84861100730 scopus 로고    scopus 로고
    • Angiotensin II AT(2) receptor decreases AT(1) receptor expression and function via nitric oxide/cGMP/Sp1 in renal proximal tubule cells from Wistar-Kyoto rats
    • Yang J, Chen C, Ren H, Han Y, He D, Zhou L, Hopfer U, Jose PA, Zeng C. Angiotensin II AT(2) receptor decreases AT(1) receptor expression and function via nitric oxide/cGMP/Sp1 in renal proximal tubule cells from Wistar-Kyoto rats. J Hypertens. 2012;30:1176-1184.
    • (2012) J Hypertens , vol.30 , pp. 1176-1184
    • Yang, J.1    Chen, C.2    Ren, H.3    Han, Y.4    He, D.5    Zhou, L.6    Hopfer, U.7    Jose, P.A.8    Zeng, C.9
  • 28
    • 0036771844 scopus 로고    scopus 로고
    • AT2 receptor-mediated relaxation is preserved after long-term AT1 receptor blockade
    • Widdop RE, Matrougui K, Levy BI, Henrion D. AT2 receptor-mediated relaxation is preserved after long-term AT1 receptor blockade. Hypertension. 2002;40:516-520.
    • (2002) Hypertension , vol.40 , pp. 516-520
    • Widdop, R.E.1    Matrougui, K.2    Levy, B.I.3    Henrion, D.4
  • 29
    • 33846427712 scopus 로고    scopus 로고
    • Angiotensin type 2 receptor in resistance arteries of type 2 diabetic hypertensive patients
    • Savoia C, Touyz RM, Volpe M, Schiffrin EL. Angiotensin type 2 receptor in resistance arteries of type 2 diabetic hypertensive patients. Hypertension. 2007;49:341-346.
    • (2007) Hypertension , vol.49 , pp. 341-346
    • Savoia, C.1    Touyz, R.M.2    Volpe, M.3    Schiffrin, E.L.4
  • 30
    • 0141834774 scopus 로고    scopus 로고
    • Effect of angiotensin AT2 receptor stimulation on vascular cyclic GMP production in normotensive Wistar Kyoto rats
    • Pees C, Unger T, Gohlke P. Effect of angiotensin AT2 receptor stimulation on vascular cyclic GMP production in normotensive Wistar Kyoto rats. Int J Biochem Cell Biol. 2003;35:963-972.
    • (2003) Int J Biochem Cell Biol , vol.35 , pp. 963-972
    • Pees, C.1    Unger, T.2    Gohlke, P.3
  • 31
    • 33750575906 scopus 로고    scopus 로고
    • Angiotensin II/AT2 receptor-induced vasodilation in stroke-prone spontaneously hypertensive rats involves nitric oxide and cGMP-dependent protein kinase
    • Savoia C, Ebrahimian T, He Y, Gratton JP, Schiffrin EL, Touyz RM. Angiotensin II/AT2 receptor-induced vasodilation in stroke-prone spontaneously hypertensive rats involves nitric oxide and cGMP-dependent protein kinase. J Hypertens. 2006;24:2417-2422.
    • (2006) J Hypertens , vol.24 , pp. 2417-2422
    • Savoia, C.1    Ebrahimian, T.2    He, Y.3    Gratton, J.P.4    Schiffrin, E.L.5    Touyz, R.M.6
  • 32
    • 59849116222 scopus 로고    scopus 로고
    • Intrarenal angiotensin III infusion induces natriuresis and angiotensin type 2 receptor translocation in Wistar-Kyoto but not in spontaneously hypertensive rats
    • Padia SH, Kemp BA, Howell NL, Gildea JJ, Keller SR, Carey RM. Intrarenal angiotensin III infusion induces natriuresis and angiotensin type 2 receptor translocation in Wistar-Kyoto but not in spontaneously hypertensive rats. Hypertension. 2009;53:338-343.
    • (2009) Hypertension , vol.53 , pp. 338-343
    • Padia, S.H.1    Kemp, B.A.2    Howell, N.L.3    Gildea, J.J.4    Keller, S.R.5    Carey, R.M.6
  • 33
    • 84873035303 scopus 로고    scopus 로고
    • AT2 receptors: Beneficial counter-regulatory role in cardiovascular and renal function
    • Padia SH, Carey RM. AT2 receptors: beneficial counter-regulatory role in cardiovascular and renal function. Pflugers Arch. 2013;465:99-110.
    • (2013) Pflugers Arch , vol.465 , pp. 99-110
    • Padia, S.H.1    Carey, R.M.2
  • 34
    • 0032728585 scopus 로고    scopus 로고
    • Activation of AT(2) receptors by endogenous angiotensin II is involved in flowinduced dilation in rat resistance arteries
    • Matrougui K, Loufrani L, Heymes C, Lévy BI, Henrion D. Activation of AT(2) receptors by endogenous angiotensin II is involved in flowinduced dilation in rat resistance arteries. Hypertension. 1999;34(4 Pt 1):659-665.
    • (1999) Hypertension , vol.34 , Issue.4 PART 1 , pp. 659-665
    • Matrougui, K.1    Loufrani, L.2    Heymes, C.3    Lévy, B.I.4    Henrion, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.