메뉴 건너뛰기




Volumn 59, Issue 10, 2010, Pages 2540-2548

Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN[1-7][7 DEXTRO ALANINE]; DIPEPTIDYL CARBOXYPEPTIDASE; GLUCOSE;

EID: 77957558776     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-0782     Document Type: Article
Times cited : (170)

References (50)
  • 1
    • 33745845825 scopus 로고    scopus 로고
    • Physiology of local renin-angiotensin systems
    • Paul M, Poyan Mehr A, Kreutz R. Physiology of local renin-angiotensin systems. Physiol Rev 2006;86:747-803
    • (2006) Physiol Rev , vol.86 , pp. 747-803
    • Paul, M.1    Poyan Mehr, A.2    Kreutz, R.3
  • 3
    • 1542374750 scopus 로고    scopus 로고
    • Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets
    • Lau T, Carlsson PO, Leung PS. Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets. Diabetologia 2004;47: 240-248
    • (2004) Diabetologia , vol.47 , pp. 240-248
    • Lau, T.1    Carlsson, P.O.2    Leung, P.S.3
  • 5
    • 0031911742 scopus 로고    scopus 로고
    • And the endocrine pancreas: Effects on islet blood flow and insulin secretion in rats
    • Carlsson PO, Berne C, Jansson L. Angiotensin II and the endocrine pancreas: effects on islet blood flow and insulin secretion in rats. Diabetologia 1998;41:127-133
    • (1998) Diabetologia , vol.41 , pp. 127-133
    • Carlsson, P.O.1    Berne, C.2    Jansson, L.3    Angiotensin, I.I.4
  • 7
    • 33644596657 scopus 로고    scopus 로고
    • The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets
    • Lupi R, Guerra SD, Bugliani M, Boggi U, Mosca F, Torri S, Prato SD, Marchetti P. The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets. Eur J Endocrinol 2006;154:355-361
    • (2006) Eur J Endocrinol , vol.154 , pp. 355-361
    • Lupi, R.1    Guerra, S.D.2    Bugliani, M.3    Boggi, U.4    Mosca, F.5    Torri, S.6    Prato, S.D.7    Marchetti, P.8
  • 9
    • 33644781780 scopus 로고    scopus 로고
    • 2-cell function and glucose tolerance in a mouse model of type 2 diabetes
    • 2-cell function and glucose tolerance in a mouse model of type 2 diabetes. Diabetes 2006;55:367-374
    • (2006) Diabetes , vol.55 , pp. 367-374
    • Chu, K.Y.1    Lau, T.2    Carlsson, P.-O.3    Leung, P.S.4
  • 11
    • 62949127898 scopus 로고    scopus 로고
    • The sweeter side of ACE2: Physiological evidence for a role in diabetes
    • Bindom S, Lazartigues E. The sweeter side of ACE2: physiological evidence for a role in diabetes. Mol Cell Endocrinol 2009;302:193-202
    • (2009) Mol Cell Endocrinol , vol.302 , pp. 193-202
    • Bindom, S.1    Lazartigues, E.2
  • 13
    • 0034721906 scopus 로고    scopus 로고
    • A human homolog of angiotensin-converting enzyme: Cloning and functional expression as a captopril-insensitive carboxypeptidase
    • Tipnis SR, Hooper NM, Hyde R, Karran E, Christie G, Turner AJ. A human homolog of angiotensin-converting enzyme: cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem 2000;275: 33238-33243
    • (2000) J Biol Chem , vol.275 , pp. 33238-33243
    • Tipnis, S.R.1    Hooper, N.M.2    Hyde, R.3    Karran, E.4    Christie, G.5    Turner, A.J.6
  • 16
  • 18
    • 65449152678 scopus 로고    scopus 로고
    • Loss of angiotensin-converting enzyme 2 leads to impaired glucose homeostasis in mice
    • Niu MJ, Yang JK, Lin SS, Ji XJ, Guo LM. Loss of angiotensin-converting enzyme 2 leads to impaired glucose homeostasis in mice. Endocrine 2008;34:56-61
    • (2008) Endocrine , vol.34 , pp. 56-61
    • Niu, M.J.1    Yang, J.K.2    Lin, S.S.3    Ji, X.J.4    Guo, L.M.5
  • 19
    • 0036314864 scopus 로고    scopus 로고
    • Is reduced first-phase insulin release the earliest detectable abnormality in individuals destined to develop type 2 diabetes?
    • Gerich JE. Is reduced first-phase insulin release the earliest detectable abnormality in individuals destined to develop type 2 diabetes? Diabetes 2002;51:S117-S121
    • (2002) Diabetes , vol.51
    • Gerich, J.E.1
  • 21
    • 62949121839 scopus 로고    scopus 로고
    • ACE2 over-expression in the subfornical organ prevents the angiotensin-II-mediated pressor and drinking responses and is associated with AT1 receptor down-regulation
    • Feng Y, Yue X, Xia H, Bindom SM, Hickman P, Filipeanu C, Wu G, Lazartigues E. ACE2 over-expression in the subfornical organ prevents the angiotensin-II-mediated pressor and drinking responses and is associated with AT1 receptor down-regulation. Circ Res 2008;102:628-629
    • (2008) Circ Res , vol.102 , pp. 628-629
    • Feng, Y.1    Yue, X.2    Xia, H.3    Bindom, S.M.4    Hickman, P.5    Filipeanu, C.6    Wu, G.7    Lazartigues, E.8
  • 22
    • 2342472108 scopus 로고    scopus 로고
    • Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: A renoprotective combination?
    • Ye M, Wysocki J, Naaz P, Salabat MR, LaPointe MS, Batlle D. Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination? Hypertension 2004;43:1120-1125
    • (2004) Hypertension , vol.43 , pp. 1120-1125
    • Ye, M.1    Wysocki, J.2    Naaz, P.3    Salabat, M.R.4    LaPointe, M.S.5    Batlle, D.6
  • 24
    • 0020045888 scopus 로고
    • Diabetes-obesity syndromes in mice
    • Coleman D. Diabetes-obesity syndromes in mice. Diabetes 1982;32:1-6
    • (1982) Diabetes , vol.32 , pp. 1-6
    • Coleman, D.1
  • 25
    • 0034089010 scopus 로고    scopus 로고
    • Viral vectors for gene delivery and gene therapy within the endocrine system
    • Stone D, David A, Bolognani F, Lowenstein PR, Castro MG. Viral vectors for gene delivery and gene therapy within the endocrine system. J Endocrinol 2000;164:103-118
    • (2000) J Endocrinol , vol.164 , pp. 103-118
    • Stone, D.1    David, A.2    Bolognani, F.3    Lowenstein, P.R.4    Castro, M.G.5
  • 27
    • 0029933105 scopus 로고    scopus 로고
    • Adenovirus-mediated in vivo gene transfer and expression in normal rat pancreas
    • Raper S, DeMatteo R. Adenovirus-mediated in vivo gene transfer and expression in normal rat pancreas. Pancreas 1996;12:401-410
    • (1996) Pancreas , vol.12 , pp. 401-410
    • Raper, S.1    DeMatteo, R.2
  • 28
    • 0030983596 scopus 로고    scopus 로고
    • Functional cnsequences of adenovirus-mediated murine pancreatic gene transfer
    • McClane SJ, Hamilton TE, Burke CV, Raper SE. Functional cnsequences of adenovirus-mediated murine pancreatic gene transfer. Human Gene Ther 1997;8:739-746
    • (1997) Human Gene Ther , vol.8 , pp. 739-746
    • McClane, S.J.1    Hamilton, T.E.2    Burke, C.V.3    Raper, S.E.4
  • 29
    • 0036178032 scopus 로고    scopus 로고
    • Selective gene transfer to key cardiovascular regions of the brain: Comparison of two viral vector systems
    • Sinnayah P, Lindley TE, Staber PD, Cassell MD, Davidson BL, Davisson RL. Selective gene transfer to key cardiovascular regions of the brain: comparison of two viral vector systems. Hypertension 2002;39:603-608
    • (2002) Hypertension , vol.39 , pp. 603-608
    • Sinnayah, P.1    Lindley, T.E.2    Staber, P.D.3    Cassell, M.D.4    Davidson, B.L.5    Davisson, R.L.6
  • 33
    • 57349099271 scopus 로고    scopus 로고
    • 2-(1H-tetrazol-5-yl)-[1,1′]-biphenyl]- 4-yl]methyl]-L-valine enhances pancreatic islet morphology and function in a mouse model of type 2 diabetes
    • 2-(1H-tetrazol-5- yl)-[1,1′]-biphenyl]- 4-yl]methyl]-L-valine] enhances pancreatic islet morphology and function in a mouse model of type 2 diabetes. J Pharmacol Exp Ther 2008;327:683-691
    • (2008) J Pharmacol Exp Ther , vol.327 , pp. 683-691
    • Cheng, Q.1    Law, P.K.2    De Gasparo, M.3    Leung, P.S.4
  • 34
    • 34047256118 scopus 로고    scopus 로고
    • Angiotensin-(1-7) inhibits growth of human lung adenocarcinoma xenografts in nude mice through a reduction in cyclooxygenase- 2
    • Menon J, Soto-Pantoja DR, Callahan MF, Cline JM, Ferrario CM, Tallant EA, Gallagher PE. Angiotensin-(1-7) inhibits growth of human lung adenocarcinoma xenografts in nude mice through a reduction in cyclooxygenase- 2. Cancer Res 2007;67:2809-2815
    • (2007) Cancer Res , vol.67 , pp. 2809-2815
    • Menon, J.1    Soto-Pantoja, D.R.2    Callahan, M.F.3    Cline, J.M.4    Ferrario, C.M.5    Tallant, E.A.6    Gallagher, P.E.7
  • 35
    • 25444473110 scopus 로고    scopus 로고
    • Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor
    • Tallant EA, Ferrario CM, Gallagher PE. Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor. Am J Physiol Heart Circ Physiol 2005;289:H1560-H1566
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Tallant, E.A.1    Ferrario, C.M.2    Gallagher, P.E.3
  • 36
    • 60549095158 scopus 로고    scopus 로고
    • Angiotensin-(1-7) activates growth stimulatory pathways in human mesangial cells
    • Zimpelmann J, Burns KD. Angiotensin-(1-7) activates growth stimulatory pathways in human mesangial cells. Am J Physiol Renal Physiol 2009;296: F337-346
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Zimpelmann, J.1    Burns, K.D.2
  • 39
    • 0035907347 scopus 로고    scopus 로고
    • Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homolog of ACE2 and is developmentally regulated in embryonic kidneys
    • Zhang H, Wada J, Hida K, Tsuchiyama Y, Hiragushi K, Shikata K, Wang H, Lin S, Kanwar YS, Makino H. Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homolog of ACE2 and is developmentally regulated in embryonic kidneys. J Biol Chem 2001;276:17132-17139
    • (2001) J Biol Chem , vol.276 , pp. 17132-17139
    • Zhang, H.1    Wada, J.2    Hida, K.3    Tsuchiyama, Y.4    Hiragushi, K.5    Shikata, K.6    Wang, H.7    Lin, S.8    Kanwar, Y.S.9    Makino, H.10
  • 41
    • 33644875891 scopus 로고    scopus 로고
    • Tmem27. A cleaved and shed plasma membrane protein that stimulates pancreatic beta cell proliferation
    • Akpinar P, Kuwajima S, Krutzfeldt J, Stoffel M. Tmem27. A cleaved and shed plasma membrane protein that stimulates pancreatic beta cell proliferation. Cell Metabolism 2005;2:385-397
    • (2005) Cell Metabolism , vol.2 , pp. 385-397
    • Akpinar, P.1    Kuwajima, S.2    Krutzfeldt, J.3    Stoffel, M.4
  • 43
    • 77957599185 scopus 로고    scopus 로고
    • LVAD therapy up-regulates ACE-2 but may decrease apoptosis and mediate reverse remodeling via a "non ang 1-7 non mas receptor" pathway in patients with end stage heart failure
    • Abstract
    • Chandrashekhar Y, Anway R, Godavarthy A, Shekels L. LVAD therapy up-regulates ACE-2 but may decrease apoptosis and mediate reverse remodeling via a "non ang 1-7 non mas receptor" pathway in patients with end stage heart failure (Abstract). Circulation 2007;116:II-454
    • (2007) Circulation , vol.116
    • Chandrashekhar, Y.1    Anway, R.2    Godavarthy, A.3    Shekels, L.4
  • 44
    • 34250333856 scopus 로고    scopus 로고
    • 2- cell function in young type 2 diabetic mice
    • 2-cell function in young type 2 diabetic mice. Antioxid Redox Signal 2007;9:869-878
    • (2007) Antioxid Redox Signal , vol.9 , pp. 869-878
    • Chu, K.Y.1    Leung, P.S.2
  • 45
    • 34447627156 scopus 로고    scopus 로고
    • Differential role of kinin B1 and B2 receptors in ischemia-induced apoptosis and ventricular remodeling
    • Yin H, Chao J, Bader M, Chao L. Differential role of kinin B1 and B2 receptors in ischemia-induced apoptosis and ventricular remodeling. Peptides 2007;28:1383-1389
    • (2007) Peptides , vol.28 , pp. 1383-1389
    • Yin, H.1    Chao, J.2    Bader, M.3    Chao, L.4
  • 46
    • 0033778471 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokineinduced apoptosis in purified rat pancreatic beta-cells
    • Pavlovic D, Andersen N, Mandrup-Poulsen T, Eizirik D. Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokineinduced apoptosis in purified rat pancreatic beta-cells. Eur Cytokine Netw 2000;11:267-274
    • (2000) Eur Cytokine Netw , vol.11 , pp. 267-274
    • Pavlovic, D.1    Andersen, N.2    Mandrup-Poulsen, T.3    Eizirik, D.4
  • 48
    • 33745863033 scopus 로고    scopus 로고
    • Islet beta cell failure in type 2 diabetes
    • Prentki M, Nolan CJ. Islet beta cell failure in type 2 diabetes. J Clin Invest 2006;116:1802-1812
    • (2006) J Clin Invest , vol.116 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 49
    • 0034853485 scopus 로고    scopus 로고
    • The importance of {beta}-cell failure in the development and progression of type 2 diabetes
    • Kahn SE. The importance of {beta}-cell failure in the development and progression of type 2 diabetes. J Clin Endocrinol Metab 2001;86:4047-4058
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4047-4058
    • Kahn, S.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.