Stochastic model of endothelial TRPV4 calcium sparklets: Effect of bursting and cooperativity on EDH

Biophysical Journal

Volumn 108, Issue 6, 2015, Pages 1566-1576

  Parikh, Jaimit ^a   Kapela, Adam ^a   Tsoukias, Nikolaos M ^a,b  

^a Florida International University   (United States)

^b NATIONAL TECHNICAL UNIVERSITY OF ATHENS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM ACTIVATED POTASSIUM CHANNEL; VANILLOID RECEPTOR;

COMPUTER SIMULATION; ENDOTHELIUM CELL; KINETICS; MARKOV CHAIN; METABOLISM; MOLECULAR MODEL;

CALCIUM; COMPUTER SIMULATION; ENDOTHELIAL CELLS; KINETICS; MARKOV CHAINS; MODELS, MOLECULAR; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; STOCHASTIC PROCESSES; TRPV CATION CHANNELS;

EID: 84925435032     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2015.01.034     Document Type: Article

References (47)

1. G. Edwards, M. Félétou, and A.H. Weston Endothelium-derived hyperpolarizing factors and associated pathways: a synopsis Pflugers Arch. 459 2010 863 879
2. C.J. Garland, C.R. Hiley, and K.A. Dora EDHF: spreading the influence of the endothelium Br. J. Pharmacol. 164 2011 839 852
3. 2+ events, and IKCa channels, reducing arteriolar tone Proc. Natl. Acad. Sci. USA 109 2012 18174 18179
4. 2+ signals through endothelial TRPV4 channels regulate vascular function Science 336 2012 597 601
5. S.K. Sonkusare, and T. Dalsgaard M.T. Nelson AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension Sci. Signal. 7 2014 ra66
6. S. Heller, and R.G. O'Neil Chapter 8. Molecular mechanisms of TRPV4 gating TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades 2007 Taylor & Francis London, UK
7. 2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site J. Biol. Chem. 278 2003 26541 26549
8. B. Nilius, and J. Vriens T. Voets TRPV4 calcium entry channel: a paradigm for gating diversity Am. J. Physiol. Cell Physiol. 286 2004 C195 C205
9. S. Earley, and T. Pauyo J.E. Brayden TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure Am. J. Physiol. Heart Circ. Physiol. 297 2009 H1096 H1102
10. 2+ influx and vasodilation in response to shear stress Am. J. Physiol. Heart Circ. Physiol. 298 2010 H466 H476
11. H. Watanabe, and J. Vriens B. Nilius Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells J. Biol. Chem. 277 2002 47044 47051
12. S.L. Sandow, and R.E. Haddock F. Plane What's where and why at a vascular myoendothelial microdomain signaling complex Clin. Exp. Pharmacol. Physiol. 36 2009 67 76
13. K.R. Heberlein, A.C. Straub, and B.E. Isakson The myoendothelial junction: breaking through the matrix? Microcirculation 16 2009 307 322
14. P.M. Kerr, and R. Tam F. Plane Endothelial feedback and the myoendothelial projection Microcirculation 19 2012 416 422
15. Ca) and connexins: possible relationship to vasodilator function? J. Anat. 209 2006 689 698
16. J. Ledoux, and M.S. Taylor M.T. Nelson Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections Proc. Natl. Acad. Sci. USA 105 2008 9627 9632
17. 2+ communication J. Cell Sci. 121 2008 3664 3673
18. K.A. Dora, and N.T. Gallagher C.J. Garland Modulation of endothelial cell KCa3.1 channels during endothelium-derived hyperpolarizing factor signaling in mesenteric resistance arteries Circ. Res. 102 2008 1247 1255
19. 2+ wavelets and the induction of myoendothelial feedback Am. J. Physiol. Cell Physiol. 302 2012 C1226 C1242
20. A. Kapela, A. Bezerianos, and N.M. Tsoukias A mathematical model of vasoreactivity in rat mesenteric arterioles: I. Myoendothelial communication Microcirculation 16 2009 694 713
21. H.S. Silva, A. Kapela, and N.M. Tsoukias A mathematical model of plasma membrane electrophysiology and calcium dynamics in vascular endothelial cells Am. J. Physiol. Cell Physiol. 293 2007 C277 C293
22. 2+ dynamics in rat mesenteric smooth muscle cell: agonist and NO stimulation J. Theor. Biol. 253 2008 238 260
23. S. Nagaraja, and A. Kapela N.M. Tsoukias Role of microprojections in myoendothelial feedback - a theoretical study J. Physiol. 591 2013 2795 2812
24. J.C. Brasen, J.C. Jacobsen, and N.H. Holstein-Rathlou The nanostructure of myoendothelial junctions contributes to signal rectification between endothelial and vascular smooth muscle cells PLoS ONE 7 2012 e33632
25. A. Kapela, and N.M. Tsoukias Multiscale FEM modeling of vascular tone: from membrane currents to vessel mechanics IEEE Trans. Biomed. Eng. 58 2011 3456 3459
26. S. Loukin, and X. Zhou C. Kung Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force J. Biol. Chem. 285 2010 27176 27181
27. X. Ma, and B. Nilius X. Yao Electrophysiological properties of heteromeric TRPV4-C1 channels Biochim. Biophys. Acta 1808 2011 2789 2797
28. D. Colquhoun, and A.G. Hawkes On the stochastic properties of bursts of single ion channel openings and of clusters of bursts Philos. Trans. R. Soc. Lond. B Biol. Sci. 300 1982 1 59
29. F.G. Ball, and J.A. Rice Stochastic models for ion channels: introduction and bibliography Math. Biosci. 112 1992 189 206
30. D. Colquhoun, and A.G. Hawkes On the stochastic properties of single ion channels Proc. R. Soc. Lond. B Biol. Sci. 211 1981 205 235
31. + current in mouse aortic endothelial cells Pflugers Arch. 447 2004 426 435
32. + channels in the tonoplast of Chara corallina Biophys. J. 65 1993 1553 1559
33. + channel in porcine coronary endothelium: relevance to EDHF Br. J. Pharmacol. 137 2002 1346 1354
34. Y. Yamamoto, and M.F. Klemm H. Suzuki Intercellular electrical communication among smooth muscle and endothelial cells in guinea-pig mesenteric arterioles J. Physiol. 535 2001 181 195
35. B. Nilius, and G. Droogmans Ion channels and their functional role in vascular endothelium Physiol. Rev. 81 2001 1415 1459
36. S. Nagaraja, A. Kapela, and N.M. Tsoukias Intercellular communication in the vascular wall: a modeling perspective Microcirculation 19 2012 391 402
37. 2+ signaling in the microcirculation: intercellular communication and vasoreactivity Crit. Rev. Biomed. Eng. 39 2011 435 460
38. X.J. Yuan, and W.F. Goldman M.P. Blaustein Ionic currents in rat pulmonary and mesenteric arterial myocytes in primary culture and subculture Am. J. Physiol. 264 1993 L107 L115
39. A. Kapela, S. Nagaraja, and N.M. Tsoukias A mathematical model of vasoreactivity in rat mesenteric arterioles. II. Conducted vasoreactivity Am. J. Physiol. Heart Circ. Physiol. 298 2010 H52 H65
40. T.M. Ishii, and C. Silvia J. Maylie A human intermediate conductance calcium-activated potassium channel Proc. Natl. Acad. Sci. USA 94 1997 11651 11656
41. + channels Circ. Res. 104 2009 987 994
42. S. Earley, A.L. Gonzales, and Z.I. Garcia A dietary agonist of transient receptor potential cation channel V3 elicits endothelium-dependent vasodilation Mol. Pharmacol. 77 2010 612 620
43. K.W. Buchan, and W. Martin Modulation of agonist-induced calcium mobilization in bovine aortic endothelial cells by phorbol myristate acetate and cyclic AMP but not cyclic GMP Br. J. Pharmacol. 104 1991 361 366
44. 2+ signals and gap junction function are regulated by caveolin in endothelial cells Circulation 117 2008 1065 1074
45. 2+: molecular determinants and functional consequences Physiol. Rev. 86 2006 369 408
46. + channels provide different facets of endothelium-dependent hyperpolarization in rat mesenteric artery J. Physiol. 553 2003 183 189
47. A.M. Keleshian, and G.F. Yeo B.W. Madsen Superposition properties of interacting ion channels Biophys. J. 67 1994 634 640